DMT-2'O-MOE-rG(ib) Phosphoramidite
Based on 1 Customer Validation
DMT-2'O-MOE-rG(ib) Phosphoramidite belongs to cyanoethyl-protected nucleoside phosphoramidites. DMT-2'O-MOE-rG(ib) Phosphoramidite is a derivative of nucleotide and guanosine. DMT-2'O-MOE-rG(ib) Phosphoramidite can be used for the stereochemical synthesis of phosphorothioate oligonucleotides.
For research use only. We do not sell to patients.
- Purity: 95.01%
- CAS No.: 251647-55-9
- Formula: C47H60N7O10P
- Molecular Weight:913.99
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
All DNA/RNA Synthesis Isoforms
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Biological Activity
DMT-2'O-MOE-rG(ib) Phosphoramidite (Compound 1g) can undergo a rearrangement reaction to form cyanoethyl phosphonate under the action of acrylonitrile[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 251647-55-9
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Appearance Solid
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Molecular Weight 913.99
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Formula C47H60N7O10P
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Color White to off-white
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SMILES
COCCO[C@@H]1[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)O[C@H]1N5C=NC6=C5N=C(NC6=O)NC(C(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 200 mg/mL (218.82 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (280 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0941 mL | 5.4705 mL | 10.9410 mL | 27.3526 mL |
| 5 mM | 0.2188 mL | 1.0941 mL | 2.1882 mL | 5.4705 mL | |
| 10 mM | 0.1094 mL | 0.5471 mL | 1.0941 mL | 2.7353 mL | |
| 15 mM | 0.0729 mL | 0.3647 mL | 0.7294 mL | 1.8235 mL | |
| 20 mM | 0.0547 mL | 0.2735 mL | 0.5471 mL | 1.3676 mL | |
| 25 mM | 0.0438 mL | 0.2188 mL | 0.4376 mL | 1.0941 mL | |
| 30 mM | 0.0365 mL | 0.1824 mL | 0.3647 mL | 0.9118 mL | |
| 40 mM | 0.0274 mL | 0.1368 mL | 0.2735 mL | 0.6838 mL | |
| 50 mM | 0.0219 mL | 0.1094 mL | 0.2188 mL | 0.5471 mL | |
| 60 mM | 0.0182 mL | 0.0912 mL | 0.1824 mL | 0.4559 mL | |
| 80 mM | 0.0137 mL | 0.0684 mL | 0.1368 mL | 0.3419 mL | |
| 100 mM | 0.0109 mL | 0.0547 mL | 0.1094 mL | 0.2735 mL |