1. Apoptosis
  2. RIP kinase
  3. GSK840

GSK840 (Synonyms: GSK'840)

Cat. No.: HY-104021 Purity: >98.0%
Handling Instructions

GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 0.9 nM, and inhibits kinase activity with an IC50 of 0.3 nM.

For research use only. We do not sell to patients.

GSK840 Chemical Structure

GSK840 Chemical Structure

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 275 In-stock
Estimated Time of Arrival: December 31
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
10 mg USD 450 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Description

GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 0.9 nM, and inhibits kinase activity with an IC50 of 0.3 nM[1].

IC50 & Target

IC50: 0.3 nM (RIP3)[1]

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References
Molecular Weight

365.43

Formula

C₂₁H₂₃N₃O₃

SMILES

O=C(OC(C)(C)C)CC1=CC=C(N2C3=CC=C(C(NC)=O)C=C3N=C2)C=C1

Shipping

Room temperature in continental US; may vary elsewhere

Purity: >98.0%

  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
GSK840
Cat. No.:
HY-104021
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GSK840

Cat. No.: HY-104021