Potassium chloride, for molecular biology

Name: Potassium chloride, for molecular biology
Brand: MedChemExpress
SKU: HY-Y0537B
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Cat. No.: HY-Y0537B Purity: 99.50%: Data Sheet
COA

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Handling Instructions
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Potassium chloride, for molecular biology is potassium chloride that can be used in molecular biology. Potassium chloride, for molecular biology affects the stability of biological membranes by disrupting the electrostatic interactions between proteins and lipids. Potassium chloride, for molecular biology affects the solubility of myofibrillar proteins and the integrity of mitochondria. Potassium chloride, for molecular biology is commonly used in homogenization buffers and protein extraction procedures.

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Potassium chloride, for molecular biology 화학구조

CAS No. : 7447-40-7

사이즈	재고	수량
5 g	해외재고보유	Estimated Time of Arrival: December 31
25 g	해외재고보유	Estimated Time of Arrival: December 31
50 g	해외재고보유	Estimated Time of Arrival: December 31
100 g	해외재고보유	Estimated Time of Arrival: December 31
> 100 g	견적 받기

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고객리뷰

Based on 1 Customer Validation

Other Forms of Potassium chloride, for molecular biology:

Potassium chloride, AR, 99.5% In-stock

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•Related Small Molecules:

•Related Proteins:

Biological Activity
순도&문서
References
고객리뷰

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	174 mM Compound: 4873	Substrate uptake by the Sodium/Potassium/Calcium Exchanger 4 (NCKX4, SLC24A4) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A4 cells (PubChem AID: 1794814) Substrate uptake by the Sodium/Potassium/Calcium Exchanger 4 (NCKX4, SLC24A4) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A4 cells (PubChem AID: 1794814)	10.5281/zenodo.7360317
HEK293	EC₅₀	280 mM Compound: 4873	Substrate uptake by the Sodium/Potassium/Calcium Exchanger 2 (NCKX2, SLC24A2) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A2 cells (PubChem AID: 1794815) Substrate uptake by the Sodium/Potassium/Calcium Exchanger 2 (NCKX2, SLC24A2) as assessed by Screen Questtrade mark Fluo-8 NW calcium assay kit in HEK-293 JumpIN-SLC24A2 cells (PubChem AID: 1794815)	10.5281/zenodo.7360329

In Vitro

Potassium chloride, for molecular biology (25-200 mM) causes mitochondrial membrane rupture, cristae deformation, and release of membrane-bound and matrix enzymes, disrupting mitochondrial integrity in isolated mouse liver mitochondria^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

74.55

화학식

KCl

CAS No.

7447-40-7

Appearance

Solid

Color

White to off-white

SMILES

[K]Cl

선적

Room temperature in continental US; may vary elsewhere.

보관

Store at room temperature, keep dry and cool

In solvent	-80°C	1 year
	-20°C	6 months

용액&용해도

In Vitro:

H₂O : ≥ 200 mg/mL (2682.76 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	13.4138 mL	67.0691 mL	134.1382 mL
5 mM	2.6828 mL	13.4138 mL	26.8276 mL
10 mM	1.3414 mL	6.7069 mL	13.4138 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.50%

Select Batch:

Data Sheet (280 KB) SDS (393 KB)

COA (257 KB)

Handling Instructions (2659 KB)

References

[1]. Dyer PN, et al. Reconstitution of nucleosome core particles from recombinant histones and DNA. Methods Enzymol. 2004;375:23-44. [Content Brief]

[2]. Thisse C, et al. High-resolution in situ hybridization to whole-mount zebrafish embryos. Nat Protoc. 2008;3(1):59-69. [Content Brief]

[3]. Solari E, et al. Fluid Osmolarity Acutely and Differentially Modulates Lymphatic Vessels Intrinsic Contractions and Lymph Flow. Front Physiol. 2018 Jul 5;9:871. [Content Brief]

[4]. Mishra S, et al. Molecular Integrity of Mitochondria Alters by Potassium Chloride. Int J Proteomics. 2015;2015:647408. [Content Brief]

[5]. Jiao X, et al. Solubilization of fish myofibrillar proteins in NaCl and KCl solutions: A DIA-based proteomics analysis. Food Chem. 2024 Jul 1;445:138662. [Content Brief]

[6]. Coulibaly B, et al. Lethal injection of potassium chloride: first description of the pathological appearance of organs. J Appl Toxicol. 2010 May;30(4):378-80. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	13.4138 mL	67.0691 mL	134.1382 mL	335.3454 mL
	5 mM	2.6828 mL	13.4138 mL	26.8276 mL	67.0691 mL
	10 mM	1.3414 mL	6.7069 mL	13.4138 mL	33.5345 mL
	15 mM	0.8943 mL	4.4713 mL	8.9425 mL	22.3564 mL
	20 mM	0.6707 mL	3.3535 mL	6.7069 mL	16.7673 mL
	25 mM	0.5366 mL	2.6828 mL	5.3655 mL	13.4138 mL
	30 mM	0.4471 mL	2.2356 mL	4.4713 mL	11.1782 mL
	40 mM	0.3353 mL	1.6767 mL	3.3535 mL	8.3836 mL
	50 mM	0.2683 mL	1.3414 mL	2.6828 mL	6.7069 mL
	60 mM	0.2236 mL	1.1178 mL	2.2356 mL	5.5891 mL
	80 mM	0.1677 mL	0.8384 mL	1.6767 mL	4.1918 mL
	100 mM	0.1341 mL	0.6707 mL	1.3414 mL	3.3535 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.