1404463-12-2

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite Chemical Structure
1404463-12-2

Chemical Structure

2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite

  • CAS. Nr.: 1404463-12-2
  • Formula:C46H51FN5O8P
  • Molecular Weight:851.90

IUPAC Name: (2R,3R,4S,5R)-5-(4-benzamido-2-oxopyrimidin-1(2H)-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChIKey: CKKJPMGSTGVCJJ-OEJVQKCDSA-N

SMILES: O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@@H]3O[C@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]3F

Biological Activity: 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

Art. -Nr. Produktname Reinheit Beschreibung Pricing
HY-154414
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite 99.84% 2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite is a cytidine analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities.
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