2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite

製品番号: HY-154414 純度: 99.84%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite 構造式

CAS 番号 : 1404463-12-2

容量	価格（税別）	在庫状況	数量
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
>無料サンプル (0.1 - 0.2 mg)		今すぐ申し込む
5 mg	$40	在庫あり	Estimated Time of Arrival: December 31
10 mg	$60	在庫あり	Estimated Time of Arrival: December 31
25 mg	$120	在庫あり	Estimated Time of Arrival: December 31
50 mg	$185	在庫あり	Estimated Time of Arrival: December 31
100 mg	$300	在庫あり	Estimated Time of Arrival: December 31
250 mg	$520	在庫あり	Estimated Time of Arrival: December 31
500 mg		お問い合わせ
1 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
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製品説明

分子量

851.90

分子式

C₄₆H₅₁FN₅O₈P

CAS 番号

1404463-12-2

Appearance

Solid

Color

White to off-white

SMILES

O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]3F

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶剤 & 溶解度

体外:

DMSO : 125 mg/mL (146.73 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.1738 mL	5.8692 mL	11.7385 mL
5 mM	0.2348 mL	1.1738 mL	2.3477 mL
10 mM	0.1174 mL	0.5869 mL	1.1738 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 99.84%

Select Batch:

データシート (278 KB) SDS (393 KB)

COA (264 KB) HNMR (303 KB) RP-HPLC (86 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.1738 mL	5.8692 mL	11.7385 mL	29.3462 mL
	5 mM	0.2348 mL	1.1738 mL	2.3477 mL	5.8692 mL
	10 mM	0.1174 mL	0.5869 mL	1.1738 mL	2.9346 mL
	15 mM	0.0783 mL	0.3913 mL	0.7826 mL	1.9564 mL
	20 mM	0.0587 mL	0.2935 mL	0.5869 mL	1.4673 mL
	25 mM	0.0470 mL	0.2348 mL	0.4695 mL	1.1738 mL
	30 mM	0.0391 mL	0.1956 mL	0.3913 mL	0.9782 mL
	40 mM	0.0293 mL	0.1467 mL	0.2935 mL	0.7337 mL
	50 mM	0.0235 mL	0.1174 mL	0.2348 mL	0.5869 mL
	60 mM	0.0196 mL	0.0978 mL	0.1956 mL	0.4891 mL
	80 mM	0.0147 mL	0.0734 mL	0.1467 mL	0.3668 mL
	100 mM	0.0117 mL	0.0587 mL	0.1174 mL	0.2935 mL