2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. HCAIX-IN-1

HCAIX-IN-1 (compound 21e) is a potent and selective HCAIX inhibitor with KIs of 694.9, 126.6, 3.3, 9.8 nM for hCA I, hCA II, hCA IX, hCA XII, respectively.

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HCAIX-IN-1 Chemical Structure

HCAIX-IN-1 Chemical Structure

CAS No. : 2389034-65-3

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HCAIX-IN-1 Related Antibodies

Top Publications Citing Use of Products

View All Carbonic Anhydrase Isoform Specific Products:

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CA CA I CA Ⅱ CA Ⅸ CA XII

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Description

HCAIX-IN-1 (compound 21e) is a potent and selective HCAIX inhibitor with KIs of 694.9, 126.6, 3.3, 9.8 nM for hCA I, hCA II, hCA IX, hCA XII, respectively[1].

IC50 & Target[1]

hCA I

694.9 nM (Ki)

hCA II

126.6 nM (Ki)

hCA IX

3.3 nM (Ki)

hCA XII

9.8 nM (Ki)

Molecular Weight

403.42

Formula

C16H17N7O4S
CAS No.
SMILES

COC1=CC=C(C=C1)NC(NC2=NN(C(N)=N2)C3=CC=C(C=C3)S(N)(=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HCAIX-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HCAIX-IN-12389034-65-3Carbonic AnhydraseCarbonate dehydrataseInhibitorinhibitorinhibit

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