LNA-A(Bz) amidite
Based on 1 Customer Validation
LNA-A (Bz) amidite is a phosphoramidite monomer applicable for oligonucleotide synthesis, such as the synthesis of miniature LNA anti-miRNA-122 antisense oligonucleotides.
For research use only. We do not sell to patients.
- Purity: 95.0%
- CAS No.: 206055-79-0
- Formula: C48H52N7O8P
- Molecular Weight:885.94
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All DNA/RNA Synthesis Isoforms
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Biological Activity
LNA-A(Bz) amidite serves as a viable monomer, alongside other phosphoramidite monomers, for the solid-phase synthesis of the scrambled control tiny LNA oligonucleotide tinyCtr-5G3, enabling production of a purified, sequence-specific construct[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 206055-79-0
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Appearance Solid
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Molecular Weight 885.94
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Formula C48H52N7O8P
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Color White to off-white
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SMILES
COC1=CC=C(C(OC[C@@]2([C@H]3OP(OCCC#N)N(C(C)C)C(C)C)CO[C@@]3([H])[C@H](N4C=NC5=C(NC(C6=CC=CC=C6)=O)N=CN=C54)O2)(C7=CC=C(OC)C=C7)C8=CC=CC=C8)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 100 mg/mL (112.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1287 mL | 5.6437 mL | 11.2874 mL | 28.2186 mL |
| 5 mM | 0.2257 mL | 1.1287 mL | 2.2575 mL | 5.6437 mL | |
| 10 mM | 0.1129 mL | 0.5644 mL | 1.1287 mL | 2.8219 mL | |
| 15 mM | 0.0752 mL | 0.3762 mL | 0.7525 mL | 1.8812 mL | |
| 20 mM | 0.0564 mL | 0.2822 mL | 0.5644 mL | 1.4109 mL | |
| 25 mM | 0.0451 mL | 0.2257 mL | 0.4515 mL | 1.1287 mL | |
| 30 mM | 0.0376 mL | 0.1881 mL | 0.3762 mL | 0.9406 mL | |
| 40 mM | 0.0282 mL | 0.1411 mL | 0.2822 mL | 0.7055 mL | |
| 50 mM | 0.0226 mL | 0.1129 mL | 0.2257 mL | 0.5644 mL | |
| 60 mM | 0.0188 mL | 0.0941 mL | 0.1881 mL | 0.4703 mL | |
| 80 mM | 0.0141 mL | 0.0705 mL | 0.1411 mL | 0.3527 mL | |
| 100 mM | 0.0113 mL | 0.0564 mL | 0.1129 mL | 0.2822 mL |
LNA-A(Bz) amidite Related Classifications
Cat. No.: HY-W570887
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- LNA-A(Bz) amidite
- 206055-79-0
- Phosphoramidites
- DNA/RNA Synthesis
- Drug Intermediate
- phosphoramidite monomers
- LNA anti-miRNA-122 antisense oligonucleotides
- lipid metabolism disorder
- solid-phase synthesis
- scrambled control tiny LNA oligonucleotide tinyCtr-5G3
- 2',4'-BNA/LNA phosphoramidite monomer
- cholesterol
- Inhibitor
- inhibitor
- inhibit