1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite

Oleic acid (Synonyms: 9-cis-Octadecenoic acid; 9Z-Octadecenoic acid)

Cat. No.: HY-N1446 Purity: >98.0%
Handling Instructions

Oleic acid is an abundant monounsaturated fatty acid.

For research use only. We do not sell to patients.

Oleic acid Chemical Structure

Oleic acid Chemical Structure

CAS No. : 112-80-1

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  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Oleic acid is an abundant monounsaturated fatty acid.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Oleic acid is the most common monounsaturated fatty acids (FA) in human adipocytes and other tissues. Oleic acid prompts cell proliferation and migration in high metastatic cancer cells via enhancing β-oxidation mediated by AMPK activation. Oleic acid inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines[1].

Clinical Trial
Solvent & Solubility
In Vitro: 

DMSO : ≥ 62.5 mg/mL (221.27 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5403 mL 17.7016 mL 35.4032 mL
5 mM 0.7081 mL 3.5403 mL 7.0806 mL
10 mM 0.3540 mL 1.7702 mL 3.5403 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (7.36 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (7.36 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (7.36 mM); Clear solution

References
Molecular Weight

282.46

Formula

C₁₈H₃₄O₂

CAS No.

112-80-1

SMILES

CCCCCCCC/C=C\CCCCCCCC(O)=O

Storage
Pure form -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Oleic acid
Cat. No.:
HY-N1446
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Oleic acid

Cat. No.: HY-N1446