Ara-ATP

Ara-ATP (0.25-2 mM; 60 min) inhibits the polyadenylation of SV40L pre-mRNA in HeLa nuclear extracts in a dose-dependent manner, with an inhibition rate of 85% at 0.5 mM and complete inhibition at 2 mM^[1].
Ara-ATP (1.0-2.0 mM; 1 h) completely impairs 3' end processing of adenovirus L3 pre-mRNA in HeLa nuclear extracts at 1 mM^[1].
Ara-ATP (0.5-2.0 mM; 30 min) inhibits endonucleolytic cleavage of SV40L pre-mRNA in HeLa nuclear extracts, with complete inhibition at 2 mM^[1].
Ara-ATP (0.5-2.0 mM; 1 h) inhibits the polyadenylation of "pre-cleaved" SV40L pre-mRNA in HeLa nuclear extract in a dose-dependent manner, with complete inhibition at 2 mM^[1].
Ara-ATP (2 mM; 30-90 min) inhibits the formation of post-cleavage and polyadenylation-specific RNA-protein complexes during SV40L pre-mRNA 3'-end processing in HeLa nuclear extracts^[1].
Ara-ATP (1-200 μM) competitively inhibits rat liver chromatin-associated poly (A) polymerase with a K_i of 4 μM, and inhibits nucleoplasmic poly (A) polymerase with a K_i of 60 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.