Sodium chloride, for cell culture
Based on 3 publication(s) in Google Scholar
Sodium chloride, for cell culture is an orally active salt. Sodium chloride, for cell culture induces the expression of ATP1A1. Sodium chloride, for cell culture induces the pro-inflammatory cytokines IL-2, TNFα, IL-9 and several chemokines. Sodium chloride, for cell culture enhances the anti-tumor activities of Digoxin (HY-B1049) against small cell lung cancer. Sodium chloride, for cell culture drives autoimmune disease by the induction of pathogenic Th17 cells.
For research use only. We do not sell to patients.
- Purity: 99.9%
- CAS No.: 7647-14-5
- Formula: NaCl
- Molecular Weight:58.44
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-Y0537E
Potassium chloride, for cell culture
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HY-D0857
HEPES
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HY-Y1891
Tween 80
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HY-Y0537
Potassium chloride, AR, 99.5%
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HY-Y0873
PEG300
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HY-Y0406E
Calcium chloride anhydrous, for cell culture
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HY-W094475C
Magnesium sulfate heptahydrate, for cell culture
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HY-Y0344I
Sodium chloride, meets analytical specification of Ph. Eur. BP USP, ≤0.00002% Al
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HY-B0389
D-Glucose
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HY-Y0344J
Sodium chloride, for molecular biology
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HY-Y0332K
Potassium dihydrogen phosphate, for cell culture
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HY-D0227F
THAM hydrochloride (≥99%, reagent grade)
Publications Citing Use of MedChemExpress (MCE) Sodium chloride, for cell culture
More
Biological Activity
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IL-2 |
IL-9 |
Sodium chloride (10-70 mM; 72 h) enhances the anti-tumor activity of Digoxin (HY-B1049) in SCLC cell lines[1].
Sodium chloride (40 mM) specifically promote the generation of a highly pathogenic Th17 cell type[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Sodium chloride (1%-4%; p.o.; chow containing 4% NaCl and tap water containing 1% NaCl) induces Th17 cells and exacerbates experimental autoimmune encephalomyelitis in mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Small cell lung cancer mice[1]
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Dosage:3%
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Administration:p.o. and i.v.; given by drinking water for 6 h before treatment and i.v. with 200 μL 3% NaCl
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Result:Did not induce significant tumor growth inhibition.
Reduced tumor volume when combination with Digoxin.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 7647-14-5
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Appearance Solid
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Molecular Weight 58.44
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Formula NaCl
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Color White to off-white
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SMILES
[Na]Cl
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Synonyms
Halite, for cell culture
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Publications (3)
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Journal Impact Factor
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Most Recent
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Nat Microbiol
ATG5 suppresses type I IFN-dependent neutrophil effector functions during Mycobacterium tuberculosis infection in mice. [Abstract]2025 Jun;10(6):1323-1339. PMID: 40374743 -
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Biochem Pharmacol
The C-terminal region regulates the constitutive signaling activity of GPR119: G protein recruitment. [Abstract]2025 Nov:241:117095. PMID: 40617490
Solvent & Solubility
H2O : 200 mg/mL (3422.31 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Deng K, et al. Sodium chloride (NaCl) potentiates digoxin-induced anti-tumor activity in small cell lung cancer. Cancer Biol Ther. 2019;20(1):52-64. [Content Brief]
[2]. Kleinewietfeld M, et al. Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature. 2013 Apr 25;496(7446):518-22. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 17.1116 mL | 85.5578 mL | 171.1157 mL | 427.7892 mL |
| 5 mM | 3.4223 mL | 17.1116 mL | 34.2231 mL | 85.5578 mL | |
| 10 mM | 1.7112 mL | 8.5558 mL | 17.1116 mL | 42.7789 mL | |
| 15 mM | 1.1408 mL | 5.7039 mL | 11.4077 mL | 28.5193 mL | |
| 20 mM | 0.8556 mL | 4.2779 mL | 8.5558 mL | 21.3895 mL | |
| 25 mM | 0.6845 mL | 3.4223 mL | 6.8446 mL | 17.1116 mL | |
| 30 mM | 0.5704 mL | 2.8519 mL | 5.7039 mL | 14.2596 mL | |
| 40 mM | 0.4278 mL | 2.1389 mL | 4.2779 mL | 10.6947 mL | |
| 50 mM | 0.3422 mL | 1.7112 mL | 3.4223 mL | 8.5558 mL | |
| 60 mM | 0.2852 mL | 1.4260 mL | 2.8519 mL | 7.1298 mL | |
| 80 mM | 0.2139 mL | 1.0695 mL | 2.1389 mL | 5.3474 mL | |
| 100 mM | 0.1711 mL | 0.8556 mL | 1.7112 mL | 4.2779 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Sodium chloride, for cell culture Related Classifications
HY-Y0344D Related Classifications
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