5-Fluorouracil (Synonyms: 5-FU)

Name: 5-Fluorouracil
Brand: MedChemExpress
SKU: HY-90006
Rating: 5.0 (313 reviews)

Cat. No.: HY-90006 Purity: 99.99%: Data Sheet
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5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV.

For research use only. We do not sell to patients.

CAS No. : 51-21-8

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10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
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10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
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50 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	In-stock	Estimated Time of Arrival: December 31
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Customer Review

Based on 313 publication(s) in Google Scholar

Other Forms of 5-Fluorouracil:

313 Publications Citing Use of MCE 5-Fluorouracil

IHC

RT-PCR

Cell Proliferation/Viability Assay

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Nat Med. 2024 Mar;30(3):749-761. [Abstract]; The relative cell viability of shCtl-, shNDUFB8-, and shCEMIP2-transfected cells was detected by XTT assay after paclitaxel plus gemcitabine treatment (A+G), single-agent 5-Fu (5-FU), and the FOLFIRINOX chemotherapy cocktail [FU+IRI+OXA: 5-FU (5 μM)+Irinotecan (SN-38) +Oxaliplatin] for 48h.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Cell. 2024 Apr 25;187(9):2288-2304.e27. [Abstract]; SP1 and SLC6A6 levels in SGC7901 cells treated with fluorouracil (0.5 μg/mL) for the indicated times.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Mol Cancer. 2024 Jan 24;23(1):23. [Abstract]; A CCK-8 assay was used to investigate the effects of LINC01852 overexpression and knockdown on the sensitivity of CRC cells to 5-FU and L-OHP. CRC cells were exposed to gradually increasing concentrations of 5-FU (1-3 μM) and L-OHP for 48 h

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Clin Invest. 2024 Mar 7;134(10):e172716. [Abstract]; The given cell lines were treated with 250 nM osimertinib (Osim), 1.25 μM Etoposide (VP-16), 125 nM Doxorubicin (DXR), 5 nM Paclitaxel, 10 μM Cisplatin, 25 μM Carboplatin, 25 nM Gemcitabine, 20 nM 5-Fluorouracil (5-FU), 25 μM Cyclophosphamide, 25 μM Capecitabine, or 10 nM Vincristine alone or in combination for 3 days. Cell numbers were then measured using the SRB assay.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: ACS Nano. 2023 Nov 28;17(22):22901-22915. [Abstract]; 5-FU (120 mg/kg; i.p.; once daily for 2 consecutive days) induces increased infiltration of CD45+ immune cells into the intestinal lumen of Dgcr8-deficient mice, accompanied by elevated levels of the pro-inflammatory cytokines IFNγ and pNF-κB.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2022 Oct;9(30):e2200717. [Abstract]; A transient upregulation and subsequent downregulation of RSK2 phosphorylation at Thr577 by 5-Fluorouracil (5-FU), which is accompanied by the accumulation of γ‐H2AX phosphorylation in a time‐dependent manner.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2022 Oct;9(30):e2200717. [Abstract]; In Hct116 cells, the inhibitory effects of 5-Fluorouracil (5-FU on cell growth at 2-10 μM are significantly enhanced by RSK2 or PAK4 inhibitors in short‐term and long‐term assays.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Immunother Cancer. 2022 Aug;10(8):e004006. [Abstract]; Hep3B and Huh7 cells are treated with 5-Fluorouracil for 24 h, then the cellular protein expression of p-IRF3 and pP65 is detected by immunoblotting.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Int J Biol Sci. 2022 Apr 11;18(7):2882-2897. [Abstract]; Representative immunoblots assessing apoptosis induced by 5-Fluorouracil (5-FU) in immortalized human ventricular myocytes (AC16).

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Gastroenterology. 2021 Nov;161(5):1601-1614.e23. [Abstract]; Bar graphs show the GI50 of 5-fluoruracil (48 h), irinotecan (48 h), gemcitabine (48 h), paclitaxel (48 h), and oxaliplatin (48 h) in PDAC cells in combination with bioactive hexapeptides (NTAIYY and PTTIYY) or controls (saline and NTAIYA).

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; Cell viability upon treatment with 5-Fluorouracil (5-FU; 60 μM), SR140333, or Aprepitant either as single agents or in combination at 24 h in HCT116 cells.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; Western blotting of drug-resistant proteins in HCT116/5-FU cells treated with 5-Fluorouracil (5-FU; 80 μM) at 48 h.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; ER stress pathways in HCT116/5-FU cells treated with 5-Fluorouracil (5-FU; 60 μM) with SR140333 or Aprepitant either as single agents or in combination at 24 h.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2021 Nov;8(21):e2101936. [Abstract]; The combination of SR140333 or aprepitant and 5-Fluorouracil (5-FU; mg/kg) decreases the expression levels of ABCC1, ABCG2, p-ERK1/2, and c-Myc and increased those of p-PERK, ATF4, and CHOP compared with 5-FU treatment alone.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Exp Clin Cancer Res. 2021 Apr 30;40(1):150. [Abstract]; Inhibition rate of proliferation in pcDNA3.1 or ZBTB28 transfected cells treated with gradient concentration of 5-FU for 72 hours.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Cell Death Dis. 2021 Apr 1;12(4):338. [Abstract]; SW620, CACO2, and HCT15 cells are treated with different concentrations of UTD1 and 5-Fluorouracil (5-FU), and cell viability is measured by CCK-8.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2026813118. [Abstract]; Overexpression of RMRP impairs 5-FU-induced p53 activation determined by IB.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Proc Natl Acad Sci U S A. 2021 Jul 20;118(29):e2026813118. [Abstract]; Overexpression of RMRP impairs 5-FU–induced p53 activation determined by RT-qPCR.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Int J Biochem Cell Biol. 2018 Mar:96:9-19. [Abstract]; Hep3B cells are treated with 2 μmol Shikonin, 5-FU, BSNQ or OSNQ for different times (3, 6, 12 and 24 h), and stained with Annexin V and PI. The apoptotic cells are detected by fluorescence microscopy and quantified as percentages.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Cell Biochem. 2019 May;120(5):8447-8456. [Abstract]; MKN45 and MKN28 cells transfected with empty and DEC2 vectors are incubated in control medium or 5-Fu of 10 μM for 48 hours, then proliferation ratio of these cells is figured by EdU incorporation assay.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Cell Biochem. 2019 May;120(5):8447-8456. [Abstract]; The expressions of apoptotic-related proteins, cleaved-PARP, caspase-3-active and survivin are detected in MKN45, MKN45+5-Fu, MKN45-EV, MKN45-DEC2, MKN45-DEC2+5-Fu, MKN28, MKN28+5-Fu, MKN28-EV, MKN28-DEC2, MKN28-DEC2+5-Fu cells using Western blot analysis.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: J Cell Biochem. 2019 May;120(5):8447-8456. [Abstract]; The expressions of apoptotic-related proteins, cleaved-PARP, caspase-3-active are detected in control, STAT5A, STAT5A+5-Fu, DEC2+5-Fu, DEC2/STAT5A+5-Fu of MKN45 and MKN28 cell lines using Western blot analysis.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Biochem Biophys Res Commun. 2018 Jun 27;501(3):636-642. [Abstract]; Immunoblot analysis of the expression levels of BCL-2 and BAX after treatment of HCT116 TP53^-/- cells with 20 μM 5-FU and 1.25 μM DHA alone or in combination for 48 h. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) served as a loading control.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Med Sci Monit. 2018 Sep 21:24:6666-6672. [Abstract]; Expression of protein of OPA1, Mfn1, Mfn2, Drp1 and Fis1 in heart mitochondria of rats treated with different 5-FU concentrations. The control group is intraperitonealled injection with same amount of physiological saline.

: 5-Fluorouracil purchased from MedChemExpress. Usage Cited in: Tumour Biol. 2016 Jul;37(7):8811-24. [Abstract]; Assays for autophagy activity. Immunoblot analysis for LC3B. Compared with the Lenti-NC cells, the Lenti-CD44v6 cells display a higher intensity of autophagy flux but not steady-state levels when treated with 5-FU (*P<0.001).

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Biological Activity
Protocol
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target^[1]^[6]

