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Cat. No.: HY-146206

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HCAIX-IN-1

HCAIX-IN-1 (compound 21e) is a potent and selective HCAIX inhibitor with K_Is of 694.9, 126.6, 3.3, 9.8 nM for hCA I, hCA II, hCA IX, hCA XII, respectively.

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CAS No.: 2389034-65-3
Formule: C₁₆H₁₇N₇O₄S
Masse moléculaire:403.42

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

HCAIX-IN-1 Chemical Structure

CAS No.: 2389034-65-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

HCAIX-IN-1 (compound 21e) is a potent and selective HCAIX inhibitor with K_Is of 694.9, 126.6, 3.3, 9.8 nM for hCA I, hCA II, hCA IX, hCA XII, respectively^[1].

IC₅₀ & Target^[1]

hCA I

694.9 nM (Ki)

hCA II

126.6 nM (Ki)

hCA IX

3.3 nM (Ki)

hCA XII

9.8 nM (Ki)

Voir tous les produits spécifiques à Isoform Carbonic Anhydrase :

Chemical Information

CAS No. 2389034-65-3
Masse moléculaire 403.42
Formule C₁₆H₁₇N₇O₄S
SMILES

COC1=CC=C(C=C1)NC(NC2=NN(C(N)=N2)C3=CC=C(C=C3)S(N)(=O)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Said MA,et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843. [Content Brief]

Calculators

Calculateur de molarité

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Calculateur de dilution

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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HCAIX-IN-1

Voir tous les produits spécifiques à Isoform Carbonic Anhydrase

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

HCAIX-IN-1 Related Classifications

HY-146206 Related Classifications