2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
Based on 1 Customer Validation
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
For research use only. We do not sell to patients.
- Purity : 99.84%
- CAS No.: 1404463-12-2
- Formula: C46H51FN5O8P
- Molecular Weight:851.90
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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HY-45492
DMT-2'Fluoro-DG(IB) Amidite -
HY-W101391
DMT-2'O-Methyl-rU Phosphoramidite -
HY-104014
DMT-2'O-MOE-rG(ib) Phosphoramidite -
HY-138578
2'-O-Me-C(Bz) Phosphoramidite -
HY-45491
Dmt-2'-f-dc(ac) amidite -
HY-138580
2'-OMe-A(Bz) Phosphoramidite -
HY-21997
DMT-2'fluoro-da(bz) amidite -
HY-W570885
2'-O-MOE-rC -
HY-154409
2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite -
HY-45409
DMT-2′Fluoro-dU Phosphoramidite -
HY-W570890
2'-O-MOE-5-Me-C(Bz) -
HY-138579
2'-OMe-G(ibu) Phosphoramidite
Biological Activity
Description
Chemical Information
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CAS No. 1404463-12-2
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Appearance Solid
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Molecular Weight 851.90
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Formula C46H51FN5O8P
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Color White to off-white
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SMILES
O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]3F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 125 mg/mL (146.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1738 mL | 5.8692 mL | 11.7385 mL | 29.3462 mL |
| 5 mM | 0.2348 mL | 1.1738 mL | 2.3477 mL | 5.8692 mL | |
| 10 mM | 0.1174 mL | 0.5869 mL | 1.1738 mL | 2.9346 mL | |
| 15 mM | 0.0783 mL | 0.3913 mL | 0.7826 mL | 1.9564 mL | |
| 20 mM | 0.0587 mL | 0.2935 mL | 0.5869 mL | 1.4673 mL | |
| 25 mM | 0.0470 mL | 0.2348 mL | 0.4695 mL | 1.1738 mL | |
| 30 mM | 0.0391 mL | 0.1956 mL | 0.3913 mL | 0.9782 mL | |
| 40 mM | 0.0293 mL | 0.1467 mL | 0.2935 mL | 0.7337 mL | |
| 50 mM | 0.0235 mL | 0.1174 mL | 0.2348 mL | 0.5869 mL | |
| 60 mM | 0.0196 mL | 0.0978 mL | 0.1956 mL | 0.4891 mL | |
| 80 mM | 0.0147 mL | 0.0734 mL | 0.1467 mL | 0.3668 mL | |
| 100 mM | 0.0117 mL | 0.0587 mL | 0.1174 mL | 0.2935 mL |
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite Related Classifications
HY-154414 Related Classifications
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