HIV

Cellular Effect

Cell Line	Type	Value	Description	References
143B	IC₅₀	13.01 μM Compound: FUra	Cytotoxicity against human 143B cells after 72 hrs by SRB assay Cytotoxicity against human 143B cells after 72 hrs by SRB assay	[PMID: 27073055]
143B	IC₅₀	16.31 μM Compound: FUra	Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay Cytotoxicity against human thymidine kinase deficient 143B cells after 72 hrs by SRB assay	[PMID: 27073055]
143B	IC₅₀	25.216 μM Compound: 5-FU	Antiproliferative activity against human 143B cells after 48 hrs by MTT assay Antiproliferative activity against human 143B cells after 48 hrs by MTT assay	[PMID: 29223717]
2008	IC₅₀	4.2 μM Compound: 1, 5-FU	Growth inhibition of human 2008 cells by crystal violet assay Growth inhibition of human 2008 cells by crystal violet assay	[PMID: 23075414]
2008	IC₅₀	6 μM Compound: 5FU	Cytotoxicity against human 2008 cells Cytotoxicity against human 2008 cells	[PMID: 30035541]
4T1	IC₅₀	23 μM Compound: 5 Fluorouracil	Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against mouse 4T1 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
4T1	IC₅₀	28.12 μM Compound: 5-Fu	Anticancer activity against mouse 4T1 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against mouse 4T1 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
786-0	GI₅₀	0.72 μM Compound: 5-FU	Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human 786-0 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
786-0	GI₅₀	0.72 μM Compound: 5-FU	Anticancer activity against human 786-0 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human 786-0 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
786-0	IC₅₀	0.72 μM Compound: 5-Fluorouracil	Cytotoxicity against human 786-0 cells assessed as cell growth inhibition Cytotoxicity against human 786-0 cells assessed as cell growth inhibition	[PMID: 36470105]
786-0	IC₅₀	2.29 μM Compound: 5-Fu	Antiproliferative activity against human 786-0 cells incubated for 72 hrs by SRB method Antiproliferative activity against human 786-0 cells incubated for 72 hrs by SRB method	[PMID: 39054645]
786-0	IC₅₀	> 10 μM Compound: 5-fluorouracil	Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human 786-0 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
9L	IC₅₀	1 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against 9L cells Tested in vitro for anticancer activity against 9L cells	[PMID: 10072683]
A-375	IC₅₀	21.09 μM Compound: 5-Fu	Anticancer activity against human A375 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against human A375 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
A-375	IC₅₀	3.52 μM Compound: 5-FU	Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human A-375 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
A-375	IC₅₀	46.55 μM Compound: 5-FU	Cytotoxicity against human A375 cells after 48 hrs by MTT assay Cytotoxicity against human A375 cells after 48 hrs by MTT assay	[PMID: 22483608]
A-375	IC₅₀	5.98 μM Compound: 5-Fu	Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
A-375	IC₅₀	69.65 μM Compound: 5-Fu	Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human A-375 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 39163776]
A-431	ED₅₀	44 μM Compound: 5-fluorouracil	Cytotoxicity against human A431 cells by MTT assay Cytotoxicity against human A431 cells by MTT assay	[PMID: 12027771]
A-431	IC₅₀	0.018 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A431 cells after 48 hrs by MTT assay Antiproliferative activity against human A431 cells after 48 hrs by MTT assay	[PMID: 19423198]
A-431	IC₅₀	2.17 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human A431 cells after 48 hrs by MTT assay Cytotoxicity against human A431 cells after 48 hrs by MTT assay	[PMID: 20800480]
A2780	GI₅₀	3.5 μM Compound: 5FU	Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
A2780	GI₅₀	4.4 μM Compound: 5-FU	Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A2780 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
A2780	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human A2780 after 24 hrs by MTT assay Cytotoxicity against human A2780 after 24 hrs by MTT assay	[PMID: 19338315]
A2780	IC₅₀	0.65 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human A2780 cells by MTT assay Cytotoxicity against human A2780 cells by MTT assay	[PMID: 18205316]
A2780	IC₅₀	12.93 μM Compound: 5-Fu	Cytotoxicity against human A2780 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human A2780 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
A2780	IC₅₀	14 μM Compound: 5-FU	Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human A2780 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
A2780	IC₅₀	3.932 μM Compound: 5-Fu	Cytotoxicity against human A2780 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A2780 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 38964974]
A2780	IC₅₀	32.11 μM Compound: 1; 5-FU	Growth inhibition of human A2780 cells incubated for 1.5 hrs by MTT assay Growth inhibition of human A2780 cells incubated for 1.5 hrs by MTT assay	[PMID: 38107178]
A2780	IC₅₀	36.29 μM Compound: 1; 5-FU	Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 1.5 hrs by CCK-8 assay Antiproliferative activity against human A2780 cells assessed as inhibition of cell growth incubated for 1.5 hrs by CCK-8 assay	[PMID: 38107178]
A2780	IC₅₀	5 μM Compound: 5-Fu	Cytotoxicity against human A2780 cells after 96 hrs by MTT assay Cytotoxicity against human A2780 cells after 96 hrs by MTT assay	[PMID: 16499317]
A2780	IC₅₀	5.1 μM Compound: 1, 5-FU	Growth inhibition of human A2780 cells by crystal violet assay Growth inhibition of human A2780 cells by crystal violet assay	[PMID: 23075414]
A2780	IC₅₀	5.4 μM Compound: 5-Fu	Cytotoxicity against human A2780 cells by MTT method Cytotoxicity against human A2780 cells by MTT method	[PMID: 23164710]
A2780	IC₅₀	7.21 μM Compound: 5-FU	Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human A2780 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
A498	GI₅₀	0.35 μM Compound: 5-FU	Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A498 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
A498	GI₅₀	0.35 μM Compound: 5-FU	Anticancer activity against human A498 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human A498 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
A498	IC₅₀	0.35 μM Compound: 5-Fluorouracil	Cytotoxicity against human A498 cells assessed as cell growth inhibition Cytotoxicity against human A498 cells assessed as cell growth inhibition	[PMID: 36470105]
A498	IC₅₀	8.83 μM Compound: 5-fluorouracil	Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human A498 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
A549	EC₅₀	100 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 20409617]
A549	EC₅₀	3.61 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 12027739]
A549	ED₅₀	0.4 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 16309328]
A549	GI₅₀	0.18 μM Compound: 5-FU	Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A549/ATCC cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
A549	GI₅₀	0.18 μM Compound: 5-FU	Anticancer activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
A549	GI₅₀	10.7 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 48 hrs by MTT assay	[PMID: 32832031]
A549	GI₅₀	19.76 μM Compound: 4; 5-FU	Antiproliferative activity against human A549 cells measured after 48 hrs by SRB assay Antiproliferative activity against human A549 cells measured after 48 hrs by SRB assay	[PMID: 32683166]
A549	GI₅₀	2.09 μM Compound: 5-FU	Growth inhibition of human A549 cells after 48 hrs by SRB assay Growth inhibition of human A549 cells after 48 hrs by SRB assay	[PMID: 28400235]
A549	GI₅₀	2.2 μM Compound: 5-FU	Growth inhibition of human A549 cells measured after 48 hrs by SRB colorimetric assay Growth inhibition of human A549 cells measured after 48 hrs by SRB colorimetric assay	[PMID: 37137247]
A549	GI₅₀	2.2 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells assessed as reduction in cell growth Antiproliferative activity against human A549 cells assessed as reduction in cell growth	[PMID: 34847410]
A549	GI₅₀	2.4 μM Compound: 5FU	Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
A549	GI₅₀	3.6 μM Compound: fluorouracil	Cytotoxicity against human A549 cells after 72 hrs by SRB assay Cytotoxicity against human A549 cells after 72 hrs by SRB assay	[PMID: 23964677]
A549	GI₅₀	4.2 μM Compound: 5-Fluorouracil	Growth inhibition of human A549 cells after 48 hrs by SRB assay Growth inhibition of human A549 cells after 48 hrs by SRB assay	[PMID: 28898082]
A549	GI₅₀	4.55 μM Compound: 5-fluorouracil	Growth inhibition of human A549 cells after 48 hrs by SRB assay Growth inhibition of human A549 cells after 48 hrs by SRB assay	[PMID: 24797798]
A549	IC₅₀	0.01 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 48 hrs by SRB assay Cytotoxicity against human A549 cells after 48 hrs by SRB assay	[PMID: 25259515]
A549	IC₅₀	0.18 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as cell growth inhibition Cytotoxicity against human A549 cells assessed as cell growth inhibition	[PMID: 36470105]
A549	IC₅₀	0.18 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 18205316]
A549	IC₅₀	0.1 μg/mL Compound: 5-fluorouracil	Antitumor activity against human A549 cells Antitumor activity against human A549 cells	[PMID: 10579858]
A549	IC₅₀	0.26 μg/mL Compound: 5-FU	Inhibitory concentration of compound for cytotoxicity against A459 human lung cells was determined Inhibitory concentration of compound for cytotoxicity against A459 human lung cells was determined	[PMID: 11814824]
A549	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human A549 after 24 hrs by MTT assay Cytotoxicity against human A549 after 24 hrs by MTT assay	[PMID: 19338315]
A549	IC₅₀	0.42 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 3 days by MTT assay Cytotoxicity against human A549 cells after 3 days by MTT assay	[PMID: 22000925]
A549	IC₅₀	0.43 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 29254641]
A549	IC₅₀	0.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay	10.1039/C5MD00289C
A549	IC₅₀	0.69 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 32485532]
A549	IC₅₀	0.98 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed as growth inhibition measured at 48 hrs by SRB assay	[PMID: 24727462]
A549	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 24060486]
A549	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
A549	IC₅₀	1.16 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 27987485]
A549	IC₅₀	1.2 μM Compound: 5-F	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 28254697]
A549	IC₅₀	1.3 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 24835633]
A549	IC₅₀	1.3 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as cell inhibition measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell inhibition measured after 72 hrs by MTT assay	[PMID: 36774698]
A549	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26854375]
A549	IC₅₀	1.4 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 96 hrs by MTT assay Cytotoxicity against human A549 cells after 96 hrs by MTT assay	[PMID: 16499317]
A549	IC₅₀	1.54 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT method Cytotoxicity against human A549 cells by MTT method	[PMID: 23164710]
A549	IC₅₀	1.6 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 28431881]
A549	IC₅₀	1.65 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells assessed as growth inhibition after 24 to 48 hrs by sulforhodamine B assay	[PMID: 24996138]
A549	IC₅₀	1.65 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as reduction in cell growth by CCK8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell growth by CCK8 assay	[PMID: 33964443]
A549	IC₅₀	1.65 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells Antiproliferative activity against human A549 cells	[PMID: 35944853]
A549	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
A549	IC₅₀	1.7 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of A-549 tumor cell line from lung. Compound was tested for its inhibitory effect on the growth of A-549 tumor cell line from lung.	10.1016/0960-894X(96)00339-3
A549	IC₅₀	1.9 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
A549	IC₅₀	10.32 μM Compound: 5-FU	Antiproliferative activity in human A549 cells after 72 hrs by MTT assay Antiproliferative activity in human A549 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
A549	IC₅₀	10.5 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28073676]
A549	IC₅₀	10.55 μM Compound: 5-FU	Cytotoxicity against human A549 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
A549	IC₅₀	10.5 μg/mL Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
A549	IC₅₀	10.65 μM Compound: 5-FU	Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
A549	IC₅₀	10.85 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 18644718]
A549	IC₅₀	100.02 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
A549	IC₅₀	104.5 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human A549 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
A549	IC₅₀	108.7 μM Compound: 5-FU	Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
A549	IC₅₀	11.13 μM Compound: 5-FU	Anticancer activity against human A549 cells assessed as cell growth inhibition by MTT assay Anticancer activity against human A549 cells assessed as cell growth inhibition by MTT assay	[PMID: 36481599]
A549	IC₅₀	11.2 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
A549	IC₅₀	11.3 μM Compound: 5-FU	Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Anticancer activity against human A549 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 36481599]
A549	IC₅₀	11.3 μM Compound: 5-fluorouracil	Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
A549	IC₅₀	11.4 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
A549	IC₅₀	11.42 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
A549	IC₅₀	11.5 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells incubated for 72 hrs by SRB method Antiproliferative activity against human A549 cells incubated for 72 hrs by SRB method	[PMID: 39054645]
A549	IC₅₀	12.8 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 22840493]
A549	IC₅₀	12.92 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28863355]
A549	IC₅₀	13.18 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 29635165]
A549	IC₅₀	13.18 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
A549	IC₅₀	13.7 μM Compound: fluorouracil	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 21495659]
A549	IC₅₀	13.95 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition by MTT assay	[PMID: 27769034]
A549	IC₅₀	14.15 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 26227777]
A549	IC₅₀	14.53 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay	[PMID: 32992255]
A549	IC₅₀	14.96 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
A549	IC₅₀	15.1 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 28400238]
A549	IC₅₀	15.14 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
A549	IC₅₀	15.3 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
A549	IC₅₀	15.93 μM Compound: 2; 5-FU	Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human A549 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
A549	IC₅₀	16.1 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28117202]
A549	IC₅₀	16.63 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition by MTT assay	[PMID: 27913179]
A549	IC₅₀	16.96 μM Compound: 2; 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27322756]
A549	IC₅₀	17.02 μM Compound: 2; 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29202398]
A549	IC₅₀	17.3 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
A549	IC₅₀	18.55 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 38107169]
A549	IC₅₀	19.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29486954]
A549	IC₅₀	2.05 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 30243153]
A549	IC₅₀	2.05 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
A549	IC₅₀	2.13 μM Compound: 5-Fluorouracil	Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Anticancer activity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
A549	IC₅₀	2.33 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
A549	IC₅₀	2.36 μM Compound: 5-Fluorouracil	Cytotoxicity activity against human A549 cells incubated for 48 hrs by SRB assay Cytotoxicity activity against human A549 cells incubated for 48 hrs by SRB assay	[PMID: 34119830]
A549	IC₅₀	2.4 μM Compound: 5-fluorouracil	Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human A549 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
A549	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
A549	IC₅₀	2.53 μM Compound: 5-Fu	Antiproliferation activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human A549 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
A549	IC₅₀	2.65 μM Compound: 5-FU	Antitumor activity against human A549 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human A549 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
A549	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay	[PMID: 27311895]
A549	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 27875779]
A549	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 29133046]
A549	IC₅₀	2.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay Antiproliferative activity against human A549 cells after 72 hrs by WST8 assay	[PMID: 25919052]
A549	IC₅₀	2.9 mM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human A549 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27847140]
A549	IC₅₀	20.13 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 24211021]
A549	IC₅₀	20.8 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells by SRB method Cytotoxicity against human A549 cells by SRB method	[PMID: 19422203]
A549	IC₅₀	21.58 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 27133593]
A549	IC₅₀	22.28 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26363869]
A549	IC₅₀	22.5 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
A549	IC₅₀	22.62 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
A549	IC₅₀	22.8 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 39016216]
A549	IC₅₀	23.5 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 30108895]
A549	IC₅₀	23.57 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
A549	IC₅₀	24.2 μM Compound: 5-FU	Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay	[PMID: 39045852]
A549	IC₅₀	24.66 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
A549	IC₅₀	24.87 μg/mL Compound: 5-F	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 24342667]
A549	IC₅₀	25.3 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
A549	IC₅₀	25.36 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 37343499]
A549	IC₅₀	26 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by MTT assay	10.1039/C6MD00234J
A549	IC₅₀	27.08 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
A549	IC₅₀	28.64 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 30677614]
A549	IC₅₀	29.17 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
A549	IC₅₀	2 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells by SRB assay Cytotoxicity against human A549 cells by SRB assay	[PMID: 19700322]
A549	IC₅₀	3.08 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 36335743]
A549	IC₅₀	3.1 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT microassay Cytotoxicity against human A549 cells by MTT microassay	[PMID: 17320246]
A549	IC₅₀	3.1 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 18606546]
A549	IC₅₀	3.1 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells after 4 days by MTT assay Cytotoxicity against human A549 cells after 4 days by MTT assay	[PMID: 24359303]
A549	IC₅₀	3.2 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 22011319]
A549	IC₅₀	3.47 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26735909]
A549	IC₅₀	3.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 23665106]
A549	IC₅₀	3.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTS assay Antiproliferative activity against human A549 cells after 72 hrs by MTS assay	[PMID: 26703795]
A549	IC₅₀	3.52 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTS assay Antiproliferative activity against human A549 cells after 72 hrs by MTS assay	[PMID: 27575478]
A549	IC₅₀	3.52 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTS assay Cytotoxicity against human A549 cells by MTS assay	[PMID: 29843103]
A549	IC₅₀	3.85 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
A549	IC₅₀	3.9 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 39106494]
A549	IC₅₀	3.98 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27092413]
A549	IC₅₀	30.47 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
A549	IC₅₀	31.33 μM Compound: 5-FU	Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human A549 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
A549	IC₅₀	31.41 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition Cytotoxicity against human A549 cells assessed as cell growth inhibition	[PMID: 35809817]
A549	IC₅₀	31.52 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 22801644]
A549	IC₅₀	32.15 μM Compound: 5-Fu	Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxic activity against human A549 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 28011223]
A549	IC₅₀	32.4 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human A549 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
A549	IC₅₀	33.68 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition by MTT assay	[PMID: 31945642]
A549	IC₅₀	34.27 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 26883148]
A549	IC₅₀	34.27 μM Compound: 5FU	Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human A549 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
A549	IC₅₀	34.33 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23988357]
A549	IC₅₀	34.33 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 3 days by MTT assay Cytotoxicity against human A549 cells after 3 days by MTT assay	[PMID: 24095745]
A549	IC₅₀	34.34 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 24953029]
A549	IC₅₀	34.47 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 28754470]
A549	IC₅₀	34.47 μM Compound: 5-FU	Antiproliferative activity against human A549 cells by MTT assay Antiproliferative activity against human A549 cells by MTT assay	[PMID: 33109400]
A549	IC₅₀	34.86 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells by CCK8 assay Antiproliferative activity against human A549 cells by CCK8 assay	[PMID: 37939862]
A549	IC₅₀	34.89 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition Cytotoxicity against human A549 cells assessed as cell growth inhibition	[PMID: 35964428]
A549	IC₅₀	35.05 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 22483608]
A549	IC₅₀	35.41 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell growth Antiproliferative activity against human A549 cells assessed as inhibition of cell growth	[PMID: 36089111]
A549	IC₅₀	35.41 μM Compound: Fluorouracil	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 22809558]
A549	IC₅₀	35.41 μM Compound: Fluorouracil	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 25016234]
A549	IC₅₀	35.41 μM Compound: Fluorouracil	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 27128180]
A549	IC₅₀	36.3 μM Compound: 5-FU	Antiproliferative activity against human A549 cells incubated for 24 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 24 hrs by MTT assay	[PMID: 39045852]
A549	IC₅₀	36.34 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
A549	IC₅₀	36.8 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay Cytotoxicity against human A549 cells assessed as decrease in cell viability by MTT assay	[PMID: 29489361]
A549	IC₅₀	38.2 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 28371676]
A549	IC₅₀	38.23 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 2 days by MTT assay Cytotoxicity against human A549 cells after 2 days by MTT assay	[PMID: 25841196]
A549	IC₅₀	38.7 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 30737134]
A549	IC₅₀	39.86 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
A549	IC₅₀	39.86 μM Compound: 5-FU	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
A549	IC₅₀	4.1 μg/mL Compound: 5-Fu	Anticancer activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
A549	IC₅₀	4.21 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed cell viability after 48 hrs by SRB assay	[PMID: 23044370]
A549	IC₅₀	4.21 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 24956552]
A549	IC₅₀	4.3 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 30318440]
A549	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells by MTT assay Antiproliferative activity against human A549 cells by MTT assay	[PMID: 31546197]
A549	IC₅₀	4.52 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
A549	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human A549 cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
A549	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human A549 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
A549	IC₅₀	4.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 26222449]
A549	IC₅₀	40.38 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
A549	IC₅₀	44.05 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23558238]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Growth inhibition against human A549 cells after 48 hrs by MTT assay Growth inhibition against human A549 cells after 48 hrs by MTT assay	[PMID: 23999046]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 2 days by MTT assay Cytotoxicity against human A549 cells after 2 days by MTT assay	[PMID: 24767839]
A549	IC₅₀	44.05 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human A549 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
A549	IC₅₀	5.4 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human A549 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
A549	IC₅₀	5.6 μM Compound: 5-FU	Cytotoxicity against human A549 cells by MTT assay Cytotoxicity against human A549 cells by MTT assay	[PMID: 21515044]
A549	IC₅₀	5.62 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23920246]
A549	IC₅₀	5.64 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 24 hrs by MTT assay Cytotoxicity against human A549 cells after 24 hrs by MTT assay	[PMID: 22182926]
A549	IC₅₀	5.64 μM Compound: 5-Fu	Cytotoxicity against human A549 cells by after 48 hrs by MTT assay Cytotoxicity against human A549 cells by after 48 hrs by MTT assay	[PMID: 22579780]
A549	IC₅₀	5.64 μM Compound: 5-Fu	Growth inhibition of human A549 cells after 48 hrs by MTT assay Growth inhibition of human A549 cells after 48 hrs by MTT assay	[PMID: 23353737]
A549	IC₅₀	5.7 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 37859725]
A549	IC₅₀	5.91 μM Compound: 5-Fluoro uracil	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 19689125]
A549	IC₅₀	50.43 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
A549	IC₅₀	50.5 μM Compound: 5-FU	In vitro inhibitory concentration required against human lung carcinoma A-549 cell line was determined after 72 hrs of drug exposure using SRB method In vitro inhibitory concentration required against human lung carcinoma A-549 cell line was determined after 72 hrs of drug exposure using SRB method	[PMID: 15380199]
A549	IC₅₀	50.5 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 72 hrs by SRB method Cytotoxicity against human A549 cells after 72 hrs by SRB method	[PMID: 19324555]
A549	IC₅₀	51.64 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 25164762]
A549	IC₅₀	52 μM Compound: Fluorouracil	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 21774474]
A549	IC₅₀	54.8 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 22244588]
A549	IC₅₀	54.82 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
A549	IC₅₀	55.7 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29305189]
A549	IC₅₀	55.73 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 30007564]
A549	IC₅₀	56 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23356786]
A549	IC₅₀	6.6 μM Compound: 5-Fu	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 34883453]
A549	IC₅₀	6.69 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human A549 cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
A549	IC₅₀	6.76 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 26595184]
A549	IC₅₀	6.8 μM Compound: 5-FU	Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay Cytotoxicity against human A549 cells measured after 72 hrs by MTT assay	[PMID: 27537924]
A549	IC₅₀	6.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs Antiproliferative activity against human A549 cells assessed as reduction in cell viability measured for 24 hrs	[PMID: 31945642]
A549	IC₅₀	66 μg/mL Compound: 5-FU	Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
A549	IC₅₀	69.07 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29958763]
A549	IC₅₀	7.1 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in viability after 48 hrs by SRB assay Cytotoxicity against human A549 cells assessed as reduction in viability after 48 hrs by SRB assay	[PMID: 31103402]
A549	IC₅₀	7.1 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay Antiproliferative activity against human A549 cells after 3 days by sulforhodamine B assay	[PMID: 30248657]
A549	IC₅₀	7.244 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 26301558]
A549	IC₅₀	7.51 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 25870131]
A549	IC₅₀	7.6 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human A549 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 37098306]
A549	IC₅₀	7.62 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
A549	IC₅₀	71.09 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 30142612]
A549	IC₅₀	78 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by XTT method Cytotoxicity against human A549 cells after 48 hrs by XTT method	[PMID: 20151671]
A549	IC₅₀	8.12 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 72 hrs by MTT assay Antiproliferative activity against human A549 cells after 72 hrs by MTT assay	[PMID: 35609396]
A549	IC₅₀	8.13 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation by CCK8 assay	[PMID: 25442303]
A549	IC₅₀	8.13 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human A549 cells after 48 hrs by CCK-8 assay	[PMID: 27542307]
A549	IC₅₀	8.13 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay Antiproliferative activity against human A549 cells after 48 hrs by CCK8 assay	[PMID: 26786698]
A549	IC₅₀	8.48 μM Compound: 5-FU	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 29133051]
A549	IC₅₀	8.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human A549 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
A549	IC₅₀	8.71 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 23685571]
A549	IC₅₀	8.83 μM Compound: 5-Fu	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 22687745]
A549	IC₅₀	8.9 μM Compound: 5-Fu	Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human A549 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
A549	IC₅₀	8.92 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells by MTT assay Antiproliferative activity against human A549 cells by MTT assay	[PMID: 24095094]
A549	IC₅₀	88.27 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 39163776]
A549	IC₅₀	88.9 μM Compound: 5-FU	Cytotoxicity against human A549 cells after 48 hrs by MTT assay Cytotoxicity against human A549 cells after 48 hrs by MTT assay	[PMID: 23067549]
A549	IC₅₀	9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay Antiproliferative activity against human A549 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
A549	IC₅₀	9.19 μM Compound: 5-Fluorouracil	Cytotoxicity against human A549 cells after 72 hrs by MTT assay Cytotoxicity against human A549 cells after 72 hrs by MTT assay	[PMID: 18440233]
A549	IC₅₀	9.2 μM Compound: 5-FU	Cytotoxicity against A549 cells after 48 hrs by MTT assay Cytotoxicity against A549 cells after 48 hrs by MTT assay	[PMID: 17604394]
A549	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human A549 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
A549	IC₅₀	> 100 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) A549 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) A549 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
A549	IC₅₀	> 100 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells after 48 hrs by MTT assay Antiproliferative activity against human A549 cells after 48 hrs by MTT assay	[PMID: 31057737]
A549	IC₅₀	> 20 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 38897138]
A549	IC₅₀	> 20 μM Compound: 5-fluorouracil	Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human A549 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21381696]
A549	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
A549	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
A549	IC₅₀	> 50 μM Compound: 5-Fu	Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human A549 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
A549/TR	IC₅₀	112.23 μM Compound: 5-FU	Cytotoxicity against human A549/TAX cells after 72 hrs by MTT assay Cytotoxicity against human A549/TAX cells after 72 hrs by MTT assay	[PMID: 30677614]
A549/TR	IC₅₀	84.28 μM Compound: 5-FU	Cytotoxicity against human A549/T cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human A549/T cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
ACHN	GI₅₀	0.27 μM Compound: 5-FU	Anticancer activity against human ACHN cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human ACHN cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
ACHN	GI₅₀	0.29 μM Compound: 5-FU	Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay Growth inhibition of human ACHN cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
ACHN	IC₅₀	0.27 μM Compound: 5-Fluorouracil	Cytotoxicity against human ACHN cells assessed as cell growth inhibition Cytotoxicity against human ACHN cells assessed as cell growth inhibition	[PMID: 36470105]
ACHN	IC₅₀	2.73 μM Compound: 5-fluorouracil	Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human ACHN cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
ACHN	IC₅₀	9.874 μg/mL Compound: 5-FU	Cytotoxicity against human ACHN cells after 24 hrs by MTT assay Cytotoxicity against human ACHN cells after 24 hrs by MTT assay	[PMID: 23548704]
AGS	EC₅₀	7.25 μM Compound: 5FU	Cytotoxicity against human AGS cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay Cytotoxicity against human AGS cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay	[PMID: 35939803]
AGS	GI₅₀	24.6 μM Compound: 5-FU	Antiproliferative activity against human AGS cells after 48 hrs by MTT assay Antiproliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 29040954]
AGS	GI₅₀	25 μM Compound: 5-Fu	Antiproliferative activity against human AGS cells after 48 hrs by MTT assay Antiproliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 28763647]
AGS	IC₅₀	11.04 μM Compound: 5-FU	Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human AGS cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
AGS	IC₅₀	23.24 μM Compound: 5-Fu	Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human AGS cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
AGS	IC₅₀	29.6 μM Compound: 5-FU	Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay Anti-proliferative activity against human AGS cells after 48 hrs by MTT assay	[PMID: 28947149]
AGS	IC₅₀	370 μM Compound: 5-FU	Cytotoxicity against AGS cells after 48 hrs by MTT assay Cytotoxicity against AGS cells after 48 hrs by MTT assay	[PMID: 17604394]
AGS	IC₅₀	58 μM Compound: 5-Fu	Cytotoxicity against human AGS cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human AGS cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 35191714]
AGS	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human AGS cells after 72 hrs by SRB method Cytotoxicity against human AGS cells after 72 hrs by SRB method	[PMID: 19324555]
ASPC1	IC₅₀	2.97 μM Compound: 5-FU	Cytotoxicity against human Aspc-1 cells by crystal violet staining Cytotoxicity against human Aspc-1 cells by crystal violet staining	[PMID: 20930123]
ASPC1	IC₅₀	98 μM Compound: 5-FU	Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human AsPC1 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
Astrocyte	IC₅₀	> 100 μM Compound: 5FU	Cytotoxicity against rat astrocytes Cytotoxicity against rat astrocytes	[PMID: 16970409]
B16	IC₅₀	1.19 μM Compound: 5-Fu	Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in mouse B16 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
B16	IC₅₀	10.52 μM Compound: 5-FU	Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay Antiproliferative activity against mouse B16 cells after 72 hrs by MTT assay	[PMID: 25529742]
B16	IC₅₀	12.62 μM Compound: 5-Fu	Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against mouse B16 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
B16	IC₅₀	17.85 μM Compound: 5-FU	Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay Antiproliferative activity against mouse B16 cells after 48 hrs by MTT assay	[PMID: 25164762]
B16	IC₅₀	2.6 μg/mL Compound: 5-FU	In vitro inhibitory activity against Mouse melanoma (B16) cell line. In vitro inhibitory activity against Mouse melanoma (B16) cell line.	[PMID: 1995905]
B16	IC₅₀	33 μM Compound: 5-fu	Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay	[PMID: 22304344]
B16	IC₅₀	4.2 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay Cytotoxicity against mouse B16 cells after 48 hrs by MTT assay	[PMID: 24332497]
B16	IC₅₀	7.64 μM Compound: 5-fluorouracil	Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay Cytotoxicity against mouse B16 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25506718]
B16	IC₅₀	8.73 μM Compound: 5-FU	Cytotoxicity against mouse B16 cells by MTT assay Cytotoxicity against mouse B16 cells by MTT assay	[PMID: 18644718]
B16-BL6	EC₅₀	1.23 μM Compound: 5-fluorouracil	Antiproliferative activity against mouse B16-BL6 cells after 72 hrs by MTT assay Antiproliferative activity against mouse B16-BL6 cells after 72 hrs by MTT assay	[PMID: 12027739]
B16-BL6	IC₅₀	0.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against mouse B16-BL6 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 11575942]
B16-BL6	IC₅₀	5.78 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay	[PMID: 18440233]
B16-BL6	IC₅₀	7.39 μM Compound: 5-Fluoro uracil	Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay Cytotoxicity against mouse B16-BL6 cells after 72 hrs by MTT assay	[PMID: 19689125]
B16-F10	IC₅₀	0.87 μM Compound: 5-Fu	Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Cytotoxicity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25180925]
B16-F10	IC₅₀	1.43 μM Compound: 5-Fu	Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Anticancer activity against mouse B16F10 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25655718]
B16-F10	IC₅₀	21.41 μM Compound: 5-Fluorouracil	Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay Anticancer activity against mouse B16F10 cells assessed as cell survival measured after 48 hrs by MTT assay	[PMID: 23312949]
B16-F10	IC₅₀	4 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse B16-F10 cells by MTT assay Cytotoxicity against mouse B16-F10 cells by MTT assay	[PMID: 29280630]
B16-F10	IC₅₀	6.29 μM Compound: 5-Fu	Antiproliferative activity against mouse B16/F10 cells after 72 hrs by MTT assay Antiproliferative activity against mouse B16/F10 cells after 72 hrs by MTT assay	[PMID: 29254641]
BALB/3T3	IC₅₀	3.23 μM Compound: FUra	Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against mouse BALB/3T3 cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
BGC-823	EC₅₀	17.37 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 21889345]
BGC-823	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human BGC823 after 24 hrs by MTT assay Cytotoxicity against human BGC823 after 24 hrs by MTT assay	[PMID: 19338315]
BGC-823	IC₅₀	0.7 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human BGC 823 cells by MTT assay Cytotoxicity against human BGC 823 cells by MTT assay	[PMID: 18205316]
BGC-823	IC₅₀	1.52 μM Compound: 5-Fluorouracil	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method Antiproliferative activity against human BGC823 cells after 48 hrs by MTT method	[PMID: 23018096]
BGC-823	IC₅₀	100.02 μM Compound: 5-FU	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 21962523]
BGC-823	IC₅₀	14.02 μM Compound: 5-Fu	Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
BGC-823	IC₅₀	15.4 μM Compound: 5-fluorouracil	Cytotoxicity against human BGC-823 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human BGC-823 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
BGC-823	IC₅₀	15.65 μM Compound: 5-Fu	Cytotoxicity against human BGC823 cells by MTT assay Cytotoxicity against human BGC823 cells by MTT assay	[PMID: 22801644]
BGC-823	IC₅₀	17.37 μM Compound: 5-Fluorouracil	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 28363444]
BGC-823	IC₅₀	24.8 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 30527868]
BGC-823	IC₅₀	3.84 μM Compound: 5-Fu	Cytotoxicity against human BGC823 cells by MTT method Cytotoxicity against human BGC823 cells by MTT method	[PMID: 23164710]
BGC-823	IC₅₀	31.16 μM Compound: fluorouracil	Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 17291040]
BGC-823	IC₅₀	34.8 μM Compound: 5-FU	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 30108895]
BGC-823	IC₅₀	34.8 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 28073676]
BGC-823	IC₅₀	35.6 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
BGC-823	IC₅₀	37 μM Compound: 5-Fu	Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay Antiproliferative activity against human BGC823 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
BGC-823	IC₅₀	4.5 μM Compound: 5-FU	Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay	[PMID: 22727445]
BGC-823	IC₅₀	5.4 μM Compound: 5-Fu	Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay	[PMID: 16499317]
BGC-823	IC₅₀	5.89 μM Compound: 5-Fu	Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
BGC-823	IC₅₀	6.9 μM Compound: 5-fluorouracil	Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human BGC-823 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 36893627]
BGC-823	IC₅₀	7.48 μM Compound: 5-FU	Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay Cytotoxicity against human BGC823 cells after 48 hrs by MTT assay	[PMID: 24286761]
BGC-823	IC₅₀	8.2 μg/mL Compound: 5-FU	Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay Cytotoxicity against human BGC823 cells after 72 hrs by MTT assay	[PMID: 22647218]
BGC-823	IC₅₀	8.82 μM Compound: 5-FU	Cytotoxicity against human BGC823 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human BGC823 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
BT-20	IC₅₀	47.3 μM Compound: 5FU	Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay Cytotoxicity against human BT20 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
BT-474	IC₅₀	72.9 μM Compound: 5-Fu	Cytotoxicity against human BT474 cells after 3 days by MTT assay Cytotoxicity against human BT474 cells after 3 days by MTT assay	[PMID: 22000925]
BT-549	GI₅₀	10.6 μM Compound: 5-FU	Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human BT549 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
BT-549	GI₅₀	10.6 μM Compound: 5-FU	Anticancer activity against human BT-549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human BT-549 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
BT-549	IC₅₀	10.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human BT-549 cells assessed as cell growth inhibition Cytotoxicity against human BT-549 cells assessed as cell growth inhibition	[PMID: 36470105]
BT-549	IC₅₀	19.82 μM Compound: 5-FU	Anticancer activity against human BT549 cells after 48 hrs by MTT assay Anticancer activity against human BT549 cells after 48 hrs by MTT assay	[PMID: 26413726]
BT-549	IC₅₀	19.82 μM Compound: 5-FU	Cytotoxicity against human BT549 cells after 48 hrs by MTT assay Cytotoxicity against human BT549 cells after 48 hrs by MTT assay	[PMID: 27397498]
BT-549	IC₅₀	98.24 μM Compound: Fluorouracil	Cytotoxicity against human BT549 cells after 48 hrs by MTT assay Cytotoxicity against human BT549 cells after 48 hrs by MTT assay	[PMID: 28789892]
BXPC-3	EC₅₀	0.14 μM Compound: 1; 5-FU	Antiproliferative activity against human BxPC-3 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay Antiproliferative activity against human BxPC-3 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay	[PMID: 34979089]
BXPC-3	GI₅₀	2.9 nM Compound: 5FU	Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay	[PMID: 23094992]
BXPC-3	GI₅₀	8.2 μM Compound: 5-Fu	Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay Growth inhibition of human BxPC3 cells after 48 hrs by SRB assay	[PMID: 22512908]
BXPC-3	IC₅₀	2.96 μM Compound: 5-Fu	Antiproliferative activity against human BXPC-3 cells incubated for 72 hrs by SRB assay Antiproliferative activity against human BXPC-3 cells incubated for 72 hrs by SRB assay	[PMID: 39054645]
Bcap37	IC₅₀	15.47 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 27133593]
Bcap37	IC₅₀	37.09 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
Bcap37	IC₅₀	47.09 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 26883148]
Bcap37	IC₅₀	47.1 μM Compound: 5FU	Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human Bcap37 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
Bcap37	IC₅₀	5.18 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 25554922]
Bcap37	IC₅₀	5.18 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
Bcap37	IC₅₀	5.33 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 22405648]
Bcap37	IC₅₀	5.58 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay Cytotoxicity against human Bcap37 cells after 48 hrs by MTT assay	[PMID: 24119869]
Bcap37	IC₅₀	5.58 μM Compound: 5-Fu	Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human Bcap37 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
Bel-7402	IC₅₀	0.54 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human Bel 7402 cells by MTT assay Cytotoxicity against human Bel 7402 cells by MTT assay	[PMID: 18205316]
Bel-7402	IC₅₀	10.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 26227777]
Bel-7402	IC₅₀	11.12 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 24819956]
Bel-7402	IC₅₀	11.78 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 25529742]
Bel-7402	IC₅₀	14.41 μM Compound: 5-FU	Cytotoxicity against human BEL-7402 cells by MTT assay Cytotoxicity against human BEL-7402 cells by MTT assay	[PMID: 18644718]
Bel-7402	IC₅₀	14.9 μM Compound: 5-Fu	Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 39106494]
Bel-7402	IC₅₀	14.91 μM Compound: 5-FU	Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human Bel-7402 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
Bel-7402	IC₅₀	15.6 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human Bel7402 cells incubated for 48 hrs by MTT assay	[PMID: 30851694]
Bel-7402	IC₅₀	17.59 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
Bel-7402	IC₅₀	18.49 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 29407983]
Bel-7402	IC₅₀	18.49 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 29524728]
Bel-7402	IC₅₀	18.65 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 30243153]
Bel-7402	IC₅₀	18.65 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
Bel-7402	IC₅₀	18.97 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 29635169]
Bel-7402	IC₅₀	19.84 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
Bel-7402	IC₅₀	19.91 μM Compound: 5-Fluorouracil	Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human Bel7402 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
Bel-7402	IC₅₀	2.23 μM Compound: 5-FU	Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human Bel7402 cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
Bel-7402	IC₅₀	2.25 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay	[PMID: 28165738]
Bel-7402	IC₅₀	20.93 μM Compound: 5-Fu	Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay	[PMID: 29174813]
