2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite

Cat. No.: HY-154414 Pureza: 99.84%: Ficha de datos
COA

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2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.

Para uso exclusivo en investigación. No vendemos a pacientes.

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite Estructura química

No. CAS : 1404463-12-2

Tamaño	Stock	Cantidad
Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
Muestra gratis (0.1 - 0.2 mg)	Solicite ahora
5 mg	En stock	Estimated Time of Arrival: December 31
10 mg	En stock	Estimated Time of Arrival: December 31
25 mg	En stock	Estimated Time of Arrival: December 31
50 mg	En stock	Estimated Time of Arrival: December 31
100 mg	En stock	Estimated Time of Arrival: December 31
250 mg	En stock	Estimated Time of Arrival: December 31
500 mg	Obtener un presupuesto
1 g	Obtener un presupuesto

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Actividad biológica
Pureza y Documentación
Referencias
Revisión del cliente

Descripciòn

Peso molecular

851.90

Fòrmula

C₄₆H₅₁FN₅O₈P

No. CAS

1404463-12-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]3F

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvente y solubilidad

In Vitro:

DMSO : 125 mg/mL (146.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1738 mL	5.8692 mL	11.7385 mL
5 mM	0.2348 mL	1.1738 mL	2.3477 mL
10 mM	0.1174 mL	0.5869 mL	1.1738 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Calculadora de molaridad
Calculadora de dilución

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Pureza y Documentación

Purity: 99.84%

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Ficha de datos (278 KB) SDS (393 KB)

COA (264 KB) HNMR (303 KB) RP-HPLC (86 KB)

Instrucciones de manejo (2659 KB)

Referencias

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1738 mL	5.8692 mL	11.7385 mL	29.3462 mL
	5 mM	0.2348 mL	1.1738 mL	2.3477 mL	5.8692 mL
	10 mM	0.1174 mL	0.5869 mL	1.1738 mL	2.9346 mL
	15 mM	0.0783 mL	0.3913 mL	0.7826 mL	1.9564 mL
	20 mM	0.0587 mL	0.2935 mL	0.5869 mL	1.4673 mL
	25 mM	0.0470 mL	0.2348 mL	0.4695 mL	1.1738 mL
	30 mM	0.0391 mL	0.1956 mL	0.3913 mL	0.9782 mL
	40 mM	0.0293 mL	0.1467 mL	0.2935 mL	0.7337 mL
	50 mM	0.0235 mL	0.1174 mL	0.2348 mL	0.5869 mL
	60 mM	0.0196 mL	0.0978 mL	0.1956 mL	0.4891 mL
	80 mM	0.0147 mL	0.0734 mL	0.1467 mL	0.3668 mL
	100 mM	0.0117 mL	0.0587 mL	0.1174 mL	0.2935 mL