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Adenine hydrochloride

(Synonyms: 6-Aminopurine hydrochloride; Vitamin B4 hydrochloride)
24 Cited Publications
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Based on 24 publication(s) in Google Scholar

Adenine hydrochloride (6-Aminopurine hydrochloride), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine hydrochloride acts as a chemical component of DNA and RNA. Adenine hydrochloride also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

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  • Purity: 99.89%
  • CAS No.: 2922-28-3
  • Formula: C5H6ClN5
  • Molecular Weight:171.59
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Adenine hydrochloride Chemical Structure
    Adenine hydrochloride Chemical Structure
  • Experimental Validation Results for Adenine hydrochloride
  • Experimental Validation Results for Adenine hydrochloride
  • Experimental Validation Results for Adenine hydrochloride
  • Experimental Validation Results for Adenine hydrochloride
  • Experimental Validation Results for Adenine hydrochloride
CAS No.: 2922-28-3
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  • Adenine hydrochloride Chemical Structure
    Adenine hydrochloride Chemical Structure
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    Adenine hydrochloride purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]

    Customer Validation
     Capsaicin (10 and 15mg/kg, i.p.,once per week for 8 weeks) treatment lessened the deposition of ECM proteins in the kidneys from Adenine (0.25% w/w)-fed mice. Representative images of MTS (blue color), Picrosirius Red staining (red color), and IF staining of fibronectin (red color) and COL1A1 (green color) for kidney sections from adenine-fed (Adenine) or normal-fed (Ctrl) mice. Scale bars are 50 μm.

  • 1/16

    Adenine hydrochloride purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]

    Customer Validation
     Capsaicin (10 and 15 mg/kg, i.p., once per week for 8 weeks) treatment lessened the deposition of ECM proteins in the kidneys from Adenine (0.25% w/w)-fed mice. WB images of fibronectin and COL1A1 expressions in kidney lysates from mice.

  • 1/16

    Adenine hydrochloride purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]

    Customer Validation
     Capsaicin(10 or 15 mg/kg, i.p., once per week for 8 weeks) improved survival rate of Adenine (0.25% w/w)-fed mice. (A) Relative weight curves of indicated mice as described in A (n = 6). Mouse weight is measured once per 3 days, the initial weight is set to 1, and day 0 means the time point starting Adenine-rich diet. (B) Kaplan-Meier survival analysis of indicated mice as described in A (n = 12). Data are means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001.

  • 1/16

    Adenine hydrochloride purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]

    Customer Validation
     Capsaicin(10 or 15 mg/kg, i.p., once per week for 8 weeks) improved kidney function of Adenine (0.25% w/w)-fed mice. Concentrations of serum creatinine, urea, and albumin from mice (n = 8). Data are means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001.

  • 1/16

    Adenine hydrochloride purchased from MedChemExpress. Usage Cited in: Phytomedicine. 2022 Mar 21;100:154067. [Abstract]

    Customer Validation
     Capsaicin(10 or 15 mg/kg, i.p., once per week for 8 weeks) treatment prevented phenotypic alteration of tubular epithelial cells in the kidneys from Adenine (ADE) (0.25% w/w)-fed mice. Representative IHC staining images of E-cadherin and vimentin kidney sections from mice. Scale bars are 25 μm.

  • Adenine hydrochloride