1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Endogenous Metabolite Chemical

Endogenous Metabolite Chemical

Endogenous Metabolite Chemicals (14):

Cat. No. Product Name Effect Purity
  • HY-113491
    3-Phosphoglyceric acid
    Chemical 99.88%
    3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. 3-Phosphoglyceric acid is involved in alveolar macrophage epigenetic regulation.
  • HY-141452
    Propanedial (13.88 mM in water)
    Chemical
    Propanedial (Malondialdehyde) (13.88 mM in water) is one of the final products of lipid peroxidation. Propanedial causes protein inactivation, DNA damage and cross-linking by forming stable covalent adducts with biological macromolecules, which is the main mechanism for its cytotoxicity and genotoxicity. Propanedial production increases with the elevation of free radicals. Propanedial is a key biomarker for evaluating the level of cellular oxidative stress[1][2][3].
  • HY-164238
    LysoPC(18:3)
    Chemical
    LysoPC(18:3) is a lysophospholipid (LyP). LysoPC(18:3) can be used as a lipid biomarker in the diagnosis of breast cancer.
  • HY-28247
    N-Formylkynurenine
    Chemical 98.88%
    N-Formylkynurenine is an intermediate in the catabolism of tryptophan. It is a formylated derivative of kynurenine. The formation of N-formylkynurenine is catalyzed by heme dioxygenases.
  • HY-137499
    NT1-O12B
    Chemical
    NT1-O12B, an endogenous chemical and a neurotransmitter-derived lipidoid (NT-lipidoid), is an effective carrier for enhanced brain delivery of several blood-brain barrier (BBB)-impermeable cargos. Doping NT1-O12B into BBB-impermeable lipid nanoparticles (LNPs) gives the LNPs the ability to cross the BBB. NT-lipidoids formulation not only facilitate cargo crossing of the BBB, but also delivery of the cargo into neuronal cells for functional gene silencing or gene recombination.
  • HY-B0152S
    Adenine-d
    Chemical 99.91%
    Adenine-d is the deuterium labeled Adenine. Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.
  • HY-158801
    Arachidonoyl-L-carnitine chloride
    Chemical 99.64%
    Arachidonoyl-L-carnitine (C20:4 Carnitine) chloride is an arachidonic acid-L-carnitine complex.
  • HY-139312
    L-Mannitol
    Chemical 99.80%
    L-mannitol is a compound can be used for  the compound sweetener synthesis.
  • HY-135015
    Tetradecanenitrile
    Chemical
    Tetradecanenitrile is a nitrogen-containing saturated long-chain aliphatic nitrile that can be found in Pseudomonas veronii R02. Tetradecanenitrile can be used for the research of multiresistant Staphylococcus aureus infection.
  • HY-N11189
    α-D-Ribose-5-phosphate
    Chemical
    α-D-Ribose-5-phosphate is an important intermediate metabolite in the pentose phosphate pathway and in the purine metabolism pathway.
  • HY-148596
    UDP-GlcNAc
    Chemical
    UDP-GlcNAc (UDP-N-Acetyl-D-glucosamine) is an important component and precursor of bacterial peptidoglycan. UDP-GlcNAc also acts as a full agonist of the P2Y14 receptor and inhibits the formation of cAMP. UDP-GlcNAc can be used in studies related to bacterial infections.
  • HY-134349A
    8-PIP-NAD+ sodium
    Chemical
    8-PIP-NAD+ (sodium) (8-Piperidino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-PIP-NAD+ (sodium) can be used in the determination of poly(ADP-ribose) polymerase (PARP) target proteins. 8-PIP-NAD+ (sodium) is a synthetic intermediate in the synthesis of cyclic ADP-ribose (cADPR) derivatives.
  • HY-134300A
    8-DMA-NAD+ sodium
    Chemical
    8-DMA-NAD+ (sodium) (8-Dimethylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-DMA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations.
  • HY-134305A
    8-MA-NAD+ sodium
    Chemical
    8-MA-NAD+ (sodium) (8-Methylamino-NAD+ (sodium)) is a derivative of the signaling molecule and enzyme cofactor NAD+ (HY-B0445). 8-MA-NAD+ (sodium) can be used in the screening of analog-sensitive poly (ADP-ribose) polymerase 1 (PARP1) gatekeeper mutations. 8-MA-NAD+ (sodium) can be used in the synthesis of cyclic ADP-ribose (cADPR) derivatives.