2. Protéines recombinantes
  3. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators Kinases
  4. Ephrin/Eph Family Receptor Tyrosine Kinases Transferases (EC 2) Protein Tyrosine Kinases Pseudokinases TK
  5. Eph Receptors Eph
  6. EphA1
  7. EphA1 Protein, Human (Active, sf9, His, GST)

EphA1 Protein, a receptor tyrosine kinase, engages in bidirectional signaling with membrane-bound ephrin-A ligands. Activation by EFNA1 regulates cell attachment, motility, angiogenesis, and proliferation. EphA1 may also play a role in apoptosis. EphA1 Protein, Human (sf9, His, GST) is the recombinant human-derived EphA1, expressed by Sf9 insect cells, with His, GST labeled tag. The total length of EphA1 Protein, Human (sf9, His, GST) is 409 a.a..

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Description

EphA1 Protein, a receptor tyrosine kinase, engages in bidirectional signaling with membrane-bound ephrin-A ligands. Activation by EFNA1 regulates cell attachment, motility, angiogenesis, and proliferation. EphA1 may also play a role in apoptosis. EphA1 Protein, Human (sf9, His, GST) is the recombinant human-derived EphA1, expressed by Sf9 insect cells, with His, GST labeled tag. The total length of EphA1 Protein, Human (sf9, His, GST) is 409 a.a..
Background

EphA1 protein is a receptor tyrosine kinase that interacts with membrane-bound ephrin-A ligands on neighboring cells, resulting in contact-dependent bidirectional signaling. This receptor mediates both forward signaling and reverse signaling pathways. Activation by its high-affinity ligand EFNA1 regulates various cellular processes, including cell attachment, motility, angiogenesis, and proliferation. Additionally, EphA1 may play a role in apoptosis.
Species

Human
Source

Sf9 insect cells
Tag

His;GST
Accession

P21709-1 (F568-D976)
Gene ID

2041
Protein Length

Partial
Synonyms
EPHA1; Eph receptor A1; ephrin type-A receptor 1; mEpha1; embryonic stem cell kinase; tyrosine-protein kinase receptor ESK; Eph; Esk; AL033318; 5730453L17Rik
AA Sequence

FRSRRAQRQRQQRQRDRATDVDREDKLWLKPYVDLQAYEDPAQGALDFTRELDPAWLMVDTVIGEGEFGEVYRGTLRLPSQDCKTVAIKTLKDTSPGGQWWNFLREATIMGQFSHPHILHLEGVVTKRKPIMIITEFMENGALDAFLREREDQLVPGQLVAMLQGIASGMNYLSNHNYVHRDLAARNILVNQNLCCKVSDFGLTRLLDDFDGTYETQGGKIPIRWTAPEAIAHRIFTTASDVWSFGIVMWEVLSFGDKPYGEMSNQEVMKSIEDGYRLPPPVDCPAPLYELMKNCWAYDRARRPHFQKLQAHLEQLLANPHSLRTIANFDPRMTLRLPSLSGSDGIPYRTVSEWLESIRMKRYILHFHSAGLDTMECVLELTAEDLTQMGITLPGHQKRILCSIQGFKD

Pureté

≥ 80%, as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Instruction de manipulation (2659 KB)

EphA1 Protein, Human (Active, sf9, His, GST) Related Classifications

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