325683-97-4
Chemical Structure
DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite
- CAS No.: 325683-97-4
- Formula:C54H57N8O9P
- Molecular Weight:993.05
IUPAC Name: 2-acetamido-9-((2R,3R,4S)-4-(bis(4-methoxyphenyl)(phenyl)methoxy)-3-(((2-cyanoethoxy)(diisopropylamino)phosphanyl)oxy)tetrahydrofuran-2-yl)-9H-purin-6-yl diphenylcarbamate
InChIKey: QGLNDUMJEPXLMP-DMYMLFOFSA-N
SMILES: CC(C)N(C(C)C)P(O[C@@H]1[C@@H](OC(C2=CC=CC=C2)(C3=CC=C(OC)C=C3)C4=CC=C(OC)C=C4)CO[C@H]1N(C=N5)C6=C5C(OC(N(C7=CC=CC=C7)C8=CC=CC=C8)=O)=NC(NC(C)=O)=N6)OCCC#N
Biological Activity: DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite | 98.38% | DMTr-TNA-G(O6-CONPh2)(N2Ac)-amidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | ||||||||||||||||||||
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Keywords
