EphA1
EphA1 is the founding member of the Eph receptor tyrosine kinase family, originally identified simply as Eph (EPHT1). It is expressed in epithelial and endothelial cells and binds membrane-anchored ephrin-A ligands such as ephrin-A1 and ephrin-A5, triggering bidirectional signaling that reorganizes the actin cytoskeleton and modulates cell adhesion and repulsion. In endothelium, EphA1-ephrin-A1 interactions help control vascular assembly and angiogenic sprouting, and EphA1 levels are altered in several carcinomas, with reported roles in both promoting and restraining tumor cell motility depending on context. Recombinant EphA1 extracellular domain and kinase domain reagents support ephrin-binding studies and phosphotyrosine signaling assays.
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EphA1 Recombinant Proteins (4)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formel: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
