56-65-5
56-65-5
Chemical Structure
ATP
Synonym(s): Adenosine 5'-triphosphate
- CAS No.: 56-65-5
- Formula:C10H16N5O13P3
- Molecular Weight:507.18
IUPAC Name: ((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
InChIKey: ZKHQWZAMYRWXGA-KQYNXXCUSA-N
SMILES: O=P(O)(O)OP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1O)(O)=O)(O)=O
Biological Activity: ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ATP | 99.88% | ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP (Standard) | 95.70% | ATP (Adenosine 5'-triphosphate) (Standard) is the analytical standard of ATP (HY-B2176). This product is intended for research and analytical applications. ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP-13C10,15N5 ammonium solution (100mM) | 98.13% | ATP-13C10,15N5 (Adenosine 5'-triphosphate-ATP-13C10,15N5) ammonium solution (100 mM) is the 13C10,15N5-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP-13C2 dilithium | 96.0% | ATP-13C2 (Adenosine 5'-triphosphate-ATP-13C2) dilithium is the 13C2-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP-13C10,15N5,d14 (dilithium) | ATP-13C10,15N5,d14 (Adenosine 5'-triphosphate-13C10,15N5,d14) dilithium is the 13C-, 15N- and deuterium labeled ATP dilithium. ATP (Adenosine 5'-triphosphate) is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | |||||||||||||||||||||
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ATP-13C10 dilithium | 99.97% | ATP-13C10 (Adenosine 5'-triphosphate-ATP-13C10) dilithium is the 13C10-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP-d14 dilithium | 99.98% | ATP-d14 (Adenosine 5'-triphosphate-ATP-d14) dilithium is the d14-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP-13C10,15N5 dilithium | 99.82% | ATP-13C10,15N5 (Adenosine 5'-triphosphate-ATP-13C10,15N5) dilithium is the 13C10,15N5-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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Adenosine 5'-triphosphate(ATP)-d4 ammonium solution (100mM) | 98.46% | Adenosine 5'-triphosphate(ATP)-d4 ammonium solution (100 mM) is the deuterium labeled Adenosine 5'-triphosphate(ATP) ammonium. | ||||||||||||||||||||
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ATP-15N5,d14 dilithium | 98% | ATP-15N5,d14 (Adenosine 5'-triphosphate-ATP-15N5,d14) dilithium is the 15N5,d14-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP-15N5 dilithium | 99.99% | ATP-15N5 (Adenosine 5'-triphosphate-ATP-15N5) dilithium is the 15N5-labeled ATP (HY-B2176). ATP is a central component of energy storage and metabolism in vivo. ATP provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP is an important endogenous signaling molecule in immunity and inflammation. ATP can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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2'-NH2-ATP | 2'-NH2-ATP (2'-Amino-2'-deoxyadenosine-5'-triphosphate), an adenosine derivative, is a weak competitive inhibitor of ATP, with a Ki of 2.3 mM. 2'-NH2-ATP can be used in nucleic acid labeling. | |||||||||||||||||||||
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Ara-ATP | Ara-ATP is an ATP-competitive poly (A) polymerase (poly (A) polymerase) inhibitor with a Ki value of 4 μM for the chromatin-bound form and a Ki value of 60 μM for the nucleoplasmic (free) form. Ara-ATP blocks pre-mRNA 3' end processing by inhibiting endonucleolytic cleavage, poly (A) addition, and the formation of cleavage and polyadenylation-specific RNA-protein complexes. Ara-ATP selectively inhibits initial polyadenylation rather than poly (A) elongation. Ara-ATP is used in the study of viral infections. | |||||||||||||||||||||
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2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate | 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate (2'-Fluoro dATP) is a monomeric raw material that can be used for nucleic acid synthesis. | |||||||||||||||||||||
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6-Me-ATP | 6-Me-ATP (N6-Methyl-ATP) is an N6-modified ATP derivative. 6-Me-ATP exhibits excellent binding affinity for GSK3 and acts as a phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptides. 6-Me-ATP is applicable to research related to Alzheimer's disease. | |||||||||||||||||||||
