Iron(II) fumarate
Based on 1 Customer Validation
Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia.
For research use only. We do not sell to patients.
- Purity: 95.06%
- CAS No.: 141-01-5
- Formula: C4H2FeO4
- Molecular Weight:169.90
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Storage:
RT, stored under nitrogen.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Iron(II) fumarate (0.32%, 0.64%; 24 h) can restore the metabolic pathway disruption caused by cypermethrin, enhance the tolerance and cell viability of BmN cells to cypermethrin[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:BmN cells
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Concentration:0.32%, 0.64%
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Incubation Time:24 h
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Result:Enhanced cell tolerance to cypermethrin and increased cell viability.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:p50 and 8y silkworm strains[1].
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Dosage:0.32%, 0.64%
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Administration:Oral gavage (p.o.)
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Result:Improved the resistance of silkworms to cypermethrin.
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Animal Model:Male albino rats (clinical average weight = 65 g)[2].
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Dosage:200-2000 mg/kg
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Administration:Oral gavage (p.o.); 4 weeks
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Result:Increased iron content and TBA-RS levels in the liver.
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Animal Model:Yellow River Carp[3].
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Dosage:3% of body weight; 100 mg ferrous fumarate (F) per kilogram feed (g/kg)
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Administration:Oral gavage (p.o.); twice daily; 6 weeks
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Result:Promoted the development of intestinal villi and increased the thickness of the intestinal muscle layer.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 141-01-5
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Appearance Solid
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Molecular Weight 169.90
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Formula C4H2FeO4
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Color Light brown to brown
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SMILES
O=C([O-])/C=C/C([O-])=O.[Fe+2]
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Synonyms
Ferrous fumarate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, stored under nitrogen
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
1M HCl : 5 mg/mL (29.43 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Wang XY, et al. Fumarate mitigates disruption induced by fenpropathrin in the silkworm Bombyx mori (Lepidoptera): A metabolomics study. Insect Sci. 2023 Jun;30(3):789-802. [Content Brief]
[2]. Rimbach G, et al. Liver and colon oxidant status in growing rats fed increasing levels of dietary iron. J Trace Elem Med Biol. 1997 Jun;11(2):99-104. [Content Brief]
[3]. Ren HT, et al. Effect of Spirulina and Ferrous Fumarate on Intestinal Morphology and the Diversity of Gut Microbiota of Yellow River Carp. Biol Trace Elem Res. 2022 Sep;200(9):4142-4149. [Content Brief]
[4]. Zlotkin S, et al. Treatment of anemia with microencapsulated ferrous fumarate plus ascorbic acid supplied as sprinkles to complementary (weaning) foods. Am J Clin Nutr. 2001 Dec;74(6):791-5. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| 1M HCl | 1 mM | 5.8858 mL | 29.4291 mL | 58.8582 mL | 147.1454 mL |
| 5 mM | 1.1772 mL | 5.8858 mL | 11.7716 mL | 29.4291 mL | |
| 10 mM | 0.5886 mL | 2.9429 mL | 5.8858 mL | 14.7145 mL | |
| 15 mM | 0.3924 mL | 1.9619 mL | 3.9239 mL | 9.8097 mL | |
| 20 mM | 0.2943 mL | 1.4715 mL | 2.9429 mL | 7.3573 mL | |
| 25 mM | 0.2354 mL | 1.1772 mL | 2.3543 mL | 5.8858 mL |
Iron(II) fumarate Related Classifications
HY-B1651 Related Classifications
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