1. Apoptosis
  2. RIP kinase
  3. GSK2983559

GSK2983559 

Cat. No.: HY-112038A
Handling Instructions

GSK2983559 (compound 3) is a potent, specific and oral bioavailable receptor interacting protein 2 (RIP2) kinase inhibitor, which has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.

For research use only. We do not sell to patients.

GSK2983559 Chemical Structure

GSK2983559 Chemical Structure

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Description

GSK2983559 (compound 3) is a potent, specific and oral bioavailable receptor interacting protein 2 (RIP2) kinase inhibitor, which has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples[1].

IC50 & Target

RIP2[1]

Molecular Weight

611.61

Formula

C₂₁H₂₈CaN₄O₁₀PS₂

SMILES

CC(C)(C)S(C(C(OCCOP(O)([O-])=O)=CC1=NC=N2)=CC1=C2NC3=CC(N=CS4)=C4C=C3)(=O)=O.[H]O[H].[H]O[H].[H]O[H].[Ca+2].[1/2]

Shipping

Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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C1   V1   C2   V2

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Product Name:
GSK2983559
Cat. No.:
HY-112038A
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