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Sp-ATPαS | Sp-ATPαS is a competitive P2Y1 purinergic receptor antagonist and an ATP (HY-B2176) analog. Sp-ATPαS antagonizes ADP-induced calcium mobilization. | |||||||||||||||||||||
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Rp-ATPαS | Rp-ATPαS is a monomeric raw material that can be used for nucleic acid synthesis. | |||||||||||||||||||||
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Guanosine 5'-triphosphate(GTP)-d4 ammonium salt | Guanosine 5'-triphosphate(GTP)-d4 (ammonium salt) is the deuterium labeled Guanosine 5'-triphosphate(GTP) ammonium salt. | |||||||||||||||||||||
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3′-Deoxyadenosine 5′-triphosphate | 3′-Deoxyadenosine 5′-triphosphateCan be used for nucleic acid synthesis. | |||||||||||||||||||||
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LNA-ATP | LNA-ATP is a nucleotide analog that can be used in the synthesis of oligonucleotides. | |||||||||||||||||||||
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Adenosine tetraphosphate | Adenosine tetraphosphate is a natural nucleotide present in many biological systems. Adenosine tetraphosphate produces a reduction in the intraocular pressure in normotensive rabbit eyes. | |||||||||||||||||||||
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ATP dipotassium | 98.69% | ATP (Adenosine 5'-triphosphate) dipotassium is a central component of energy storage and metabolism in vivo. ATP dipotassium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP dipotassium is an important endogenous signaling molecule in immunity and inflammation. ATP dipotassium can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP dipotassium has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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ATP magnesium | 98.0% | ATP (Adenosine 5'-triphosphate) magnesium is a central component of energy storage and metabolism in vivo. ATP magnesium provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP magnesium is an important endogenous signaling molecule in immunity and inflammation. ATP magnesium can activate the NLRP3 inflammasome and induce IL-1β and chemokines secretion. ATP magnesium has anti-bacterial infection effects and can protect mice against bacterial infection in mice. | ||||||||||||||||||||
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Adenosine 5'-diphosphate (Standard) | 98.39% | Adenosine 5'-diphosphate (Standard) is the analytical standard of Adenosine 5'-diphosphate. This product is intended for research and analytical applications. Adenosine 5'-diphosphate (Adenosine diphosphate) is a nucleoside diphosphate. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors. In Vitro: Adenosine 5'-diphosphate consists of the pyrophosphate group, the pentose sugar ribose, and the nucleobase adenine. Adenosine 5'-diphosphate is the product of ATP dephosphorylation by ATPases. ADP is converted back to ATP by ATP synthases. ATP is an important energy transfer molecule in cells. Adenosine 5'-diphosphate is utilized in a wide number of cellular processes, including respiration, biosynthetic reactions, motility, and cell division. | ||||||||||||||||||||
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Adenosine 5′-O-1-thiotriphosphate | Adenosine 5′-O-(1-thiotriphosphate) is an α-Phosphate modified adenosine nucleotide. | |||||||||||||||||||||
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References
- [1]. Swennen EL, et al. Immunoregulatory effects of adenosine 5'-triphosphate on cytokine release from stimulated whole blood. Eur J Immunol. 2005 Mar;35(3):852-8. [Content Brief]
- [2]. M J L Bours, et al. Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther. 2006 Nov;112(2):358-404. [Content Brief]
- [3]. Shuo Xu, et al. Doxycycline inhibits NAcht Leucine-rich repeat Protein 3 inflammasome activation and interleukin-1β production induced by Porphyromonas gingivalis-lipopolysaccharide and adenosine triphosphate in human gingival fibroblasts. Arch Oral Biol. 2019 Nov;107:104514. [Content Brief]
- [4]. Yang Xiang, et al. Adenosine-5'-Triphosphate (ATP) Protects Mice against Bacterial Infection by Activation of the NLRP3 Inflammasome. PLoS One. 2013; 8(5): e63759. [Content Brief]