Bel-7402	IC₅₀	21.3 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human Bel7402 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
Bel-7402	IC₅₀	21.8 μM Compound: fluorouracil	Cytotoxicity against human Bel7402 cells Cytotoxicity against human Bel7402 cells	[PMID: 21495659]
Bel-7402	IC₅₀	214.33 μM Compound: 5-FU	Antiproliferative activity in 5-FU resistant human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity in 5-FU resistant human Bel7402 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
Bel-7402	IC₅₀	23.21 μM Compound: fluorouracil	Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay Cytotoxicity against human Bel7402 cells after 48 hrs by MTT assay	[PMID: 17291040]
Bel-7402	IC₅₀	36.52 μM Compound: 5-FU	Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay	[PMID: 37659196]
Bel-7402	IC₅₀	4.2 μM Compound: 5-Fu	Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay Cytotoxicity against human BEL-7402 cells after 96 hrs by MTT assay	[PMID: 16499317]
Bel-7402	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human Bel7402 after 72 hrs by MTT assay Cytotoxicity against human Bel7402 after 72 hrs by MTT assay	[PMID: 19233650]
Bel-7402	IC₅₀	4.7 μM Compound: 5-Fluorouracil	Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay Antiproliferative activity against human Bel7402 cells after 24 hrs by MTT assay	[PMID: 19560842]
Bel-7402	IC₅₀	5.5 μM Compound: 5-fluorouracil	Cytotoxicity against human Bel7402 cells after 4 days by MTT assay Cytotoxicity against human Bel7402 cells after 4 days by MTT assay	[PMID: 24359303]
Bel-7402	IC₅₀	5.94 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay Antiproliferative activity against human Bel7402 cells after 72 hrs by CCK-8 assay	[PMID: 28301815]
Bel-7402	IC₅₀	53.33 μM Compound: 5-FU	Cytotoxicity against human Bel7402 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Bel7402 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
Bel-7402	IC₅₀	7.36 μM Compound: 5-FU	Antiproliferative activity against human Bel7402 incubated for 72 hrs by MTT assay Antiproliferative activity against human Bel7402 incubated for 72 hrs by MTT assay	[PMID: 31553932]
Bel-7402	IC₅₀	7.57 μM Compound: 5-FU	Antiproliferative activity in human Bel7402 cells after 72 hrs by MTT assay Antiproliferative activity in human Bel7402 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
Bel-7402	IC₅₀	8.3 μM Compound: 5-Fu	Antiproliferative activity against human Bel7402 cells by MTT assay Antiproliferative activity against human Bel7402 cells by MTT assay	[PMID: 24095094]
Bel-7402	IC₅₀	> 500 μM Compound: 5-FU	Cytotoxicity against human Bel7402 cells assessed as growth inhibition by MTT assay Cytotoxicity against human Bel7402 cells assessed as growth inhibition by MTT assay	[PMID: 24684840]
Bel-7402	IC₅₀	> 700 μM Compound: 5-FU	Cytotoxicity against 5-fluorouracil-resistant human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against 5-fluorouracil-resistant human Bel7402 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26320625]
Bel7402/5-FU	IC₅₀	38.24 μM Compound: 5-FU	Cytotoxicity against human Bel7402/5-FU cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Bel7402/5-FU cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
Bel7402/5-FU	IC₅₀	61.7 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU cells incubated for 48 hrs by MTT assay	[PMID: 30851694]
Bel7402/5-FU	IC₅₀	935.78 μM Compound: 5-FU	Cytotoxicity against human Bel7402/5-FU cells after 72 hrs by MTT assay Cytotoxicity against human Bel7402/5-FU cells after 72 hrs by MTT assay	[PMID: 30677614]
Bel7402/5-FU	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by CCK-8 assay	[PMID: 28301815]
Bel7402/5-FU	IC₅₀	> 400 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU incubated for 72 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU incubated for 72 hrs by MTT assay	[PMID: 31553932]
Bel7402/5-FU	IC₅₀	> 80 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay	[PMID: 29407983]
Bel7402/5-FU	IC₅₀	> 80 μM Compound: 5-FU	Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay Antiproliferative activity against human Bel7402/5-FU cells after 72 hrs by MTT assay	[PMID: 29524728]
C-33-A	IC₅₀	4.61 μM Compound: 5-FU	Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human C33A cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
C13	IC₅₀	12.1 μM Compound: 5FU	Cytotoxicity against human C13 cells after 72 hrs Cytotoxicity against human C13 cells after 72 hrs	[PMID: 30035541]
C13	IC₅₀	8.5 μM Compound: 1, 5-FU	Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay Growth inhibition of cDDP-resistant human C13 cells by crystal violet assay	[PMID: 23075414]
C170	IC₅₀	0.3 μg/mL Compound: 5-FU	Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro	[PMID: 8496926]
C170	IC₅₀	2 μM Compound: 5-FU	Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro Tested for cytotoxicity against C170 colorectal carcinoma cell line by [75Se]selenomethionine uptake assay, in vitro	[PMID: 8496926]
C6	IC₅₀	6.1 μM Compound: 5FU	Cytotoxicity against rat C6 glioma cell line Cytotoxicity against rat C6 glioma cell line	[PMID: 16970409]
CAKI-1	GI₅₀	0.07 μM Compound: 5-FU	Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human CAKI-1 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
CAKI-1	GI₅₀	0.07 μM Compound: 5-FU	Anticancer activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human CAKI-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
CAKI-1	IC₅₀	0.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human CAKI-1 cells assessed as cell growth inhibition Cytotoxicity against human CAKI-1 cells assessed as cell growth inhibition	[PMID: 36470105]
CAL-27	IC₅₀	0.5 μg/mL Compound: 5-FU	Antiproliferative activity against human CAL-27 cells assessed as cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human CAL-27 cells assessed as cell viability measured after 72 hrs by MTT assay	[PMID: 34463097]
CAMA-1	IC₅₀	1.28 μM Compound: 5FU	Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay Cytotoxicity against human CAMA1 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
CAPAN-1	IC₅₀	0.47 μM Compound: 5-fluorouracil	Antiproliferative activity against human Capan-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay Antiproliferative activity against human Capan-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay	[PMID: 32007666]
CCD-18Co	IC₅₀	9.26 μM Compound: 5-Fu	Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay Cytotoxicity against human CCD-18Co cells after 3 days by SRB assay	[PMID: 24704691]
CCD-18Co	IC₅₀	> 200 μM Compound: 5-FU	Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human CCD-18Co cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32203786]
CCD-841CoN	EC₅₀	218 μM Compound: 5FU	Cytotoxicity against human CCD-841CoN cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay Cytotoxicity against human CCD-841CoN cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay	[PMID: 35939803]
CCD-841CoN	GI₅₀	10.3 μM Compound: 5-FU	Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay Cytotoxicity against human CRL1790 cells assessed as reduction in cell viability after 48 hrs by sulforhodamine B assay	[PMID: 28716495]
CCD-841CoN	IC₅₀	18.7 μM Compound: 5-FU	Cytotoxicity against human CRL1790 cells assessed as inhibition of cell growth Cytotoxicity against human CRL1790 cells assessed as inhibition of cell growth	[PMID: 31864797]
CCD-841CoN	IC₅₀	35.7 μM Compound: 5-FU	Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay Antiproliferative activity against human CCD-841-CoN cells after 72 hrs by MTT assay	[PMID: 30037494]
CCD-841CoN	IC₅₀	> 25 μM Compound: 5-FU	Antiproliferative activity against human CRL1790 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay Antiproliferative activity against human CRL1790 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay	[PMID: 23305919]
CCRF-CEM	GI₅₀	9.79 μM Compound: 5-FU	Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay Growth inhibition of human CCRF-CEM cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
CCRF-CEM	GI₅₀	9.97 μM Compound: 5-FU	Anticancer activity against human CCRF-CEM cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human CCRF-CEM cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
CCRF-CEM	IC₅₀	0.95 μg/mL Compound: 5-FU	Concentration at 50 percent inhibition of cell growth against human leukemia CCRF CEM cell line in vitro Concentration at 50 percent inhibition of cell growth against human leukemia CCRF CEM cell line in vitro	10.1016/S0960-894X(01)81041-6
CCRF-CEM	IC₅₀	1.2 μg/mL Compound: 5-FU	Evaluated for the inhibition of tumor cell growth of Human T-Lymphocyte cells (CEM/0) Evaluated for the inhibition of tumor cell growth of Human T-Lymphocyte cells (CEM/0)	[PMID: 11123990]
CCRF-CEM	IC₅₀	12 μM Compound: 1, 5-FU	Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting Cytostatic activity against thymidine-kinase deficient human CEM cells after 72 hrs by cell counting	[PMID: 21892829]
CCRF-CEM	IC₅₀	125 μM Compound: 5-FU	Antiproliferative activity against human CEM cells after 72 hrs by MTT assay Antiproliferative activity against human CEM cells after 72 hrs by MTT assay	[PMID: 19743863]
CCRF-CEM	IC₅₀	14 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 3 days by coulter counter analysis Cytotoxicity against human CEM cells after 3 days by coulter counter analysis	[PMID: 21232828]
CCRF-CEM	IC₅₀	14 μM Compound: 5-FU	Cytostatic activity against human CEM cells after 3 days by coulter counting analysis Cytostatic activity against human CEM cells after 3 days by coulter counting analysis	[PMID: 21330014]
CCRF-CEM	IC₅₀	15 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay Cytotoxicity against human CEM cells after 48 hrs by trypan blue assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	18 μM Compound: 1, 5-FU	Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting Cytostatic activity against human CEM/0 cells after 72 hrs by cell counting	[PMID: 21892829]
CCRF-CEM	IC₅₀	18 μM Compound: 5-FU	Cytostatic activity against human CEM cells after 72 hrs by Coulter counting Cytostatic activity against human CEM cells after 72 hrs by Coulter counting	[PMID: 25435471]
CCRF-CEM	IC₅₀	18 μM Compound: 5-Fluorouracil	Cytostatic activity against human CEM cells after 3 days by coulter counter analysis Cytostatic activity against human CEM cells after 3 days by coulter counter analysis	[PMID: 22405290]
CCRF-CEM	IC₅₀	18 μM Compound: 5-Fluorouracil	Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method Cytostatic activity against human CEM cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method	[PMID: 24906510]
CCRF-CEM	IC₅₀	18 μM Compound: 5-Fluorouracil	Cytotoxicity against human CEM cells assessed as inhibition of cell proliferation Cytotoxicity against human CEM cells assessed as inhibition of cell proliferation	[PMID: 26001344]
CCRF-CEM	IC₅₀	18 μM Compound: 5-Fluorouracil	Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method Anti-proliferative activity against human CEM cells measured after 72 hrs by coulter counter method	[PMID: 27750154]
CCRF-CEM	IC₅₀	18 μM Compound: 5FU	Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay Cytotoxicity against human CCRF-CEM cells assessed as reduction in cell number after 72 hrs by cell counting assay	[PMID: 24631358]
CCRF-CEM	IC₅₀	18 μM Compound: F-Uracil	Cytostatic activity against human CEM cells Cytostatic activity against human CEM cells	[PMID: 21917363]
CCRF-CEM	IC₅₀	2 μM Compound: 5-FU	In vitro cytotoxic activity against CCRF-CEM human lymphoblastoid cells in culture. In vitro cytotoxic activity against CCRF-CEM human lymphoblastoid cells in culture.	10.1016/0960-894X(96)00451-9
CCRF-CEM	IC₅₀	2 μM Compound: 5-FU	Effect on CCRF-CEM cells in culture Effect on CCRF-CEM cells in culture	[PMID: 2362278]
CCRF-CEM	IC₅₀	2.1 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human acute lymphocytic leukemia (CCRF-CEM) cells In vitro inhibitory activity against growth of Human acute lymphocytic leukemia (CCRF-CEM) cells	[PMID: 1995901]
CCRF-CEM	IC₅₀	30 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 72 hrs by MTT assay Cytotoxicity against human CEM cells after 72 hrs by MTT assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	32 μM Compound: 5-Fluorouracil	Cytotoxicity against human CEM cells after 72 hrs by MTT assay Cytotoxicity against human CEM cells after 72 hrs by MTT assay	[PMID: 23535322]
CCRF-CEM	IC₅₀	33.1 μM Compound: 5-FU	Anticancer activity against human CCRF-CEM cells Anticancer activity against human CCRF-CEM cells	[PMID: 21449610]
CCRF-CEM	IC₅₀	40 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 48 hrs by MTT assay Cytotoxicity against human CEM cells after 48 hrs by MTT assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	40 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of cell growth of CCRF CEM leukemic cell lines in human. Concentration required for 50% inhibition of cell growth of CCRF CEM leukemic cell lines in human.	[PMID: 1992123]
CCRF-CEM	IC₅₀	40 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human T-cell acute lymphoblastoid leukemia (CCRF CEM) cell line. In vitro inhibitory activity against Human T-cell acute lymphoblastoid leukemia (CCRF CEM) cell line.	[PMID: 1995905]
CCRF-CEM	IC₅₀	40 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of human T-cell acute lymphoblastoid leukemic CCRFCEM cell lines. In vitro inhibitory effect on growth of human T-cell acute lymphoblastoid leukemic CCRFCEM cell lines.	[PMID: 3373480]
CCRF-CEM	IC₅₀	4 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human leukemia cell line CCRF CEM after 72 hr of incubation The compound was evaluated for antitumoral activity against human leukemia cell line CCRF CEM after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
CCRF-CEM	IC₅₀	8 μM Compound: 5-FU	Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay Cytotoxicity against human CEM cells after 72 hrs by trypan blue assay	[PMID: 21439690]
CCRF-CEM	IC₅₀	8.9 μM Compound: 5-Fluorouracil	Concentration required to inhibit 50% of cell growth on CEM lymphocytes. Concentration required to inhibit 50% of cell growth on CEM lymphocytes.	[PMID: 11052798]
CCRF-CEM	IC₅₀	9 μM Compound: 5-Fluorouracil	Cytostatic activity against human CEM cells Cytostatic activity against human CEM cells	[PMID: 17931862]
CCRF-CEM	IC₅₀	9.23 μM Compound: 5-FU	Antiproliferative activity against human CEM cells after 3 days by MTT assay Antiproliferative activity against human CEM cells after 3 days by MTT assay	[PMID: 18424155]
CCRF-CEM	IC₅₀	9.97 μM Compound: 5-Fluorouracil	Cytotoxicity against human CCRF-CEM cells assessed as cell growth inhibition Cytotoxicity against human CCRF-CEM cells assessed as cell growth inhibition	[PMID: 36470105]
CCRF-CEM	IC₅₀	90.5 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against CEM cells Tested in vitro for anticancer activity against CEM cells	[PMID: 10072683]
CCRF-CEM	IC₅₀	5.0 x 10^-6 M Compound: FUra	Concentration required for the 50% inhibition of growth of CCRF-CEM human leukemia cells in culture Concentration required for the 50% inhibition of growth of CCRF-CEM human leukemia cells in culture	[PMID: 7120290]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay	[PMID: 27875779]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay	[PMID: 28525845]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells after 72 hrs by MTT assay	[PMID: 29133046]
CFPAC-1	IC₅₀	0.14 μM Compound: 5-FU	Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human CFPAC-1 cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
CFPAC-1	IC₅₀	41.221 μM Compound: 5-Fluorouracil	Cytotoxicity against human CFPAC-1 cells incubated for 24 hrs by MTT assay Cytotoxicity against human CFPAC-1 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
CHO	IC₅₀	12 μg/mL Compound: 5-fluorouracil	Cytotoxicity against CHO cells by MTT assay Cytotoxicity against CHO cells by MTT assay	[PMID: 29280630]
CHO	IC₅₀	5 μM Compound: FU	Growth inhibitory activity against CHO cells in culture. Growth inhibitory activity against CHO cells in culture.	[PMID: 7853342]
CHO-FU	IC₅₀	100 μM Compound: FU	Growth inhibitory activity against CHO/FU cells in culture. Growth inhibitory activity against CHO/FU cells in culture.	[PMID: 7853342]
CNE	IC₅₀	15.07 μM Compound: 5-Fu	Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human CNE cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
CNE	IC₅₀	40.21 μM Compound: 5-FU	Cytotoxicity against human CNE cells after 48 hrs by MTT assay Cytotoxicity against human CNE cells after 48 hrs by MTT assay	[PMID: 24378217]
CNE	IC₅₀	45.1 μM Compound: 5-Fu	Cytotoxicity against human CNE cells after 48 hrs by MTT assay Cytotoxicity against human CNE cells after 48 hrs by MTT assay	[PMID: 24953029]
CNE-2	IC₅₀	13.1 μM Compound: 5-FU	Cytotoxicity against human CNE2 cells after 3 days by MTT assay Cytotoxicity against human CNE2 cells after 3 days by MTT assay	[PMID: 21144621]
CNE-2	IC₅₀	13.5 μM Compound: Fluorouracil	Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay Cytotoxicity against human CNE2 cells after 72 hrs ny MTT assay	[PMID: 22200404]
CNE-2	IC₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay Cytotoxicity against human CNE2 cells after 72 hrs by MTT assay	[PMID: 22749192]
CNE-2	IC₅₀	17.2 μM Compound: 5-FU	Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay Antiproliferative activity against human CNE2 cells after 72 hrs by MTT assay	[PMID: 22079378]
COLO 205	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
COLO 205	EC₅₀	38.06 μM Compound: 5-FU	Antiproliferative activity against human COLO205 cells after 24 hrs by MTT assay Antiproliferative activity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 25198997]
COLO 205	GI₅₀	0.15 μM Compound: 5-FU	Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
COLO 205	GI₅₀	0.15 μM Compound: 5-FU	Anticancer activity against human COLO 205 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human COLO 205 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
COLO 205	GI₅₀	2.8 μM Compound: 5FU	Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
COLO 205	IC₅₀	0.15 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO 205 cells assessed as cell growth inhibition Cytotoxicity against human COLO 205 cells assessed as cell growth inhibition	[PMID: 36470105]
COLO 205	IC₅₀	0.1 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human colon adenocarcinoma (COLO 205) cells. In vitro inhibitory activity against growth of Human colon adenocarcinoma (COLO 205) cells.	[PMID: 1995901]
COLO 205	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human COLO205 cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
COLO 205	IC₅₀	1.9 μM Compound: 5-F	Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 28254697]
COLO 205	IC₅₀	1.9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human COLO205 cells by MTT assay Antiproliferative activity against human COLO205 cells by MTT assay	[PMID: 29798826]
COLO 205	IC₅₀	11.63 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs Antiproliferative activity against p53 deficient human COLO205 cells after 72 hrs	[PMID: 18469809]
COLO 205	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
COLO 205	IC₅₀	2.9 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) COLO205 cells by SRB assay Cytotoxicity against Homo sapiens (human) COLO205 cells by SRB assay	10.1007/s00044-010-9500-5
COLO 205	IC₅₀	21 μM Compound: 5-FU	Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human COLO205 cells after 48 hrs by sulforhodamine B assay	[PMID: 19939522]
COLO 205	IC₅₀	27.7 μM Compound: 5-FU	Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 30 mins by SRB assay Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 30 mins by SRB assay	[PMID: 30114660]
COLO 205	IC₅₀	3.39 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human COLO205 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
COLO 205	IC₅₀	3.39 μM Compound: 5-fluorouracil	Cytotoxicity against human COLO205 cells Cytotoxicity against human COLO205 cells	[PMID: 16996657]
COLO 205	IC₅₀	32 μM Compound: 5-FU	Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay Cytotoxicity against human COLO 205 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay	[PMID: 38536967]
COLO 205	IC₅₀	4.03 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 23352638]
COLO 205	IC₅₀	4.17 μM Compound: 5-FU	Anticancer activity against human COLO205 cells Anticancer activity against human COLO205 cells	[PMID: 21449610]
COLO 205	IC₅₀	4.17 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO205 cells Cytotoxicity against human COLO205 cells	[PMID: 22409967]
COLO 205	IC₅₀	4.54 μM Compound: 5-Fu	Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
COLO 205	IC₅₀	4.562 μg/mL Compound: 5-FU	Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay Cytotoxicity against human COLO205 cells after 24 hrs by MTT assay	[PMID: 23548704]
COLO 205	IC₅₀	5.29 μM Compound: 5-FU	Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human COLO 205 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34170142]
COLO 205	IC₅₀	90 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient COLO205 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient COLO205 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
COLO 320	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human COLO320 cells after 48 hrs Antiproliferative activity against human COLO320 cells after 48 hrs	[PMID: 21458113]
COLO 320	IC₅₀	12.5 μM Compound: 5-FU	Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay Cytotoxicity against human COLO320 cells assessed as cell viability after 72 hrs by WST-1 assay	[PMID: 22955095]
COLO 320	IC₅₀	8.7 μM Compound: 5-FU	Antiproliferative activity against human COLO320 cells after 72 hrs Antiproliferative activity against human COLO320 cells after 72 hrs	[PMID: 21458113]
COLO 320DM	IC₅₀	1.1 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of COLO 320DM tumor cell line from colon. Compound was tested for its inhibitory effect on the growth of COLO 320DM tumor cell line from colon.	10.1016/0960-894X(96)00339-3
COLO 320DM	IC₅₀	2 μM Compound: 5-Fluorouracil	Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay Cytotoxicity against human COLO320DM cells after 48 hrs by MTT assay	[PMID: 23792352]
COLO357	IC₅₀	2.05 μM Compound: 5-FU	Cytotoxicity against human Colo-357 cells by crystal violet staining Cytotoxicity against human Colo-357 cells by crystal violet staining	[PMID: 20930123]
COS-1	IC₅₀	110 μM Compound: 5-FU	Cytotoxicity against african green monkey COS1 cells after 24 hrs by MTT assay Cytotoxicity against african green monkey COS1 cells after 24 hrs by MTT assay	[PMID: 23202484]
CT26	IC₅₀	59.23 μM Compound: 1; 5-FU	Growth inhibition of CT26 cells incubated for 1.5 hrs by MTT assay Growth inhibition of CT26 cells incubated for 1.5 hrs by MTT assay	[PMID: 38107178]
CT26.WT	IC₅₀	5 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse CT26.WT cells by MTT assay Cytotoxicity against mouse CT26.WT cells by MTT assay	[PMID: 29280630]
CWR22R	IC₅₀	18.31 μM Compound: 5-FU	Antiproliferative activity against human 22Rv1 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human 22Rv1 cells assessed as cell growth inhibition by MTT assay	[PMID: 34000484]
CWR22R	IC₅₀	3.83 μM Compound: 5-fluorouracil	Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human 22Rv1 cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
Ca9-22	CC₅₀	13 μM Compound: 5-FU	Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32795767]
Ca9-22	CC₅₀	262 μM Compound: 5-FU	Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human Ca9-22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31532650]
Caco-2	CC₅₀	384.4 μM Compound: 5-FU	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 17337193]
Caco-2	CC₅₀	384.4 μM Compound: 5-Fu	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 18037195]
Caco-2	CC₅₀	384.4 μM Compound: 5FU	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 17548129]
Caco-2	CC₅₀	384.4 μM Compound: 5FU	Cytotoxicity against human Caco-2 cells after 72 hrs Cytotoxicity against human Caco-2 cells after 72 hrs	[PMID: 17555969]
Caco-2	GI₅₀	2.2 μM Compound: 5-FU	Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control Antiproliferative activity against human Caco2 cells after 72 hrs by MTT-based Mosmann assay relative to control	[PMID: 26539626]
Caco-2	GI₅₀	3.3 μM Compound: 5-FU	Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay Growth inhibition of human Caco2 cells measured after 72 hrs by MTT assay	[PMID: 27504537]
Caco-2	IC₅₀	0.266 μM Compound: 5-FU	Anticancer activity against human Caco-2 cells incubated for 72 hrs by MTT assay Anticancer activity against human Caco-2 cells incubated for 72 hrs by MTT assay	[PMID: 36921275]
Caco-2	IC₅₀	0.277 μM Compound: 5-FU	Cytotoxicity against human Caco-2 cells by MTT assay Cytotoxicity against human Caco-2 cells by MTT assay	[PMID: 36335743]
Caco-2	IC₅₀	1.5 μM Compound: 5-FU	Growth inhibition of human Caco-2 cells after 10 days Growth inhibition of human Caco-2 cells after 10 days	[PMID: 17337193]
Caco-2	IC₅₀	1.5 μM Compound: 5-Fu	Growth inhibition of human Caco-2 cells after 10 days Growth inhibition of human Caco-2 cells after 10 days	[PMID: 18037195]
Caco-2	IC₅₀	1.5 μM Compound: 5FU	Growth inhibition of human Caco-2 cells Growth inhibition of human Caco-2 cells	[PMID: 17548129]
Caco-2	IC₅₀	1.5 μM Compound: 5FU	Growth inhibition of human Caco-2 cells after 10 days Growth inhibition of human Caco-2 cells after 10 days	[PMID: 17555969]
Caco-2	IC₅₀	10 μM Compound: 5-Fluorouracil	Cytotoxicity against human Caco2 cells Cytotoxicity against human Caco2 cells	[PMID: 31200236]
Caco-2	IC₅₀	21 μM Compound: 5-Fluorouracil	Cytotoxicity against Homo sapiens (human) Caco2 cells after 48 hr by SRB assay Cytotoxicity against Homo sapiens (human) Caco2 cells after 48 hr by SRB assay	10.1007/s00044-012-0424-0
Caco-2	IC₅₀	21 μM Compound: 5-Fluorouracil	Cytotoxicity against human Caco2 cells assessed as inhibition of cell proliferation after 48 hrs by sulforhodamine-B assay Cytotoxicity against human Caco2 cells assessed as inhibition of cell proliferation after 48 hrs by sulforhodamine-B assay	10.1039/C3MD00055A
Caco-2	IC₅₀	31 μM Compound: 5-FU	Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay Cytotoxicity against human Caco2 cells assessed as cell viability after 24 hrs by MTT assay	[PMID: 28463785]
Caco-2	IC₅₀	38.77 μM Compound: 5-FU	Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay Antiproliferative activity against human Caco2 cells after 72 hrs by MTT assay	[PMID: 29635169]
Caco-2	IC₅₀	4.75 μM Compound: 5-FU	Antiproliferative activity against human Caco-2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay Antiproliferative activity against human Caco-2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay	[PMID: 38626522]
Caco-2	IC₅₀	60 μM Compound: 5-Fluorouracil	Cytotoxicity in human Caco2 cells after 72 hrs by MTT assay Cytotoxicity in human Caco2 cells after 72 hrs by MTT assay	[PMID: 28793973]
Caco-2	IC₅₀	7.77 μM Compound: 5-FU	Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human Caco-2 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34170142]
Caco-2	IC₅₀	7.8 μM Compound: 5-fluorouracil	Cytotoxicity against human Caco2 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human Caco2 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
Calu-1	IC₅₀	> 3.3 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human epidermoid carcinoma (Calu-1) cells In vitro inhibitory activity against growth of Human epidermoid carcinoma (Calu-1) cells	[PMID: 1995901]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Growth inhibition of human prostate cancer cells after 48 hrs Growth inhibition of human prostate cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method Growth inhibition of human prostate cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human prostate cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human prostate cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay Cytotoxicity against human prostate cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs Cytotoxicity against human prostate cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-FU	Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay Growth inhibition of human prostate cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-fu	Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay Antitumor activity against human prostate cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	22.7 μM Compound: 5-fu	Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human prostate cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Growth inhibition of human renal cancer cells after 48 hrs Growth inhibition of human renal cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting Cytotoxicity against human renal cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method Growth inhibition of human renal cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human renal cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human renal cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay Cytotoxicity against human renal cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs Cytotoxicity against human renal cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-FU	Growth inhibition of human renal cancer cells after 48 hrs by SRB assay Growth inhibition of human renal cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-fu	Antitumor activity against human renal cancer cells after 48 hrs by SRB assay Antitumor activity against human renal cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	45.6 μM Compound: 5-fu	Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human renal cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	5.75 μM Compound: 5-fluorouracil	Cytotoxicity against human colon cancer cells Cytotoxicity against human colon cancer cells	[PMID: 17562365]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Growth inhibition of human ovarian cancer cells after 48 hrs Growth inhibition of human ovarian cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counting Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Growth inhibition of human ovarian cancer cells after 48 hrs by coulter counter method Growth inhibition of human ovarian cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human ovarian cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human ovarian cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells after 48 hrs by SRB assay Cytotoxicity against human ovarian cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Cytotoxicity against human ovarian cancer cells at 10 uM after 48 hrs Cytotoxicity against human ovarian cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-FU	Growth inhibition of human ovarian cancer cells after 48 hrs by SRB assay Growth inhibition of human ovarian cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-fu	Antitumor activity against human ovarian cancer cells after 48 hrs by SRB assay Antitumor activity against human ovarian cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	61.4 μM Compound: 5-fu	Antiproliferative activity against human ovarian cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human ovarian cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	72.07 μM Compound: 5-FU	Growth inhibition of human CNS cancer cells after 48 hrs Growth inhibition of human CNS cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counting Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Growth inhibition of human CNS cancer cells after 48 hrs by coulter counter method Growth inhibition of human CNS cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human CNS cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human CNS cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells after 48 hrs by SRB assay Cytotoxicity against human CNS cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Cytotoxicity against human CNS cancer cells at 10 uM after 48 hrs Cytotoxicity against human CNS cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-FU	Growth inhibition of human CNS cancer cells after 48 hrs by SRB assay Growth inhibition of human CNS cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-fu	Antitumor activity against human CNS cancer cells after 48 hrs by SRB assay Antitumor activity against human CNS cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	72.1 μM Compound: 5-fu	Antiproliferative activity against human CNS cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human CNS cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Growth inhibition of human breast cancer cells after 48 hrs Growth inhibition of human breast cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by coulter counting Cytotoxicity against human breast cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Growth inhibition of human breast cancer cells after 48 hrs by coulter counter method Growth inhibition of human breast cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human breast cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human breast cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells after 48 hrs by SRB assay Cytotoxicity against human breast cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Cytotoxicity against human breast cancer cells at 10 uM after 48 hrs Cytotoxicity against human breast cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-FU	Growth inhibition of human breast cancer cells after 48 hrs by SRB assay Growth inhibition of human breast cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-fu	Antitumor activity against human breast cancer cells after 48 hrs by SRB assay Antitumor activity against human breast cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	76.4 μM Compound: 5-fu	Antiproliferative activity against human breast cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human breast cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	8.37 μM Compound: 5-FU	Growth inhibition of human Colon cancer cells after 48 hrs Growth inhibition of human Colon cancer cells after 48 hrs	[PMID: 18950904]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting Cytotoxicity against human colon cancer cells after 48 hrs by coulter counting	[PMID: 22056277]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method Growth inhibition of human colon cancer cells after 48 hrs by coulter counter method	[PMID: 22119151]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human colon cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human colon cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay Cytotoxicity against human colon cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs Cytotoxicity against human colon cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-FU	Growth inhibition of human colon cancer cells after 48 hrs by SRB assay Growth inhibition of human colon cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-fu	Antitumor activity against human colon cancer cells after 48 hrs by SRB assay Antitumor activity against human colon cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	8.4 μM Compound: 5-fu	Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human colon cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by coulter counter analysis Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by SRB assay Cytotoxicity against human non-small cell lung cancer cells after 48 hrs by SRB assay	[PMID: 23994328]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human non-small cell lung cancer cells at 10 uM after 48 hrs Cytotoxicity against human non-small cell lung cancer cells at 10 uM after 48 hrs	[PMID: 24469112]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human non-small cell lung cancer cells after 48 hrs by SRB assay Growth inhibition of human non-small cell lung cancer cells after 48 hrs by SRB assay	[PMID: 27554444]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-fu	Antitumor activity against human non small cell lung cancer cells after 48 hrs by SRB assay Antitumor activity against human non small cell lung cancer cells after 48 hrs by SRB assay	[PMID: 20350811]
Cancer cell lines	GI₅₀	> 100 μM Compound: 5-fu	Antiproliferative activity against human non-small cell lung cancer cells after 48 hrs by cell counting analysis Antiproliferative activity against human non-small cell lung cancer cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Cancer cell lines	IC₅₀	2.3 μM Compound: 5-Florouracil	Anticancer activity against Homo sapiens (human) NCI lung cancer cell assessed as inhibition of cell proliferation after 24 hr by MTT assay Anticancer activity against Homo sapiens (human) NCI lung cancer cell assessed as inhibition of cell proliferation after 24 hr by MTT assay	10.1007/s00044-012-0260-2
Cancer cell lines	IC₅₀	3.6 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate TSU cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate TSU cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
Cancer cell lines	IC₅₀	6.4 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate PPC-1 cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate PPC-1 cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
Cancer cell lines	IC₅₀	9.6 μM Compound: 5-fluorouracil	Antiproliferative activity in MDA-MB 231 human breast cancer cells Antiproliferative activity in MDA-MB 231 human breast cancer cells	[PMID: 15658875]
Cancer cell lines	IC₅₀	6.8 x 10^-5 M Compound: 5-Fu	Inhibitory concentration against Human Gastric cancer cell (BGC) lines was determined. Inhibitory concentration against Human Gastric cancer cell (BGC) lines was determined.	[PMID: 11229742]
Capan-2	IC₅₀	54.247 μM Compound: 5-Fluorouracil	Cytotoxicity against human Capan2 cells incubated for 24 hrs by MTT assay Cytotoxicity against human Capan2 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
Colon 26	IC₅₀	3.87 μM Compound: 5-Fluorouracil	Dark toxicity against human Colon 26 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay Dark toxicity against human Colon 26 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay	[PMID: 36561065]
Colon 26	IC₅₀	4.1 μM Compound: 5-Fluorouracil	Phototoxicity against human Colon 26 cells assessed as inhibition of cell growth preincubated for 24 hrs followed by compound washout with replacement of fresh medium and irradiation with 50 W LED light by MTT assay Phototoxicity against human Colon 26 cells assessed as inhibition of cell growth preincubated for 24 hrs followed by compound washout with replacement of fresh medium and irradiation with 50 W LED light by MTT assay	[PMID: 36561065]
DAN-G	IC₅₀	4.38 μM Compound: 5-FU	Cytotoxicity against human DAN-G cells by crystal violet staining Cytotoxicity against human DAN-G cells by crystal violet staining	[PMID: 20930123]
DLD-1	EC₅₀	16.3 μM Compound: 5-FU	Antiproliferative activity against human DLD1 cells after 24 hrs by MTT assay Antiproliferative activity against human DLD1 cells after 24 hrs by MTT assay	[PMID: 25198997]
DLD-1	IC₅₀	11 μM Compound: 5-FU	Induction of apoptosis in human DLD-1 cells in presence of EGCG at 50 uM Induction of apoptosis in human DLD-1 cells in presence of EGCG at 50 uM	[PMID: 36780831]
DLD-1	IC₅₀	11.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human DLD-1 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human DLD-1 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
DLD-1	IC₅₀	150 μM Compound: 5-FU	Antiproliferative activity against human DLD-1 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay Antiproliferative activity against human DLD-1 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay	[PMID: 36780831]
DLD-1	IC₅₀	29.14 μM Compound: 5-Fu	Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay Cytotoxicity against human DLD1 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay	[PMID: 24583355]
DLD-1	IC₅₀	33 μM Compound: 5-FU	Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay	[PMID: 30037494]
DLD-1	IC₅₀	33 μM Compound: 5-FU	Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay Antiproliferative activity against human DLD1 cells after 72 hrs by MTT assay	[PMID: 30429977]
DLD-1	IC₅₀	4.16 μM Compound: 5-FU	Inhibition of human DLD-1 cell spheroids incubated for 7 days by luciferase based assay Inhibition of human DLD-1 cell spheroids incubated for 7 days by luciferase based assay	[PMID: 36780832]
DLD-1	IC₅₀	4.5 μM Compound: 5-FU	Growth inhibition of human DLD1 cells Growth inhibition of human DLD1 cells	[PMID: 17553685]
DLD-1	IC₅₀	6 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of DLD-1 tumor cell line from colon. Compound was tested for its inhibitory effect on the growth of DLD-1 tumor cell line from colon.	10.1016/0960-894X(96)00339-3
DLD-1	IC₅₀	7.38 μM Compound: 5-FU	Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay Cytotoxicity against human DLD1 cells after 96 hrs by MTT assay	[PMID: 15387639]
DMS-114	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human DMS114 cells after 48 hrs by SRB assay Growth inhibition of human DMS114 cells after 48 hrs by SRB assay	[PMID: 22512908]
DU-145	GI₅₀	0.36 μM Compound: 5-FU	Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human DU145 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
DU-145	GI₅₀	0.36 μM Compound: 5-FU	Anticancer activity against human DU-145 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human DU-145 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
DU-145	GI₅₀	15.4 μM Compound: 5FU	Cytotoxicity against human DU145 cells after 48 hrs Cytotoxicity against human DU145 cells after 48 hrs	[PMID: 18798609]
DU-145	GI₅₀	1 μg/mL Compound: 5FU	Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human DU145 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
DU-145	GI₅₀	20 nM Compound: 5FU	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 23094992]
DU-145	GI₅₀	5.3 μM Compound: 5FU	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 20356752]
DU-145	GI₅₀	5.82 μM Compound: 5-FU	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 28400235]
DU-145	GI₅₀	9.37 μM Compound: 5-Fu	Growth inhibition of human DU145 cells after 48 hrs by SRB assay Growth inhibition of human DU145 cells after 48 hrs by SRB assay	[PMID: 22512908]
DU-145	IC₅₀	0.36 μM Compound: 5-Fluorouracil	Cytotoxicity against human DU-145 cells assessed as cell growth inhibition Cytotoxicity against human DU-145 cells assessed as cell growth inhibition	[PMID: 36470105]
DU-145	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human DU145 cells after 24 hrs by MTT assay Cytotoxicity against human DU145 cells after 24 hrs by MTT assay	[PMID: 24060486]
DU-145	IC₅₀	1.5 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 24 hrs by MTT assay Cytotoxicity against human DU145 cells after 24 hrs by MTT assay	[PMID: 24835633]
DU-145	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
DU-145	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
DU-145	IC₅₀	1.9 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
DU-145	IC₅₀	11.9 μM Compound: 5-FU	Concentration required to inhibit proliferation of DU-145 prostate cancer cell lines Concentration required to inhibit proliferation of DU-145 prostate cancer cell lines	[PMID: 15341952]
DU-145	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate DU-145 cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate DU-145 cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
DU-145	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against prostate cancer DU-145 cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer DU-145 cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
DU-145	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer DU-145 cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer DU-145 cell line by sulforhodamine B assay	[PMID: 16005217]
DU-145	IC₅₀	12.32 μM Compound: 5-Fu	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 22687745]
DU-145	IC₅₀	2.18 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 28431881]
DU-145	IC₅₀	2.18 μM Compound: 5-FU	Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay Cytotoxicity in human DU145 cells incubated for 48 hrs by MTT assay	[PMID: 28923381]
DU-145	IC₅₀	2.19 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 72 hrs by MTT assay Cytotoxicity against human DU145 cells after 72 hrs by MTT assay	[PMID: 20494492]
DU-145	IC₅₀	2.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human DU145 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human DU145 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
DU-145	IC₅₀	2.95 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) DU145 cells by MTT assay Cytotoxicity against Homo sapiens (human) DU145 cells by MTT assay	10.1007/s00044-010-9395-1
DU-145	IC₅₀	2.95 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) DU145 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) DU145 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
DU-145	IC₅₀	24.2 μM Compound: 5 Fluorouracil	Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
DU-145	IC₅₀	25.3 μM Compound: 5-Fu	Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay	[PMID: 30527868]
DU-145	IC₅₀	26.1 μM Compound: 5-Fu	Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27561718]
DU-145	IC₅₀	3.3 μM Compound: Fluorouracil	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 21774474]
DU-145	IC₅₀	3.4 μM Compound: Fluorouracil	Cytotoxic activity against human DU145 cells Cytotoxic activity against human DU145 cells	[PMID: 24195466]
DU-145	IC₅₀	38 μM Compound: 5-Fu	Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
DU-145	IC₅₀	39.17 μM Compound: 5-FU	Anticancer activity against human DU145 cells after 48 hrs by MTT assay Anticancer activity against human DU145 cells after 48 hrs by MTT assay	[PMID: 26413726]
DU-145	IC₅₀	39.17 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 27397498]
DU-145	IC₅₀	39.17 μM Compound: 5-FU	Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human DU145 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
DU-145	IC₅₀	4.8 μM Compound: 5-fluorouracil	Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human DU145 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
DU-145	IC₅₀	40.58 μM Compound: 5-FU	Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human DU145 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
DU-145	IC₅₀	6.072 μM Compound: 5-Fluorouracil	Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay Antiproliferative activity against human DU145 cells after 48 hrs by MTT assay	[PMID: 26301558]
DU-145	IC₅₀	6.37 μM Compound: 5-FU	Cytotoxicity against human DU145 cells after 48 hrs by MTT assay Cytotoxicity against human DU145 cells after 48 hrs by MTT assay	[PMID: 25870131]
DU-145	IC₅₀	8.58 μM Compound: 5-Fu	Antiproliferative activity against human DU-145 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antiproliferative activity against human DU-145 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36931124]
DU-145	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human DU145 cells by MTT assay Cytotoxicity against human DU145 cells by MTT assay	[PMID: 21689869]
DU-145	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human DU145 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
E0771	IC₅₀	0.28 μM Compound: 5-Fu	Cytotoxicity against mouse E0771 cells after 3 days by SRB assay Cytotoxicity against mouse E0771 cells after 3 days by SRB assay	[PMID: 24704691]
EC9706	IC₅₀	0.32 μM Compound: 5-Fu	Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 23644193]
EC9706	IC₅₀	15.67 μM Compound: 5-Fu	Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay Cytotoxicity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 25707012]
EC9706	IC₅₀	2.45 μM Compound: 5-FU	Antiproliferative activity against human EC9706 assessed as reduction in cell proliferation incubated for 72 hrs by MTT assay Antiproliferative activity against human EC9706 assessed as reduction in cell proliferation incubated for 72 hrs by MTT assay	[PMID: 37859725]
