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  4. Sodium chloride, for cell culture

Sodium chloride, for cell culture  (Synonyms: Halite, for cell culture)

Cat. No.: HY-Y0344D Purity: 99.9%
COA
SDS
Handling Instructions Technical Support

Sodium chloride, for cell culture is an orally active salt. Sodium chloride, for cell culture induces the expression of ATP1A1. Sodium chloride, for cell culture induces the pro-inflammatory cytokines IL-2, TNFα, IL-9 and several chemokines. Sodium chloride, for cell culture enhances the anti-tumor activities of Digoxin (HY-B1049) against small cell lung cancer. Sodium chloride, for cell culture drives autoimmune disease by the induction of pathogenic Th17 cells.

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Sodium chloride, for cell culture

Sodium chloride, for cell culture 화학구조

CAS No. : 7647-14-5

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100 g 해외재고보유
> 100 g   견적 받기  

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고객리뷰

Based on 3 publication(s) in Google Scholar

Other Forms of Sodium chloride, for cell culture:

Sodium chloride, for cell culture Related Antibodies

Top Publications Citing Use of Products

View All Interleukin Related Isoform Specific Products:

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

  • Biological Activity

  • 순도&문서

  • References

  • 고객리뷰

제품 설명

Sodium chloride, for cell culture is an orally active salt. Sodium chloride, for cell culture induces the expression of ATP1A1. Sodium chloride, for cell culture induces the pro-inflammatory cytokines IL-2, TNFα, IL-9 and several chemokines. Sodium chloride, for cell culture enhances the anti-tumor activities of Digoxin (HY-B1049) against small cell lung cancer. Sodium chloride, for cell culture drives autoimmune disease by the induction of pathogenic Th17 cells[1][2].

IC50 & Target[1][2]

IL-2

 

IL-9

 

In Vitro

Sodium chloride (10-70 mM; 72 h) enhances the anti-tumor activity of Digoxin (HY-B1049) in SCLC cell lines[1].
Sodium chloride (40 mM) specifically promote the generation of a highly pathogenic Th17 cell type[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sodium chloride, for cell culture Related Antibodies
In Vivo

Sodium chloride (3%; p.o. and i.v.; given by drinking water for 6 h before treatment and i.v. with 200 μL 3% NaCl) enhances the anti-tumor activity of Digoxin in mouse model of SCLC[1].
Sodium chloride (1%-4%; p.o.; chow containing 4% NaCl and tap water containing 1% NaCl) induces Th17 cells and exacerbates experimental autoimmune encephalomyelitis in mice[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Small cell lung cancer mice[1]
Dosage: 3%
Administration: p.o. and i.v.; given by drinking water for 6 h before treatment and i.v. with 200 μL 3% NaCl
Result: Did not induce significant tumor growth inhibition.
Reduced tumor volume when combination with Digoxin.
Clinical Trial
분자량

58.44

화학식

NaCl
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[Na]Cl
선적

Room temperature in continental US; may vary elsewhere.
보관

Store at room temperature, keep dry and cool

In solvent -80°C 1 year
-20°C 6 months
용액&용해도
In Vitro: 

H2O : 200 mg/mL (3422.31 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 17.1116 mL 85.5578 mL 171.1157 mL
5 mM 3.4223 mL 17.1116 mL 34.2231 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • 몰농도 계산기

  • 농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
순도&문서

Purity: 99.9%

SDS (393 KB)

COA (252 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 17.1116 mL 85.5578 mL 171.1157 mL 427.7892 mL
5 mM 3.4223 mL 17.1116 mL 34.2231 mL 85.5578 mL
10 mM 1.7112 mL 8.5558 mL 17.1116 mL 42.7789 mL
15 mM 1.1408 mL 5.7039 mL 11.4077 mL 28.5193 mL
20 mM 0.8556 mL 4.2779 mL 8.5558 mL 21.3895 mL
25 mM 0.6845 mL 3.4223 mL 6.8446 mL 17.1116 mL
30 mM 0.5704 mL 2.8519 mL 5.7039 mL 14.2596 mL
40 mM 0.4278 mL 2.1389 mL 4.2779 mL 10.6947 mL
50 mM 0.3422 mL 1.7112 mL 3.4223 mL 8.5558 mL
60 mM 0.2852 mL 1.4260 mL 2.8519 mL 7.1298 mL
80 mM 0.2139 mL 1.0695 mL 2.1389 mL 5.3474 mL
100 mM 0.1711 mL 0.8556 mL 1.7112 mL 4.2779 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Sodium chloride, for cell culture Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sodium chloride, for cell culture7647-14-5Halite, for cell cultureBiochemical Assay ReagentsInterleukin RelatedNa+/K+ ATPaseEnvironmental PollutantsILSodium potassium pumpEnvironmental Contaminantscell cultureInhibitorinhibitorinhibit

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상품명:
Sodium chloride, for cell culture
Cat. No.:
HY-Y0344D
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