2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite

2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite 

Cat. No.: HY-154409 Purity: 99.16%
COA Handling Instructions

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2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

For research use only. We do not sell to patients.

2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite Chemical Structure

2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite Chemical Structure

CAS No. : 329187-86-2

Size Price Stock Quantity
1 mg USD 55 In-stock
5 mg USD 110 In-stock
10 mg   Get quote  
50 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite Related Antibodies

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  • Purity & Documentation

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Description

2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Molecular Weight

875.92

Formula

C47H51FN7O7P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CC=C1)NC2=NC=NC3=C2N=CN3[C@@H]4O[C@H](COC(C5=CC=C(OC)C=C5)(C6=CC=CC=C6)C7=CC=C(OC)C=C7)[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H]4F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (114.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1417 mL 5.7083 mL 11.4166 mL
5 mM 0.2283 mL 1.1417 mL 2.2833 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1417 mL 5.7083 mL 11.4166 mL 28.5414 mL
5 mM 0.2283 mL 1.1417 mL 2.2833 mL 5.7083 mL
10 mM 0.1142 mL 0.5708 mL 1.1417 mL 2.8541 mL
15 mM 0.0761 mL 0.3806 mL 0.7611 mL 1.9028 mL
20 mM 0.0571 mL 0.2854 mL 0.5708 mL 1.4271 mL
25 mM 0.0457 mL 0.2283 mL 0.4567 mL 1.1417 mL
30 mM 0.0381 mL 0.1903 mL 0.3806 mL 0.9514 mL
40 mM 0.0285 mL 0.1427 mL 0.2854 mL 0.7135 mL
50 mM 0.0228 mL 0.1142 mL 0.2283 mL 0.5708 mL
60 mM 0.0190 mL 0.0951 mL 0.1903 mL 0.4757 mL
80 mM 0.0143 mL 0.0714 mL 0.1427 mL 0.3568 mL
100 mM 0.0114 mL 0.0571 mL 0.1142 mL 0.2854 mL
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2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite329187-86-2Nucleoside Antimetabolite/Analogmuscle vasodilatorInhibitorinhibitorinhibit

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