EC9706	IC₅₀	20.3 μM Compound: 5-Fu	Antitumor activity against human EC9706 cells after 72 hrs by MTT assay Antitumor activity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 21486694]
EC9706	IC₅₀	23.26 μM Compound: 5-Fluorouracil	Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay	[PMID: 28119200]
EC9706	IC₅₀	4.7 μM Compound: 5-Fu	Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human EC9706 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
EC9706	IC₅₀	5.13 μM Compound: 5-Fu	Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay Antiproliferative activity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 29475156]
EC9706	IC₅₀	8.07 μM Compound: 5-Fu	Anticancer activity against human EC9706 cells after 72 hrs by MTT assay Anticancer activity against human EC9706 cells after 72 hrs by MTT assay	[PMID: 25001482]
EC9706	IC₅₀	9.45 μM Compound: 5-Fu	Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay Antiproliferative activity against human EC9706 cells after 48 hrs by MTT assay	[PMID: 24835817]
EKVX	GI₅₀	61.8 μM Compound: 5-FU	Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay Growth inhibition of human EKVX cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
ES-2	IC₅₀	25.92 μM Compound: 5-FU	Antiproliferative activity against human ES2 cells Antiproliferative activity against human ES2 cells	[PMID: 38716896]
Ehrlich	CC₅₀	37.36 μM Compound: 5-FU	Cytotoxicity against mouse EAC cell assessed as reduction in cell viability incubated for 3 hrs by tryphan blue dye based assay Cytotoxicity against mouse EAC cell assessed as reduction in cell viability incubated for 3 hrs by tryphan blue dye based assay	[PMID: 33540356]
Ehrlich	CC₅₀	90.55 μM Compound: 5-FU	Growth inhibition of EAC cells after 3 hrs Growth inhibition of EAC cells after 3 hrs	[PMID: 17239491]
Ehrlich	ED₅₀	38.6 μg Compound: 5-FU	Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis	[PMID: 23022735]
Ehrlich	ED₅₀	58 μL Compound: 5FU	Antitumor activity against mouse EAC cells tansplanted in Swiss albino mouse assessed as dead cells at 50 to 250 mg/kg/day, ip by tyrpan blue assay Antitumor activity against mouse EAC cells tansplanted in Swiss albino mouse assessed as dead cells at 50 to 250 mg/kg/day, ip by tyrpan blue assay	[PMID: 19527933]
Ehrlich	ED₅₀	63 μg/cm³ Compound: 5-FU	In vitro antitumor activity against Mus musculus (mouse) Ehrlich ascites cell assessed as dead tumor cells by trypan blue exclusion test In vitro antitumor activity against Mus musculus (mouse) Ehrlich ascites cell assessed as dead tumor cells by trypan blue exclusion test	10.1007/s00044-012-0336-z
Ehrlich	ED₅₀	96.3 mM Compound: 5-flu	Cytotoxicity against Mus musculus (mouse) EAC assessed as cell viability by trypan blue exclusion assay Cytotoxicity against Mus musculus (mouse) EAC assessed as cell viability by trypan blue exclusion assay	10.1007/s00044-009-9199-3
Ehrlich	IC₅₀	0.38 μM Compound: 5-FU	Antitumor activity against mouse EAC cells by trypan blue exclusion assay Antitumor activity against mouse EAC cells by trypan blue exclusion assay	10.1007/s00044-013-0859-y
Ehrlich	IC₅₀	0.38 μM Compound: 5-fluorouracil	Anticancer activity against mouse EAC cells assessed as reduction in cell viability Anticancer activity against mouse EAC cells assessed as reduction in cell viability	[PMID: 33276991]
Ehrlich	IC₅₀	1.5 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells assessed as cell viability using trypan blue staining after 2 hrs by hemocytometer analysis Cytotoxicity against mouse EAC cells assessed as cell viability using trypan blue staining after 2 hrs by hemocytometer analysis	[PMID: 21353349]
Ehrlich	IC₅₀	14.3 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay Cytotoxicity against mouse EAC cells after 48 hrs by MTT assay	[PMID: 24534537]
Ehrlich	IC₅₀	14.6 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue dye exclusion method	[PMID: 25261825]
Ehrlich	IC₅₀	15.4 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay	[PMID: 25261825]
Ehrlich	IC₅₀	16.3 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay Cytotoxicity against mouse EAC cells after 48 hrs by LDH release assay	[PMID: 24534537]
Ehrlich	IC₅₀	16.3 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by MTT method Cytotoxicity against mouse EAC cells after 48 hrs by MTT method	[PMID: 25261825]
Ehrlich	IC₅₀	16.4 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay Cytotoxicity against mouse EAC cells after 48 hrs by trypan blue exclusion assay	[PMID: 24534537]
Ehrlich	IC₅₀	9.2 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
Ehrlich	IC₅₀	9.6 μM Compound: 5-fluorouracil	Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against mouse EAC cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
Ehrlich	IC₅₀	97.3 μg Compound: 5-FU	Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis Cytotoxicity against mouse EAC after 2 hrs by trypan blue staining based hemocytometer analysis	[PMID: 23022735]
FM3A	IC₅₀	0.02 μg/mL Compound: 5-FU	Evaluated for the inhibition of tumor cell growth of murine mammary carcinoma malignant tumor cell line (FM3A/0) Evaluated for the inhibition of tumor cell growth of murine mammary carcinoma malignant tumor cell line (FM3A/0)	[PMID: 11123990]
FM3A	IC₅₀	0.18 μM Compound: 5-FU	Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis Cytostatic activity against mouse FM3A cells after 2 days by coulter counting analysis	[PMID: 21330014]
Fibroblast	IC₅₀	11 μM Compound: 5-FU	Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test	[PMID: 21530016]
Fibroblast	IC₅₀	> 50 μM Compound: 5-FU	Cytotoxicity against human skin fibroblast cells incubated for 72 hrs by MTT assay Cytotoxicity against human skin fibroblast cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
G-292	IC₅₀	> 3.3 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human osteogenic sarcoma (G-292) cells In vitro inhibitory activity against growth of Human osteogenic sarcoma (G-292) cells	[PMID: 1995901]
GES1	IC₅₀	10.21 μM Compound: 5-FU	Cytotoxicity against human GES1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
GES1	IC₅₀	12.51 μM Compound: 5-Fu	Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay Antiproliferative activity against human GES-1 cells after 72 hrs by MTT assay	[PMID: 29635165]
GES1	IC₅₀	12.51 μM Compound: 5-Fu	Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human GES-1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
GES1	IC₅₀	13.75 μM Compound: 5-FU	Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human GES-1 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
GES1	IC₅₀	19.27 μM Compound: 5-FU	Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 34302974]
GES1	IC₅₀	2.37 μM Compound: 5-Fu	Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
GES1	IC₅₀	2.45 μM Compound: 5-Fu	Antiproliferative activity against human GES1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human GES1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
GES1	IC₅₀	3.69 μM Compound: 5-FU	Antiproliferative activity against human GES-1 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human GES-1 cells incubated for 72 hrs by MTT assay	[PMID: 31404863]
GES1	IC₅₀	30.9 μM Compound: 5-Fu	Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay Cytotoxicity against human GES-1 cells after 48 hrs by MTT assay	[PMID: 25462264]
GES1	IC₅₀	38.5 μM Compound: 5-Fu	Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
GES1	IC₅₀	49.6 μM Compound: 5-FU	Antiproliferative activity against human GES1 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human GES1 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 35286954]
GES1	IC₅₀	7.22 μM Compound: 5-Fu	Cytotoxicity against human GES-1 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human GES-1 cells assessed as cell growth inhibition after 72 hrs by MTT assay	10.1039/C6MD00169F
GES1	IC₅₀	78.4 μM Compound: 5-FU	Toxicity in human GES1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Toxicity in human GES1 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
GES1	IC₅₀	8.59 μM Compound: 5-FU	Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human GES-1 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759876]
GES1	IC₅₀	9.02 μM Compound: 5-FU	Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay Antiproliferative activity against human GES-1 cells after 48 hrs by MTT assay	[PMID: 28863355]
GES1	IC₅₀	> 100 μM Compound: 5-Fu	Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human GES1 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 35191714]
H4	CC₅₀	10 μM Compound: 5-Fu	Tumor selectivity index, ratio of CC50 for human H4 cells to CC50 for human Caco-2 cells Tumor selectivity index, ratio of CC50 for human H4 cells to CC50 for human Caco-2 cells	[PMID: 18037195]
H4	CC₅₀	3843.8 μM Compound: 5-FU	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 17337193]
H4	CC₅₀	3843.8 μM Compound: 5-Fu	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 18037195]
H4	CC₅₀	3843.8 μM Compound: 5FU	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 17548129]
H4	CC₅₀	3843.8 μM Compound: 5FU	Cytotoxicity against human H4 cells after 72 hrs Cytotoxicity against human H4 cells after 72 hrs	[PMID: 17555969]
H4	CC₅₀	83.4 μM Compound: 5-Fu	Tumor selectivity index, ratio of CC50 for human H4 cells to CC50 for human melanoma cells Tumor selectivity index, ratio of CC50 for human H4 cells to CC50 for human melanoma cells	[PMID: 18037195]
H69AR	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human H69AR cells after 48 hrs by SRB assay Growth inhibition of human H69AR cells after 48 hrs by SRB assay	[PMID: 22512908]
HBL-100	GI₅₀	4.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HBL-100 cells assessed as reduction in cell growth Antiproliferative activity against human HBL-100 cells assessed as reduction in cell growth	[PMID: 34847410]
HBL-100	GI₅₀	5.5 μM Compound: 5-FU	Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HBL100 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
HBL-100	GI₅₀	5.5 μM Compound: 5-FU	Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay	[PMID: 28728108]
HBL-100	GI₅₀	5.5 μM Compound: 5-FU	Antiproliferative activity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human HBL100 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
HBL-100	GI₅₀	5.5 μM Compound: 5-FU	Growth inhibition of human HBL-100 cells measured after 48 hrs by SRB colorimetric assay Growth inhibition of human HBL-100 cells measured after 48 hrs by SRB colorimetric assay	[PMID: 37137247]
HBL-100	GI₅₀	5.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HBL100 cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
HBL-100	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HBL100 cells by MTT assay Antiproliferative activity against human HBL100 cells by MTT assay	[PMID: 31546197]
HCC 2998	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCC 2998	GI₅₀	0.05 μM Compound: 5-FU	Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCC2998 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HCC 2998	GI₅₀	0.05 μM Compound: 5-FU	Anticancer activity against human HCC 2998 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HCC 2998 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HCC 2998	IC₅₀	0.05 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCC 2998 cells assessed as cell growth inhibition Cytotoxicity against human HCC 2998 cells assessed as cell growth inhibition	[PMID: 36470105]
HCC 2998	IC₅₀	12.6 μM Compound: 5-FU	Cytotoxicity against human HCC 2998 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay Cytotoxicity against human HCC 2998 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay	[PMID: 35182815]
HCC 2998	IC₅₀	13.5 μM Compound: 5-FU	Anticancer activity against human HCC2998 cells Anticancer activity against human HCC2998 cells	[PMID: 21449610]
HCC 2998	IC₅₀	13.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCC2998 cells Cytotoxicity against human HCC2998 cells	[PMID: 22409967]
HCC 2998	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCC2998 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCC 2998	IC₅₀	5.75 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human HCC2998 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
HCC 2998	IC₅₀	5.75 μM Compound: 5-fluorouracil	Cytotoxicity against human HCC2998 cells Cytotoxicity against human HCC2998 cells	[PMID: 16996657]
HCC1937	IC₅₀	25.94 μM Compound: 5-FU	Antitumor activity against human HCC1937 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human HCC1937 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
HCCLM3	IC₅₀	1.84 mM Compound: 5-FU	Antiproliferative activity against human HCCLM3 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Antiproliferative activity against human HCCLM3 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 28073674]
HCCLM9	IC₅₀	27.21 μM Compound: 5-FU	Antiproliferative activity against human HCCLM9 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human HCCLM9 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 37182331]
HCT-116	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-116	EC₅₀	0.5 μM Compound: 1; 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability measured after 5 days by PrestoBlue reagent based assay	[PMID: 34979089]
HCT-116	EC₅₀	> 1000 μM Compound: 5-FU	Reversal of 5-FU resistance against human HCT-116 cells overexpressing DPD assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay Reversal of 5-FU resistance against human HCT-116 cells overexpressing DPD assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay	[PMID: 34411894]
HCT-116	EC₅₀	> 1000 μM Compound: 5-FU	Antiproliferative activity against 5-FU resistant DPD expressed human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against 5-FU resistant DPD expressed human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34688013]
HCT-116	EC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 25198997]
HCT-116	ED₅₀	0.48 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HCT116 cells by MTT assay Cytotoxicity against human HCT116 cells by MTT assay	[PMID: 11908984]
HCT-116	GI₅₀	0.22 μM Compound: 5-FU	Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HCT-116	GI₅₀	0.22 μM Compound: 5-FU	Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HCT-116	GI₅₀	5.47 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 28716495]
HCT-116	GI₅₀	8.8 nM Compound: 5FU	Growth inhibition of human HCT116 cells after 48 hrs by SRB assay Growth inhibition of human HCT116 cells after 48 hrs by SRB assay	[PMID: 23094992]
HCT-116	GI₅₀	9.51 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay Cytotoxicity against human HCT116 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
HCT-116	GI₅₀	9.9 μM Compound: 5-Fu	Growth inhibition of human HCT116 cells after 48 hrs by SRB assay Growth inhibition of human HCT116 cells after 48 hrs by SRB assay	[PMID: 22512908]
HCT-116	GI₅₀	> 10 μM Compound: 4; 5-FU	Antiproliferative activity against human HCT-116 cells measured after 48 hrs by SRB assay Antiproliferative activity against human HCT-116 cells measured after 48 hrs by SRB assay	[PMID: 32683166]
HCT-116	IC₅₀	0.041 mM Compound: 5-Fluorouracil	Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human HCT116 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
HCT-116	IC₅₀	0.0462 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 72 hr by MTT assay	10.1007/s00044-012-0181-0
HCT-116	IC₅₀	0.22 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition	[PMID: 36470105]
HCT-116	IC₅₀	0.5 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay Cytotoxicity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 25066282]
HCT-116	IC₅₀	0.54 μM Compound: 5-fluorouracil	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability by SRB assay	[PMID: 30660827]
HCT-116	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-116	IC₅₀	1.93 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HCT116 cells by MTT assay Cytotoxicity against Homo sapiens (human) HCT116 cells by MTT assay	10.1007/s00044-010-9395-1
HCT-116	IC₅₀	1.93 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
HCT-116	IC₅₀	1.93 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 20494492]
HCT-116	IC₅₀	10.05 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 24953029]
HCT-116	IC₅₀	10.1 μM Compound: 5-FU	Synergistic antitumor activity against siRNA-mediated luciferase knockout human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs (Rvb = 13.8 microM) Synergistic antitumor activity against siRNA-mediated luciferase knockout human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs (Rvb = 13.8 microM)	[PMID: 23814490]
HCT-116	IC₅₀	10.54 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24819956]
HCT-116	IC₅₀	10.81 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
HCT-116	IC₅₀	11.29 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 29316536]
HCT-116	IC₅₀	11.56 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 30318440]
HCT-116	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human HCT116 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
HCT-116	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay	[PMID: 37243616]
HCT-116	IC₅₀	12.31 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
HCT-116	IC₅₀	13 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
HCT-116	IC₅₀	13.01 μM Compound: 1; 5-FU	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 1.5 hrs by CCK-8 assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 1.5 hrs by CCK-8 assay	[PMID: 38107178]
HCT-116	IC₅₀	13.8 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32682200]
HCT-116	IC₅₀	13.89 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by SRB method Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by SRB method	[PMID: 39054645]
HCT-116	IC₅₀	13.9 μM Compound: 1; 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay	[PMID: 33819035]
HCT-116	IC₅₀	14.29 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 37360398]
HCT-116	IC₅₀	14.43 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38677112]
HCT-116	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-116	IC₅₀	14.9 μM Compound: 1; 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 33819035]
HCT-116	IC₅₀	15.38 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
HCT-116	IC₅₀	15.52 μM Compound: 5-FU	Cytotoxicity against human HCT116 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
HCT-116	IC₅₀	16.58 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 37343499]
HCT-116	IC₅₀	16.72 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 38107169]
HCT-116	IC₅₀	17.01 μM Compound: 5-Fu	Cytotoxic activity against human HCT116 cells Cytotoxic activity against human HCT116 cells	[PMID: 28697923]
HCT-116	IC₅₀	17.25 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 29486954]
HCT-116	IC₅₀	17.3 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 31200236]
HCT-116	IC₅₀	18.4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
HCT-116	IC₅₀	18.4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 30108969]
HCT-116	IC₅₀	18.7 μM Compound: 5FU	Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HCT116 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HCT-116	IC₅₀	19.2 μM Compound: 5-FU	Anticancer activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay Anticancer activity against Homo sapiens (human) HCT116 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay	10.1007/s00044-012-0240-6
HCT-116	IC₅₀	19.2 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 48 hr by MTT assay Cytotoxicity against Homo sapiens (human) HCT116 cells assessed as growth inhibition after 48 hr by MTT assay	10.1007/s00044-012-0461-8
HCT-116	IC₅₀	19.27 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay	[PMID: 34715305]
HCT-116	IC₅₀	19.7 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by MTT assay	[PMID: 39045852]
HCT-116	IC₅₀	2 mM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27847140]
HCT-116	IC₅₀	2.04 μM Compound: 5-fluorouracil	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 16996657]
HCT-116	IC₅₀	2.3 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 26854375]
HCT-116	IC₅₀	2.5 μM Compound: 5-FU	Growth inhibition of human HCT116 cells after 72 hrs by MTS assay Growth inhibition of human HCT116 cells after 72 hrs by MTS assay	[PMID: 27704811]
HCT-116	IC₅₀	2.6 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 19743863]
HCT-116	IC₅₀	2.8 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs Antiproliferative activity against human HCT116 cells after 72 hrs	[PMID: 17548198]
HCT-116	IC₅₀	20.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 31471102]
HCT-116	IC₅₀	201 μg/mL Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
HCT-116	IC₅₀	21.54 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36269639]
HCT-116	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 24565905]
HCT-116	IC₅₀	24.58 μM Compound: 5-FU	Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
HCT-116	IC₅₀	24.8 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
HCT-116	IC₅₀	24.8 μM Compound: 5-Fu	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability by MTS assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability by MTS assay	[PMID: 38107170]
HCT-116	IC₅₀	26.14 μM Compound: 5-Fu	Anticancer activity against human HCT116 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against human HCT116 cells expressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
HCT-116	IC₅₀	26.2 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28400238]
HCT-116	IC₅₀	26042.5 x 10^-3 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 32203786]
HCT-116	IC₅₀	27.76 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 23558238]
HCT-116	IC₅₀	27.76 μM Compound: 5-Fu	Growth inhibition against human HCT116 cells after 48 hrs by MTT assay Growth inhibition against human HCT116 cells after 48 hrs by MTT assay	[PMID: 23999046]
HCT-116	IC₅₀	27.8 μM Compound: 5-FU	Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 26922233]
HCT-116	IC₅₀	29.2 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28073676]
HCT-116	IC₅₀	29.5 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 29232583]
HCT-116	IC₅₀	29.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 27503679]
HCT-116	IC₅₀	29.58 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
HCT-116	IC₅₀	29.6 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells incubated for 24 hrs by MTT assay Antiproliferative activity against human HCT-116 cells incubated for 24 hrs by MTT assay	[PMID: 39045852]
HCT-116	IC₅₀	3.03 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay Cytotoxicity against human HCT116 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20163895]
HCT-116	IC₅₀	3.2 μM Compound: 5-FU	Synergistic antitumor activity against siRNA-mediated Pim-1 knockout human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs (Rvb = 13.8 microM) Synergistic antitumor activity against siRNA-mediated Pim-1 knockout human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs (Rvb = 13.8 microM)	[PMID: 23814490]
HCT-116	IC₅₀	3.24 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 23685571]
HCT-116	IC₅₀	3.56 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay Antiproliferative activity against human HCT116 cells assessed as inhibition cell proliferation after 48 hrs by Sulforhodamine B assay	[PMID: 23305919]
HCT-116	IC₅₀	30.72 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth	[PMID: 36089111]
HCT-116	IC₅₀	300 μM Compound: 5-FU	Growth inhibition in HCT116 cells assessed as inhibition of [3H]thymidine incorporation Growth inhibition in HCT116 cells assessed as inhibition of [3H]thymidine incorporation	[PMID: 17411027]
HCT-116	IC₅₀	31.72 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 22483608]
HCT-116	IC₅₀	32.26 μM Compound: 5-FU	Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
HCT-116	IC₅₀	36.2 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
HCT-116	IC₅₀	36.4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 23067549]
HCT-116	IC₅₀	37.22 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
HCT-116	IC₅₀	37.6 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 30108895]
HCT-116	IC₅₀	38.3 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HCT-116	IC₅₀	38.3 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 28110871]
HCT-116	IC₅₀	38.3 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 30142612]
HCT-116	IC₅₀	4 μM Compound: 5-FU	Antitumor activity against human HCT116 cells after 24 hrs by MTT assay Antitumor activity against human HCT116 cells after 24 hrs by MTT assay	[PMID: 20211564]
HCT-116	IC₅₀	4 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 22130132]
HCT-116	IC₅₀	4 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay Antiproliferative activity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 29326016]
HCT-116	IC₅₀	4 μM Compound: 5-Fluorouracil	Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay Cytostatic activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 22405290]
HCT-116	IC₅₀	4 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
HCT-116	IC₅₀	4.02 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth Cytotoxicity against human HCT116 cells assessed as inhibition of cell growth	[PMID: 31864797]
HCT-116	IC₅₀	4.1 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay	[PMID: 38688437]
HCT-116	IC₅₀	4.16 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 28458133]
HCT-116	IC₅₀	4.3 μM Compound: 5-FU	Antiproliferative activity in human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity in human HCT116 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
HCT-116	IC₅₀	4.3 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells harboring p53 knock out gene assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-116 cells harboring p53 knock out gene assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-116	IC₅₀	4.42 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells expressing wild type p53 incubated for 72 hrs by MTS assay Cytotoxicity against human HCT116 cells expressing wild type p53 incubated for 72 hrs by MTS assay	[PMID: 31158748]
HCT-116	IC₅₀	4.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human HCT116 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 26222449]
HCT-116	IC₅₀	4.52 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT116 cells after 48 hrs by sulforhodamine B assay	[PMID: 23644215]
HCT-116	IC₅₀	4.6 μM Compound: 5-FU	Anticancer activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Anticancer activity against human HCT-116 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33940466]
HCT-116	IC₅₀	4.69 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells deficient in p53 incubated for 72 hrs by MTS assay Cytotoxicity against human HCT116 cells deficient in p53 incubated for 72 hrs by MTS assay	[PMID: 31158748]
HCT-116	IC₅₀	4.89 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
HCT-116	IC₅₀	4.8 μg/mL Compound: 5-Fu	Anticancer activity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
HCT-116	IC₅₀	4.9 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
HCT-116	IC₅₀	4.93 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay	[PMID: 15387639]
HCT-116	IC₅₀	40 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell growth incubated for 24 hrs by MTT assay	[PMID: 36780831]
HCT-116	IC₅₀	41.9 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28532669]
HCT-116	IC₅₀	44.06 μM Compound: 2; 5-FU	Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
HCT-116	IC₅₀	5 μM Compound: 5-FU	Induction of apoptosis in human HCT-116 cells in presence of EGCG at 50 uM Induction of apoptosis in human HCT-116 cells in presence of EGCG at 50 uM	[PMID: 36780831]
HCT-116	IC₅₀	5.2 μg/mL Compound: 5-Fu	Cytotoxicity against human HCT-116 cells Cytotoxicity against human HCT-116 cells	[PMID: 31761383]
HCT-116	IC₅₀	5.3 μg/mL Compound: 5-FU	Cytotoxicity against human HCT-116 cells Cytotoxicity against human HCT-116 cells	[PMID: 34655985]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 23665106]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 26703795]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay Antiproliferative activity against human HCT116 cells after 72 hrs by MTS assay	[PMID: 27575478]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells by MTS assay Cytotoxicity against human HCT116 cells by MTS assay	[PMID: 29843103]
HCT-116	IC₅₀	5.53 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human HCT116 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
HCT-116	IC₅₀	5.78 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay Cytotoxicity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 24378217]
HCT-116	IC₅₀	5.78 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells after 72 hrs by MTT assay	[PMID: 35609396]
HCT-116	IC₅₀	5.8 μM Compound: 5-Fu	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
HCT-116	IC₅₀	53.84 μM Compound: 2; 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 29202398]
HCT-116	IC₅₀	56.96 μM Compound: 5-Fuorouracil	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 27017265]
HCT-116	IC₅₀	6 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 25462277]
HCT-116	IC₅₀	6 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay	[PMID: 38107180]
HCT-116	IC₅₀	6 μM Compound: 5-Fu	Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay Cytotoxicity against human HCT116 cells after 72 hrs by SRB assay	[PMID: 22409771]
HCT-116	IC₅₀	6.1 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
HCT-116	IC₅₀	6.36 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human HCT116 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
HCT-116	IC₅₀	6.5 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells incubated for 72 hrs by MTT assay	[PMID: 36209705]
HCT-116	IC₅₀	6.5 μM Compound: 5-fluorouracil	Cytotoxicity against human HCT116 cells after 48 hrs by CellTiter-Glo assay Cytotoxicity against human HCT116 cells after 48 hrs by CellTiter-Glo assay	[PMID: 31999116]
HCT-116	IC₅₀	6.86 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
HCT-116	IC₅₀	6.86 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human HCT116 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
HCT-116	IC₅₀	63.9 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human HCT116 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
HCT-116	IC₅₀	68.71 μM Compound: 5-Fu	Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells measured after 48 hrs by MTT assay	[PMID: 27287368]
HCT-116	IC₅₀	6 μg/mL Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 22154835]
HCT-116	IC₅₀	7.38 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 34170142]
HCT-116	IC₅₀	7.77 μM Compound: 5-FU	Antitumor activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human HCT-116 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
HCT-116	IC₅₀	8.03 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells incubated for 72 hrs by MTS assay Cytotoxicity against human HCT-116 cells incubated for 72 hrs by MTS assay	[PMID: 38843656]
HCT-116	IC₅₀	8.2 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 to 72 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth measured after 48 to 72 hrs by MTT assay	[PMID: 37902628]
HCT-116	IC₅₀	8.32 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay Cytotoxicity against human HCT116 cells after 72 hrs by MTT assay	[PMID: 24211021]
HCT-116	IC₅₀	8.51 μM Compound: 5-FU	Anticancer activity against human HCT116 cells Anticancer activity against human HCT116 cells	[PMID: 21449610]
HCT-116	IC₅₀	8.51 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 22409967]
HCT-116	IC₅₀	8.62 μM Compound: 5-FU	Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay Cytotoxicity in human HCT116 cells incubated for 48 hrs by MTT assay	[PMID: 28923381]
HCT-116	IC₅₀	8.638 μM Compound: 5-FU	Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT116 cells after 48 hrs by MTT assay	[PMID: 29223717]
HCT-116	IC₅₀	8.75 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 39016216]
HCT-116	IC₅₀	84.9 μM Compound: 2; 5-FU	Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells after 48 hrs by MTT assay	[PMID: 27322756]
HCT-116	IC₅₀	9.63 μM Compound: 5-FU	Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38759254]
HCT-116	IC₅₀	9.88 μM Compound: 5-FU	Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
HCT-116	IC₅₀	9.9 μM Compound: 5-FU	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 28431341]
HCT-116	IC₅₀	9.93 μM Compound: 1; 5-FU	Growth inhibition of human HCT-116 cells incubated for 1.5 hrs by MTT assay Growth inhibition of human HCT-116 cells incubated for 1.5 hrs by MTT assay	[PMID: 38107178]
HCT-116	IC₅₀	91.73 μM Compound: 5-FU	Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HCT-116 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HCT-116	IC₅₀	> 20 μM Compound: 5-Fu	Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human HCT-116 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 38897138]
HCT-116	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 24 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 24 hrs by MTT assay	[PMID: 26922233]
HCT-116	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Anticancer activity against human HCT116 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26922233]
HCT-15	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-15	GI₅₀	0.11 μM Compound: 5-FU	Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HCT-15	GI₅₀	0.11 μM Compound: 5-FU	Anticancer activity against human HCT-15 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HCT-15 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HCT-15	GI₅₀	21 μM Compound: 5-Fu	Growth inhibition of human HCT15 cells after 48 hrs by SRB assay Growth inhibition of human HCT15 cells after 48 hrs by SRB assay	[PMID: 22512908]
HCT-15	GI₅₀	21.1 nM Compound: 5FU	Growth inhibition of human HCT15 cells after 48 hrs by SRB assay Growth inhibition of human HCT15 cells after 48 hrs by SRB assay	[PMID: 23094992]
HCT-15	IC₅₀	0.11 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT-15 cells assessed as cell growth inhibition Cytotoxicity against human HCT-15 cells assessed as cell growth inhibition	[PMID: 36470105]
HCT-15	IC₅₀	0.11 μg/mL Compound: 5-FU	Inhibitory concentration of compound for cytotoxicity against HCT15 human colon cells was determined Inhibitory concentration of compound for cytotoxicity against HCT15 human colon cells was determined	[PMID: 11814824]
HCT-15	IC₅₀	10.86 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human HCT-15 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
HCT-15	IC₅₀	11.87 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay	[PMID: 30318440]
HCT-15	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human HCT-15 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay Cytotoxicity against human HCT-15 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay	[PMID: 37243616]
HCT-15	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HCT-15	IC₅₀	18.24 μM Compound: 5-FU	Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human HCT15 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
HCT-15	IC₅₀	3.6 μM Compound: 5-fluorouracil	Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human HCT15 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HCT-15	IC₅₀	300 μM Compound: 5-FU	Growth inhibition in HCT15 cells assessed as inhibition of [3H]thymidine incorporation Growth inhibition in HCT15 cells assessed as inhibition of [3H]thymidine incorporation	[PMID: 17411027]
HCT-15	IC₅₀	33.68 μM Compound: 5-fluorouracil	Antiproliferative activity against human HCT-15 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human HCT-15 cells assessed as cell growth inhibition by MTT assay	[PMID: 31945642]
HCT-15	IC₅₀	4.5 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HCT15 cells after 48 hrs by sulforhodamine B assay	[PMID: 24910974]
HCT-15	IC₅₀	45.01 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay Cytotoxicity against human HCT15 cells after 24 hrs by MTT assay	[PMID: 23202484]
HCT-15	IC₅₀	45.01 μM Compound: 5-FU	Growth inhibition of human HCT15 cells after 24 hrs by MTT assay Growth inhibition of human HCT15 cells after 24 hrs by MTT assay	[PMID: 28011220]
HCT-15	IC₅₀	48 μM Compound: 5-FU	Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human HCT15 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
HCT-15	IC₅₀	5.7 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of HCT-15 tumor cell line from colon. Compound was tested for its inhibitory effect on the growth of HCT-15 tumor cell line from colon.	10.1016/0960-894X(96)00339-3
HCT-15	IC₅₀	6.61 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human HCT15 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
HCT-15	IC₅₀	6.61 μM Compound: 5-fluorouracil	Cytotoxicity against human HCT15 cells Cytotoxicity against human HCT15 cells	[PMID: 16996657]
HCT-15	IC₅₀	7.53 μM Compound: 5-FU	Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay Cytotoxicity against human HCT15 cells after 72 hrs by MTT assay	[PMID: 30677614]
HCT-15	IC₅₀	7.53 μM Compound: 5-Fu	Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay Cytotoxicity against human HCT15 cells after 48 hrs by MTT assay	[PMID: 29174813]
HCT-15	IC₅₀	8.23 μM Compound: 5-FU	Antiproliferative activity against human HCT-15 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT-15 cells incubated for 72 hrs by MTT assay	[PMID: 36209705]
HCT-15	IC₅₀	8.24 μM Compound: 5-FU	Anticancer activity against human HCT-15 cells incubated for 72 hrs by MTT assay Anticancer activity against human HCT-15 cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
HCT-15	IC₅₀	9.71 μM Compound: 5-FU	Anticancer activity against human HCT15 cells Anticancer activity against human HCT15 cells	[PMID: 21449610]
HCT-15	IC₅₀	9.71 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT15 cells Cytotoxicity against human HCT15 cells	[PMID: 22409967]
HCT-8	IC₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HCT8 after 24 hrs by MTT assay Cytotoxicity against human HCT8 after 24 hrs by MTT assay	[PMID: 19338315]
HCT-8	IC₅₀	0.54 μg/mL Compound: 5-FU, 5-fluorouracil	Cytotoxicity against human HCT8 cells by MTT assay Cytotoxicity against human HCT8 cells by MTT assay	[PMID: 18205316]
HCT-8	IC₅₀	0.91 μM Compound: 5-FU	Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25675144]
HCT-8	IC₅₀	11.18 μM Compound: 5-FU	Antiproliferative activity against human HCT-8 cells assessed as cell growth inhibition Antiproliferative activity against human HCT-8 cells assessed as cell growth inhibition	[PMID: 33930801]
HCT-8	IC₅₀	2.2 μM Compound: 5-FU	Cytotoxicity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-8	IC₅₀	28.9 μM Compound: 5-FU	Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay	[PMID: 30037494]
HCT-8	IC₅₀	28.9 μM Compound: 5-FU	Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay Antiproliferative activity against human HCT8 cells after 72 hrs by MTT assay	[PMID: 30429977]
HCT-8	IC₅₀	3.54 μM Compound: 5-FU	Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells assessed as growth inhibition rate after 96 hrs by MTT assay	[PMID: 25203783]
HCT-8	IC₅₀	32.31 μM Compound: 5-FU	Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HCT8 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
HCT-8	IC₅₀	36.638 μM Compound: 5-FU	Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against 5-FU resistant human HCT8 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25675144]
HCT-8	IC₅₀	4.2 μM Compound: 5-Fu	Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay	[PMID: 16499317]
HCT-8	IC₅₀	4.7 μM Compound: 5-FU	Antiproliferative activity against human HCT-8 cells assessed as cell growth inhibition in presence of piperlongumine Antiproliferative activity against human HCT-8 cells assessed as cell growth inhibition in presence of piperlongumine	[PMID: 33930801]
HCT-8	IC₅₀	47 μM Compound: 5-FU	Cytotoxicity against 5-FU resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against 5-FU resistant human HCT-8 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 33321421]
HCT-8	IC₅₀	5.38 μM Compound: 5-Fu	Cytotoxicity against human HCT8 cells by MTT method Cytotoxicity against human HCT8 cells by MTT method	[PMID: 23164710]
HCT-8	IC₅₀	6.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay Cytotoxicity against human HCT8 cells after 72 hrs by MTT assay	[PMID: 26227777]
HCT-8	IC₅₀	6.92 μM Compound: 5-Fu	Antiproliferative activity against human HCT8 cells by MTT assay Antiproliferative activity against human HCT8 cells by MTT assay	[PMID: 24095094]
HCT-8	IC₅₀	> 20 μM Compound: 5-FU	Antiproliferative activity against human HCT-8 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HCT-8 cells incubated for 72 hrs by MTT assay	[PMID: 36209705]
HEK-293T	IC₅₀	17.57 μM Compound: 5-FU	Antiproliferative activity against human HEK293T cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human HEK293T cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38677112]
HEK-293T	IC₅₀	4.07 μM Compound: 5-FU	Antiproliferative activity against HEK293T cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay Antiproliferative activity against HEK293T cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay	[PMID: 38626522]
HEK-293T	IC₅₀	56.21 μM Compound: 5-FU	Antiproliferative activity against HEK293T Antiproliferative activity against HEK293T	[PMID: 38716896]
HEK-293T	IC₅₀	> 100 μM Compound: 5-FU	Growth inhibition of HEK293T cells after 24 hrs by MTT assay Growth inhibition of HEK293T cells after 24 hrs by MTT assay	[PMID: 28011220]
HEK293	IC₅₀	19.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HEK293 cells by MTT assay Antiproliferative activity against human HEK293 cells by MTT assay	[PMID: 29798826]
HEK293	IC₅₀	2.15 μM Compound: 5-Florouracil	Cytotoxicity against Homo sapiens (human) HEK293 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay Cytotoxicity against Homo sapiens (human) HEK293 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay	10.1007/s00044-012-0260-2
HEK293	IC₅₀	40 μM Compound: 5 Fluorouracil	Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human HEK293 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
HEK293	IC₅₀	41.01 μM Compound: 5-Fu	Antiproliferative activity against human HEK293 cells after 72 hrs by MTT assay Antiproliferative activity against human HEK293 cells after 72 hrs by MTT assay	[PMID: 35609396]
HEK293	IC₅₀	42.9 μM Compound: 5-FU	Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay Cytotoxicity against human HEK293 cells after 2 days by alamar blue assay	[PMID: 22093761]
HEK293	IC₅₀	48.7 μM Compound: 5-FU	Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay Antiproliferative activity against HEK293 cells after 24 hrs by MTT assay	[PMID: 25198997]
HEK293	IC₅₀	5.11 μM Compound: 1; 5-FU	Cytotoxicity against HEK293 cells assessed as inhibition of cell growth incubated 1.5 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as inhibition of cell growth incubated 1.5 hrs by MTT assay	[PMID: 38107178]
HEK293	IC₅₀	79.32 μM Compound: 5-FU	Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 32203786]
HEL	IC₅₀	15.98 μM Compound: 5-fluorouracil	Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HEL cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
HEL	IC₅₀	32.27 μM Compound: 2; 5-FU	Antiproliferative activity against human HEL cells after 48 hrs by MTT assay Antiproliferative activity against human HEL cells after 48 hrs by MTT assay	[PMID: 27322756]
HEp-2	IC₅₀	0.3 μM Compound: 5-fluorouracil	Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human Hep2 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
HEp-2	IC₅₀	128.7 μM Compound: 5-FU	Antiproliferative activity against human Hep2 cells after 72 hrs by MTT method Antiproliferative activity against human Hep2 cells after 72 hrs by MTT method	[PMID: 17524655]
HEp-2	IC₅₀	128.7 μM Compound: 5-Fu	Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay Cytotoxicity against human Hep2 cells after 72 hrs by MTT assay	[PMID: 23792763]
HEp-2	IC₅₀	2 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) Hep2 cells by SRB assay Cytotoxicity against Homo sapiens (human) Hep2 cells by SRB assay	10.1007/s00044-010-9500-5
HEp-2	IC₅₀	24.58 μM Compound: 5-Fu	Cytotoxicity against human Hep2 cells by MTT assay Cytotoxicity against human Hep2 cells by MTT assay	[PMID: 22801644]
HEp-2	IC₅₀	4.5 μM Compound: 5-FU	Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human Hep2 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
HEp-2	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human Hep2 cells after 72 hrs by MTT assay Antiproliferative activity against human Hep2 cells after 72 hrs by MTT assay	[PMID: 21524829]
HGC-27	IC₅₀	0.5 μM Compound: 5-Fu	Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 37360398]
HGC-27	IC₅₀	11.02 μM Compound: 5-FU	Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay	[PMID: 28759876]
HGC-27	IC₅₀	14.72 μM Compound: 5-FU	Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay Cytotoxicity against human HGC27 cells after 48 hrs by MTT assay	[PMID: 28431881]
HGC-27	IC₅₀	18 μM Compound: 5-FU	Cytotoxicity against human HGC27 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human HGC27 cells assessed as reduction in cell viability by MTT assay	[PMID: 31029946]
HGC-27	IC₅₀	27.5 μM Compound: 5-Fu	Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
HGC-27	IC₅₀	4.28 μM Compound: 5-FU	Anticancer activity against human HGC-27 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human HGC-27 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
HGC-27	IC₅₀	45.2 μM Compound: 5-FU	Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 35286954]
HGC-27	IC₅₀	5.75 μM Compound: 5-Fu	Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
HGC-27	IC₅₀	76.62 μM Compound: 5-FU	Cytotoxicity in human HGC-27 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HGC-27 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HGC-27	IC₅₀	8.22 μM Compound: 5-FU	Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay	[PMID: 30108876]
HGC-27	IC₅₀	8.22 μM Compound: 5-Fu	Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay Antiproliferative activity against human HGC27 cells after 72 hrs by MTT assay	[PMID: 28456031]
HGC-27	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HGC-27 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
HL-60	CC₅₀	0.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human HL60 cells after 5 days by MTT assay Cytotoxicity against human HL60 cells after 5 days by MTT assay	[PMID: 20227144]
HL-60	GI₅₀	3.8 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining Antiproliferative activity against human HL60 cells after 3 days by trypan blue staining	[PMID: 18491866]
HL-60	IC₅₀	0.06 μM Compound: 5-FU	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 22959518]
HL-60	IC₅₀	0.16 μM Compound: fluorouracil	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 17291040]
HL-60	IC₅₀	1.33 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human promyelocytic leukemia (HL-60) cells In vitro inhibitory activity against growth of Human promyelocytic leukemia (HL-60) cells	[PMID: 1995901]
HL-60	IC₅₀	1.3 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human promyelocytic leukemia (HL-60) cell line. In vitro inhibitory activity against Human promyelocytic leukemia (HL-60) cell line.	[PMID: 1995905]
HL-60	IC₅₀	1.5 μM Compound: 5-flurouracil	In vitro inhibitory concentration against proliferation of HL60 cells In vitro inhibitory concentration against proliferation of HL60 cells	[PMID: 12877593]
HL-60	IC₅₀	1.62 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay Antiproliferative activity against human HL60 cells after 48 hrs by MTS assay	[PMID: 28152430]
HL-60	IC₅₀	10.05 μM Compound: 5-Fu	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 23558238]
HL-60	IC₅₀	10.05 μM Compound: 5-Fu	Growth inhibition against human HL60 cells after 48 hrs by MTT assay Growth inhibition against human HL60 cells after 48 hrs by MTT assay	[PMID: 23999046]
HL-60	IC₅₀	10.45 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 25529742]
