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  3. SK-3-91

SK-3-91 

Cat. No.: HY-137341
Handling Instructions

SK-3-91 is a multi-kinase degrader. SK-3-91 could collectively induce degradation of the largest number of unique kinases (>125 unique kinases).

For research use only. We do not sell to patients.

SK-3-91 Chemical Structure

SK-3-91 Chemical Structure

Size Price Stock
5 mg USD 480 Ask For Quote & Lead Time
10 mg USD 800 Ask For Quote & Lead Time
25 mg USD 1550 Ask For Quote & Lead Time
50 mg USD 2400 Ask For Quote & Lead Time
100 mg USD 3600 Ask For Quote & Lead Time

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Description

SK-3-91 is a multi-kinase degrader. SK-3-91 could collectively induce degradation of the largest number of unique kinases (>125 unique kinases)[1].

Molecular Weight

887.40

Formula

C42H47ClN10O8S

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (225.38 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1269 mL 5.6344 mL 11.2689 mL
5 mM 0.2254 mL 1.1269 mL 2.2538 mL
10 mM 0.1127 mL 0.5634 mL 1.1269 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: 5 mg/mL (5.63 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: 5 mg/mL (5.63 mM); Suspended solution; Need ultrasonic

*All of the co-solvents are available by MCE.
References
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  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
SK-3-91
Cat. No.:
HY-137341
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