6-Me-ATP
6-Me-ATP (N6-Methyl-ATP) is an N6-modified ATP derivative. 6-Me-ATP exhibits excellent binding affinity for GSK3 and acts as a phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptides. 6-Me-ATP is applicable to research related to Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 3130-39-0
- Formula: C11H18N5O13P3
- Molecular Weight:521.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
6-Me-ATP (10-200 μM; 20 min-2 h) binds 18 distinct human kinases (including GSK3α and GSK3β) from HEK293T cell lysate, with GSK3α exhibiting similar binding affinity to 6-Me-ATP as to native ATP[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3130-39-0
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Molecular Weight 521.21
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Formula C11H18N5O13P3
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SMILES
CNC1=C2N=CN([C@@H]3O[C@H](COP(O)(OP(OP(O)(O)=O)(O)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
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Synonyms
N6-Methyl-ATP
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-Me-ATP Related Classifications
HY-134393 Related Classifications
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