HL-60	IC₅₀	2.37 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 29407983]
HL-60	IC₅₀	2.37 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 29524728]
HL-60	IC₅₀	2.45 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
HL-60	IC₅₀	2.7 pM Compound: 5-FU	Cytotoxicity against human HL60 cells after 72 hrs by MTT assay Cytotoxicity against human HL60 cells after 72 hrs by MTT assay	[PMID: 21640594]
HL-60	IC₅₀	2.8 μM Compound: 5-Fu	Cytotoxic activity against human HL60 cells Cytotoxic activity against human HL60 cells	[PMID: 28697923]
HL-60	IC₅₀	2.8 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method Antiproliferative activity against human HL60 cells after 72 hrs by tryphan blue staining based hematocytometric method	[PMID: 29131616]
HL-60	IC₅₀	21.38 μM Compound: 5-FU	Cytotoxicity against human HL60 cells by MTT assay Cytotoxicity against human HL60 cells by MTT assay	[PMID: 18644718]
HL-60	IC₅₀	22.3 μM Compound: 5-FU	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 23867385]
HL-60	IC₅₀	22.54 μM Compound: FUra	Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 25644674]
HL-60	IC₅₀	25.4 μg/mL Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HL60 cells by MTT assay Cytotoxicity against Homo sapiens (human) HL60 cells by MTT assay	10.1007/s00044-009-9193-9
HL-60	IC₅₀	266 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HL60 cells after 96 hr by MTT assay Cytotoxicity against Homo sapiens (human) HL60 cells after 96 hr by MTT assay	10.1007/s00044-011-9778-y
HL-60	IC₅₀	266 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HL60 cells after 48 hrs by sulforhodamine B assay	[PMID: 22424614]
HL-60	IC₅₀	27.01 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay	[PMID: 25164762]
HL-60	IC₅₀	27.43 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HL-60	IC₅₀	3.46 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells after 72 hrs by MTT assay	[PMID: 29635169]
HL-60	IC₅₀	3.69 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human HL60 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
HL-60	IC₅₀	38.13 μM Compound: 5-FU	Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition in presence of piperlongumine Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition in presence of piperlongumine	[PMID: 33930801]
HL-60	IC₅₀	42.8 μM Compound: 5-FU	Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay Cytotoxicity against human HL60 cells assessed as reduction in cell viability measured after 48 hrs by CCK8 assay	[PMID: 31253531]
HL-60	IC₅₀	5.4 μM Compound: 5-FU	Anticancer activity against Homo sapiens (human) HL60 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay Anticancer activity against Homo sapiens (human) HL60 cells assessed as inhibition of cell proliferation after 72 hr by MTT assay	10.1007/s00044-012-0240-6
HL-60	IC₅₀	54.54 μM Compound: 5-Fu	Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay	[PMID: 29958763]
HL-60	IC₅₀	65.3 μM Compound: 5-FU	In vitro inhibitory concentration required against human leukemic HL-60 cell line was determined after 48 hrs of drug exposure using MTT method In vitro inhibitory concentration required against human leukemic HL-60 cell line was determined after 48 hrs of drug exposure using MTT method	[PMID: 15380199]
HL-60	IC₅₀	65.3 μM Compound: 5-FU	Cytotoxicity against human HL60 cells after 48 hrs by MTT assay Cytotoxicity against human HL60 cells after 48 hrs by MTT assay	[PMID: 19324555]
HL-60	IC₅₀	67.2 μM Compound: 5-FU	Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay	[PMID: 29305189]
HL-60	IC₅₀	68.3 μM Compound: 5-Fu	Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay Cytotoxicity against human HL60 cells after 48 hrs by CCK-8 assay	[PMID: 22244588]
HL-60	IC₅₀	81.13 μM Compound: 5-FU	Cytotoxicity in human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HL-60 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HL-60	IC₅₀	84.68 μM Compound: 5-FU	Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition Antiproliferative activity against human HL-60 cells assessed as cell growth inhibition	[PMID: 33930801]
HL-60	IC₅₀	85.1 μM Compound: 5-fluorouracil	Cytotoxicity against human HL60 (TB) cells Cytotoxicity against human HL60 (TB) cells	[PMID: 16996657]
HL-60	IC₅₀	9.1 μM Compound: 5-fluorouracil	Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21381696]
HL-60	IC₅₀	9.5 μM Compound: 5-fluorouracil	Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human HL60 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
HL-60	IC₅₀	> 100 μM Compound: 5-FU	Anticancer activity against human HL60 cells Anticancer activity against human HL60 cells	[PMID: 21449610]
HL-60	IC₅₀	> 30 μM Compound: 5-FU	Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HL60 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 29133061]
HL-60	IC₅₀	1.0 x 10^-6 M Compound: 5-Fu	Inhibitory concentration against Human leukemia cancer cell (HL-60)lines was determined. Inhibitory concentration against Human leukemia cancer cell (HL-60)lines was determined.	[PMID: 11229742]
HL-60(TB)	GI₅₀	100 nM Compound: 5FU	Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay	[PMID: 23094992]
HL-60(TB)	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay Growth inhibition of human HL-60(TB) cells after 48 hrs by SRB assay	[PMID: 22512908]
HL-60(TB)	GI₅₀	2.3 μM Compound: 5-FU	Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HL-60(TB) cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HL-60(TB)	GI₅₀	2.3 μM Compound: 5-FU	Anticancer activity against human HL-60(TB) cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HL-60(TB) cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HL-60(TB)	IC₅₀	2.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human HL-60(TB) cells assessed as cell growth inhibition Cytotoxicity against human HL-60(TB) cells assessed as cell growth inhibition	[PMID: 36470105]
HL-60(TB)	IC₅₀	85.1 μM Compound: 5-Fluorouracil	Antileukemic activity against human HL-60(TB) cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human HL-60(TB) cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
HL-60(TB)	IC₅₀	> 2512 μM Compound: 5-Fluorouracil	Cytotoxicity against human HL-60(TB) cells Cytotoxicity against human HL-60(TB) cells	[PMID: 22409967]
HOP-62	GI₅₀	0.39 μM Compound: 5-FU	Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HOP-62	GI₅₀	0.39 μM Compound: 5-FU	Anticancer activity against human HOP-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HOP-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HOP-62	GI₅₀	4.1 μM Compound: 5FU	Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP62 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
HOP-62	IC₅₀	0.39 μM Compound: 5-Fluorouracil	Cytotoxicity against human HOP-62 cells assessed as cell growth inhibition Cytotoxicity against human HOP-62 cells assessed as cell growth inhibition	[PMID: 36470105]
HOP-92	GI₅₀	77.9 μM Compound: 5-FU	Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HOP92 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HOP-92	GI₅₀	77.9 μM Compound: 5-FU	Anticancer activity against human HOP-92 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HOP-92 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HOP-92	IC₅₀	77.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human HOP-92 cells assessed as cell growth inhibition Cytotoxicity against human HOP-92 cells assessed as cell growth inhibition	[PMID: 36470105]
HOS	IC₅₀	0.79 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human osteogenic sarcoma (HOS) cells In vitro inhibitory activity against growth of Human osteogenic sarcoma (HOS) cells	[PMID: 1995901]
HSC-2	CC₅₀	13 μM Compound: 5-FU	Cytotoxicity against human HSC-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC-2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32795767]
HSC-2	CC₅₀	47 μM Compound: 5-FU	Cytotoxicity against human HSC2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31532650]
HSC-2	CC₅₀	> 1000 μM Compound: 5-FU	Cytotoxicity against human HSC-2 cells incubated for 48 hrs by MTT assay Cytotoxicity against human HSC-2 cells incubated for 48 hrs by MTT assay	[PMID: 33744685]
HSC-3	CC₅₀	13 μM Compound: 5-FU	Cytotoxicity against human HSC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32795767]
HSC-4	CC₅₀	25 μM Compound: 5-FU	Cytotoxicity against human HSC4 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HSC4 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31532650]
HT-1080	EC₅₀	0.29 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human HT1080 cells by MTT assay Antiproliferative activity against human HT1080 cells by MTT assay	[PMID: 12444707]
HT-1080	EC₅₀	1.38 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 12027739]
HT-1080	ED₅₀	0.48 μg/mL Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells after 4 days by MTT assay Antiproliferative activity against human HT1080 cells after 4 days by MTT assay	[PMID: 11374950]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Cytotoxicity against human HT1080 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide assay Cytotoxicity against human HT1080 cells by 3-(4,5-dimethylthiazol-2-yl)-2,5-dimethyltetrazolium bromide assay	[PMID: 11141109]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells by MTT assay Antiproliferative activity against human HT1080 cells by MTT assay	[PMID: 11277741]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells by MTT assay Antiproliferative activity against human HT1080 cells by MTT assay	[PMID: 11325233]
HT-1080	ED₅₀	8 μM Compound: 5-fluorouracil	Cytotoxicity against human HT1080 cells by MTT assay Cytotoxicity against human HT1080 cells by MTT assay	[PMID: 11430002]
HT-1080	IC₅₀	1.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HT1080 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 11575942]
HT-1080	IC₅₀	15.2 μM Compound: 5-FU	Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay	[PMID: 23067549]
HT-1080	IC₅₀	3.06 μM Compound: 5-Fu	Cytotoxicity against human HT1080 cells by MTT assay Cytotoxicity against human HT1080 cells by MTT assay	[PMID: 22801644]
HT-1080	IC₅₀	35.62 μM Compound: 5-Fu	Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay Cytotoxicity against human HT1080 cells after 48 hrs by MTT assay	[PMID: 23558238]
HT-1080	IC₅₀	35.62 μM Compound: 5-Fu	Growth inhibition against human HT1080 cells after 48 hrs by MTT assay Growth inhibition against human HT1080 cells after 48 hrs by MTT assay	[PMID: 23999046]
HT-1080	IC₅₀	3700 nM Compound: 5-fluorouracil	Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay Antiproliferative activity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 14640513]
HT-1080	IC₅₀	5.2 μM Compound: 5-fluorouracil	Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 19919052]
HT-1080	IC₅₀	6 μM Compound: 5-FU	Cytotoxicity against human HT-1080 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human HT-1080 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 37098306]
HT-1080	IC₅₀	70.8 μM Compound: 5-Fu	Cytotoxicity against human HT1080 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human HT1080 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 23647462]
HT-1080	IC₅₀	8.58 μM Compound: 5-Fluoro uracil	Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 19689125]
HT-1080	IC₅₀	9.45 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay Cytotoxicity against human HT1080 cells after 72 hrs by MTT assay	[PMID: 18440233]
HT-1376	IC₅₀	0.58 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human bladder carcinoma (HT1376) cells In vitro inhibitory activity against growth of Human bladder carcinoma (HT1376) cells	[PMID: 1995901]
HT-22	CC₅₀	8.1 μM Compound: 5-Fu	Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against mouse HT22 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32832031]
HT-29	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HT-29	ED₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 16309328]
HT-29	ED₅₀	7.4 x 10^-2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HT-29 cells by MTT assay Cytotoxicity against human HT-29 cells by MTT assay	[PMID: 11908984]
HT-29	ED₅₀	7.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT-29 cells by Alamar blue assay Cytotoxicity against human HT-29 cells by Alamar blue assay	[PMID: 24128077]
HT-29	GI₅₀	0.17 μM Compound: 5-FU	Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
HT-29	GI₅₀	0.17 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
HT-29	GI₅₀	0.4 μg/mL Compound: 5FU	Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
HT-29	GI₅₀	12.6 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells incubated for 48 hrs by MTT assay	[PMID: 32832031]
HT-29	GI₅₀	14.9 μM Compound: 5FU	Cytotoxicity against human HT-29 cells Cytotoxicity against human HT-29 cells	[PMID: 20356752]
HT-29	GI₅₀	8.9 μM Compound: 5FU	Cytotoxicity against human HT29 cells after 48 hrs Cytotoxicity against human HT29 cells after 48 hrs	[PMID: 18798609]
HT-29	IC₅₀	0.15 μM Compound: 5-fluorouracil	Antitumor activity against colon carcinoma cell line (HT-29) Antitumor activity against colon carcinoma cell line (HT-29)	[PMID: 2547068]
HT-29	IC₅₀	0.17 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT-29 cells assessed as cell growth inhibition Cytotoxicity against human HT-29 cells assessed as cell growth inhibition	[PMID: 36470105]
HT-29	IC₅₀	0.1 μg/mL Compound: 5-fluorouracil	Antitumor activity against human HT-29 cells Antitumor activity against human HT-29 cells	[PMID: 10579858]
HT-29	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human HT29 cells by MTT microassay Cytotoxicity against human HT29 cells by MTT microassay	[PMID: 17320246]
HT-29	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human HT29 cells by MTT assay Cytotoxicity against human HT29 cells by MTT assay	[PMID: 18606546]
HT-29	IC₅₀	1.08 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay Cytotoxicity against human HT-29 cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
HT-29	IC₅₀	10.2 μM Compound: 5-FU	Anticancer activity against human HT-29 cells Anticancer activity against human HT-29 cells	[PMID: 21449610]
HT-29	IC₅₀	10.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT-29 cells Cytotoxicity against human HT-29 cells	[PMID: 22409967]
HT-29	IC₅₀	10.26 μg/mL Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HT-29 cells by MTT assay Cytotoxicity against Homo sapiens (human) HT-29 cells by MTT assay	10.1007/s00044-009-9193-9
HT-29	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay Cytotoxicity against human HT-29 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay	[PMID: 37243616]
HT-29	IC₅₀	12.2 μM Compound: 5-FU	Antitumor activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human HT-29 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
HT-29	IC₅₀	12.67 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay	[PMID: 32992255]
HT-29	IC₅₀	13.37 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
HT-29	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
HT-29	IC₅₀	14.9 μM Compound: 1; 5-FU	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 33819035]
HT-29	IC₅₀	146.2 μM Compound: 5-FU	Cytotoxicity in human HT-29 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human HT-29 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
HT-29	IC₅₀	15.83 μM Compound: 5-fluorouracil	Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human HT-29 cells assessed as growth inhibition after 48 hrs by WST-1 assay	[PMID: 26413725]
HT-29	IC₅₀	15.96 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
HT-29	IC₅₀	16.07 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
HT-29	IC₅₀	17.2 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 2 days by MTT assay Cytotoxicity against human HT-29 cells after 2 days by MTT assay	[PMID: 24767839]
HT-29	IC₅₀	17.48 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
HT-29	IC₅₀	18.77 nM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36269639]
HT-29	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
HT-29	IC₅₀	2.58 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells after 3 days by SRB assay Cytotoxicity against human HT-29 cells after 3 days by SRB assay	[PMID: 24704691]
HT-29	IC₅₀	2.8 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 27092413]
HT-29	IC₅₀	22.12 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells incubated for 72 hrs by MTS assay Cytotoxicity against human HT-29 cells incubated for 72 hrs by MTS assay	[PMID: 38843656]
HT-29	IC₅₀	22.23 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay	[PMID: 29958763]
HT-29	IC₅₀	23.9 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
HT-29	IC₅₀	24.5 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 23665106]
HT-29	IC₅₀	24.5 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay Antiproliferative activity against human HT-29 cells after 72 hrs by MTS assay	[PMID: 26703795]
HT-29	IC₅₀	24.87 μM Compound: 5-Fu	Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by Alamar Blue assay	[PMID: 24583355]
HT-29	IC₅₀	25 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26922233]
HT-29	IC₅₀	25.08 μM Compound: FUra	Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
HT-29	IC₅₀	25.9 μM Compound: 5-fluorouracil	Antiproliferative activity against human HT-29 cells cultured as 3D spheroids assessed as inhibition of spheroid formation measured after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells cultured as 3D spheroids assessed as inhibition of spheroid formation measured after 48 hrs by MTT assay	[PMID: 33872002]
HT-29	IC₅₀	3.24 μM Compound: 5-Fluorouracil	Cytotoxicity against Homo sapiens (human) HT-29 cells assessed as inhibition of cell growth after 48 hr by MTT assay Cytotoxicity against Homo sapiens (human) HT-29 cells assessed as inhibition of cell growth after 48 hr by MTT assay	10.1007/s00044-012-0209-5
HT-29	IC₅₀	4.6 μM Compound: 5-Fluorouracil	Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Antitumor activity against human HT-29 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
HT-29	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 72 hrs by MTT assay	[PMID: 28494251]
HT-29	IC₅₀	5.2 μM Compound: 1; 5-FU	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay Cytotoxicity against human HT-29 cells assessed as reduction in cell viability measured after 48 hrs in presence of 5 mM GSH by SRB assay	[PMID: 33819035]
HT-29	IC₅₀	5.3 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human HT-29 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
HT-29	IC₅₀	5.31 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay	[PMID: 36923920]
HT-29	IC₅₀	540 μM Compound: 5-FU	Cytotoxicity against HT29 cells after 48 hrs by MTT assay Cytotoxicity against HT29 cells after 48 hrs by MTT assay	[PMID: 17604394]
HT-29	IC₅₀	6.3 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 26922233]
HT-29	IC₅₀	6.35 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HT-29 cells after 48 hrs by sulforhodamine B assay	[PMID: 23644215]
HT-29	IC₅₀	6.5 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30368201]
HT-29	IC₅₀	690 nM Compound: Fluorouracil	Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 96 hrs by MTT assay	[PMID: 2778449]
HT-29	IC₅₀	7.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against human HT-29 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
HT-29	IC₅₀	7.3 μM Compound: 5-FU	Antiproliferative activity against HT29 cells Antiproliferative activity against HT29 cells	[PMID: 17110105]
HT-29	IC₅₀	7.3 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method Antiproliferative activity against human HT-29 cells assessed as growth inhibition after 144 hrs by crystal violet staining method	[PMID: 22450132]
HT-29	IC₅₀	7.3 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method Antiproliferative activity against human HT-29 cells after 72 hrs by crystal violet staining method	[PMID: 22765897]
HT-29	IC₅₀	7.3 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining Cytotoxicity against human HT-29 cells after 72 hrs by crystal violet staining	[PMID: 22959205]
HT-29	IC₅₀	8.3 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HT-29 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 29133061]
HT-29	IC₅₀	80.6 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay Anticancer activity against human HT-29 cells assessed as cell growth inhibition measured after 24 hrs by MTT assay	[PMID: 36481599]
HT-29	IC₅₀	9.19 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells incubated for 72 hrs by MTT assay	[PMID: 36209705]
HT-29	IC₅₀	9.72 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) HT-29 cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) HT-29 cells after 72 hr by MTT assay	10.1007/s00044-011-9549-9
HT-29	IC₅₀	9.99 μM Compound: 5-FU	Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
HT-29	IC₅₀	> 10 μM Compound: 5-FU	Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
HT-29	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human HT-29 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
HT-29	IC₅₀	> 100 μM Compound: 5-Fu	Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
HT-29	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 24 hrs by MTT assay Anticancer activity against human HT-29 cells assessed as inhibition of cell growth after 24 hrs by MTT assay	[PMID: 26922233]
HUVEC	GI₅₀	3.6 nM Compound: 5FU	Growth inhibition of human HUVEC cells after 48 hrs by SRB assay Growth inhibition of human HUVEC cells after 48 hrs by SRB assay	[PMID: 23094992]
HUVEC	GI₅₀	9.72 μM Compound: 5-Fu	Growth inhibition of HUVEC cells after 48 hrs by SRB assay Growth inhibition of HUVEC cells after 48 hrs by SRB assay	[PMID: 22512908]
HUVEC	IC₅₀	0.43 μM Compound: 1; 5-FU	Cytotoxicity against human HUVEC cells assessed as inhibition of cell growth incubated 1.5 hrs by MTT assay Cytotoxicity against human HUVEC cells assessed as inhibition of cell growth incubated 1.5 hrs by MTT assay	[PMID: 38107178]
HUVEC	IC₅₀	11.65 μM Compound: 5-FU	Cytotoxicity against HUVEC Cytotoxicity against HUVEC	[PMID: 30746067]
HUVEC	IC₅₀	24.12 μM Compound: 5-Fu	Cytotoxicity against HUVEC after 48 hrs by MTT assay Cytotoxicity against HUVEC after 48 hrs by MTT assay	[PMID: 24953029]
HUVEC	IC₅₀	56 μM Compound: 5-FU	Cytotoxicity against human HUVEC after 48 hrs by MTT assay Cytotoxicity against human HUVEC after 48 hrs by MTT assay	[PMID: 24378217]
HUVEC	IC₅₀	56 μM Compound: 5-FU	Cytotoxicity against human HUVEC cells after 48 hrs by MTT assay Cytotoxicity against human HUVEC cells after 48 hrs by MTT assay	[PMID: 25151580]
HUVEC	IC₅₀	56 μM Compound: 5-FU	Cytotoxicity in HUVEC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in HUVEC cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 28754470]
HUVEC	IC₅₀	56.37 μM Compound: 5-Fu	Cytotoxicity against human HUVEC cells after 2 days by MTT assay Cytotoxicity against human HUVEC cells after 2 days by MTT assay	[PMID: 25841196]
HUVEC	IC₅₀	79.6 μM Compound: 5-Fluorouracil	Cytotoxicity against HUVEC assessed as cell growth inhibition by MTT assay Cytotoxicity against HUVEC assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
HUVEC	IC₅₀	96 μM Compound: 5-FLU	Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 34606997]
HUVEC	IC₅₀	> 200 μM Compound: 5-FLU	Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against HUVEC assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 34606997]
HaCaT	IC₅₀	0.3 μM Compound: 5-Fluorouracil	Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay Cytostatic activity against human HaCaT cells after 72 hrs by MTT assay	[PMID: 22405290]
HaCaT	IC₅₀	0.4 μM Compound: 5-FU	Growth inhibition of human HaCaT cells after 72 hrs by MTT assay Growth inhibition of human HaCaT cells after 72 hrs by MTT assay	[PMID: 18640746]
HaCaT	IC₅₀	15.26 μM Compound: 5-Fluorouracil	Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxic activity against human HaCaT cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
HaCaT	IC₅₀	16.15 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay Antiproliferative activity against human HaCaT cells after 48 hrs by MTT assay	[PMID: 27092413]
HeLa	EC₅₀	0.23 μM Compound: 5-fluorouracil	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 12027739]
HeLa	EC₅₀	31.02 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 21889345]
HeLa	EC₅₀	79.79 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 20409617]
HeLa	GI₅₀	10 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19572613]
HeLa	GI₅₀	15 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay	[PMID: 28728108]
HeLa	GI₅₀	15 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human HeLa cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
HeLa	GI₅₀	15 μM Compound: 5-FU	Growth inhibition of human HeLa cells measured after 48 hrs by SRB colorimetric assay Growth inhibition of human HeLa cells measured after 48 hrs by SRB colorimetric assay	[PMID: 37137247]
HeLa	GI₅₀	15 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
HeLa	GI₅₀	16 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells assessed as reduction in cell growth Antiproliferative activity against human HeLa cells assessed as reduction in cell growth	[PMID: 34847410]
HeLa	GI₅₀	19 μM Compound: 5-FU	Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay Growth inhibition of human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
HeLa	GI₅₀	30.21 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay Antiproliferative activity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24934992]
HeLa	IC₅₀	0.04 mg/mL Compound: 5-Fu	Cytotoxicity against human HeLa cells after 3 days MTT assay Cytotoxicity against human HeLa cells after 3 days MTT assay	[PMID: 22796042]
HeLa	IC₅₀	0.113 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as cell growth inhibition Cytotoxicity against human HeLa cells assessed as cell growth inhibition	[PMID: 35964428]
HeLa	IC₅₀	0.18 μM Compound: 5-FU	Cytostatic activity against human HeLa cells in presence of 20 uM 2'-deoxyuridine Cytostatic activity against human HeLa cells in presence of 20 uM 2'-deoxyuridine	[PMID: 21330014]
HeLa	IC₅₀	0.199 μM Compound: 5-FU	Anticancer activity against human HeLa cells incubated for 72 hrs by MTT assay Anticancer activity against human HeLa cells incubated for 72 hrs by MTT assay	[PMID: 36921275]
HeLa	IC₅₀	0.23 μM Compound: 1, 5-FU	Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting Cytostatic activity against thymidine-kinase deficient human HeLa cells after 72 hrs by cell counting	[PMID: 21892829]
HeLa	IC₅₀	0.28 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 22959518]
HeLa	IC₅₀	0.44 μM Compound: 5-Fluoro uracil	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 19689125]
HeLa	IC₅₀	0.44 μg/mL Compound: 5FU	Cytotoxicity against human HeLa S3 cells Cytotoxicity against human HeLa S3 cells	[PMID: 10425135]
HeLa	IC₅₀	0.45 μM Compound: 5-FU	Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis Cytostatic activity against human HeLa cells after 3 days by coulter counting analysis	[PMID: 21330014]
HeLa	IC₅₀	0.54 μM Compound: 1, 5-FU	Cytostatic activity against human HeLa cells after 72 hrs by cell counting Cytostatic activity against human HeLa cells after 72 hrs by cell counting	[PMID: 21892829]
HeLa	IC₅₀	0.54 μM Compound: 5-Fluorouracil	Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis Cytostatic activity against human HeLa cells after 3 days by coulter counter analysis	[PMID: 22405290]
HeLa	IC₅₀	0.54 μM Compound: 5-Fluorouracil	Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method Cytostatic activity against human HeLa cells assessed as inhibition of proliferation after 72 hrs by Coulter cell counting method	[PMID: 24906510]
HeLa	IC₅₀	0.54 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation	[PMID: 26001344]
HeLa	IC₅₀	0.54 μM Compound: 5-Fluorouracil	Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method Anti-proliferative activity against human HeLa cells measured after 4 days by coulter counter method	[PMID: 27750154]
HeLa	IC₅₀	0.54 μM Compound: 5FU	Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay Cytotoxicity against human HeLa cells assessed as reduction in cell number after 72 hrs by cell counting assay	[PMID: 24631358]
HeLa	IC₅₀	0.54 μM Compound: F-Uracil	Cytostatic activity against human HeLa cells Cytostatic activity against human HeLa cells	[PMID: 21917363]
HeLa	IC₅₀	0.57 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis Cytotoxicity against human HeLa cells after 4 days by coulter counter analysis	[PMID: 21232828]
HeLa	IC₅₀	0.77 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 18440233]
HeLa	IC₅₀	0.887 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24021891]
HeLa	IC₅₀	0.8 μg/mL Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 23994872]
HeLa	IC₅₀	1 μM Compound: 5-FU	Cytostatic activity against human HeLa cells in presence of 500 uM uracil Cytostatic activity against human HeLa cells in presence of 500 uM uracil	[PMID: 21330014]
HeLa	IC₅₀	1.01 μg/mL Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by SRB assay Cytotoxicity against human HeLa cells after 48 hrs by SRB assay	[PMID: 19932530]
HeLa	IC₅₀	1.1 μM Compound: 5-FU	Cytostatic activity against human HeLa cells in presence of 500 uM uridine Cytostatic activity against human HeLa cells in presence of 500 uM uridine	[PMID: 21330014]
HeLa	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24060486]
HeLa	IC₅₀	1.28 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 23352638]
HeLa	IC₅₀	1.3 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 24835633]
HeLa	IC₅₀	1.4 μM Compound: 5-F	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 28254697]
HeLa	IC₅₀	1.4 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 22011319]
HeLa	IC₅₀	1.5 μM Compound: 5-FU	Cytostatic activity against human HeLa cells in presence of 20 uM thymidine Cytostatic activity against human HeLa cells in presence of 20 uM thymidine	[PMID: 21330014]
HeLa	IC₅₀	1.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
HeLa	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
HeLa	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
HeLa	IC₅₀	1.8 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
HeLa	IC₅₀	1.8 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
HeLa	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells by MTT assay Antiproliferative activity against human HeLa cells by MTT assay	[PMID: 29798826]
HeLa	IC₅₀	1.86 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28431881]
HeLa	IC₅₀	1.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
HeLa	IC₅₀	1.94 μM Compound: 5-FU	Antitumor activity against human HeLa cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human HeLa cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
HeLa	IC₅₀	10 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19795843]
HeLa	IC₅₀	10 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 31200236]
HeLa	IC₅₀	10 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19618920]
HeLa	IC₅₀	10 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 19919065]
HeLa	IC₅₀	10 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 20405881]
HeLa	IC₅₀	10.31 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21524829]
HeLa	IC₅₀	10.36 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 22801644]
HeLa	IC₅₀	10.72 μM Compound: 5-FU	Cytotoxicity against human HeLa assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
HeLa	IC₅₀	10.72 μg/mL Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
HeLa	IC₅₀	10.75 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 30318440]
HeLa	IC₅₀	108 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells Cytotoxicity against human HeLa cells	[PMID: 22283451]
HeLa	IC₅₀	110.16 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 21962523]
HeLa	IC₅₀	12 μM Compound: 5-Fu	Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human HeLa cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
HeLa	IC₅₀	12.3 μM Compound: 5-FU	Anticancer activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Anticancer activity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33940466]
HeLa	IC₅₀	12.7 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
HeLa	IC₅₀	120.4 μM Compound: 5-FU	Cytotoxicity in human HeLa cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human HeLa cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
HeLa	IC₅₀	13.45 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25506718]
HeLa	IC₅₀	13.9 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST8 assay	[PMID: 28488862]
HeLa	IC₅₀	13.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 72 hrs by WST-8 assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability measured after 72 hrs by WST-8 assay	[PMID: 33383442]
HeLa	IC₅₀	13.9 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells incubated for 72 hrs by WST-8 assay Cytotoxicity against human HeLa cells incubated for 72 hrs by WST-8 assay	[PMID: 32125158]
HeLa	IC₅₀	132.99 μM Compound: 2; 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 27322756]
HeLa	IC₅₀	14.78 μM Compound: 5-FU	Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay Antitumor activity against human HeLa cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 23313635]
HeLa	IC₅₀	14.93 μM Compound: 5-Fluoruracil	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 22555152]
HeLa	IC₅₀	142.6 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23356786]
HeLa	IC₅₀	15.02 μM Compound: 5-FLU	Cytotoxicity against human HeLa cells assessed as growth inhibition by MTT assay Cytotoxicity against human HeLa cells assessed as growth inhibition by MTT assay	[PMID: 32331934]
HeLa	IC₅₀	15.5 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
HeLa	IC₅₀	15.69 μM Compound: 1; 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 1.5 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 1.5 hrs by CCK-8 assay	[PMID: 38107178]
HeLa	IC₅₀	15.99 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 22687745]
HeLa	IC₅₀	16 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 3 days by MTT assay Antiproliferative activity against human HeLa cells after 3 days by MTT assay	[PMID: 18424155]
HeLa	IC₅₀	16.1 μM Compound: 5-FU	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 21515044]
HeLa	IC₅₀	16.32 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 24 hrs by MTT assay Cytotoxicity against human HeLa cells after 24 hrs by MTT assay	[PMID: 22182926]
HeLa	IC₅₀	16.32 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay Cytotoxicity against human HeLa cells by after 48 hrs by MTT assay	[PMID: 22579780]
HeLa	IC₅₀	16.32 μM Compound: 5-Fu	Growth inhibition of human HeLa cells after 48 hrs by MTT assay Growth inhibition of human HeLa cells after 48 hrs by MTT assay	[PMID: 23353737]
HeLa	IC₅₀	16.52 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23920246]
HeLa	IC₅₀	17.21 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells after 48 hrs by CCK-8 assay	[PMID: 27542307]
HeLa	IC₅₀	17.21 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay	[PMID: 26786698]
HeLa	IC₅₀	17.35 μM Compound: 1; 5-FU	Growth inhibition of human HeLa cells incubated for 1.5 hrs by MTT assay Growth inhibition of human HeLa cells incubated for 1.5 hrs by MTT assay	[PMID: 38107178]
HeLa	IC₅₀	18.1 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
HeLa	IC₅₀	18.82 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 37859725]
HeLa	IC₅₀	2.3 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24547794]
HeLa	IC₅₀	2.6 μM Compound: 5-FU	Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting Cytostatic activity against human HeLa cells after 72 hrs by Coulter counting	[PMID: 25435471]
HeLa	IC₅₀	2.78 μM Compound: FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24941129]
HeLa	IC₅₀	2.9 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 28838694]
HeLa	IC₅₀	20.4 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human HeLa cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
HeLa	IC₅₀	20.6 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
HeLa	IC₅₀	23.33 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24953029]
HeLa	IC₅₀	24.34 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by SRB assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by SRB assay	[PMID: 35594653]
HeLa	IC₅₀	26.18 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HeLa	IC₅₀	28 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability by MTT assay	[PMID: 29489361]
HeLa	IC₅₀	28.2 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27561718]
HeLa	IC₅₀	28.22 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
HeLa	IC₅₀	3.25 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT method Antiproliferative activity against human HeLa cells after 48 hrs by MTT method	[PMID: 23018096]
HeLa	IC₅₀	3.2 μg/mL Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
HeLa	IC₅₀	3.4 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 23792763]
HeLa	IC₅₀	3.82 μg/mL Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 29100732]
HeLa	IC₅₀	30.2 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 29305189]
HeLa	IC₅₀	30.21 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 30007564]
HeLa	IC₅₀	30.71 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth by MTT assay	[PMID: 36089111]
HeLa	IC₅₀	32.1 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 34883453]
HeLa	IC₅₀	35.34 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24378217]
HeLa	IC₅₀	35.34 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 25151580]
HeLa	IC₅₀	36.53 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 25462253]
HeLa	IC₅₀	3 μg/mL Compound: 5-Fluorouracil	In vitro inhibitory concentration for cytotoxic activity was tested against HeLa cells In vitro inhibitory concentration for cytotoxic activity was tested against HeLa cells	10.1016/S0960-894X(97)00365-X
HeLa	IC₅₀	4 μM Compound: 5-FU	Growth inhibition of human HeLa cells after 72 hrs by MTT assay Growth inhibition of human HeLa cells after 72 hrs by MTT assay	[PMID: 18640746]
HeLa	IC₅₀	4 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 3 days by MTT assay Cytotoxicity against human HeLa cells after 3 days by MTT assay	[PMID: 21612935]
HeLa	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells by MTT assay Antiproliferative activity against human HeLa cells by MTT assay	[PMID: 31546197]
HeLa	IC₅₀	4.6 μM Compound: 5-Fluorouracil	Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Anticancer activity against human HeLa cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
HeLa	IC₅₀	4.71 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
HeLa	IC₅₀	4.9 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human HeLa cells after 48 hrs by sulforhodamine B assay	[PMID: 24910974]
HeLa	IC₅₀	41.46 μM Compound: 5-Fu	Antitumor activity against human HeLa cells after 72 hrs by MTT assay Antitumor activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 21486694]
HeLa	IC₅₀	42.74 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
HeLa	IC₅₀	43 μM Compound: 5-fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 22304344]
HeLa	IC₅₀	43.71 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 23665106]
HeLa	IC₅₀	43.71 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay Antiproliferative activity against human HeLa cells after 72 hrs by MTS assay	[PMID: 26703795]
HeLa	IC₅₀	49.77 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as cell growth inhibition Cytotoxicity against human HeLa cells assessed as cell growth inhibition	[PMID: 35809817]
HeLa	IC₅₀	5.3 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
HeLa	IC₅₀	5.78 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
HeLa	IC₅₀	5.7 μg/mL Compound: 5-Fu	Anticancer activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
HeLa	IC₅₀	5.8 μM Compound: 5-FU	Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay Antiproliferation activity against human HeLa cells assessed as reduction in cell viability after 72 hrs by WST-8 assay	[PMID: 27311895]
HeLa	IC₅₀	5.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay Antiproliferative activity against human HeLa cells after 72 hrs by WST8 assay	[PMID: 25919052]
HeLa	IC₅₀	50 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 31057737]
HeLa	IC₅₀	56.5 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by MTT assay	10.1039/C6MD00234J
HeLa	IC₅₀	57.17 μM Compound: 5-Fu	Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells measured after 48 hrs by MTT assay	[PMID: 27287368]
HeLa	IC₅₀	6.23 μM Compound: FUra	Cytotoxicity against human HeLa cells after 72 hrs by SRB assay Cytotoxicity against human HeLa cells after 72 hrs by SRB assay	[PMID: 23867603]
HeLa	IC₅₀	6.23 μM Compound: FUra	Cytotoxicity against human HeLa cells after 72 hrs by SRB assay Cytotoxicity against human HeLa cells after 72 hrs by SRB assay	[PMID: 27073055]
HeLa	IC₅₀	6.23 μM Compound: FUra	Cytotoxicity against human HeLa cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human HeLa cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
HeLa	IC₅₀	6.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay Antiproliferative activity against human HeLa cells after 72 hrs by WST-8 assay	[PMID: 26606140]
HeLa	IC₅₀	62.2 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 48 hrs by MTS assay Antiproliferative activity against human HeLa cells after 48 hrs by MTS assay	[PMID: 28152430]
HeLa	IC₅₀	63.4 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23067549]
HeLa	IC₅₀	64.2 μM Compound: 5-Fu	Antitumor activity against human HeLa cells by MTT assay Antitumor activity against human HeLa cells by MTT assay	[PMID: 20171096]
HeLa	IC₅₀	66.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
HeLa	IC₅₀	6 μg Compound: 5-fluorouracil	Compound was tested in vitro for cytotoxicity against HeLa cells. Compound was tested in vitro for cytotoxicity against HeLa cells.	[PMID: 8709115]
HeLa	IC₅₀	7 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 29908443]
HeLa	IC₅₀	7.34 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23558238]
HeLa	IC₅₀	7.34 μM Compound: 5-Fu	Growth inhibition against human HeLa cells after 48 hrs by MTT assay Growth inhibition against human HeLa cells after 48 hrs by MTT assay	[PMID: 23999046]
HeLa	IC₅₀	7.34 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 2 days by MTT assay Cytotoxicity against human HeLa cells after 2 days by MTT assay	[PMID: 24767839]
HeLa	IC₅₀	7.79 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay	[PMID: 38626522]
HeLa	IC₅₀	8.317 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 26301558]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 27875779]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 28525845]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 29133046]
HeLa	IC₅₀	8.81 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HeLa cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
HeLa	IC₅₀	8.93 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
HeLa	IC₅₀	80.48 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 24565905]
HeLa	IC₅₀	82.2 μM Compound: 5-Fu	Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay Cytotoxicity against human HeLa cells after 48 hrs by CCK-8 assay	[PMID: 22244588]
HeLa	IC₅₀	82.27 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
HeLa	IC₅₀	9.02 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay Antiproliferative activity against human HeLa cells after 48 hrs by MTT assay	[PMID: 28363444]
HeLa	IC₅₀	9.09 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 25529742]
HeLa	IC₅₀	9.5 μM Compound: 5-fluorouracil	Cytotoxicity against human HeLa cells after 48 hrs by MTT assay Cytotoxicity against human HeLa cells after 48 hrs by MTT assay	[PMID: 23002924]
HeLa	IC₅₀	9.7 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay Cytotoxicity against Homo sapiens (human) HeLa cells by MTT assay	10.1007/s00044-010-9395-1
HeLa	IC₅₀	9.7 μM Compound: 5-FU	Cytotoxicity against human HeLa cells after 72 hrs by MTT assay Cytotoxicity against human HeLa cells after 72 hrs by MTT assay	[PMID: 20494492]
HeLa	IC₅₀	9.75 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human HeLa cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 39016216]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human HeLa cells after 72 hrs Antiproliferative activity against p53 deficient human HeLa cells after 72 hrs	[PMID: 18469809]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient HeLa cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient HeLa cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human HeLa cells by MTT assay Cytotoxicity against human HeLa cells by MTT assay	[PMID: 21689869]
HeLa	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay	[PMID: 26617970]
HeLa	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
HeLa	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
HeLa	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human HeLa cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
HeLa	IC₅₀	1.0 x 10^-6 M Compound: 5-Fu	Inhibitory concentration against Hella cancer cell lines was determined. Inhibitory concentration against Hella cancer cell lines was determined.	[PMID: 11229742]
HeLa S3	ED₅₀	2.47 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HeLaS3 cells after 3 days by trypan blue exclusion technique Cytotoxicity against human HeLaS3 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
HeLa S3	IC₅₀	5.4 μM Compound: Fluorouracil	Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay Cytotoxicity against human HeLaS3 cells after 72 hrs by WST1 assay	[PMID: 15387656]
HeLa S3	IC₅₀	5.4 μM Compound: fluorouracil	Cytotoxicity against human HeLaS3 cells by WST1 assay Cytotoxicity against human HeLaS3 cells by WST1 assay	[PMID: 15568771]
Hep 3B2	ED₅₀	0.6 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 16309328]
Hep 3B2	ED₅₀	7.15 x 10^-2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 11908984]
Hep 3B2	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human Hep 3B cells by MTT microassay Cytotoxicity against human Hep 3B cells by MTT microassay	[PMID: 17320246]
Hep 3B2	IC₅₀	0.6 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 18606546]
Hep 3B2	IC₅₀	1.5 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human Hep3B cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
Hep 3B2	IC₅₀	10.53 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay	[PMID: 26883148]
Hep 3B2	IC₅₀	10.53 μM Compound: 5-Fu	Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxic activity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27993516]
Hep 3B2	IC₅₀	10.53 μM Compound: 5FU	Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human Hep3B cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
Hep 3B2	IC₅₀	11.9 μM Compound: 5-FU	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 28371676]
Hep 3B2	IC₅₀	17.53 μM Compound: 5-Fu	Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells after 48 hrs by MTT assay	[PMID: 27133593]
Hep 3B2	IC₅₀	2.66 μM Compound: 5-FU	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 28262527]
Hep 3B2	IC₅₀	22.99 μM Compound: 5-Fluorouracil	Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
Hep 3B2	IC₅₀	49.72 μM Compound: 5-FU	Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human Hep3B cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 28174107]
Hep 3B2	IC₅₀	5.11 μM Compound: 5-FU	Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay Antiproliferative activity against human Hep3B cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay	[PMID: 38626522]
Hep 3B2	IC₅₀	7.2 x 10^-2 μg/mL Compound: 5-Fu	Cytotoxicity against human Hep3B cells by MTT assay Cytotoxicity against human Hep3B cells by MTT assay	[PMID: 16038565]
Hep 3B2	IC₅₀	9.36 μM Compound: 5-Fluorouracil	Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human Hep3B cells assessed as cell growth inhibition by MTT assay	[PMID: 27913179]
HepG2	EC₅₀	2.21 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 26883149]
HepG2	EC₅₀	23.31 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 21889345]
HepG2	EC₅₀	52.43 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 20409617]
