DMT-2'O-MOE-rG(ib) Phosphoramidite

Cat. No.: HY-104014 Purity: 95.01%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DMT-2'O-MOE-rG(ib) Phosphoramidite (1g), belonging to the amide family of trivalent phosphate H3PO3, is a derivative of nucleotides and guanosine and can be used in the stereochemical synthesis of phosphorothioate oligonucleotides.

For research use only. We do not sell to patients.

DMT-2'O-MOE-rG(ib) Phosphoramidite Chemical Structure

CAS No. : 251647-55-9

Size	Price	Stock	Quantity
Free Sample (0.1 - 0.5 mg)		Apply Now
250 mg	USD 57	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 63	In-stock	Estimated Time of Arrival: December 31
1 g	USD 69	In-stock	Estimated Time of Arrival: December 31
5 g		Get quote
10 g		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

913.99

Formula

C₄₇H₆₀N₇O₁₀P

CAS No.

251647-55-9

Appearance

Solid

Color

White to off-white

SMILES

COCCO[C@@H]1[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=NC6=C5N=C(NC6=O)NC(C(C)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (273.53 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.0941 mL	5.4705 mL	10.9410 mL
5 mM	0.2188 mL	1.0941 mL	2.1882 mL
10 mM	0.1094 mL	0.5471 mL	1.0941 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 95.01%

Select Batch:

Data Sheet (278 KB) SDS (393 KB)

COA (264 KB) HNMR (327 KB) RP-HPLC (205 KB) MS (184 KB)

Handling Instructions (2659 KB)

References

[1]. Vasulinga T, et al. Stereoselective Synthesis of Alkylphosphonates: A Facile Rearrangement of Cyanoethyl-Protected Nucleoside Phosphoramidites. Org. Proc. Res. Dev. 2004, 8, 4, 603–608

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.0941 mL	5.4705 mL	10.9410 mL	27.3526 mL
	5 mM	0.2188 mL	1.0941 mL	2.1882 mL	5.4705 mL
	10 mM	0.1094 mL	0.5471 mL	1.0941 mL	2.7353 mL
	15 mM	0.0729 mL	0.3647 mL	0.7294 mL	1.8235 mL
	20 mM	0.0547 mL	0.2735 mL	0.5471 mL	1.3676 mL
	25 mM	0.0438 mL	0.2188 mL	0.4376 mL	1.0941 mL
	30 mM	0.0365 mL	0.1824 mL	0.3647 mL	0.9118 mL
	40 mM	0.0274 mL	0.1368 mL	0.2735 mL	0.6838 mL
	50 mM	0.0219 mL	0.1094 mL	0.2188 mL	0.5471 mL
	60 mM	0.0182 mL	0.0912 mL	0.1824 mL	0.4559 mL
	80 mM	0.0137 mL	0.0684 mL	0.1368 mL	0.3419 mL
	100 mM	0.0109 mL	0.0547 mL	0.1094 mL	0.2735 mL