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Ferrous bisglycinate 

Cat. No.: HY-130078
Handling Instructions

Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia.

For research use only. We do not sell to patients.

Ferrous bisglycinate Chemical Structure

Ferrous bisglycinate Chemical Structure

CAS No. : 20150-34-9

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1  mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
250 mg USD 50 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia[1][2].

In Vitro

Ferrous bisglycinate (25-200 μM; 2 h) does not affect the Caco-2 cells viability[2].
Ferrous bisglycinate (25 μM; 2 h) increases ferritin content in the Caco-2 cells[2].

Cell Viability Assay[2]

Cell Line: Caco-2 cells
Concentration: 0, 25, 50, 100, 200 μM
Incubation Time: 2 hours
Result: Did not affect the viability of wild-type and divalent metal transporter 1 (DMT1) knockout Caco-2 cells.

Western Blot Analysis[2]

Cell Line: Caco-2 cells
Concentration: 25 μM
Incubation Time: 2 hours
Result: Increased ferritin content and decreased DMT1 expression levels significantly in the wild-type cells.
In Vivo

Ferrous bisglycinate (500 mg/kg iron; p.o.) exerts a protective effect on colitis in mice[3].

Animal Model: Female C57BL/6 mice are induced colitis by dextran sodium sulfate (DSS)[3]
Dosage: 500 mg/kg iron
Administration: P.o. (add to the diet) for 10 days
Result: Had the best survival rates (100%).
Caused the least body lost (9% body loss).
Molecular Weight

201.95

Formula

C₄H₆FeN₂O₄

CAS No.

20150-34-9

SMILES

O=C1[O-][Fe+2]2([O-]C(CN2)=O)NC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O : 35.71 mg/mL (176.83 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9517 mL 24.7586 mL 49.5172 mL
5 mM 0.9903 mL 4.9517 mL 9.9034 mL
10 mM 0.4952 mL 2.4759 mL 4.9517 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

Ferrous bisglycinateOthersironfortificantssupplementsdeficiencyanemiaInhibitorinhibitorinhibit

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Product Name:
Ferrous bisglycinate
Cat. No.:
HY-130078
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