1. Apoptosis
  2. RIP kinase
  3. GSK2983559

GSK2983559 

Cat. No.: HY-112038A Purity: 99.24%
Handling Instructions

GSK2983559 (compound 3) is a potent, specific and oral active receptor interacting protein 2 (RIP2) kinase inhibitor, which has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.

For research use only. We do not sell to patients.

GSK2983559 Chemical Structure

GSK2983559 Chemical Structure

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
5 mg USD 120 In-stock
Estimated Time of Arrival: December 31
10 mg USD 190 In-stock
Estimated Time of Arrival: December 31
25 mg USD 350 In-stock
Estimated Time of Arrival: December 31
50 mg USD 650 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1050 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of GSK2983559:

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Description

GSK2983559 (compound 3) is a potent, specific and oral active receptor interacting protein 2 (RIP2) kinase inhibitor, which has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples[1].

IC50 & Target

RIP2[1]

Clinical Trial
Molecular Weight

611.61

Formula

C₂₁H₂₈CaN₄O₁₀PS₂

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (ultrasonic;warming;heat to 80°C) (insoluble or slightly soluble)

DMF : < 1 mg/mL (ultrasonic;warming;heat to 80°C) (insoluble)

Ethanol : < 1 mg/mL (ultrasonic) (insoluble)

H2O : < 0.1 mg/mL (ultrasonic) (insoluble)

*GSK2983559 is usually formulated as a suspension.

References
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  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
GSK2983559
Cat. No.:
HY-112038A
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