HepG2	ED₅₀	3.3 x 10^-2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 11908984]
HepG2	GI₅₀	7 μM Compound: 5-FU	Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay Hepatotoxicity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 27688184]
HepG2	IC₅₀	0.004 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition Cytotoxicity against human HepG2 cells assessed as cell growth inhibition	[PMID: 35964428]
HepG2	IC₅₀	0.061 mM Compound: 5-Fluorouracil	Cytotoxicity in human HepG2 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human HepG2 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
HepG2	IC₅₀	0.07 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
HepG2	IC₅₀	0.178 μM Compound: 5-FU	Anticancer activity against human HepG2 cells incubated for 72 hrs by MTT assay Anticancer activity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 36921275]
HepG2	IC₅₀	0.37 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 37360398]
HepG2	IC₅₀	0.52 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 32485532]
HepG2	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method Antiproliferative activity against human HepG2 cells after 48 hrs by MTT method	[PMID: 23018096]
HepG2	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
HepG2	IC₅₀	1.3 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 16499328]
HepG2	IC₅₀	1.4 μM Compound: 5-F	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 28254697]
HepG2	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
HepG2	IC₅₀	1.7 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 29798826]
HepG2	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
HepG2	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23800391]
HepG2	IC₅₀	10.17 μM Compound: 5FU	Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human HepG2 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
HepG2	IC₅₀	10.3 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	10.1039/C6MD00169F
HepG2	IC₅₀	10.36 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 34655985]
HepG2	IC₅₀	10.4 μM Compound: 5-Fu	Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
HepG2	IC₅₀	10.45 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 22801644]
HepG2	IC₅₀	10.53 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 28174107]
HepG2	IC₅₀	108 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 22283451]
HepG2	IC₅₀	109 μM Compound: Fluorouracil	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 21774474]
HepG2	IC₅₀	11.68 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
HepG2	IC₅₀	11.68 μM Compound: 5-Fu	Antitumor activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36931124]
HepG2	IC₅₀	110.01 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 21962523]
HepG2	IC₅₀	112.1 μM Compound: 5-FU	Cytotoxicity in human HePG2 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human HePG2 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
HepG2	IC₅₀	12 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 6 days by MTT assay Cytotoxicity against human HepG2 cells after 6 days by MTT assay	[PMID: 29786436]
HepG2	IC₅₀	12.48 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay Cytotoxicity against human HepG2 cells after 48 hrs by CCK-8 assay	[PMID: 24013415]
HepG2	IC₅₀	12.94 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 39016216]
HepG2	IC₅₀	13.31 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28363444]
HepG2	IC₅₀	13.54 μM Compound: 2; 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27322756]
HepG2	IC₅₀	14.52 μM Compound: 2; 5-FU	Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
HepG2	IC₅₀	15.74 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay Antiproliferative activity against human HepG2 cells after 24 hrs by CCK-8 assay	[PMID: 29499490]
HepG2	IC₅₀	15.8 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as cell inhibition measured after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell inhibition measured after 72 hrs by MTT assay	[PMID: 36774698]
HepG2	IC₅₀	15.92 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22209486]
HepG2	IC₅₀	15.92 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 30359819]
HepG2	IC₅₀	16.42 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 26227777]
HepG2	IC₅₀	16.42 μM Compound: 5-fluorouracil	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 37859723]
HepG2	IC₅₀	17.2 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 28117202]
HepG2	IC₅₀	17.44 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
HepG2	IC₅₀	17.57 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
HepG2	IC₅₀	174.5 μM Compound: 5-Fuorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27017265]
HepG2	IC₅₀	18.35 μM Compound: 2; 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29202398]
HepG2	IC₅₀	18.7 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 18302336]
HepG2	IC₅₀	18.85 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 after 48 hrs by MTT assay Cytotoxicity against human HepG2 after 48 hrs by MTT assay	[PMID: 21486698]
HepG2	IC₅₀	18.9 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
HepG2	IC₅₀	18.98 μM Compound: 5-FU	Anticancer activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Anticancer activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34425478]
HepG2	IC₅₀	18.98 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 35609396]
HepG2	IC₅₀	19.2 μM Compound: 5-FU	Antitumor activity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell viability after 72 hr by MTT assay Antitumor activity against Homo sapiens (human) HepG2 cells assessed as inhibition of cell viability after 72 hr by MTT assay	10.1007/s00044-012-0283-8
HepG2	IC₅₀	19.45 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 24211021]
HepG2	IC₅₀	2.1 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 28262527]
HepG2	IC₅₀	2.24 μg/mL Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 29100732]
HepG2	IC₅₀	2.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
HepG2	IC₅₀	2.7 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 3 days by MTT assay Cytotoxicity against human HepG2 cells after 3 days by MTT assay	[PMID: 22000925]
HepG2	IC₅₀	2.78 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 21131104]
HepG2	IC₅₀	2.88 μM Compound: 5-FU	Antitumor activity against human HepG2 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human HepG2 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
HepG2	IC₅₀	2.98 μM Compound: 5-Fu	Antiproliferation activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
HepG2	IC₅₀	20.1 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28400238]
HepG2	IC₅₀	20.4 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
HepG2	IC₅₀	205.19 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as reduction in cell growth after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell growth after 48 hrs by MTT assay	[PMID: 27422336]
HepG2	IC₅₀	21.9 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 23279864]
HepG2	IC₅₀	22.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23490159]
HepG2	IC₅₀	23.45 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by CCK-8 assay	[PMID: 38784474]
HepG2	IC₅₀	23.6 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29486954]
HepG2	IC₅₀	237 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
HepG2	IC₅₀	24.733 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 39163776]
HepG2	IC₅₀	24.96 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 23685571]
HepG2	IC₅₀	25.17 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27133593]
HepG2	IC₅₀	25.48 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 48 hrs by MTT assay	[PMID: 37972528]
HepG2	IC₅₀	25 μg/mL Compound: 5FU	Cytotoxicity against human HepG2 cells after 48 hrs by SRB assay Cytotoxicity against human HepG2 cells after 48 hrs by SRB assay	[PMID: 21115211]
HepG2	IC₅₀	26.34 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 34655985]
HepG2	IC₅₀	26.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24565905]
HepG2	IC₅₀	28.8 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28756264]
HepG2	IC₅₀	29.07 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 28458133]
HepG2	IC₅₀	29.1 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 28494251]
HepG2	IC₅₀	29.38 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 37182331]
HepG2	IC₅₀	29.81 μM Compound: 5-Fu	Antitumor activity human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity human HepG2 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36216031]
HepG2	IC₅₀	29.87 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 23202484]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23988357]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 3 days by MTT assay Cytotoxicity against human HepG2 cells after 3 days by MTT assay	[PMID: 24095745]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24378217]
HepG2	IC₅₀	29.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 25151580]
HepG2	IC₅₀	3.09 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells incubated for 72 hrs by SRB method Antiproliferative activity against human HepG2 cells incubated for 72 hrs by SRB method	[PMID: 39054645]
HepG2	IC₅₀	3.6 μM Compound: Fluorouracil	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
HepG2	IC₅₀	30.48 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
HepG2	IC₅₀	30.79 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
HepG2	IC₅₀	30.8 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30527868]
HepG2	IC₅₀	31.7 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30739827]
HepG2	IC₅₀	31.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30092368]
HepG2	IC₅₀	31.98 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30108826]
HepG2	IC₅₀	31.98 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 2 days by MTT assay Cytotoxicity against human HepG2 cells after 2 days by MTT assay	[PMID: 25841196]
HepG2	IC₅₀	32.22 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22687745]
HepG2	IC₅₀	32.57 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
HepG2	IC₅₀	32.57 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
HepG2	IC₅₀	32.6 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 28371676]
HepG2	IC₅₀	32.6 μM Compound: 5-Fu	Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxic activity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27993516]
HepG2	IC₅₀	32.87 μM Compound: 5-FU	Growth inhibition of human HepG2 cells after 24 hrs by MTT assay Growth inhibition of human HepG2 cells after 24 hrs by MTT assay	[PMID: 28011220]
HepG2	IC₅₀	33.5 μg/mL Compound: 5-FU	Anticancer activity against human HepG2 cells Anticancer activity against human HepG2 cells	[PMID: 32795767]
HepG2	IC₅₀	33.68 μM Compound: 5-fluorouracil	Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell growth inhibition by MTT assay	[PMID: 31945642]
HepG2	IC₅₀	33.79 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells by CCK8 assay Antiproliferative activity against human HepG2 cells by CCK8 assay	[PMID: 37939862]
HepG2	IC₅₀	34 μM Compound: 5-fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22304344]
HepG2	IC₅₀	35.99 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 26546214]
HepG2	IC₅₀	36.1 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay	[PMID: 36288556]
HepG2	IC₅₀	36.6 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29305189]
HepG2	IC₅₀	36.62 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30007564]
HepG2	IC₅₀	36.74 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
HepG2	IC₅₀	37.9 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against HepG2 cells Tested in vitro for anticancer activity against HepG2 cells	[PMID: 10072683]
HepG2	IC₅₀	38.34 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24953029]
HepG2	IC₅₀	39.74 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
HepG2	IC₅₀	4.07 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay	[PMID: 38626522]
HepG2	IC₅₀	4.35 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24119869]
HepG2	IC₅₀	4.8 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22727445]
HepG2	IC₅₀	40.18 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
HepG2	IC₅₀	40.34 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
HepG2	IC₅₀	40.34 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23558238]
HepG2	IC₅₀	40.34 μM Compound: 5-Fu	Growth inhibition against human HepG2 cells after 48 hrs by MTT assay Growth inhibition against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23999046]
HepG2	IC₅₀	40.34 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human HepG2 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
HepG2	IC₅₀	41.62 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
HepG2	IC₅₀	46.31 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22483608]
HepG2	IC₅₀	46.83 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 26363869]
HepG2	IC₅₀	46.83 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells measured after 48 hrs by MTT assay	[PMID: 27287368]
HepG2	IC₅₀	46.83 μM Compound: Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 22809558]
HepG2	IC₅₀	46.83 μM Compound: Fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 25016234]
HepG2	IC₅₀	46.83 μM Compound: Fluorouracil	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 27128180]
HepG2	IC₅₀	47.97 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 30142612]
HepG2	IC₅₀	49.02 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
HepG2	IC₅₀	49.02 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 28110871]
HepG2	IC₅₀	49.72 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 26883148]
HepG2	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 27987485]
HepG2	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay Antiproliferative activity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 29326016]
HepG2	IC₅₀	5 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 22409771]
HepG2	IC₅₀	5.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
HepG2	IC₅₀	5.3 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 34655985]
HepG2	IC₅₀	5.46 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38677112]
HepG2	IC₅₀	5.7 μM Compound: 5FU	Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HepG2 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
HepG2	IC₅₀	5.82 μM Compound: 5-FU	Antiproliferative activity in human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity in human HepG2 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
HepG2	IC₅₀	5.86 μM Compound: 5-Fluorouracil	Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human HepG2 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
HepG2	IC₅₀	51.5 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 23067549]
HepG2	IC₅₀	55.2 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
HepG2	IC₅₀	55.74 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
HepG2	IC₅₀	56.2 μM Compound: 5-Fluoruracil	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22555152]
HepG2	IC₅₀	59.12 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 29958763]
HepG2	IC₅₀	6.6 μM Compound: FUra	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 27073055]
HepG2	IC₅₀	6.6 μM Compound: FUra	Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human HepG2 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
HepG2	IC₅₀	6.69 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
HepG2	IC₅₀	6.9 μM Compound: 5-Fluorouracil	Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
HepG2	IC₅₀	60.73 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay Cytotoxicity against human HepG2 cells after 24 hrs by MTT assay	[PMID: 31401008]
HepG2	IC₅₀	63.37 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 30108924]
HepG2	IC₅₀	66.42 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 30826506]
HepG2	IC₅₀	66.42 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 33831559]
HepG2	IC₅₀	66.82 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 37859725]
HepG2	IC₅₀	68 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 31057737]
HepG2	IC₅₀	7.22 μM Compound: 5-Fluorouracil	Antiproliferative activity against human HepG2 cells by MTT assay Antiproliferative activity against human HepG2 cells by MTT assay	[PMID: 31546197]
HepG2	IC₅₀	7.43 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24286761]
HepG2	IC₅₀	7.6 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 24547794]
HepG2	IC₅₀	7.9 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 31761383]
HepG2	IC₅₀	72.33 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition measured after 72 hrs by MTT assay	[PMID: 34838335]
HepG2	IC₅₀	76.7 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells after 2 days by alamar blue assay Cytotoxicity against human HepG2 cells after 2 days by alamar blue assay	[PMID: 22093761]
HepG2	IC₅₀	76.9 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability by MTT assay Cytotoxicity against human HepG2 cells assessed as decrease in cell viability by MTT assay	[PMID: 29489361]
HepG2	IC₅₀	8 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27343853]
HepG2	IC₅₀	8 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay	[PMID: 25969171]
HepG2	IC₅₀	8.02 μM Compound: 5-fluorouracil	Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of cell growth by MTT assay	[PMID: 31884408]
HepG2	IC₅₀	8.1 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 28431341]
HepG2	IC₅₀	8.2 x 10^-3 μg/mL Compound: fluorouracil	Cytotoxicity against human HepG2 cells by MTT assay Cytotoxicity against human HepG2 cells by MTT assay	[PMID: 22011319]
HepG2	IC₅₀	8.66 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
HepG2	IC₅₀	8.69 μM Compound: 5-Fu	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 32791397]
HepG2	IC₅₀	8.6 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against human HepG2 cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
HepG2	IC₅₀	8.6 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 22204901]
HepG2	IC₅₀	8.6 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human HepG2 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
HepG2	IC₅₀	8.8 μM Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31276896]
HepG2	IC₅₀	8.9 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 27875779]
HepG2	IC₅₀	8.9 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 28525845]
HepG2	IC₅₀	8.9 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
HepG2	IC₅₀	85 μM Compound: 5-flurouracil	Compound was evaluated for the inhibition of cell proliferation of human hepatocellular carcinoma, HepG2 (ATCC HB8065). Compound was evaluated for the inhibition of cell proliferation of human hepatocellular carcinoma, HepG2 (ATCC HB8065).	10.1016/0960-894X(96)00418-0
HepG2	IC₅₀	86.87 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition by MTT assay	[PMID: 24684840]
HepG2	IC₅₀	9.1 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay Cytotoxicity against human HepG2 cells after 96 hrs by MTT assay	[PMID: 23022735]
HepG2	IC₅₀	9.2 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells after 3 days by MTT assay Antiproliferative activity against human HepG2 cells after 3 days by MTT assay	[PMID: 18424155]
HepG2	IC₅₀	9.23 μg/mL Compound: 5-Fu	Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
HepG2	IC₅₀	9.3 μg/mL Compound: 5-FU	Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells after 72 hrs by MTT assay	[PMID: 22647218]
HepG2	IC₅₀	> 10 μM Compound: 5-FU	Growth inhibition of human HepG2 cells after 72 hrs by MTS assay Growth inhibition of human HepG2 cells after 72 hrs by MTS assay	[PMID: 27704811]
HepG2	IC₅₀	> 100 μM Compound: 5-FU	Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay Antitumor activity against human HepG2 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 23313635]
HepG2	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human HepG2 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
HepG2	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay	[PMID: 37659196]
HepG2	IC₅₀	> 150 μM Compound: 5-FU	Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26320625]
HepG2	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human HepG2 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
Hs-578T	GI₅₀	9.77 μM Compound: 5-FU	Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay Growth inhibition of human Hs 578T cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
Hs-578T	GI₅₀	9.77 μM Compound: 5-FU	Anticancer activity against human Hs-578T cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human Hs-578T cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
Hs-578T	IC₅₀	9.77 μM Compound: 5-Fluorouracil	Cytotoxicity against human Hs-578T cells assessed as cell growth inhibition Cytotoxicity against human Hs-578T cells assessed as cell growth inhibition	[PMID: 36470105]
HuTu80	GI₅₀	0.4 μg/mL Compound: 5FU	Cytotoxicity against human HuTu 80 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human HuTu 80 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
HuTu80	IC₅₀	65.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human HuTu80 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human HuTu80 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
Huh-7	IC₅₀	1.06 μM Compound: 5-FU	Anticancer activity against human Huh-7 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human Huh-7 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
Huh-7	IC₅₀	10.41 μg/mL Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 26546214]
Huh-7	IC₅₀	15.85 μM Compound: 5-Fu	Growth inhibition of human HuH7 cells after 48 hrs by MTT assay Growth inhibition of human HuH7 cells after 48 hrs by MTT assay	[PMID: 23353737]
Huh-7	IC₅₀	2.98 mM Compound: 5-FU	Antiproliferative activity against human HuH7 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Antiproliferative activity against human HuH7 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 28073674]
Huh-7	IC₅₀	20.03 μg/mL Compound: 5-F	Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay Cytotoxicity against human HuH7 cells after 48 hrs by MTT assay	[PMID: 24342667]
Huh-7	IC₅₀	21 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
Huh-7	IC₅₀	21 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 30108969]
Huh-7	IC₅₀	28.53 μM Compound: 5-Fu	Cytotoxicity against human Huh-7 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human Huh-7 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 38964974]
Huh-7	IC₅₀	30 μM Compound: 5-FU	Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay Antiproliferative activity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 29326016]
Huh-7	IC₅₀	30.3 μM Compound: 5-Fu	Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay Antiproliferative activity against human Huh-7 cells assessed as reduction in cell viability after 48 hr by CCK-8 assay	[PMID: 36288556]
Huh-7	IC₅₀	30.6 μM Compound: 5-FU	Cytotoxicity against human Huh-7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay Cytotoxicity against human Huh-7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay	[PMID: 38688437]
Huh-7	IC₅₀	30.7 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 25462277]
Huh-7	IC₅₀	30.7 μM Compound: 5-FU	Cytotoxicity against human Huh-7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay Cytotoxicity against human Huh-7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay	[PMID: 38107180]
Huh-7	IC₅₀	30.7 μM Compound: 5-Fu	Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay Cytotoxicity against human HuH7 cells after 72 hrs by SRB assay	[PMID: 22409771]
Huh-7	IC₅₀	30.7 μM Compound: 5FU	Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay Cytotoxicity against human HuH7 cells assessed as inhibition of cell proliferation by sulforhodamine B assay	10.1039/C4MD00306C
Huh-7	IC₅₀	30.7 μM Compound: 5FU	Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human HuH7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
Huh-7	IC₅₀	390 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as reduction in cell growth after 48 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as reduction in cell growth after 48 hrs by MTT assay	[PMID: 27422336]
Huh-7	IC₅₀	5.63 μM Compound: 5-FU	Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay Antiproliferative activity against human HuH7 cells after 72 hrs by MTT assay	[PMID: 29316536]
Huh-7	IC₅₀	8.98 μM Compound: 5-FU	Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human Huh-7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 37182331]
Huh-7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HuH7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26320625]
IEC-6	IC₅₀	0.66 μM Compound: 5-FU	Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay Cytotoxicity against rat IEC-6 cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
IGROV-1	GI₅₀	1.22 μM Compound: 5-FU	Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human IGROV1 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
IGROV-1	GI₅₀	1.22 μM Compound: 5-FU	Anticancer activity against human IGROV-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human IGROV-1 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
IGROV-1	GI₅₀	8.12 nM Compound: 5FU	Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay	[PMID: 23094992]
IGROV-1	GI₅₀	9.1 μM Compound: 5-Fu	Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay Growth inhibition of human IGROV1 cells after 48 hrs by SRB assay	[PMID: 22512908]
IGROV-1	IC₅₀	1.22 μM Compound: 5-Fluorouracil	Cytotoxicity against human IGROV-1 cells assessed as cell growth inhibition Cytotoxicity against human IGROV-1 cells assessed as cell growth inhibition	[PMID: 36470105]
IGROV-1	IC₅₀	10.6 μM Compound: 5FU	Cytotoxicity against human IGROV1 cells after 72 hrs Cytotoxicity against human IGROV1 cells after 72 hrs	[PMID: 30035541]
IM-9	IC₅₀	0.34 μg/mL Compound: 5-F-Ura	In vitro antitumor activity in IM-9 cell lines In vitro antitumor activity in IM-9 cell lines	[PMID: 8648611]
IMR-32	IC₅₀	1.3 μM Compound: 5-FU	Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay	[PMID: 25176329]
IMR-32	IC₅₀	1.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay Cytotoxicity against human IMR32 cells after 48 hrs by SRB assay	[PMID: 24056146]
IMR-32	IC₅₀	18 μM Compound: 5-fluorouracil	Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human IMR32 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
IMR-32	IC₅₀	5.7 μM Compound: 5-fluorouracil	Cytotoxicity against human IMR32 cells after 48 hrs by CellTiter-Glo assay Cytotoxicity against human IMR32 cells after 48 hrs by CellTiter-Glo assay	[PMID: 31999116]
IMR-90	IC₅₀	136.4 μM Compound: 5-Fluorouracil	Cytotoxicity against human IMR90 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human IMR90 cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
Ishikawa	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human Ishikawa cells assessed as reduction in cell viability Antiproliferative activity against human Ishikawa cells assessed as reduction in cell viability	[PMID: 38911148]
Jurkat	IC₅₀	87 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient Jurkat cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient Jurkat cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
Jurkat	IC₅₀	87.73 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human Jurkat cells after 72 hrs by proliferative assay Antiproliferative activity against p53 deficient human Jurkat cells after 72 hrs by proliferative assay	[PMID: 18469809]
K562	ED₅₀	16.22 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells after 6 hrs by Alamar Blue assay Cytotoxicity against human K562 cells after 6 hrs by Alamar Blue assay	[PMID: 24020806]
K562	ED₅₀	21 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells by Alamar blue assay Cytotoxicity against human K562 cells by Alamar blue assay	[PMID: 24128077]
K562	GI₅₀	0.9 μg/mL Compound: 5FU	Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
K562	GI₅₀	16.7 μM Compound: 5FU	Cytotoxicity against human K562 cells after 48 hrs Cytotoxicity against human K562 cells after 48 hrs	[PMID: 18798609]
K562	GI₅₀	18.5 μM Compound: 5-FU	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 29040954]
K562	GI₅₀	19 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 28763647]
K562	GI₅₀	3.58 μM Compound: 5-FU	Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human K562 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
K562	GI₅₀	3.58 μM Compound: 5-FU	Anticancer activity against human K562 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human K562 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
K562	GI₅₀	89.9 μM Compound: 5FU	Cytotoxicity against human K562 cells Cytotoxicity against human K562 cells	[PMID: 20356752]
K562	IC₅₀	114.5 μM Compound: 5-Fu	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 23356786]
K562	IC₅₀	12.21 μM Compound: 5-FU	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 30677614]
K562	IC₅₀	126 μM Compound: 5-Fluorouracil	Antileukemic activity against human K562 cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human K562 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
K562	IC₅₀	126 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells Cytotoxicity against human K562 cells	[PMID: 16996657]
K562	IC₅₀	2.1 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 22537362]
K562	IC₅₀	2.2 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human chronic myelogenous leukemia (K562 cells In vitro inhibitory activity against growth of Human chronic myelogenous leukemia (K562 cells	[PMID: 1995901]
K562	IC₅₀	2.4 μM Compound: 5-FU	Anticancer activity against human K562 cells Anticancer activity against human K562 cells	[PMID: 21449610]
K562	IC₅₀	2.4 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells Cytotoxicity against human K562 cells	[PMID: 22409967]
K562	IC₅₀	20.21 μM Compound: 5-FU	Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human K562 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
K562	IC₅₀	20.7 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells after 48 hrs by MTT assay Antiproliferative activity against human K562 cells after 48 hrs by MTT assay	[PMID: 30737134]
K562	IC₅₀	23.55 μM Compound: 5-Fu	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 23558238]
K562	IC₅₀	23.55 μM Compound: 5-Fu	Growth inhibition against human K562 cells after 48 hrs by MTT assay Growth inhibition against human K562 cells after 48 hrs by MTT assay	[PMID: 23999046]
K562	IC₅₀	28 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 23535322]
K562	IC₅₀	3.54 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells after 72 hrs by MTT assay Antiproliferative activity against human K562 cells after 72 hrs by MTT assay	[PMID: 28165738]
K562	IC₅₀	3.58 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells assessed as cell growth inhibition Cytotoxicity against human K562 cells assessed as cell growth inhibition	[PMID: 36470105]
K562	IC₅₀	3.86 μM Compound: 5-FU	Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
K562	IC₅₀	3.8 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of cell growth of K562 leukemic cell lines in human. Concentration required for 50% inhibition of cell growth of K562 leukemic cell lines in human.	[PMID: 1992123]
K562	IC₅₀	3.94 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
K562	IC₅₀	3.94 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
K562	IC₅₀	30.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against human K562 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
K562	IC₅₀	31.6 μM Compound: 5-Fu	Anticancer activity against human K562 cells after 48 hrs by MTT assay Anticancer activity against human K562 cells after 48 hrs by MTT assay	[PMID: 25462264]
K562	IC₅₀	32.92 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells by disk diffusion soft agar colony formation assay Cytotoxicity against human K562 cells by disk diffusion soft agar colony formation assay	[PMID: 31117520]
K562	IC₅₀	38 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 21131104]
K562	IC₅₀	38.58 μM Compound: 5-FU	Growth inhibition of human K562 cells after 48 hrs by WST1 assay Growth inhibition of human K562 cells after 48 hrs by WST1 assay	[PMID: 28126436]
K562	IC₅₀	38.58 μM Compound: 5-FU	Anticancer activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay Anticancer activity against human K562 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay	[PMID: 36481599]
K562	IC₅₀	38.58 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells assessed as inhibition of cell growth Antiproliferative activity against human K562 cells assessed as inhibition of cell growth	[PMID: 36543034]
K562	IC₅₀	38.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human K562 cells by MTT reduction assay Antiproliferative activity against human K562 cells by MTT reduction assay	[PMID: 33421712]
K562	IC₅₀	38 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of human chronic myelogenous leukemic K562 cell lines. In vitro inhibitory effect on growth of human chronic myelogenous leukemic K562 cell lines.	[PMID: 3373480]
K562	IC₅₀	4.02 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human K562 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
K562	IC₅₀	4.3 μg/mL Compound: 5-F-Ura	In vitro antitumor activity in K-562 cell lines In vitro antitumor activity in K-562 cell lines	[PMID: 8648611]
K562	IC₅₀	41.66 μM Compound: 5-FU	Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
K562	IC₅₀	45.4 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) K562 cells by MTT assay Cytotoxicity against Homo sapiens (human) K562 cells by MTT assay	10.1007/s00044-010-9395-1
K562	IC₅₀	45.4 μM Compound: 5-FU	Cytotoxicity against human K562 cells after 72 hrs by MTT assay Cytotoxicity against human K562 cells after 72 hrs by MTT assay	[PMID: 20494492]
K562	IC₅₀	5.18 μM Compound: 5-Fu	Antiproliferative activity against human K562 cells by CCK8 assay Antiproliferative activity against human K562 cells by CCK8 assay	[PMID: 37939862]
K562	IC₅₀	8.48 μg/mL Compound: 5-FU	Anti-leukemia activity in human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Anti-leukemia activity in human K562 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 30114660]
K562	IC₅₀	9.49 μM Compound: 5-fluorouracil	Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
K562	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human K562 cells after 72 hrs Antiproliferative activity against p53 deficient human K562 cells after 72 hrs	[PMID: 18469809]
K562	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human K562 cells after 48 hrs by MTT assay Cytotoxicity against human K562 cells after 48 hrs by MTT assay	[PMID: 19324555]
K562	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient K562 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient K562 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
K562	IC₅₀	> 20 μM Compound: 5-Fu	Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human K562 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
K562/Adr	IC₅₀	31.9 μM Compound: 5-FU	Cytotoxicity against human K562/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human K562/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
KB	ED₅₀	1.25 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 3 days by trypan blue exclusion technique Cytotoxicity against human KB cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
KB	GI₅₀	5.2 μM Compound: 5FU	Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay Growth inhibition of human KB cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
KB	IC₅₀	0.93 μg/mL Compound: 5FU	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 10425135]
KB	IC₅₀	1.23 μM Compound: 5-Fu	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 24953029]
KB	IC₅₀	11.9 μM Compound: 5-FU	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 21144621]
KB	IC₅₀	12.1 μg/mL Compound: 5-FU	Concentration at 50 percent inhibition of cell growth against human cancer KB cell line in vitro Concentration at 50 percent inhibition of cell growth against human cancer KB cell line in vitro	10.1016/S0960-894X(01)81041-6
KB	IC₅₀	12.1 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human oral epidermoid carcinoma (KB) cell line. In vitro inhibitory activity against Human oral epidermoid carcinoma (KB) cell line.	[PMID: 1995905]
KB	IC₅₀	12.5 μM Compound: Fluorouracil	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 21843939]
KB	IC₅₀	12.5 μM Compound: fluorouracil	Cytotoxicity against human KB cells after 72 hrs MTT assay Cytotoxicity against human KB cells after 72 hrs MTT assay	[PMID: 19846302]
KB	IC₅₀	13.4 μM Compound: 5-fu	Cytotoxicity against human KB cells after 48 hrs Cytotoxicity against human KB cells after 48 hrs	[PMID: 17000031]
KB	IC₅₀	15.9 μM Compound: Flurouracil	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 21273072]
KB	IC₅₀	2.16 μM Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 21131104]
KB	IC₅₀	2.3 μM Compound: 5-Fluorouracil	In vitro cytotoxicity against human oral epidermoid carcinoma KB cells. In vitro cytotoxicity against human oral epidermoid carcinoma KB cells.	[PMID: 10229634]
KB	IC₅₀	4.46 x 10^-3 μM Compound: Fluorouracil	Cytotoxicity against human KB cells by MTT assay Cytotoxicity against human KB cells by MTT assay	[PMID: 19345581]
KB	IC₅₀	4.46 μM Compound: Fluorouracil	Cytotoxicity against human KB cells after 3 days by MTT assay Cytotoxicity against human KB cells after 3 days by MTT assay	[PMID: 20356655]
KB	IC₅₀	4.84 μM Compound: FUra	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 23867603]
KB	IC₅₀	4.84 μM Compound: FUra	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 27073055]
KB	IC₅₀	4.84 μM Compound: FUra	Cytotoxicity against human KB cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human KB cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
KB	IC₅₀	53.52 μM Compound: 5-FU	Antiproliferative activity against human KB cells after 48 hrs by MTT assay Antiproliferative activity against human KB cells after 48 hrs by MTT assay	[PMID: 25164762]
KB	IC₅₀	6.8 μM Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 48 hrs by MTT assay Cytotoxicity against human KB cells after 48 hrs by MTT assay	[PMID: 22537362]
KB	IC₅₀	7.7 pM Compound: 5-FU	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 21640594]
KB	IC₅₀	8.1 μM Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 4 days by MTT assay Cytotoxicity against human KB cells after 4 days by MTT assay	[PMID: 24359303]
KB	IC₅₀	8.28 μM Compound: 5-FU	Cytotoxicity against human KB cells after 72 hrs by MTT assay Cytotoxicity against human KB cells after 72 hrs by MTT assay	[PMID: 22749192]
KB	IC₅₀	9 μM Compound: Fluorouracil	Cytotoxicity against human KB cells after 72 hrs ny MTT assay Cytotoxicity against human KB cells after 72 hrs ny MTT assay	[PMID: 22200404]
KB	IC₅₀	9.85 μM Compound: 5-FU	Antiproliferative activity against human KB cells after 72 hrs by MTT assay Antiproliferative activity against human KB cells after 72 hrs by MTT assay	[PMID: 22079378]
KB	IC₅₀	> 10 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human KB cells after 2 to 7 days by neutral red assay Cytotoxicity against human KB cells after 2 to 7 days by neutral red assay	[PMID: 11374943]
KB	IC₅₀	3.5 x 10^-6 M Compound: 5-Fu	Inhibitory concentration against KB cancer cell lines was determined. Inhibitory concentration against KB cancer cell lines was determined.	[PMID: 11229742]
KCL-22	IC₅₀	3.52 μM Compound: FU	Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay Antiproliferative activity against human KCL22 cells after 48 hrs by MTT assay	[PMID: 24941129]
KG-1	IC₅₀	82.97 μM Compound: 2; 5-FU	Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay Antiproliferative activity against human KG1 cells after 48 hrs by MTT assay	[PMID: 27322756]
KKLS	IC₅₀	6.2 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of KKLS tumor cell line from stomach. Compound was tested for its inhibitory effect on the growth of KKLS tumor cell line from stomach.	10.1016/0960-894X(96)00339-3
KM12	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
KM12	GI₅₀	0.21 μM Compound: 5-FU	Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human KM12 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
KM12	GI₅₀	0.21 μM Compound: 5-FU	Anticancer activity against human KM12 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human KM12 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
KM12	IC₅₀	0.21 μM Compound: 5-Fluorouracil	Cytotoxicity against human KM12 cells assessed as cell growth inhibition Cytotoxicity against human KM12 cells assessed as cell growth inhibition	[PMID: 36470105]
KM12	IC₅₀	12.26 μM Compound: 5-FU	Anticancer activity against human KM12 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Anticancer activity against human KM12 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34438126]
KM12	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human KM12 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
KM12	IC₅₀	7.94 μM Compound: 5-Fluorouracil	Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human KM12 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
KM12	IC₅₀	7.94 μM Compound: 5-fluorouracil	Cytotoxicity against human KM12 cells Cytotoxicity against human KM12 cells	[PMID: 16996657]
KM12	IC₅₀	8.32 μM Compound: 5-FU	Anticancer activity against human KM12 cells Anticancer activity against human KM12 cells	[PMID: 21449610]
KM12	IC₅₀	8.32 μM Compound: 5-Fluorouracil	Cytotoxicity against human KM12 cells Cytotoxicity against human KM12 cells	[PMID: 22409967]
KYSE-270	IC₅₀	7.73 μM Compound: 5-fluorouracil	Antiproliferative activity against human KYSE-270 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human KYSE-270 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 36893627]
KYSE-450	IC₅₀	32.58 μM Compound: 5-FU	Antiproliferative activity against human KYSE-450 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human KYSE-450 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38759254]
KYSE-510	IC₅₀	7.73 μM Compound: 5-fluorouracil	Antiproliferative activity against human KYSE-510 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human KYSE-510 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 36893627]
L02	IC₅₀	10.6 μM Compound: Fluorouracil	Cytotoxicity against human LO2 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human LO2 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
L02	IC₅₀	12.85 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human HL-7702 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
L02	IC₅₀	14.53 μg/mL Compound: 5-Fu	Cytotoxicity against human HL7702 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human HL7702 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
L02	IC₅₀	19.1 μM Compound: 5-FU	Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay Anti-proliferative activity against human L02 cells after 48 hrs by MTT assay	[PMID: 28947149]
L02	IC₅₀	19.12 μM Compound: 5-Fu	Cytotoxicity in human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human L02 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
L02	IC₅₀	25.9 μM Compound: 5-FU	Cytotoxicity against human L02 cells after 72 hrs by MTT assay Cytotoxicity against human L02 cells after 72 hrs by MTT assay	[PMID: 26595184]
L02	IC₅₀	25.9 μM Compound: 5-FU	Cytotoxicity against human L02 measured after 72 hrs by MTT assay Cytotoxicity against human L02 measured after 72 hrs by MTT assay	[PMID: 27537924]
L02	IC₅₀	29.53 μM Compound: 5-Fu	Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human LO2 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
L02	IC₅₀	32.546 μM Compound: 5-FU	Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay Antiproliferative activity against human LO2 cells after 72 hrs by CCK-8 assay	[PMID: 28301815]
L02	IC₅₀	44.05 μM Compound: 5-FU	Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
L02	IC₅₀	46 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay	[PMID: 28756264]
L02	IC₅₀	46.45 μM Compound: 5-FU	Cytotoxicity against human L02 cells assessed as cell growth inhibition Cytotoxicity against human L02 cells assessed as cell growth inhibition	[PMID: 35809817]
L02	IC₅₀	46.57 μM Compound: 5-Fu	Cytotoxicity against human L02 cells by after 48 hrs by MTT assay Cytotoxicity against human L02 cells by after 48 hrs by MTT assay	[PMID: 22579780]
L02	IC₅₀	46.57 μM Compound: 5-Fu	Growth inhibition of human L02 cells after 48 hrs by MTT assay Growth inhibition of human L02 cells after 48 hrs by MTT assay	[PMID: 23353737]
L02	IC₅₀	54.45 μM Compound: 5-Fu	Cytotoxicity against human L02 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Cytotoxicity against human L02 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 37360398]
L02	IC₅₀	56 μM Compound: 5-fluorouracil	Cytotoxicity against human L02 cells after 48 hrs by MTT assay Cytotoxicity against human L02 cells after 48 hrs by MTT assay	[PMID: 21131104]
L02	IC₅₀	58.74 μM Compound: 5-FU	Cytotoxicity against human HL7702 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human HL7702 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
L02	IC₅₀	58.74 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay	[PMID: 30092368]
L02	IC₅₀	58.74 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay Cytotoxicity against human HL-7702 cells after 48 hrs by MTT assay	[PMID: 30108826]
L02	IC₅₀	95.36 μM Compound: 5-FU	Cytotoxicity against human HL-7702 cells assessed as growth inhibition by MTT assay Cytotoxicity against human HL-7702 cells assessed as growth inhibition by MTT assay	[PMID: 24684840]
L02	IC₅₀	> 10 μM Compound: 5-Fu	Cytotoxicity against human LO2 cells after 48 hrs by MTT assay Cytotoxicity against human LO2 cells after 48 hrs by MTT assay	[PMID: 26714048]
L02	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay Antiproliferative activity against human L02 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay	[PMID: 37659196]
L02	IC₅₀	> 200 μM Compound: 5-FU	Cytotoxicity against human LO2 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human LO2 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
L02	IC₅₀	> 40 μM Compound: 5-Fu	Antiproliferative activity against human L02 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human L02 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
L02	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human L02 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human L02 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
L02	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human L02 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human L02 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 31877536]
L1210	ED₅₀	1.41 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse L1210 cells after 3 days by trypan blue exclusion technique Cytotoxicity against mouse L1210 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
L1210	ED₅₀	1.94 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse L1210 cells Cytotoxicity against mouse L1210 cells	[PMID: 3443857]
L1210	IC₅₀	0.02 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.04 μg/mL Compound: 5-FU	Evaluated for the inhibition of tumor cell growth of murine leukemia malignant tumor cell line (L1210/0) Evaluated for the inhibition of tumor cell growth of murine leukemia malignant tumor cell line (L1210/0)	[PMID: 11123990]
L1210	IC₅₀	0.06 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.12 μM Compound: 5-fluorouracil	In vitro growth inhibition of L1210 cells 48 hours after administration of compound In vitro growth inhibition of L1210 cells 48 hours after administration of compound	[PMID: 7629806]
L1210	IC₅₀	0.22 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 4 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.22 μM Compound: 5-fluorouracil	In vitro growth inhibition of L1210 cells 24 hours after administration of compound In vitro growth inhibition of L1210 cells 24 hours after administration of compound	[PMID: 7629806]
L1210	IC₅₀	0.28 μM Compound: 5-Fluorouracil	Concentration required to inhibit 50% of cell growth on murine L1210 cells. Concentration required to inhibit 50% of cell growth on murine L1210 cells.	[PMID: 11052798]
