136834-22-5

DMT-2'fluoro-da(bz) amidite Chemical Structure
136834-22-5

Chemical Structure

DMT-2'fluoro-da(bz) amidite

  • CAS No.: 136834-22-5
  • Formula:C47H51FN7O7P
  • Molecular Weight:875.92

IUPAC Name: (2R,3R,4R,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-fluorotetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

InChIKey: VCCMVPDSLHFCBB-MSIRFHFKSA-N

SMILES: COC(C=C1)=CC=C1C(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)OC[C@@H]4[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)[C@@H](F)[C@H](N5C6=NC=NC(NC(C7=CC=CC=C7)=O)=C6N=C5)O4

Biological Activity: DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity[1].

Cat. No. Product Name Purity Description Pricing
HY-21997
DMT-2'fluoro-da(bz) amidite 99.6% DMT-2'fluoro-da(bz) amidite is a key intermediate for synthesizing antisense oligonucleotides with high nuclease resistance, high RNA binding affinity, and maintained base-pair specificity.
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This product is a controlled substance and not for sale in your territory.

This product is not for sale in your territory.

This compound is listed in the SVHC (Substances of Very High Concern) candidate list of ECHA (European Chemicals Agency).

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References