Potassium chloride, for cell culture
Based on 1 publication(s) in Google Scholar
Potassium chloride, for cell culture is potassium chloride that can be used for cell culture. Potassium chloride, for cell culture increases extracellular potassium ion concentration to induce cellular depolarization, thereby activating voltage-gated calcium channels and regulating intracellular calcium signaling. Potassium chloride, for cell culture upregulates Brn-5. Potassium chloride, for cell culture inhibits the proliferation of neurons and some plant cells.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 7447-40-7
- Formula: KCl
- Molecular Weight:74.55
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Storage:
RT, sealed storage, away from moisture and light.
In solvent -80°C, 1 year , -20°C, 6 months
Publications Citing Use of MedChemExpress (MCE) Potassium chloride, for cell culture
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
174 mM
Compound: 4873
|
Substrate uptake by the Sodium/Potassium/Calcium Exchanger 4 (NCKX4, SLC24A4) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A4 cells (PubChem AID: 1794814)
Substrate uptake by the Sodium/Potassium/Calcium Exchanger 4 (NCKX4, SLC24A4) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A4 cells (PubChem AID: 1794814)
|
10.5281/zenodo.7360317 |
| HEK293 | EC50 |
280 mM
Compound: 4873
|
Substrate uptake by the Sodium/Potassium/Calcium Exchanger 2 (NCKX2, SLC24A2) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A2 cells (PubChem AID: 1794815)
Substrate uptake by the Sodium/Potassium/Calcium Exchanger 2 (NCKX2, SLC24A2) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A2 cells (PubChem AID: 1794815)
|
10.5281/zenodo.7360329 |
Potassium chloride, for cell culture (25-50 mM; 24-48 h) inhibits the proliferation of cerebellar granule neuron progenitors and antagonizes the mitogenic response to IGF-I in cultured cells, while allowing cultured granule cells to continue to differentiate[1].
Potassium chloride, for cell culture (50-800 mM; 12-72 h) inhibits the growth of Ginkgo biloba cell suspensions[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Cerebellar granule neuron progenitors
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Concentration:5 mM (control), 25 mM, 50 mM
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Incubation Time:24, 48 h
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Result:Upregulated Brn-5 expression (a differentiation marker), with higher expression at 48 h.
Chemical Information
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CAS No. 7447-40-7
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Appearance Solid
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Molecular Weight 74.55
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Formula KCl
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Color White to light yellow
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SMILES
[K]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, sealed storage, away from moisture and light
In solvent -80°C 1 year -20°C 6 months
Publications (1)
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Journal Impact Factor
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Most Recent
Solvent & Solubility
H2O : 100 mg/mL (1341.38 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 13.4138 mL | 67.0691 mL | 134.1382 mL | 335.3454 mL |
| 5 mM | 2.6828 mL | 13.4138 mL | 26.8276 mL | 67.0691 mL | |
| 10 mM | 1.3414 mL | 6.7069 mL | 13.4138 mL | 33.5345 mL | |
| 15 mM | 0.8943 mL | 4.4713 mL | 8.9425 mL | 22.3564 mL | |
| 20 mM | 0.6707 mL | 3.3535 mL | 6.7069 mL | 16.7673 mL | |
| 25 mM | 0.5366 mL | 2.6828 mL | 5.3655 mL | 13.4138 mL | |
| 30 mM | 0.4471 mL | 2.2356 mL | 4.4713 mL | 11.1782 mL | |
| 40 mM | 0.3353 mL | 1.6767 mL | 3.3535 mL | 8.3836 mL | |
| 50 mM | 0.2683 mL | 1.3414 mL | 2.6828 mL | 6.7069 mL | |
| 60 mM | 0.2236 mL | 1.1178 mL | 2.2356 mL | 5.5891 mL | |
| 80 mM | 0.1677 mL | 0.8384 mL | 1.6767 mL | 4.1918 mL | |
| 100 mM | 0.1341 mL | 0.6707 mL | 1.3414 mL | 3.3535 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.