1. Apoptosis
  2. RIP kinase
  3. GSK2983559 free acid

GSK2983559 free acid 

Cat. No.: HY-112038 Purity: 99.51%
Handling Instructions

GSK2983559 free acid (compound 3) is a potent, specific and oral bioavailable receptor interacting protein 2 (RIP2) kinase inhibitor. GSK2983559 free acid has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples.

For research use only. We do not sell to patients.

GSK2983559 free acid Chemical Structure

GSK2983559 free acid Chemical Structure

CAS No. : 1579965-12-0

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Free Sample (0.5-1 mg)   Apply now  
5 mg USD 120 In-stock
Estimated Time of Arrival: December 31
10 mg USD 190 In-stock
Estimated Time of Arrival: December 31
25 mg USD 350 In-stock
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50 mg USD 650 In-stock
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100 mg USD 1050 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of GSK2983559 free acid:

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Description

GSK2983559 free acid (compound 3) is a potent, specific and oral bioavailable receptor interacting protein 2 (RIP2) kinase inhibitor. GSK2983559 free acid has excellent activity in blocking many proinflammatory cytokine responses in vivo and in human inflammatory bowel disease explant samples[1].

IC50 & Target

RIP2[1]

Clinical Trial
Molecular Weight

538.53

Formula

C₂₁H₂₃N₄O₇PS₂

CAS No.

1579965-12-0

SMILES

CC(C)(C)S(C(C(OCCOP(O)(O)=O)=CC1=NC=N2)=CC1=C2NC3=CC(N=CS4)=C4C=C3)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (9.28 mM; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8569 mL 9.2845 mL 18.5691 mL
5 mM 0.3714 mL 1.8569 mL 3.7138 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References

Purity: 99.51%

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Keywords:

GSK2983559GSK 2983559GSK-2983559RIP kinaseReceptor-interacting protein kinasesRIPKInhibitorinhibitorinhibit

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Product name:
GSK2983559 free acid
Cat. No.:
HY-112038
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