hCAII-IN-10
hCAII-IN-10 (compound 11d) is hCA II inhibitor with the IC50s of 14 nM and 29.2 μM for hCA II and hCA I, respectively. hCAII-IN-10 inhibits cell growth against HT-29 cells with the IC50 of 74 μM. hCAII-IN-10 shows strongly lowered intraocular pressure in the glaucomatous rabbit eye model.
For research use only. We do not sell to patients.
- Formula: C13H21N5O7S
- Molecular Weight:391.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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hCA II 14 nM (IC50) |
hCA I 29.2 μM (IC50) |
Chemical Information
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Molecular Weight 391.40
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Formula C13H21N5O7S
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SMILES
O[C@@H]1[C@@H](CO)O[C@H](NNC(NC2=CC=C(S(N)(=O)=O)C=C2)=O)[C@H](N)[C@H]1O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)