2443816-45-1
2443816-45-1
Chemical Structure
ULK-101
- CAS No.: 2443816-45-1
- Formula:C22H16F4N4OS
- Molecular Weight:460.45
IUPAC Name: (S)-N-(1-cyclopropyl-2,2,2-trifluoroethyl)-4-(6-(4-fluorophenyl)pyrazolo[1,5-a]pyrimidin-3-yl)thiophene-2-carboxamide
InChIKey: PFZRXJIYAFANHP-IBGZPJMESA-N
SMILES: FC1=CC=C(C(C=N2)=CN3C2=C(C4=CSC(C(N[C@@H](C5CC5)C(F)(F)F)=O)=C4)C=N3)C=C1
Biological Activity: ULK-101 is a potent and selective ULK1 inhibitor, with IC50 values of 1.6 nM and 30 nM for ULK1 and ULK2, respectively. ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ULK-101 | 99.91% | ULK-101 is a potent and selective ULK1 inhibitor, with IC50 values of 1.6 nM and 30 nM for ULK1 and ULK2, respectively. ULK-101 suppresses autophagy and sensitizes cancer cells to nutrient stress. | ||||||||||||||||||||
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References
Keywords
