- Oligonucleotides
- Phosphoramidites
- Cytosine
Cytosine
-
Cytosine (118)
- Formula: C46H51FN5O8P
- Molecular Weight: 851.90
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
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- Formula: C49H56N5O9P
- Molecular Weight: 889.97
5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is a potent nucleic acid analog. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite blongs to modified antisense oligonucleotide. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite allows the formation of a specific conformation of the furanose ring of the oligonucleotide through the introduction of a cEt modification, enhancing the ability to hybridize to complementary RNA. 5'-ODMT cEt N-Bzm5 C Phosphoramidite Amidite is mainly used in the research of regulation of gene expression related to metabolic diseases, cardiovascular diseases, cancers and the development of antisense compounds.
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- Formula: C41H50N5O8P
- Molecular Weight: 771.84
DMT-dC(ac) Phosphoramidite (compound 30f) is a phosphoramidite derivative that can be used for the oligonucleotide synthesis.
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- Formula: C37H35N3O8
- Molecular Weight: 649.69
5'-O-DMT-Bz-Rc is a modified nucleoside and can be used to synthesize DNA or RNA.
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- Formula: C42H52N5O9P
- Molecular Weight: 801.86
2'-OMe-Ac-C Phosphoramidite is a modified phosphoramidite and can be used for the oligonucleotide synthesis. 2'-OMe-Ac-C Phosphoramidite contributes to improving the stability and activity of oligonucleotides.
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- Formula: C41H49FN5O8P
- Molecular Weight: 789.83
Dmt-2'-f-dc(ac) amidite (2'-F-Ac-dC Phosphoramidite) is a phosphoramidite which can be used in the preparation of cyclic purine dinucleotides.
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- Formula: C32H33N3O7
- Molecular Weight: 571.62
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7), a deoxynucleoside, can be used to synthesize of dodecyl phosphoramidite which is the raw material for dod‐DNA (amphiphilic DNA containing an internal hydrophobic region consisting of dodecyl phosphotriester linkages) synthesis.
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- Formula: C38H37N3O8
- Molecular Weight: 663.72
DMT-2'-OMe-Bz-C is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
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- Formula: C49H58N5O10P
- Molecular Weight: 907.99
2'-O-MOE-rC is a 2'-O-MOE modified nucleoside. 2'-O-MOE-rC can be used for synthesis of DNA.
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- Formula: C47H54N5O8P
- Molecular Weight: 847.93
DMT-5Me-dC(Bz)-CE Phosphoramidite is a chemical structural unit that can be used in solid-phase DNA synthesis. DMT-5Me-dC(Bz)-CE Phosphoramidite can introduce the 5-methylcytidine base into the DNA chain to enhance its stability and binding affinity. DMT-5Me-dC(Bz)-CE Phosphoramidite can be used to construct modified oligonucleotides, especially for constructing locked nucleic acids (LNA) .
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- Formula: C37H34FN3O7
- Molecular Weight: 651.68
5'-O-DMT-N4-Bz-2'-F-dC is a nucleoside with protective and modification effects.
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- Formula: C46H52N5O8P
- Molecular Weight: 833.91
DMT-dC (bz) Phosphoramidite is a protected deoxycytidine phosphoramidite monomer, as well as a building block for mechanochemical DNA synthesis. DMT-dC (bz) Phosphoramidite serves as a reagent for oligonucleotide synthesis.
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- Formula: C63H94N5O9P
- Molecular Weight: 1096.42
DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite is an RNA phosphoramidite monomer. DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite enables site-specific introduction of 2'-O-C22 lipophilic modification at cytidine positions during oligonucleotide synthesis, which is used to construct double-stranded RNA (dsRNA) molecules with extrahepatic delivery capability. DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite supports target gene silencing in skeletal muscle, cardiac muscle and adipose tissue by enhancing the lipophilicity and tissue uptake efficiency of dsRNA. Construction and mechanism study of DMTr-2'-O-C22-rC (Ac)-3'-CE-Phosphoramidite nucleic acid silencing molecules.
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- Formula: C39H47FN5O7P
- Molecular Weight: 747.79
DMTr-5-fluoro-2'-deoxycytidine-phosphoramidite (compound 1B) is a phosphoramidite of 5-Fluoro-2'-deoxycytidine.
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- Formula: C48H56N5O9P
- Molecular Weight: 877.96
5-Me-DMT-2'-O-Me-C(Bz)-CE-Phosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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- Formula: C42H52N5O8P
- Molecular Weight: 785.86
5-Me-dC(Ac) amidite is an acetyl (Ac)-modified nucleotide commonly used in the synthesis of modified oligonucleotides.
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- Formula: C38H37N3O7
- Molecular Weight: 647.72
5'-O-DMT-N4-Bz-5-Me-dC is a modified nucleoside. 5'-O-DMT-2'-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.
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- Formula: C38H47N3O8Si
- Molecular Weight: 701.88
5'-O-DMT-3'-O-TBDMS-Ac-rC is a modified nucleoside and can be used to synthesize DNA or RNA.
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- Formula: C32H32FN3O7
- Molecular Weight: 589.61
5'-O-DMT-N4-Ac-2'-F-dC is a modified nucleotide commonly used in the synthesis of modified oligonucleotides.
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- Formula: C47H54N5O9P
- Molecular Weight: 863.93
2'-O-Me-C(Bz) Phosphoramidite is a modified phosphoramidite monomer, which can be used for the oligonucleotide synthesis.
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