2361146-30-5
2361146-30-5
Chemical Structure
GSK840
Synonym(s): GSK'840
- CAS No.: 2361146-30-5
- Formula:C21H23N3O3
- Molecular Weight:365.43
IUPAC Name: tert-butyl 2-(4-(5-(methylcarbamoyl)-1H-benzo[d]imidazol-1-yl)phenyl)acetate
InChIKey: UGTLDBJIOSYXRR-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)CC1=CC=C(N2C3=CC=C(C(NC)=O)C=C3N=C2)C=C1
Biological Activity: GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 0.9 nM, and inhibits kinase activity with an IC50 of 0.3 nM[1].
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GSK840 | 99.95% | GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 0.9 nM, and inhibits kinase activity with an IC50 of 0.3 nM. | ||||||||||||||||||||
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GSK840 (Standard) | ≥98% | GSK840 (Standard) is the analytical standard of GSK840 (HY-104021). This product is intended for research and analytical applications. GSK840 (GSK'840) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds RIP3 kinase domain with an IC50 of 0.9 nM, and inhibits kinase activity with an IC50 of 0.3 nM. | ||||||||||||||||||||
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References
Keywords
