2. Cell Cycle/DNA Damage
  3. DNA/RNA Synthesis
  4. DMT-5Me-dC(Bz)-CE Phosphoramidite

DMT-5Me-dC(Bz)-CE Phosphoramidite 

Cat. No.: HY-46317 Purity: 98.36%
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DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding.

For research use only. We do not sell to patients.

DMT-5Me-dC(Bz)-CE Phosphoramidite Chemical Structure

DMT-5Me-dC(Bz)-CE Phosphoramidite Chemical Structure

CAS No. : 105931-57-5

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Based on 1 publication(s) in Google Scholar

DMT-5Me-dC(Bz)-CE Phosphoramidite Related Antibodies

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Description

DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding[1].

Molecular Weight

847.93

Formula

C47H54N5O8P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)N(C(C)C)P(OCCC#N)O[C@@H](C[C@@](N1C(N=C(C(C)=C1)NC(C2=CC=CC=C2)=O)=O)([H])O3)[C@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (294.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1793 mL 5.8967 mL 11.7934 mL
5 mM 0.2359 mL 1.1793 mL 2.3587 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.1793 mL 5.8967 mL 11.7934 mL 29.4836 mL
5 mM 0.2359 mL 1.1793 mL 2.3587 mL 5.8967 mL
10 mM 0.1179 mL 0.5897 mL 1.1793 mL 2.9484 mL
15 mM 0.0786 mL 0.3931 mL 0.7862 mL 1.9656 mL
20 mM 0.0590 mL 0.2948 mL 0.5897 mL 1.4742 mL
25 mM 0.0472 mL 0.2359 mL 0.4717 mL 1.1793 mL
30 mM 0.0393 mL 0.1966 mL 0.3931 mL 0.9828 mL
40 mM 0.0295 mL 0.1474 mL 0.2948 mL 0.7371 mL
50 mM 0.0236 mL 0.1179 mL 0.2359 mL 0.5897 mL
60 mM 0.0197 mL 0.0983 mL 0.1966 mL 0.4914 mL
80 mM 0.0147 mL 0.0737 mL 0.1474 mL 0.3685 mL
100 mM 0.0118 mL 0.0590 mL 0.1179 mL 0.2948 mL
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DMT-5Me-dC(Bz)-CE Phosphoramidite Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMT-5Me-dC(Bz)-CE Phosphoramidite105931-57-5DNA/RNA Synthesislocked nucleic acids (LNAs)probespectralInhibitorinhibitorinhibit

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