DMT-2'-O-MOE-rA(Bz) phosphoramidite
Based on 1 Customer Validation
DMT-2'-O-MOE-rA(Bz) phosphoramidite is an adenine nucleoside analog. DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used in research on oligonucleotide synthesis.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 251647-53-7
- Formula: C50H58N7O9P
- Molecular Weight:932.01
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
In oligonucleotide synthesis, DMT-2'-O-MOE-rA(Bz) phosphoramidite can be used to introduce 2'-O-methoxyethyl-modified adenine into oligonucleotide chains. This modification can enhance the double-strand stability of oligonucleotides, improve their resistance to nucleases, and exhibit relatively low toxicity.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 251647-53-7
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Appearance Solid
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Molecular Weight 932.01
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Formula C50H58N7O9P
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Color White to off-white
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SMILES
O=C(C1=CC=CC=C1)NC2=NC=NC3=C2N=CN3[C@H]4[C@H](OCCOC)[C@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](COC(C5=CC=C(OC)C=C5)(C6=CC=CC=C6)C7=CC=C(OC)C=C7)O4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : 200 mg/mL (214.59 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0729 mL | 5.3647 mL | 10.7295 mL | 26.8237 mL |
| 5 mM | 0.2146 mL | 1.0729 mL | 2.1459 mL | 5.3647 mL | |
| 10 mM | 0.1073 mL | 0.5365 mL | 1.0729 mL | 2.6824 mL | |
| 15 mM | 0.0715 mL | 0.3576 mL | 0.7153 mL | 1.7882 mL | |
| 20 mM | 0.0536 mL | 0.2682 mL | 0.5365 mL | 1.3412 mL | |
| 25 mM | 0.0429 mL | 0.2146 mL | 0.4292 mL | 1.0729 mL | |
| 30 mM | 0.0358 mL | 0.1788 mL | 0.3576 mL | 0.8941 mL | |
| 40 mM | 0.0268 mL | 0.1341 mL | 0.2682 mL | 0.6706 mL | |
| 50 mM | 0.0215 mL | 0.1073 mL | 0.2146 mL | 0.5365 mL | |
| 60 mM | 0.0179 mL | 0.0894 mL | 0.1788 mL | 0.4471 mL | |
| 80 mM | 0.0134 mL | 0.0671 mL | 0.1341 mL | 0.3353 mL | |
| 100 mM | 0.0107 mL | 0.0536 mL | 0.1073 mL | 0.2682 mL |