L1210	IC₅₀	0.28 μM Compound: 5-Fluorouracil	Cytostatic activity against mouse L1210 cells Cytostatic activity against mouse L1210 cells	[PMID: 17931862]
L1210	IC₅₀	0.3 μM Compound: 5-FU	Effect on L1210/0 cells in culture Effect on L1210/0 cells in culture	[PMID: 2362278]
L1210	IC₅₀	0.32 μM Compound: 1, 5-FU	Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting Cytostatic activity against thymidine-kinase deficient mouse L1210 cells after 48 hrs by cell counting	[PMID: 21892829]
L1210	IC₅₀	0.32 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of cell growth of L1210 leukemic cell lines in mouse. Concentration required for 50% inhibition of cell growth of L1210 leukemic cell lines in mouse.	[PMID: 1992123]
L1210	IC₅₀	0.32 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of mouse leukemic L1210 cell lines. In vitro inhibitory effect on growth of mouse leukemic L1210 cell lines.	[PMID: 3373480]
L1210	IC₅₀	0.33 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting Cytostatic activity against mouse L1210 cells after 48 hrs by Coulter counting	[PMID: 25435471]
L1210	IC₅₀	0.33 μM Compound: 5-Fluorouracil	Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method Cytostatic activity against mouse L1210 cells assessed as inhibition of proliferation after 48 hrs by Coulter cell counting method	[PMID: 24906510]
L1210	IC₅₀	0.33 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse L1210 cells assessed as inhibition of cell proliferation Cytotoxicity against mouse L1210 cells assessed as inhibition of cell proliferation	[PMID: 26001344]
L1210	IC₅₀	0.33 μM Compound: 5-Fluorouracil	Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method Anti-proliferative activity against mouse L1210 cells measured after 48 hrs by coulter counter method	[PMID: 27750154]
L1210	IC₅₀	0.33 μM Compound: 5FU	Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay Cytotoxicity against mouse L1210 cells assessed as reduction in cell number after 48 hrs by cell counting assay	[PMID: 24631358]
L1210	IC₅₀	0.36 μg/mL Compound: 5-FU	Concentration at 50 percent inhibition of cell growth against mouse leukemia 1210 cell line in vitro Concentration at 50 percent inhibition of cell growth against mouse leukemia 1210 cell line in vitro	10.1016/S0960-894X(01)81041-6
L1210	IC₅₀	0.37 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.47 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells in presence of 500 uM uracil Cytostatic activity against mouse L1210 cells in presence of 500 uM uracil	[PMID: 21330014]
L1210	IC₅₀	0.49 μM Compound: 5-Fluorouracil	Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis Cytostatic activity against mouse L1210 cells after 2 days by coulter counter analysis	[PMID: 22405290]
L1210	IC₅₀	0.49 μM Compound: F-Uracil	Cytostatic activity against mouse L1210 cells Cytostatic activity against mouse L1210 cells	[PMID: 21917363]
L1210	IC₅₀	0.56 μM Compound: 5-FU	Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis Cytotoxicity against mouse L1210 cells after 2 days by coulter counter analysis	[PMID: 21232828]
L1210	IC₅₀	0.56 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis Cytostatic activity against mouse L1210 cells after 2 days by coulter counting analysis	[PMID: 21330014]
L1210	IC₅₀	0.6 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 4 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	0.62 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells in presence of 500 uM uridine Cytostatic activity against mouse L1210 cells in presence of 500 uM uridine	[PMID: 21330014]
L1210	IC₅₀	0.62 μM Compound: 5-Fluorouracil	In vitro cytotoxicity against murine Leukemia L1210 cells. In vitro cytotoxicity against murine Leukemia L1210 cells.	[PMID: 10229634]
L1210	IC₅₀	0.63 μM Compound: 5-fluorouracil	In vitro growth inhibition of L1210 cells 8 hours after administration of compound In vitro growth inhibition of L1210 cells 8 hours after administration of compound	[PMID: 7629806]
L1210	IC₅₀	0.69 μM Compound: 5-FU	Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay Antiproliferative activity against mouse L1210 cells after 2 days by MTT assay	[PMID: 18424155]
L1210	IC₅₀	0.97 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [6-3H]2'-deoxyuridine incorporation in to DNA by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	1.1 pM Compound: 5-FU	Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay Cytotoxicity against mouse L1210 cells after 72 hrs by MTT assay	[PMID: 21640594]
L1210	IC₅₀	1.3 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells in presence of 20 uM 2'-deoxyuridine Cytostatic activity against mouse L1210 cells in presence of 20 uM 2'-deoxyuridine	[PMID: 21330014]
L1210	IC₅₀	1010 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 8 h treatment Growth inhibition in L1210 mouse leukemia cells after 8 h treatment	[PMID: 11728193]
L1210	IC₅₀	125 nM Compound: 5-FU	Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 48 hr Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 48 hr	[PMID: 11063625]
L1210	IC₅₀	2.2 μM Compound: 5-fluorouracil	In vitro growth inhibition of L1210 cells 2 hours after administration of compound In vitro growth inhibition of L1210 cells 2 hours after administration of compound	[PMID: 7629806]
L1210	IC₅₀	200 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment Growth inhibition in L1210 mouse leukemia cells after 48 hr treatment	[PMID: 11728193]
L1210	IC₅₀	21 μM Compound: 5-FU	Cytostatic activity against mouse L1210 cells in presence of 20 uM thymidine Cytostatic activity against mouse L1210 cells in presence of 20 uM thymidine	[PMID: 21330014]
L1210	IC₅₀	220 nM Compound: 5-FU	Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 24 hr Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 24 hr	[PMID: 11063625]
L1210	IC₅₀	2200 nM Compound: 5-FU	Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 2 hr Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 2 hr	[PMID: 11063625]
L1210	IC₅₀	2500 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment Growth inhibition in L1210 mouse leukemia cells after 2 hr treatment	[PMID: 11728193]
L1210	IC₅₀	360 nM Compound: 5-FU	Growth inhibition in L1210 mouse leukemia cells after 24 h treatment Growth inhibition in L1210 mouse leukemia cells after 24 h treatment	[PMID: 11728193]
L1210	IC₅₀	4.9 μM Compound: 5-FU	Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA preincubated for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	51 μM Compound: 5-FU	Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA by liquid scintillation counting Inhibition of RNA synthesis in mouse L1210 cells assessed as [5-3H]uridine incorporation in to RNA by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	630 nM Compound: 5-FU	Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 8 hr Growth inhibition in L1210 mouse Leukemia cells for a treatment time of 8 hr	[PMID: 11063625]
L1210	IC₅₀	7 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxyuridine after preincubation for 15 mins by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	> 500 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	> 500 μM Compound: 5-FU	Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting Inhibition of DNA synthesis in mouse L1210 cells assessed as [methyl-3H]thymidine incorporation in to DNA preincubated for 24 hrs by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	>= 10 μM Compound: 5-FU	Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15 mins by liquid scintillation counting Inhibition of thymidylate synthase in mouse L1210 cells assessed as inhibition of tritium release from [5-3H]deoxycytidine after preincubation for 15 mins by liquid scintillation counting	[PMID: 21330014]
L1210	IC₅₀	1.0 x 10^-7 M Compound: FUra	Inhibition of cell growth of L1210 mouse Leukemia cells Inhibition of cell growth of L1210 mouse Leukemia cells	[PMID: 2967375]
L1210	IC₅₀	5.0 x 10^-7 M Compound: FUra	Concentration required for the 50% inhibition of growth of L1210 mouse leukemia cells in culture Concentration required for the 50% inhibition of growth of L1210 mouse leukemia cells in culture	[PMID: 7120290]
L1210/C	IC₅₀	0.2 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against mouse leukemia cell line L1210/c after 72 hr of incubation The compound was evaluated for antitumoral activity against mouse leukemia cell line L1210/c after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
L929	IC₅₀	1.38 μM Compound: 5-Fu	Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay Cytotoxicity against mouse L929 cells after 72 hrs by MTT assay	[PMID: 22687745]
L929	IC₅₀	2.98 μM Compound: 5-Fu	Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay Antiproliferative activity against mouse L929 cells after 48 hrs by CCK8 assay	[PMID: 26786698]
L929	IC₅₀	> 100 μM Compound: 5-Fu	Cytotoxicity against mouse L929 cells assessed as inhibition of cell proliferation by MTT assay Cytotoxicity against mouse L929 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
LFCl2A	IC₅₀	28.5 μM Compound: 5-fluoro uracil	In vitro cytotoxic activity against LFCl2A cell line derived from an hepatocarcinoma induced in the commentary rat by dimethylaminoazobenzene In vitro cytotoxic activity against LFCl2A cell line derived from an hepatocarcinoma induced in the commentary rat by dimethylaminoazobenzene	10.1016/S0960-894X(00)80263-2
LFCl2A	IC₅₀	28.5 μM Compound: 5-fluoro uracil	In vitro cytotoxicity against LFCl2A (rat hepatocarcinoma) cells. In vitro cytotoxicity against LFCl2A (rat hepatocarcinoma) cells.	10.1016/S0960-894X(01)81055-6
LNCaP	IC₅₀	0.03 μM Compound: 5-FU	Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay Cytotoxicity against human LNCAP cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay	[PMID: 27156770]
LNCaP	IC₅₀	4.9 μM Compound: 5-FU	Concentration required to inhibit proliferation of LNCaP prostate cancer cell lines Concentration required to inhibit proliferation of LNCaP prostate cancer cell lines	[PMID: 15341952]
LNCaP	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate LNCaP cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate LNCaP cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
LNCaP	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against prostate cancer LNCaP Cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer LNCaP Cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
LNCaP	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer LNCaP cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer LNCaP cell line by sulforhodamine B assay	[PMID: 16005217]
LNCaP	IC₅₀	47.18 μM Compound: F	Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human LNCAP cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
LNCaP	IC₅₀	5.21 μM Compound: 5-FU	Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay Antiproliferative activity against human LNCAP cells after 48 hrs by MTT assay	[PMID: 28666860]
LNCaP	IC₅₀	7.93 μM Compound: 5-Fu	Antiproliferative activity against human LNCaP cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antiproliferative activity against human LNCaP cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36931124]
LNCaP	IC₅₀	> 100 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against LNCaP cells Tested in vitro for anticancer activity against LNCaP cells	[PMID: 10072683]
LNCaP C4-2B	IC₅₀	38.2 μM Compound: 5-FU	Antiproliferative activity against human C4-2B cells after 48 hrs by MTT assay Antiproliferative activity against human C4-2B cells after 48 hrs by MTT assay	[PMID: 30108895]
LNCaP C4-2B	IC₅₀	5.64 μM Compound: 5-fluorouracil	Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay Antiproliferative activity against human C4-2B cells assessed as inhibition of cell viability after 48 hrs by MTT reduction assay	[PMID: 27295506]
LOX IMVI	GI₅₀	0.24 μM Compound: 5-FU	Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay Growth inhibition of human LOXIMVI cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
LS-1034	IC₅₀	0.11 μM Compound: 5-FU	Inhibition of human LS1034 cell spheroids incubated for 7 days by luciferase based assay Inhibition of human LS1034 cell spheroids incubated for 7 days by luciferase based assay	[PMID: 36780832]
LS-513	IC₅₀	84 μM Compound: 5-FU	Cytotoxicity against human LS-513 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay Cytotoxicity against human LS-513 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay	[PMID: 38536967]
LS180	IC₅₀	3.4 μM Compound: 5-Fu	Cytotoxicity against human LS180 cells assessed as cell inhibition measured after 72 hrs by MTT assay Cytotoxicity against human LS180 cells assessed as cell inhibition measured after 72 hrs by MTT assay	[PMID: 36774698]
LS180	IC₅₀	38.92 μM Compound: FUra	Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against human LS180 cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
LX-2	IC₅₀	0.178 μM Compound: 5-FU	Antiproliferative activity against human LX2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay Antiproliferative activity against human LX2 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay	[PMID: 38626522]
Leukemia cell	GI₅₀	1.51 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by SRB assay Cytotoxicity against human leukemia cells after 48 hrs by SRB assay	[PMID: 23994328]
Leukemia cell	GI₅₀	15.09 μM Compound: 5-FU	Growth inhibition of human leukemia cells after 48 hrs Growth inhibition of human leukemia cells after 48 hrs	[PMID: 18950904]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by coulter counting Cytotoxicity against human leukemia cells after 48 hrs by coulter counting	[PMID: 22056277]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Growth inhibition of human leukemia cells after 48 hrs by coulter counter method Growth inhibition of human leukemia cells after 48 hrs by coulter counter method	[PMID: 22119151]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human leukemia cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis Cytotoxicity against human leukemia cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Cytotoxicity against human leukemia cells at 10 uM after 48 hrs Cytotoxicity against human leukemia cells at 10 uM after 48 hrs	[PMID: 24469112]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-FU	Growth inhibition of human leukemia cells after 48 hrs by SRB assay Growth inhibition of human leukemia cells after 48 hrs by SRB assay	[PMID: 27554444]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-fu	Antitumor activity against human leukemia cells after 48 hrs by SRB assay Antitumor activity against human leukemia cells after 48 hrs by SRB assay	[PMID: 20350811]
Leukemia cell	GI₅₀	15.1 μM Compound: 5-fu	Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis Antiproliferative activity against human leukemia cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Leukemia cell	GI₅₀	52.5 μM Compound: 5-fluorouracil	Cytotoxicity against human leukemia cells Cytotoxicity against human leukemia cells	[PMID: 17562365]
LoVo	IC₅₀	11.5 μM Compound: 5-FU	Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay Growth inhibition of human LoVo cells after 48 hrs by CCK-8 assay	[PMID: 30106289]
LoVo	IC₅₀	12.6 μM Compound: 5-FU	Anticancer activity against human LoVo cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human LoVo cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
LoVo	IC₅₀	12.7 μM Compound: 5-Fu	Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human LoVo cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
LoVo	IC₅₀	2.7 μM Compound: 5-FU	Antiproliferative activity against human LoVo cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human LoVo cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
LoVo	IC₅₀	3.3 μM Compound: 5-Fu	Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay Antiproliferative activity against human LoVo cells after 48 hrs by MTT assay	[PMID: 22840493]
LoVo	IC₅₀	4.69 μM Compound: FUra	Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method Antiproliferative activity against human LoVo cells assessed as growth inhibition after 72 hrs by SRB method	[PMID: 25644674]
LoVo	IC₅₀	8.35 μM Compound: 5-FU	Antitumor activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human LoVo cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
LoVo	IC₅₀	9.89 μM Compound: 5-Fu	Cytotoxicity against human LoVo cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human LoVo cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
M-HeLa	IC₅₀	62 μM Compound: 5-Fluorouracil	Cytotoxicity against human HelaM cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human HelaM cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
M14	GI₅₀	0.7 μg/mL Compound: 5FU	Cytotoxicity against human M14 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human M14 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
M14	GI₅₀	0.98 μM Compound: 5-FU	Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human M14 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
M14	GI₅₀	0.98 μM Compound: 5-FU	Anticancer activity against human M14 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human M14 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
M14	GI₅₀	22.4 μM Compound: 5FU	Cytotoxicity against human M14 cells after 48 hrs Cytotoxicity against human M14 cells after 48 hrs	[PMID: 18798609]
M14	GI₅₀	32.4 μM Compound: 5FU	Cytotoxicity against human M14 cells Cytotoxicity against human M14 cells	[PMID: 20356752]
M14	IC₅₀	0.98 μM Compound: 5-Fluorouracil	Cytotoxicity against human M14 cells assessed as cell growth inhibition Cytotoxicity against human M14 cells assessed as cell growth inhibition	[PMID: 36470105]
MCF-10A	IC₅₀	0.73 μM Compound: 5-FU	Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay Cytotoxicity against human MCF10A cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
MCF-10A	IC₅₀	17.2 μM Compound: 5-FU	Antiproliferation activity against human MCF-10A cells assessed as reduction in cell viability under hypoxic conditions by MTT assay Antiproliferation activity against human MCF-10A cells assessed as reduction in cell viability under hypoxic conditions by MTT assay	[PMID: 33965860]
MCF-10A	IC₅₀	19.5 μM Compound: 5-Fu	Antiproliferative activity against human MCF-10A cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human MCF-10A cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 38897138]
MCF-10A	IC₅₀	39.7 μM Compound: 5-FU	Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33166925]
MCF-10A	IC₅₀	5.09 μM Compound: 5-Fu	Antiproliferative activity against human MCF-10A cells incubated for 72 hrs by SRB assay Antiproliferative activity against human MCF-10A cells incubated for 72 hrs by SRB assay	[PMID: 39054645]
MCF-10A	IC₅₀	8.06 μM Compound: 5-Fu	Cytotoxicity against human MCF10A cells after 3 days by SRB assay Cytotoxicity against human MCF10A cells after 3 days by SRB assay	[PMID: 24704691]
MCF-10A	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human MCF10A cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
MCF-10A	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MCF-10A cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MCF7	CC₅₀	5 μM Compound: 5-Fu	Tumor selectivity index, ratio of CC50 for human H4 cells to CC50 for human MCF7 cells Tumor selectivity index, ratio of CC50 for human H4 cells to CC50 for human MCF7 cells	[PMID: 18037195]
MCF7	CC₅₀	768.8 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 17337193]
MCF7	CC₅₀	768.8 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 18037195]
MCF7	CC₅₀	768.8 μM Compound: 5FU	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 17548129]
MCF7	ED₅₀	0.2 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 16309328]
MCF7	GI₅₀	0.07 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MCF7	GI₅₀	0.07 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MCF7	GI₅₀	0.3 μg/mL Compound: 5FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
MCF7	GI₅₀	1.67 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 28400235]
MCF7	GI₅₀	14.5 nM Compound: 5FU	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 23094992]
MCF7	GI₅₀	15 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19572613]
MCF7	GI₅₀	2.8 μM Compound: 5FU	Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MCF7 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
MCF7	GI₅₀	3.6 μM Compound: 5-FU	Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay Growth inhibition of human MCF7 cells measured after 72 hrs by MTT assay	[PMID: 27504537]
MCF7	GI₅₀	4.5 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 27688184]
MCF7	GI₅₀	4.5 μM Compound: 5FU	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 20356752]
MCF7	GI₅₀	6.5 μM Compound: 5FU	Cytotoxicity against human MCF7 cells after 48 hrs Cytotoxicity against human MCF7 cells after 48 hrs	[PMID: 18798609]
MCF7	GI₅₀	8.3 μM Compound: 5-fluorouracil	Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human MCF7 cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
MCF7	GI₅₀	8.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
MCF7	GI₅₀	9.9 μM Compound: 5-Fu	Growth inhibition of human MCF7 cells after 48 hrs by SRB assay Growth inhibition of human MCF7 cells after 48 hrs by SRB assay	[PMID: 22512908]
MCF7	GI₅₀	> 10 μM Compound: 5-Fu	Growth inhibition of human MCF7 cells after 72 hrs by Alamar Blue assay Growth inhibition of human MCF7 cells after 72 hrs by Alamar Blue assay	[PMID: 19406645]
MCF7	IC₅₀	0.0052 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as growth inhibition after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as growth inhibition after 72 hr by MTT assay	10.1007/s00044-012-0181-0
MCF7	IC₅₀	0.02 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
MCF7	IC₅₀	0.0415 mM Compound: 5-Fluorouracil	Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human MCF7 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
MCF7	IC₅₀	0.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition Cytotoxicity against human MCF7 cells assessed as cell growth inhibition	[PMID: 36470105]
MCF7	IC₅₀	0.09 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 26617970]
MCF7	IC₅₀	0.12 x 10^-2 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 16038565]
MCF7	IC₅₀	0.235 μM Compound: 5-FU	Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay	[PMID: 36921275]
MCF7	IC₅₀	0.3 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs Antiproliferative activity against human MCF7 cells after 72 hrs	[PMID: 17548198]
MCF7	IC₅₀	0.3 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 19743863]
MCF7	IC₅₀	0.59 μM Compound: 5-FU	Antiproliferative activity against human MCF-7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay Antiproliferative activity against human MCF-7 cells assessed as cell growth inhibition measured after 72 hrs by SRB assay	[PMID: 32485532]
MCF7	IC₅₀	0.67 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22154835]
MCF7	IC₅₀	0.67 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay Cytotoxicity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 19932530]
MCF7	IC₅₀	0.69 mg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 3 days MTT assay Cytotoxicity against human MCF7 cells after 3 days MTT assay	[PMID: 22796042]
MCF7	IC₅₀	0.9 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human MCF7 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
MCF7	IC₅₀	1.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 24060486]
MCF7	IC₅₀	1.25 μM Compound: 5-Florouracil	Anticancer activity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay Anticancer activity against Homo sapiens (human) MCF7 cells assessed as inhibition of cell proliferation after 24 hr by MTT assay	10.1007/s00044-012-0260-2
MCF7	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 24835633]
MCF7	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by SRB assay	[PMID: 28219046]
MCF7	IC₅₀	1.4 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 30108969]
MCF7	IC₅₀	1.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT microassay Cytotoxicity against human MCF7 cells by MTT microassay	[PMID: 17320246]
MCF7	IC₅₀	1.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 18606546]
MCF7	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition by MTT assay	[PMID: 34000484]
MCF7	IC₅₀	1.75 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 28165738]
MCF7	IC₅₀	1.8 μM Compound: 5-Fluoro uracilc	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 24 hrs by MTT assay	[PMID: 24641975]
MCF7	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells by MTT assay Antiproliferative activity against human MCF7 cells by MTT assay	[PMID: 29798826]
MCF7	IC₅₀	1.9 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 27528432]
MCF7	IC₅₀	10 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 37859725]
MCF7	IC₅₀	10.14 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23685571]
MCF7	IC₅₀	10.2 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
MCF7	IC₅₀	10.4 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
MCF7	IC₅₀	10.6 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
MCF7	IC₅₀	10.8 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27262600]
MCF7	IC₅₀	10.92 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
MCF7	IC₅₀	11 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 39106494]
MCF7	IC₅₀	11.1 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis Cytotoxicity against human MCF7 cells assessed as cell survivability after 24 hrs by crystal violet staining based microscopic analysis	[PMID: 27234893]
MCF7	IC₅₀	11.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 27189676]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23558238]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Growth inhibition against human MCF7 cells after 48 hrs by MTT assay Growth inhibition against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23999046]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 2 days by MTT assay Cytotoxicity against human MCF7 cells after 2 days by MTT assay	[PMID: 24767839]
MCF7	IC₅₀	11.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay Cytotoxicity against human MCF7 cells assessed as induction of cell death incubated for 2 days by MTT assay	[PMID: 26259802]
MCF7	IC₅₀	11.62 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 39016216]
MCF7	IC₅₀	12.1 μg/mL Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 25017036]
MCF7	IC₅₀	12.23 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells measured after 72 hrs by MTT assay	[PMID: 37379957]
MCF7	IC₅₀	12.24 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 25707012]
MCF7	IC₅₀	12.3 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
MCF7	IC₅₀	12.5 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22727445]
MCF7	IC₅₀	12.5 μM Compound: 5-FU	Antiproliferation activity against human MCF7 cells assessed as reduction in cell viability under hypoxic conditions by MTT assay Antiproliferation activity against human MCF7 cells assessed as reduction in cell viability under hypoxic conditions by MTT assay	[PMID: 33965860]
MCF7	IC₅₀	12.6 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
MCF7	IC₅₀	13.16 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
MCF7	IC₅₀	13.19 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
MCF7	IC₅₀	13.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	10.1039/C5MD00240K
MCF7	IC₅₀	13.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27133593]
MCF7	IC₅₀	136.5 μM Compound: 5-FU	Cytotoxicity in human MCF-7 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human MCF-7 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
MCF7	IC₅₀	14 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22130132]
MCF7	IC₅₀	14.1 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 21109433]
MCF7	IC₅₀	14.2 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22749192]
MCF7	IC₅₀	14.26 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation by CCK8 assay	[PMID: 25442303]
MCF7	IC₅₀	14.7 μM Compound: 5-Fu	Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 28987604]
MCF7	IC₅₀	15 μM Compound: 5 Fluorouracil	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
MCF7	IC₅₀	15 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 72 hrs by MTT assay Growth inhibition of human MCF7 cells after 72 hrs by MTT assay	[PMID: 18640746]
MCF7	IC₅₀	15 μM Compound: 5-FU	Antitumor activity against human MCF7 cells after 24 hrs by MTT assay Antitumor activity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 20211564]
MCF7	IC₅₀	15 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test Antiproliferative activity against human MCF7 cells after 48 hrs by resazurin reduction test	[PMID: 21530016]
MCF7	IC₅₀	15 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19795843]
MCF7	IC₅₀	15 μM Compound: 5-Fluorouracil	Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay Cytostatic activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22405290]
MCF7	IC₅₀	15 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19618920]
MCF7	IC₅₀	15 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 19919065]
MCF7	IC₅₀	15.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
MCF7	IC₅₀	15.14 μM Compound: 5-Fu	Antitumor activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36931124]
MCF7	IC₅₀	15.2 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human MCF7 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
MCF7	IC₅₀	15.2 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 3 days by MTT assay Cytotoxicity against human MCF7 cells after 3 days by MTT assay	[PMID: 21144621]
MCF7	IC₅₀	15.22 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 38107169]
MCF7	IC₅₀	15.78 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 29486954]
MCF7	IC₅₀	16.2 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 22840493]
MCF7	IC₅₀	16.27 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells measured after 48 hrs by MTT assay	[PMID: 32135407]
MCF7	IC₅₀	16.28 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 30981113]
MCF7	IC₅₀	16.3 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
MCF7	IC₅₀	16.32 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by SRB assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth by SRB assay	[PMID: 35594653]
MCF7	IC₅₀	16.7 μM Compound: 5-FU	Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
MCF7	IC₅₀	16.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23490159]
MCF7	IC₅₀	166 μM Compound: 5-FLU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 34606997]
MCF7	IC₅₀	17.11 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
MCF7	IC₅₀	17.2 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23279864]
MCF7	IC₅₀	178 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 29207336]
MCF7	IC₅₀	18.13 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability by MTT assay	[PMID: 34157389]
MCF7	IC₅₀	18.58 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
MCF7	IC₅₀	18.75 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29475156]
MCF7	IC₅₀	19.2 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28073676]
MCF7	IC₅₀	19.39 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26363869]
MCF7	IC₅₀	2 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26854375]
MCF7	IC₅₀	2.13 μM Compound: 5-Fluorouracil	Cytotoxicity activity against human MCF7 cells incubated for 48 hrs by SRB assay Cytotoxicity activity against human MCF7 cells incubated for 48 hrs by SRB assay	[PMID: 34119830]
MCF7	IC₅₀	2.19 μg/mL Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29100732]
MCF7	IC₅₀	2.2 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells measured after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells measured after 24 hrs by MTT assay	[PMID: 34875389]
MCF7	IC₅₀	2.2 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 22011319]
MCF7	IC₅₀	2.35 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29223098]
MCF7	IC₅₀	2.36 μM Compound: 5-Fluorouracil	Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 26231080]
MCF7	IC₅₀	2.3 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against human MCF7 cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
MCF7	IC₅₀	2.3 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 22204901]
MCF7	IC₅₀	2.3 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
MCF7	IC₅₀	2.46 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay	[PMID: 34847409]
MCF7	IC₅₀	2.5 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay Cytotoxicity against human MCF7 cells after 96 hrs by MTT assay	[PMID: 23022735]
MCF7	IC₅₀	2.86 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 3 days by SRB assay Cytotoxicity against human MCF7 cells after 3 days by SRB assay	[PMID: 24704691]
MCF7	IC₅₀	2.9 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) MCF7 cells by SRB assay Cytotoxicity against Homo sapiens (human) MCF7 cells by SRB assay	10.1007/s00044-010-9500-5
MCF7	IC₅₀	20.09 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay	[PMID: 33894490]
MCF7	IC₅₀	21.06 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth	[PMID: 36089111]
MCF7	IC₅₀	21.11 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
MCF7	IC₅₀	21.47 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
MCF7	IC₅₀	22.439 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34000485]
MCF7	IC₅₀	22.6 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30527868]
MCF7	IC₅₀	22.8 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 34883453]
MCF7	IC₅₀	222.6 μM Compound: 5-Fuorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27017265]
MCF7	IC₅₀	23.9 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38677112]
MCF7	IC₅₀	24.5 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 37098306]
MCF7	IC₅₀	24.58 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 22801644]
MCF7	IC₅₀	24.78 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 37343499]
MCF7	IC₅₀	25.44 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 37859725]
MCF7	IC₅₀	26.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell viability after 72 hrs by MTT assay	[PMID: 26922223]
MCF7	IC₅₀	26.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28110871]
MCF7	IC₅₀	26.14 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30142612]
MCF7	IC₅₀	26.34 μM Compound: 5-FU	Cytotoxicity against human MCF7 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
MCF7	IC₅₀	26.57 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30677614]
MCF7	IC₅₀	26.65 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31877536]
MCF7	IC₅₀	26.65 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
MCF7	IC₅₀	26.67 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human MCF7 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
MCF7	IC₅₀	26.9 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells after 48 hrs by MTT assay Anticancer activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 25462264]
MCF7	IC₅₀	26.91 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29635169]
MCF7	IC₅₀	27.89 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 30243153]
MCF7	IC₅₀	28.73 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 28458133]
MCF7	IC₅₀	28.97 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 29174813]
MCF7	IC₅₀	29.4 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30108895]
MCF7	IC₅₀	29.41 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
MCF7	IC₅₀	29.5 μM Compound: 5-FU	Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay Anticancer activity against human MCF7 cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
MCF7	IC₅₀	3 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27343853]
MCF7	IC₅₀	3 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay Antiproliferative activity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 29326016]
MCF7	IC₅₀	3.15 μM Compound: 5-fluorouracil	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 32311607]
MCF7	IC₅₀	3.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28666860]
MCF7	IC₅₀	3.2 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell growth incubated for 72 hrs by MTT assay	[PMID: 31471102]
MCF7	IC₅₀	3.5 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay	[PMID: 38107180]
MCF7	IC₅₀	3.5 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition incubated for 72 hrs by SRB assay	[PMID: 38688437]
MCF7	IC₅₀	3.5 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 24332497]
MCF7	IC₅₀	3.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 22409771]
MCF7	IC₅₀	3.5 μM Compound: 5FU	Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MCF7 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
MCF7	IC₅₀	3.52 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 24835817]
MCF7	IC₅₀	3.6 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23792763]
MCF7	IC₅₀	30 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells by MTT assay Cytotoxicity against human MCF7 cells by MTT assay	[PMID: 28371676]
MCF7	IC₅₀	30.41 μM Compound: Fluorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27128180]
MCF7	IC₅₀	30 μg/mL Compound: 5-FU	Anticancer activity against human MCF7 cells Anticancer activity against human MCF7 cells	[PMID: 32795767]
MCF7	IC₅₀	30 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells by MTT assay Antiproliferative activity against human MCF7 cells by MTT assay	[PMID: 31546197]
MCF7	IC₅₀	31 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 22283451]
MCF7	IC₅₀	31 μM Compound: Fluorouracil	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 21774474]
MCF7	IC₅₀	31.04 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells overexpressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay Anticancer activity against human MCF7 cells overexpressing PDK assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31509699]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23665106]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 26703795]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTS assay	[PMID: 27575478]
MCF7	IC₅₀	32.18 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
MCF7	IC₅₀	32.18 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
MCF7	IC₅₀	32.27 μM Compound: F	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
MCF7	IC₅₀	32.626 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 29223717]
MCF7	IC₅₀	34.48 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay	[PMID: 25466196]
MCF7	IC₅₀	34 μg/mL Compound: 5-FU	Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay Cytotoxicity against human MCF7 cells after 36 hrs by MTT assay	[PMID: 20961091]
MCF7	IC₅₀	35 μM Compound: 5-fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 22304344]
MCF7	IC₅₀	35.32 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by Alamar blue dye based assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 48 hrs by Alamar blue dye based assay	[PMID: 38171252]
MCF7	IC₅₀	38.5 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 28756264]
MCF7	IC₅₀	39.88 μM Compound: Fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 25016234]
MCF7	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 19560842]
MCF7	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Antiproliferative activity in human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity in human MCF7 cells after 72 hrs by MTT assay	10.1039/C6MD00252H
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 3 days by SRB assay Antiproliferative activity against human MCF7 cells after 3 days by SRB assay	[PMID: 18069093]
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells Antiproliferative activity against human MCF7 cells	[PMID: 18194866]
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay Cytotoxicity against human MCF7 cells expressing wild type p53 and ras mutant after 3 days by SRB assay	[PMID: 21126804]
MCF7	IC₅₀	4.32 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay Cytotoxicity against human MCF7 cells after 6 days by SRB colorimetric assay	[PMID: 21684047]
MCF7	IC₅₀	4.42 μM Compound: 5-FU	Antitumor activity against human MCF7 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human MCF7 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
MCF7	IC₅₀	4.5 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 3 days by MTT assay Antiproliferative activity against human MCF7 cells after 3 days by MTT assay	[PMID: 18424155]
MCF7	IC₅₀	4.55 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
MCF7	IC₅₀	4.6 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
MCF7	IC₅₀	4.7 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 144 hrs by crystal violet staining method	[PMID: 22450132]
MCF7	IC₅₀	4.7 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method Antiproliferative activity against human MCF7 cells after 72 hrs by crystal violet staining method	[PMID: 22765897]
MCF7	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining Cytotoxicity against human MCF7 cells after 72 hrs by crystal violet staining	[PMID: 22959205]
MCF7	IC₅₀	4.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 after 72 hrs by MTT assay Cytotoxicity against human MCF7 after 72 hrs by MTT assay	[PMID: 19233650]
MCF7	IC₅₀	4.76 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
MCF7	IC₅₀	4.8 μM Compound: 5-fluorouracil	Antiproliferative activity in MCF-7 human breast cancer cells Antiproliferative activity in MCF-7 human breast cancer cells	[PMID: 15658875]
MCF7	IC₅₀	4.8 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 72 hrs Cytotoxicity against human MCF7 cells after 72 hrs	[PMID: 17336074]
MCF7	IC₅₀	4.8 μg/mL Compound: 5-flourouracil	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27597407]
MCF7	IC₅₀	41 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against MCF-7 cells Tested in vitro for anticancer activity against MCF-7 cells	[PMID: 10072683]
MCF7	IC₅₀	41.51 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells after 24 hrs by MTT assay	[PMID: 31401008]
MCF7	IC₅₀	42.01 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21524829]
MCF7	IC₅₀	42.78 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26883148]
MCF7	IC₅₀	42.78 μM Compound: 5FU	Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human MCF7 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
MCF7	IC₅₀	45.04 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as cell growth inhibition by MTT assay Anticancer activity against human MCF7 cells assessed as cell growth inhibition by MTT assay	[PMID: 36481599]
MCF7	IC₅₀	45.04 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 36481599]
MCF7	IC₅₀	48.45 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition Cytotoxicity against human MCF7 cells assessed as cell growth inhibition	[PMID: 35809817]
MCF7	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23800391]
MCF7	IC₅₀	5.012 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 26301558]
MCF7	IC₅₀	5.05 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
MCF7	IC₅₀	5.167 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT reagent based ELISA Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT reagent based ELISA	[PMID: 37556946]
MCF7	IC₅₀	5.2 x 10^-7 M Compound: 5-FU	Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay Cytotoxicity against human MCF7 cells after 72 hrs by CCK8 assay	[PMID: 26725029]
MCF7	IC₅₀	5.2 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
MCF7	IC₅₀	5.32 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
MCF7	IC₅₀	5.4 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31276896]
MCF7	IC₅₀	5.4 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35694689]
MCF7	IC₅₀	5.44 μM Compound: 5-Fu	Antiproliferation activity against human MCF-7 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human MCF-7 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
MCF7	IC₅₀	5.5 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 31926469]
MCF7	IC₅₀	5.5 μg/mL Compound: 5-Fu	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 31761383]
MCF7	IC₅₀	5.6 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
MCF7	IC₅₀	5.7 μM Compound: 5-Fluorouracil	Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Antitumor activity against human MCF7 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
MCF7	IC₅₀	5.8 μM Compound: 5-FU	Cytotoxicity against ERalpha-dependent human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against ERalpha-dependent human MCF7 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33166925]
MCF7	IC₅₀	52.07 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
MCF7	IC₅₀	57 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 31057737]
MCF7	IC₅₀	57.09 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 30108924]
MCF7	IC₅₀	6.11 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 29254641]
MCF7	IC₅₀	6.51 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth incubated for 48 hrs by CellTiter 96 Aqueous One Solution Cell Proliferation Assay	[PMID: 38626522]
MCF7	IC₅₀	6.53 μM Compound: FUra	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 23867603]
MCF7	IC₅₀	6.53 μM Compound: FUra	Cytotoxicity against human MCF7cells after 72 hrs by SRB assay Cytotoxicity against human MCF7cells after 72 hrs by SRB assay	[PMID: 27073055]
MCF7	IC₅₀	6.53 μM Compound: FUra	Cytotoxicity against human MCF7 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against human MCF7 cells assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
MCF7	IC₅₀	63 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 72 hrs by MTT assay	[PMID: 29908443]
MCF7	IC₅₀	64 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human MCF7 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
MCF7	IC₅₀	66.91 μM Compound: 5-Fluoruracil	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22555152]
MCF7	IC₅₀	7.08 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 24819956]
MCF7	IC₅₀	7.12 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 27987485]
MCF7	IC₅₀	7.12 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells after 72 hrs by MTT assay Anticancer activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 25001482]
MCF7	IC₅₀	7.21 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 28759876]
MCF7	IC₅₀	7.33 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23644193]
MCF7	IC₅₀	7.42 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
MCF7	IC₅₀	7.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31546197]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Antitumor activity against human MCF7 cells after 72 hrs by MTT assay Antitumor activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 21486694]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 23353743]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 23792764]
MCF7	IC₅₀	7.54 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
MCF7	IC₅₀	7.61 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
MCF7	IC₅₀	7.67 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
MCF7	IC₅₀	7.76 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 24798098]
MCF7	IC₅₀	7.8 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay Antiproliferative activity against human MCF7 cells after 3 days by sulforhodamine B assay	[PMID: 30248657]
MCF7	IC₅₀	7.9 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 28431341]
MCF7	IC₅₀	71.49 μM Compound: 2; 5-FU	Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 27322756]
MCF7	IC₅₀	78.28 μM Compound: 5-FU	Growth inhibition of human MCF7 cells after 48 hrs by WST1 assay Growth inhibition of human MCF7 cells after 48 hrs by WST1 assay	[PMID: 28126436]
MCF7	IC₅₀	78.28 μM Compound: 5-FU	Anticancer activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay Anticancer activity against human MCF7 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay	[PMID: 36481599]
MCF7	IC₅₀	78.28 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth	[PMID: 36543034]
MCF7	IC₅₀	78.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells by MTT reduction assay Antiproliferative activity against human MCF7 cells by MTT reduction assay	[PMID: 33421712]
MCF7	IC₅₀	78.6 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 23067549]
MCF7	IC₅₀	79.3 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	10.1039/C6MD00234J
MCF7	IC₅₀	8.41 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 35609396]
MCF7	IC₅₀	8.5 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
MCF7	IC₅₀	8.77 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
MCF7	IC₅₀	8.93 μM Compound: 5-Fu	Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25180925]
MCF7	IC₅₀	9.12 μM Compound: 5-Fu	Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Anticancer activity against human MCF7 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25655718]
MCF7	IC₅₀	9.25 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 27771599]
MCF7	IC₅₀	9.49 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
MCF7	IC₅₀	9.56 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against human MCF7 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
MCF7	IC₅₀	9.6 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs Cytotoxicity against human MCF7 cells assessed as growth inhibition after 72 hrs	[PMID: 21295381]
MCF7	IC₅₀	9.67 μM Compound: 5-FU	Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay	[PMID: 22079378]
MCF7	IC₅₀	9.74 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 31200236]
MCF7	IC₅₀	9.79 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 24286761]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Antitumor activity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay Antitumor activity against human MCF7 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 23313635]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay Cytotoxicity against human MCF7 cells assessed as increase in growth inhibition by measuring decrease in cell viability incubated for 72 hrs and measured after 2 hrs by microplate reader based WST-1 assay	[PMID: 31416740]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against drug-resistant TCCD-induced human MCF7 cells overexpressing CYP1B1 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against drug-resistant TCCD-induced human MCF7 cells overexpressing CYP1B1 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31803401]
MCF7	IC₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31803401]
MCF7	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay	[PMID: 22537362]
MCF7	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MCF7	IC₅₀	> 200 μM Compound: 5-FLU	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 34606997]
MCF7	IC₅₀	> 40 μM Compound: 5-fluorouracil	Anticancer activity against human MCF7 cells Anticancer activity against human MCF7 cells	[PMID: 31945642]
MCF7	IC₅₀	> 50 μM Compound: 5-Fu	Antiproliferative activity against human MCF7 cells by CCK8 assay Antiproliferative activity against human MCF7 cells by CCK8 assay	[PMID: 37939862]
MDA-MB-231	GI₅₀	54 μM Compound: 5-fluorouracil	Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human MDA-MB-231 cells after 48 hrs by SRB assay	[PMID: 20438092]
MDA-MB-231	GI₅₀	6.6 μM Compound: 5-FU	Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MDA-MB-231 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MDA-MB-231	GI₅₀	6.6 μM Compound: 5-FU	Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MDA-MB-231	IC₅₀	1.1 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
MDA-MB-231	IC₅₀	1.58 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 37360398]
MDA-MB-231	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
MDA-MB-231	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay	[PMID: 27561719]
MDA-MB-231	IC₅₀	1.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
MDA-MB-231	IC₅₀	10.22 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MDA-MB-231	IC₅₀	13 μM Compound: 5-FU	Anticancer activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Anticancer activity against human MDA-MB-231 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 33940466]
MDA-MB-231	IC₅₀	13.65 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells by after 48 hrs by MTT assay	[PMID: 22579780]
MDA-MB-231	IC₅₀	13.65 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 23920246]
MDA-MB-231	IC₅₀	13.86 μM Compound: 5Fu	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 37837671]
MDA-MB-231	IC₅₀	15 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay	[PMID: 34516133]
MDA-MB-231	IC₅₀	15.74 μM Compound: 5-FU	Cytotoxicity against Non-ERalpha-dependent human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against Non-ERalpha-dependent human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33166925]
MDA-MB-231	IC₅₀	16.117 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition measured after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition measured after 72 hrs by MTT assay	[PMID: 34000485]
MDA-MB-231	IC₅₀	16.37 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells incubated for 72 hrs by SRB assay	[PMID: 39054645]
MDA-MB-231	IC₅₀	17.74 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
MDA-MB-231	IC₅₀	18.12 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay Cytotoxicity against human MDA-MB-231 cells after 3 days by SRB assay	[PMID: 24704691]
MDA-MB-231	IC₅₀	19 μM Compound: 5 Fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
MDA-MB-231	IC₅₀	2.45 μM Compound: FU	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 24941129]
MDA-MB-231	IC₅₀	2.72 μM Compound: 5-Fluorouracil	Cytotoxicity against Homo sapiens (human) MDA231 cells assessed as inhibition of cell growth after 48 hr by MTT assay Cytotoxicity against Homo sapiens (human) MDA231 cells assessed as inhibition of cell growth after 48 hr by MTT assay	10.1007/s00044-012-0209-5
MDA-MB-231	IC₅₀	20 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
MDA-MB-231	IC₅₀	21.05 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 30318440]
MDA-MB-231	IC₅₀	21.838 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells by MTT assay Cytotoxicity against human MDA-MB-231 cells by MTT assay	[PMID: 36335743]
MDA-MB-231	IC₅₀	22.53 μM Compound: 2; 5-FU	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 27322756]
MDA-MB-231	IC₅₀	24.5 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
MDA-MB-231	IC₅₀	24.6 μM Compound: Fluorouracil	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 25016234]
MDA-MB-231	IC₅₀	24.6 μM Compound: Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 27128180]
MDA-MB-231	IC₅₀	25 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	[PMID: 34171512]
MDA-MB-231	IC₅₀	25.31 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 72 hrs by MTT assay	[PMID: 33894490]
MDA-MB-231	IC₅₀	26.73 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35797901]
MDA-MB-231	IC₅₀	29.38 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition measured after 48 hrs by WST-1 assay	[PMID: 33129590]
MDA-MB-231	IC₅₀	3.5 μM Compound: 5-FU	Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human MDA231 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
MDA-MB-231	IC₅₀	3.5 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay	[PMID: 34847409]
MDA-MB-231	IC₅₀	31.57 μM Compound: 5-Fu	Cytotoxicity against human MDA231 cells by MTT assay Cytotoxicity against human MDA231 cells by MTT assay	[PMID: 22801644]
MDA-MB-231	IC₅₀	35.91 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
MDA-MB-231	IC₅₀	35.91 μM Compound: 5-FU	Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human MDA-MB-231 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 29657100]
MDA-MB-231	IC₅₀	35.98 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
MDA-MB-231	IC₅₀	4.33 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 28431881]
MDA-MB-231	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs	[PMID: 21295381]
MDA-MB-231	IC₅₀	4.75 μM Compound: 5-fluoro uracil	Cytotoxicity against human MDA-MB-231 cells incubated for 3 days by MTT assay Cytotoxicity against human MDA-MB-231 cells incubated for 3 days by MTT assay	[PMID: 33152379]
MDA-MB-231	IC₅₀	45.43 μM Compound: 5-FU	Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay Anticancer activity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 26413726]
MDA-MB-231	IC₅₀	45.43 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 27397498]
MDA-MB-231	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTT assay	[PMID: 27987485]
MDA-MB-231	IC₅₀	5.2 μM Compound: 5-FU	Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by WST-8 assay	[PMID: 27311895]
MDA-MB-231	IC₅₀	5.2 μM Compound: 5-fluorouracil	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by WST8 assay	[PMID: 25919052]
MDA-MB-231	IC₅₀	5.82 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 25870131]
MDA-MB-231	IC₅₀	5.85 μM Compound: 5-Fu	Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay Antiproliferation activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by CCK8 assay	[PMID: 34186178]
MDA-MB-231	IC₅₀	53.47 μM Compound: Fluorouracil	Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells after 48 hrs by MTT assay	[PMID: 28789892]
MDA-MB-231	IC₅₀	59 μM Compound: Fluorouracil	Cytotoxicity against human MDA-MB-231 cells Cytotoxicity against human MDA-MB-231 cells	[PMID: 21774474]
MDA-MB-231	IC₅₀	6.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition	[PMID: 36470105]
MDA-MB-231	IC₅₀	6.81 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 48 hrs by Alamar blue dye based assay Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth measured after 48 hrs by Alamar blue dye based assay	[PMID: 38171252]
MDA-MB-231	IC₅₀	62 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells Cytotoxicity against human MDA-MB-231 cells	[PMID: 22283451]
MDA-MB-231	IC₅₀	66.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 24 hrs Antiproliferative activity against human MDA-MB-231 cells assessed as cell viability after 24 hrs	[PMID: 33139111]
MDA-MB-231	IC₅₀	67.5 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-231 cells assessed as cell inhibition measured after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell inhibition measured after 72 hrs by MTT assay	[PMID: 36774698]
MDA-MB-231	IC₅₀	7.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31546197]
MDA-MB-231	IC₅₀	7.75 μM Compound: 5-FU	Antitumor activity against human MDA-MB-231 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay Antitumor activity against human MDA-MB-231 cells assessed as inhibit cell proliferation incubated for 72 hrs by CCK-8 assay	[PMID: 36324491]
MDA-MB-231	IC₅₀	77.28 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition after 48 hrs by WST-1 assay	[PMID: 25466196]
MDA-MB-231	IC₅₀	8.704 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT reagent based ELISA Antiproliferative activity against human MDA-MB-231 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT reagent based ELISA	[PMID: 37556946]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 144 hrs by crystal violet staining method	[PMID: 22450132]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by crystal violet staining method	[PMID: 22765897]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining Cytotoxicity against human MDA-MB-231 cells after 72 hrs by crystal violet staining	[PMID: 22959205]
MDA-MB-231	IC₅₀	9.6 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-231 cells after 72 hrs Cytotoxicity against human MDA-MB-231 cells after 72 hrs	[PMID: 17336074]
MDA-MB-231	IC₅₀	9.89 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay Antiproliferative activity against human MDA-MB-231 cells assessed as cell growth inhibition incubated for 4 hrs by MTT assay	[PMID: 32992255]
MDA-MB-231	IC₅₀	93.8 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31803401]
MDA-MB-231	IC₅₀	97.04 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition Cytotoxicity against human MDA-MB-231 cells assessed as cell growth inhibition	[PMID: 35964428]
MDA-MB-231	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTS assay Cytotoxicity against human MDA-MB-231 cells assessed as reduction in cell viability after 72 hrs by MTS assay	[PMID: 30472605]
MDA-MB-231	IC₅₀	> 50 μM Compound: 5-Fu	Antiproliferative activity against human MDA-MB-231 cells by CCK8 assay Antiproliferative activity against human MDA-MB-231 cells by CCK8 assay	[PMID: 37939862]
MDA-MB-435	GI₅₀	0.07 μM Compound: 5-FU	Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MDA-MB-435 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MDA-MB-435	GI₅₀	0.07 μM Compound: 5-FU	Anticancer activity against human MDA-MB-435 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MDA-MB-435 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MDA-MB-435	IC₅₀	0.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human MDA-MB-435 cells assessed as cell growth inhibition Cytotoxicity against human MDA-MB-435 cells assessed as cell growth inhibition	[PMID: 36470105]
MDA-MB-435	IC₅₀	1.95 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-435 cells assessed as cell growth inhibition in presence of piperlongumine Antiproliferative activity against human MDA-MB-435 cells assessed as cell growth inhibition in presence of piperlongumine	[PMID: 33930801]
MDA-MB-435	IC₅₀	25.6 μg/mL Compound: 5-F	Cytotoxicity against human MDA-MB-435 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-435 cells after 48 hrs by MTT assay	[PMID: 24342667]
MDA-MB-435	IC₅₀	9.19 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-435 cells assessed as cell growth inhibition Antiproliferative activity against human MDA-MB-435 cells assessed as cell growth inhibition	[PMID: 33930801]
MDA-MB-435S	IC₅₀	14.5 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT method	[PMID: 17524655]
MDA-MB-435S	IC₅₀	14.5 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435S cells after 72 hrs by MTT assay	[PMID: 23792763]
MDA-MB-435S	IC₅₀	15.19 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-435S cells after 72 hrs by MTT assay	[PMID: 26595184]
MDA-MB-435S	IC₅₀	15.2 μM Compound: 5-FU	Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay Cytotoxicity against human MDA-MB-435S cells measured after 72 hrs by MTT assay	[PMID: 27537924]
MDA-MB-453	IC₅₀	7.4 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-453 cells Antiproliferative activity against human MDA-MB-453 cells	[PMID: 34655985]
MDA-MB-453	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-453 cells after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-453 cells after 72 hrs by MTT assay	[PMID: 22079378]
MDA-MB-468	IC₅₀	44.6 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by trypan blue exclusion assay	[PMID: 29133037]
MDA-MB-468	IC₅₀	44.9 μM Compound: 5-fluorouracil	Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133037]
MDA-MB-468	IC₅₀	7.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human MDA-MB-468 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31546197]
MDA-MB-468	IC₅₀	95.69 μM Compound: Fluorouracil	Cytotoxicity against human MDA-MB-468 cells after 48 hrs by MTT assay Cytotoxicity against human MDA-MB-468 cells after 48 hrs by MTT assay	[PMID: 28789892]
MDA-MB-468	IC₅₀	> 20 μM Compound: 5-Fu	Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay Cytotoxicity against human MDA-MB-468 cells assessed as reduction in cell viability incubated for 24 hrs by CellTiter-Glo luminescent assay	[PMID: 34516133]
MDA-MB-468	IC₅₀	> 200 μM Compound: 5-FU	Antiproliferative activity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MDA-MB-468 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35797901]
MDCK	EC₅₀	23 μg/mL Compound: 18b	Antiviral activity against Influenza B virus Florida/4/2006 infected in MDCK cells Antiviral activity against Influenza B virus Florida/4/2006 infected in MDCK cells	[PMID: 20674371]
MDCK	EC₅₀	26 μg/mL Compound: 18b	Antiviral activity against Influenza A virus H5N1 Vietnam/1203/2004H infected in MDCK cells Antiviral activity against Influenza A virus H5N1 Vietnam/1203/2004H infected in MDCK cells	[PMID: 20674371]
MDCK	IC₅₀	> 100 μg/mL Compound: 18b	Cytotoxicity against MDCK cells Cytotoxicity against MDCK cells	[PMID: 20674371]
ME-180	IC₅₀	4.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human ME180 cells after 48 hrs by MTT assay Cytotoxicity against human ME180 cells after 48 hrs by MTT assay	[PMID: 24332497]
MES-SA	IC₅₀	1.1 μM Compound: 5-FU	Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay Antiproliferative activity against human MES-SA cells after 72 hrs by MTT assay	[PMID: 19743863]
MFE-296	IC₅₀	30.68 μM Compound: 5FU	Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay Cytotoxicity against human MFE296 cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
MG-63	IC₅₀	8 μM Compound: 5-FU	Cytotoxicity against human MG63 cells after 3 days by MTT assay Cytotoxicity against human MG63 cells after 3 days by MTT assay	[PMID: 21612935]
MGC-803	EC₅₀	3.35 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 26883149]
MGC-803	IC₅₀	1.25 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
MGC-803	IC₅₀	1.8 μg/mL Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29100732]
MGC-803	IC₅₀	10 μM Compound: 5-Fu	Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Anticancer activity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 25086915]
MGC-803	IC₅₀	10.14 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay Cytotoxicity against human MGC803 cells assessed as growth inhibition by MTT assay	[PMID: 27769034]
MGC-803	IC₅₀	10.14 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
MGC-803	IC₅₀	10.14 μM Compound: 5-Fu	Antitumor activity against human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36931124]
MGC-803	IC₅₀	10.27 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by SRB assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by SRB assay	[PMID: 35594653]
MGC-803	IC₅₀	10.36 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells Antiproliferative activity against human MGC-803 cells	[PMID: 34655985]
MGC-803	IC₅₀	10.64 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
MGC-803	IC₅₀	10.72 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 25707012]
MGC-803	IC₅₀	11.34 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 24835817]
MGC-803	IC₅₀	12.14 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34624825]
MGC-803	IC₅₀	12.6 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 3 days by MTT assay Cytotoxicity against human MGC803 cells after 3 days by MTT assay	[PMID: 21144621]
MGC-803	IC₅₀	14 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human MGC803 cells assessed as reduction in cell viability by MTT assay	[PMID: 31029946]
MGC-803	IC₅₀	14.1 μM Compound: 5-fluorouracil	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 36893627]
MGC-803	IC₅₀	14.15 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 29133051]
MGC-803	IC₅₀	15.32 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 24211021]
MGC-803	IC₅₀	15.7 μM Compound: 5-FU	Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 37859725]
MGC-803	IC₅₀	16.6 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 22079378]
MGC-803	IC₅₀	18.5 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 22749192]
MGC-803	IC₅₀	18.63 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells measured after 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells measured after 48 hrs by MTT assay	[PMID: 32135407]
MGC-803	IC₅₀	24.803 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells by MTT assay Antiproliferative activity against human MGC-803 cells by MTT assay	[PMID: 32810752]
MGC-803	IC₅₀	25.54 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29316536]
MGC-803	IC₅₀	26.35 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 37859725]
MGC-803	IC₅₀	27.56 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
MGC-803	IC₅₀	28.6 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 35286954]
MGC-803	IC₅₀	29.15 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
MGC-803	IC₅₀	3.12 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 28165738]
MGC-803	IC₅₀	3.38 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells incubated for 72 hrs by MTT assay	[PMID: 31404863]
MGC-803	IC₅₀	3.42 μM Compound: 5-Fluorouracil	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 22405648]
MGC-803	IC₅₀	3.45 μM Compound: 5-Fu	Anticancer activity against human MGC803 cells after 72 hrs by MTT assay Anticancer activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 25001482]
MGC-803	IC₅₀	3.58 μM Compound: 5-Fluorouracil	Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human MGC803 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
MGC-803	IC₅₀	3.68 μM Compound: 5-Fluorouracil	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 24119869]
MGC-803	IC₅₀	3.71 μM Compound: 5-Fluorouracil	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 25554922]
MGC-803	IC₅₀	3.79 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
MGC-803	IC₅₀	3.88 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 38759254]
MGC-803	IC₅₀	30.45 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 25462253]
MGC-803	IC₅₀	31.04 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 30142612]
MGC-803	IC₅₀	34.85 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells by MTT assay Antiproliferative activity against human MGC-803 cells by MTT assay	[PMID: 33109400]
MGC-803	IC₅₀	34.85 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells incubated for 48 hrs by MTT assay	[PMID: 37972528]
MGC-803	IC₅₀	38.49 μM Compound: 5-FU	Cytotoxicity against human MGC-803 cells assessed as cell growth inhibition Cytotoxicity against human MGC-803 cells assessed as cell growth inhibition	[PMID: 35809817]
MGC-803	IC₅₀	39.1 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
MGC-803	IC₅₀	4.55 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
MGC-803	IC₅₀	40.94 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
MGC-803	IC₅₀	44.05 μM Compound: 5-fluorouracil	Inhibition of cell proliferation in human MGC-803 cells incubated for 72 hrs by MTT assay Inhibition of cell proliferation in human MGC-803 cells incubated for 72 hrs by MTT assay	[PMID: 39285177]
MGC-803	IC₅₀	46.93 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 25151580]
MGC-803	IC₅₀	46.93 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 24953029]
MGC-803	IC₅₀	47.39 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 2 days by MTT assay Cytotoxicity against human MGC803 cells after 2 days by MTT assay	[PMID: 25841196]
MGC-803	IC₅₀	5.81 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
MGC-803	IC₅₀	58 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 31057737]
MGC-803	IC₅₀	6.06 μM Compound: 5-FU	Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
MGC-803	IC₅₀	6.22 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34455358]
MGC-803	IC₅₀	6.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MGC803 cells by MTT assay Antiproliferative activity against human MGC803 cells by MTT assay	[PMID: 31546197]
MGC-803	IC₅₀	6.52 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
MGC-803	IC₅₀	6.56 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 30108876]
MGC-803	IC₅₀	6.56 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 28456031]
MGC-803	IC₅₀	6.82 μM Compound: 5-FU	Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human MGC-803 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
MGC-803	IC₅₀	6.82 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32682200]
MGC-803	IC₅₀	6.89 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 28759876]
MGC-803	IC₅₀	6.9 μM Compound: 5-fluorouracil	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth by MTT assay	[PMID: 36893627]
MGC-803	IC₅₀	6.92 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 23792764]
MGC-803	IC₅₀	6.92 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
MGC-803	IC₅₀	62.5 μM Compound: 5-FU	Cytotoxicity against human MGC-803 cells assessed as cell growth inhibition Cytotoxicity against human MGC-803 cells assessed as cell growth inhibition	[PMID: 35964428]
MGC-803	IC₅₀	62.51 μM Compound: 5-Fu	Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human MGC-803 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
MGC-803	IC₅₀	68.3 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 26714048]
MGC-803	IC₅₀	7.01 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 23353743]
MGC-803	IC₅₀	7.14 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 23644193]
MGC-803	IC₅₀	7.21 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27423479]
MGC-803	IC₅₀	7.21 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 28038329]
MGC-803	IC₅₀	7.21 μM Compound: 5-Fu	Antitumor activity human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity human MGC-803 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36216031]
MGC-803	IC₅₀	7.22 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	10.1039/C6MD00169F
MGC-803	IC₅₀	7.35 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 27771599]
MGC-803	IC₅₀	7.52 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28838695]
MGC-803	IC₅₀	7.52 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28863355]
MGC-803	IC₅₀	7.52 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29113745]
MGC-803	IC₅₀	7.54 μM Compound: 5-FU	Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human MGC-803 cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
MGC-803	IC₅₀	7.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MGC-803 cells Antiproliferative activity against human MGC-803 cells	[PMID: 33421712]
MGC-803	IC₅₀	7.69 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25180925]
MGC-803	IC₅₀	7.76 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 25113877]
MGC-803	IC₅₀	7.86 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29407946]
MGC-803	IC₅₀	74.39 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 30108924]
MGC-803	IC₅₀	8.13 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 24798098]
MGC-803	IC₅₀	8.43 μM Compound: 5-Fu	Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay Anticancer activity against human MGC803 cells assessed as inhibition of proliferation after 72 hrs by MTT assay	[PMID: 25655718]
MGC-803	IC₅₀	8.66 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29635165]
MGC-803	IC₅₀	8.66 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
MGC-803	IC₅₀	9.05 μM Compound: 5-FU	Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
MGC-803	IC₅₀	9.2 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells assessed as reduction in cell viability after 72 hrs by MTT assay	10.1039/C5MD00240K
MGC-803	IC₅₀	9.24 μM Compound: 5-Fu	Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 29475156]
MGC-803	IC₅₀	9.79 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 28763643]
MGC-803	IC₅₀	9.79 μM Compound: 5-FU	Antiproliferative activity against human MGC803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human MGC803 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 31740251]
MGC-803	IC₅₀	9.95 μM Compound: 5-Fu	Antiproliferative activity against human MGC-803 cells measured after 72 hrs by MTT assay Antiproliferative activity against human MGC-803 cells measured after 72 hrs by MTT assay	[PMID: 37379957]
MGC-803	IC₅₀	93.53 μM Compound: 5-FU	Cytotoxicity in human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human MGC-803 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 35085721]
MGC-803	IC₅₀	> 50 μM Compound: 5-FU	Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay Cytotoxicity against human MGC803 cells after 72 hrs by MTT assay	[PMID: 30677614]
MGC-803	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human MGC-803 cells incubated for 72 hrs by MTT assay Anticancer activity against human MGC-803 cells incubated for 72 hrs by MTT assay	[PMID: 35367708]
MGC-803	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay Cytotoxicity against human MGC803 cells after 48 hrs by MTT assay	[PMID: 29174813]
MIA PaCa-2	GI₅₀	30 μM Compound: 5-Fu	Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay	[PMID: 22512908]
MIA PaCa-2	GI₅₀	30.6 nM Compound: 5FU	Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay Growth inhibition of human MIAPaCa2 cells after 48 hrs by SRB assay	[PMID: 23094992]
MIA PaCa-2	GI₅₀	> 10 μM Compound: 5-Fu	Growth inhibition of human MIAPaCa2 cells after 72 hrs by Alamar Blue assay Growth inhibition of human MIAPaCa2 cells after 72 hrs by Alamar Blue assay	[PMID: 19406645]
MIA PaCa-2	IC₅₀	10 μM Compound: 5-FU	Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay Growth inhibition of human MIAPaCa2 cells after 72 hrs by MTT assay	[PMID: 18640746]
MIA PaCa-2	IC₅₀	11.45 μM Compound: 5-FU	Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay	[PMID: 21524829]
MIA PaCa-2	IC₅₀	11.67 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
MIA PaCa-2	IC₅₀	11.67 μM Compound: 5-Fluoruracil	Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay Antiproliferative activity against human MIAPaCa2 cells after 72 hrs by MTT assay	[PMID: 22555152]
MIA PaCa-2	IC₅₀	14 μM Compound: 5-FU	Antiproliferative activity against human MIAPaCa2 cells after 48 hrs Antiproliferative activity against human MIAPaCa2 cells after 48 hrs	[PMID: 21458113]
MIA PaCa-2	IC₅₀	24.267 μM Compound: 5-Fluorouracil	Cytotoxicity against human MIAPaCa2 cells incubated for 24 hrs by MTT assay Cytotoxicity against human MIAPaCa2 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
MIA PaCa-2	IC₅₀	3.5 μg/mL Compound: 5-Fu	Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human MIAPaCa2 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
MIA PaCa-2	IC₅₀	6.5 μM Compound: 5-FU	Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay Antiproliferative activity against human MiaPaCa2 cells after 3 days by MTT assay	[PMID: 18424155]
MIA PaCa-2	IC₅₀	7.4 μM Compound: 5-FU	Antiproliferative activity against human MIAPaCa2 cells after 72 hrs Antiproliferative activity against human MIAPaCa2 cells after 72 hrs	[PMID: 21458113]
MKN-1	IC₅₀	3.88 μM Compound: 5-Fu	Antiproliferative activity against human MKN-1 cells incubated for 72 hrs by SRB method Antiproliferative activity against human MKN-1 cells incubated for 72 hrs by SRB method	[PMID: 39054645]
MKN-28	IC₅₀	2.5 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of MKN-28 tumor cell line from stomach. Compound was tested for its inhibitory effect on the growth of MKN-28 tumor cell line from stomach.	10.1016/0960-894X(96)00339-3
MKN-28	IC₅₀	6.9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MKN28 cells by MTT assay Antiproliferative activity against human MKN28 cells by MTT assay	[PMID: 31546197]
MKN-28	IC₅₀	6.9 μM Compound: 5-fluorouracil	Antiproliferative activity against human MKN-28 cells assessed as inhibition of cell growth by MTT assay Antiproliferative activity against human MKN-28 cells assessed as inhibition of cell growth by MTT assay	[PMID: 36893627]
MKN-28	IC₅₀	9.67 μM Compound: 5-fluorouracil	Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay Cytotoxicity against human MKN28 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25506718]
MKN-45	IC₅₀	21.4 μM Compound: 5-FU	Cytotoxicity against human MNK45 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human MNK45 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
MKN-45	IC₅₀	3 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of MKN-45 tumor cell line from stomach. Compound was tested for its inhibitory effect on the growth of MKN-45 tumor cell line from stomach.	10.1016/0960-894X(96)00339-3
MKN-45	IC₅₀	3.6 x 10^-1 μg/mL Compound: fluorouracil	Cytotoxicity against human MKN45 cells by MTT assay Cytotoxicity against human MKN45 cells by MTT assay	[PMID: 22011319]
MKN-45	IC₅₀	41.73 μM Compound: Fluorouracil	Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay Cytotoxicity against human MKN45 cells after 48 hrs by MTT assay	[PMID: 22809558]
MKN-45	IC₅₀	6.9 μM Compound: 5-Fluorouracil	Antiproliferative activity against human MKN45 cells by MTT assay Antiproliferative activity against human MKN45 cells by MTT assay	[PMID: 31546197]
MKN-45	IC₅₀	6.9 μM Compound: 5-fluorouracil	Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth by MTT assay Antiproliferative activity against human MKN-45 cells assessed as inhibition of cell growth by MTT assay	[PMID: 36893627]
MKN-45	IC₅₀	8.89 μM Compound: 5-FU	Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay	[PMID: 28838695]
MKN-45	IC₅₀	8.89 μM Compound: 5-FU	Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay Antiproliferative activity against human MKN45 cells after 48 hrs by MTT assay	[PMID: 28863355]
MKN-45	IC₅₀	8.89 μM Compound: 5-Fu	Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay Antiproliferative activity against human MKN45 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29113745]
MOLT-3	ED₅₀	2.14 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human TMOLT3 cells after 3 days by trypan blue exclusion technique Cytotoxicity against human TMOLT3 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
MOLT-3	IC₅₀	1.2 μg/mL Compound: 5-F-Ura	In vitro antitumor activity in MOLT-3 cell lines In vitro antitumor activity in MOLT-3 cell lines	[PMID: 8648611]
MOLT-4	ED₅₀	15.07 μM Compound: 5-Fluorouracil	Cytotoxicity against human MOLT4 cells after 6 hrs by Alamar Blue assay Cytotoxicity against human MOLT4 cells after 6 hrs by Alamar Blue assay	[PMID: 24020806]
MOLT-4	ED₅₀	7.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human MOLT4 cells by Alamar blue assay Cytotoxicity against human MOLT4 cells by Alamar blue assay	[PMID: 24128077]
MOLT-4	GI₅₀	0.35 μM Compound: 5-FU	Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MOLT4 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
MOLT-4	GI₅₀	0.35 μM Compound: 5-FU	Anticancer activity against human MOLT-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human MOLT-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
MOLT-4	IC₅₀	0.03 μM Compound: 5-FU	Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay Antitumor activity against human MOLT4 cells after 24 hrs by MTT assay	[PMID: 20211564]
MOLT-4	IC₅₀	0.35 μM Compound: 5-Fluorouracil	Cytotoxicity against human MOLT-4 cells assessed as cell growth inhibition Cytotoxicity against human MOLT-4 cells assessed as cell growth inhibition	[PMID: 36470105]
MOLT-4	IC₅₀	2.9 μg/mL Compound: 5-FU	Evaluated for the inhibition of tumor cell growth of Human T-Lymphocyte cells (Molt4/C8) Evaluated for the inhibition of tumor cell growth of Human T-Lymphocyte cells (Molt4/C8)	[PMID: 11123990]
MOLT-4	IC₅₀	20 μM Compound: 5-FU	Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay Antiproliferative activity against human Molt4/C8 cells after 3 days by MTT assay	[PMID: 18424155]
MOLT-4	IC₅₀	23 μM Compound: 5-Fluorouracil	Concentration required to inhibit 50% of cell growth on human Molt 4/C8 cells. Concentration required to inhibit 50% of cell growth on human Molt 4/C8 cells.	[PMID: 11052798]
MOLT-4	IC₅₀	23 μM Compound: 5-Fluorouracil	Cytostatic activity against human Molt4/C8 cells Cytostatic activity against human Molt4/C8 cells	[PMID: 17931862]
MOLT-4	IC₅₀	3.2 μM Compound: 5-Fu	Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human MOLT4 cells after 48 hrs by sulforhodamine B assay	[PMID: 22424614]
MOLT-4	IC₅₀	3.8 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of cell growth of MOLT-4 leukemic cell lines in human. Concentration required for 50% inhibition of cell growth of MOLT-4 leukemic cell lines in human.	[PMID: 1992123]
MOLT-4	IC₅₀	3.8 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human T-cell acute lymphoblastic leukemia (MOLT-4) cell line. In vitro inhibitory activity against Human T-cell acute lymphoblastic leukemia (MOLT-4) cell line.	[PMID: 1995905]
MOLT-4	IC₅₀	3.8 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of human T-cell acute lymphoblastic leukemic MOLT 4 cell lines. In vitro inhibitory effect on growth of human T-cell acute lymphoblastic leukemic MOLT 4 cell lines.	[PMID: 3373480]
MOLT-4	IC₅₀	6.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against human MOLT4 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
MRC5	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human MRC5 cells after 48 hrs by SRB assay Growth inhibition of human MRC5 cells after 48 hrs by SRB assay	[PMID: 28400235]
MRC5	IC₅₀	245.65 μM Compound: 5-FU	Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human MRC5 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36758308]
Mahlavu	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay	[PMID: 29326016]
Mahlavu	IC₅₀	10 μM Compound: 5-Fu	Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay	[PMID: 22409771]
Malme-3M	GI₅₀	0.05 μM Compound: 5-FU	Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay Growth inhibition of human MALME-3M cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
Malme-3M	GI₅₀	0.05 μM Compound: 5-FU	Anticancer activity against human Malme-3M cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human Malme-3M cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
Malme-3M	IC₅₀	0.05 μM Compound: 5-Fluorouracil	Cytotoxicity against human Malme-3M cells assessed as cell growth inhibition Cytotoxicity against human Malme-3M cells assessed as cell growth inhibition	[PMID: 36470105]
MeWo	IC₅₀	8 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human MeWo cells by MTT assay Cytotoxicity against human MeWo cells by MTT assay	[PMID: 29280630]
Melanoma cell	CC₅₀	46.1 μM Compound: 5-FU	Cytotoxicity against human skin melanoma cells after 72 hrs Cytotoxicity against human skin melanoma cells after 72 hrs	[PMID: 17337193]
Melanoma cell	CC₅₀	46.1 μM Compound: 5-Fu	Cytotoxicity against human melanoma cells after 72 hrs Cytotoxicity against human melanoma cells after 72 hrs	[PMID: 18037195]
Melanoma cell	CC₅₀	46.1 μM Compound: 5FU	Cytotoxicity against human melanoma cells after 72 hrs Cytotoxicity against human melanoma cells after 72 hrs	[PMID: 17548129]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Growth inhibition of human melanoma cells after 48 hrs Growth inhibition of human melanoma cells after 48 hrs	[PMID: 18950904]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by coulter counting Cytotoxicity against human melanoma cells after 48 hrs by coulter counting	[PMID: 22056277]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Growth inhibition of human Melanoma cells after 48 hrs by coulter counter method Growth inhibition of human Melanoma cells after 48 hrs by coulter counter method	[PMID: 22119151]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by sulphorhodamine B assay Cytotoxicity against human melanoma cells after 48 hrs by sulphorhodamine B assay	[PMID: 23474899]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by coulter counter analysis Cytotoxicity against human melanoma cells after 48 hrs by coulter counter analysis	[PMID: 23683592]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells after 48 hrs by SRB assay Cytotoxicity against human melanoma cells after 48 hrs by SRB assay	[PMID: 23994328]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Cytotoxicity against human melanoma cells at 10 uM after 48 hrs Cytotoxicity against human melanoma cells at 10 uM after 48 hrs	[PMID: 24469112]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-FU	Growth inhibition of human melanoma cells after 48 hrs by SRB assay Growth inhibition of human melanoma cells after 48 hrs by SRB assay	[PMID: 27554444]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-fu	Antitumor activity against human melanoma cells after 48 hrs by SRB assay Antitumor activity against human melanoma cells after 48 hrs by SRB assay	[PMID: 20350811]
Melanoma cell	GI₅₀	70.6 μM Compound: 5-fu	Antiproliferative activity against human melanoma cells after 48 hrs by cell counting analysis Antiproliferative activity against human melanoma cells after 48 hrs by cell counting analysis	[PMID: 22995621]
Mononuclear cell line	IC₅₀	429.8 μM Compound: 5-FU	Cytotoxicity against patient-derived human mononuclear cells assessed as cell growth inhibition incubated for 72 hrs by FMCA assay Cytotoxicity against patient-derived human mononuclear cells assessed as cell growth inhibition incubated for 72 hrs by FMCA assay	[PMID: 36018000]
N2a	IC₅₀	1.2 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay Cytotoxicity against mouse Neuro2a cells assessed as cell growth inhibition by MTT assay	[PMID: 26629861]
N592	IC₅₀	5.4 μM Compound: 5-FluoroUracil	Cytotoxicity against human small-cell lung cancer (SCLC) Cytotoxicity against human small-cell lung cancer (SCLC)	[PMID: 8258835]
NCI-H1299	IC₅₀	3.53 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1299 cells Antiproliferative activity against human NCI-H1299 cells	[PMID: 35944853]
NCI-H1299	IC₅₀	8.91 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay Antiproliferative activity against human NCI-H1299 cells after 48 hrs by MTS assay	[PMID: 28152430]
NCI-H1650	IC₅₀	12.52 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay	[PMID: 30108876]
NCI-H1650	IC₅₀	12.52 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay	[PMID: 28456031]
NCI-H1650	IC₅₀	14.25 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay	[PMID: 28838695]
NCI-H1650	IC₅₀	14.25 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 48 hrs by MTT assay	[PMID: 28863355]
NCI-H1650	IC₅₀	14.25 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 29113745]
NCI-H1650	IC₅₀	14.63 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1650 cells after 72 hrs by MTT assay	[PMID: 29407946]
NCI-H1650	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human NCI-H1650 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
NCI-H1975	IC₅₀	1.98 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1975 cells Antiproliferative activity against human NCI-H1975 cells	[PMID: 35944853]
NCI-H1975	IC₅₀	2.67 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
NCI-H1975	IC₅₀	9.37 μM Compound: 5-FU	Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human NCI-H1975 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
NCI-H226	GI₅₀	54.7 μM Compound: 5-FU	Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H226 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H226	GI₅₀	54.7 μM Compound: 5-FU	Anticancer activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H226	IC₅₀	54.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human NCI-H226 cells assessed as cell growth inhibition Cytotoxicity against human NCI-H226 cells assessed as cell growth inhibition	[PMID: 36470105]
NCI-H23	GI₅₀	0.33 μM Compound: 5-FU	Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H23 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H23	GI₅₀	0.33 μM Compound: 5-FU	Anticancer activity against human NCI-H23 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H23 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H23	IC₅₀	0.33 μM Compound: 5-Fluorouracil	Cytotoxicity against human NCI-H23 cells assessed as cell growth inhibition Cytotoxicity against human NCI-H23 cells assessed as cell growth inhibition	[PMID: 36470105]
NCI-H358	IC₅₀	6.9 μg/mL Compound: 5-Fu	Cytotoxicity against human NCI-H358 cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human NCI-H358 cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
NCI-H358	IC₅₀	> 20 μM Compound: 5-Fu	Cytotoxicity against human NCI-H358 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human NCI-H358 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
NCI-H460	GI₅₀	0.05 μM Compound: 5-FU	Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H460 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H460	GI₅₀	0.05 μM Compound: 5-FU	Anticancer activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H460 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H460	GI₅₀	0.3 μg/mL Compound: 5FU	Cytotoxicity against human H460 cells assessed as growth inhibition after 48 hrs by SRB assay method Cytotoxicity against human H460 cells assessed as growth inhibition after 48 hrs by SRB assay method	[PMID: 26383125]
NCI-H460	GI₅₀	2.3 μM Compound: 5FU	Cytotoxicity against human NCI-H460 cells Cytotoxicity against human NCI-H460 cells	[PMID: 20356752]
NCI-H460	GI₅₀	4.1 μM Compound: 5FU	Cytotoxicity against human H460 cells after 48 hrs Cytotoxicity against human H460 cells after 48 hrs	[PMID: 18798609]
NCI-H460	GI₅₀	5.95 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay Cytotoxicity against human NCI-H460 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
NCI-H460	GI₅₀	6.5 μM Compound: 5-Fu	Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay Growth inhibition of human NCI-H460 cells after 48 hrs by SRB assay	[PMID: 22512908]
NCI-H460	IC₅₀	0.05 μM Compound: 5-Fluorouracil	Cytotoxicity against human NCI-H460 cells assessed as cell growth inhibition Cytotoxicity against human NCI-H460 cells assessed as cell growth inhibition	[PMID: 36470105]
NCI-H460	IC₅₀	0.54 μM Compound: 5-fluorouracil	Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability by SRB assay	[PMID: 30660827]
NCI-H460	IC₅₀	11.75 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 30318440]
NCI-H460	IC₅₀	2 μM Compound: 5-FU	Growth inhibition of human H460 cells after 72 hrs by MTT assay Growth inhibition of human H460 cells after 72 hrs by MTT assay	[PMID: 18640746]
NCI-H460	IC₅₀	2 μM Compound: 5-FU	Antitumor activity against human H460 cells after 24 hrs by MTT assay Antitumor activity against human H460 cells after 24 hrs by MTT assay	[PMID: 20211564]
NCI-H460	IC₅₀	2.4 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 22727445]
NCI-H460	IC₅₀	2.48 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 24021891]
NCI-H460	IC₅₀	2.7 μM Compound: 5-FU	Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay Antiproliferative activity against human H460 cells after 24 hrs by trypan blue exclusion assay	[PMID: 20403701]
NCI-H460	IC₅₀	23.32 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 24211021]
NCI-H460	IC₅₀	24.84 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36758308]
NCI-H460	IC₅₀	26.34 μM Compound: 5-FU	Antiproliferative activity against human NCI-H460 cells Antiproliferative activity against human NCI-H460 cells	[PMID: 34655985]
NCI-H460	IC₅₀	26.7 μM Compound: 5-FU	Cytotoxicity against human H460 cells after 48 hrs by MTT assay Cytotoxicity against human H460 cells after 48 hrs by MTT assay	[PMID: 23867385]
NCI-H460	IC₅₀	29 μM Compound: 5-fu	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 22304344]
NCI-H460	IC₅₀	3 μM Compound: 5-FU	Cytotoxicity against human H460 cells after 72 hrs by MTT assay Cytotoxicity against human H460 cells after 72 hrs by MTT assay	[PMID: 22130132]
NCI-H460	IC₅₀	3 μM Compound: 5-Fluorouracil	Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay Cytostatic activity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 22405290]
NCI-H460	IC₅₀	35.52 μM Compound: 5-FU	Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human NCI-H460 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
NCI-H460	IC₅₀	36 μM Compound: 5-FU	Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay Antiproliferative activity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 28756264]
NCI-H460	IC₅₀	36.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 24565905]
NCI-H460	IC₅₀	36.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 25462253]
NCI-H460	IC₅₀	44.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 23988357]
NCI-H460	IC₅₀	44.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay Cytotoxicity against human NCI-H460 cells after 3 days by MTT assay	[PMID: 24095745]
NCI-H460	IC₅₀	44.04 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 25151580]
NCI-H460	IC₅₀	45.14 μM Compound: 5-Fu	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 24953029]
NCI-H460	IC₅₀	45.44 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 30092368]
NCI-H460	IC₅₀	45.44 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay	[PMID: 30108826]
NCI-H460	IC₅₀	46.15 μM Compound: 5-Fu	Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay Cytotoxicity against human NCI-H460 cells after 2 days by MTT assay	[PMID: 25841196]
NCI-H460	IC₅₀	7.03 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell growth by CCK8 assay Antiproliferative activity against human NCI-H460 cells assessed as reduction in cell growth by CCK8 assay	[PMID: 33964443]
NCI-H460	IC₅₀	7.03 μM Compound: 5-Fu	Antiproliferative activity against human NCI-H460 cells Antiproliferative activity against human NCI-H460 cells	[PMID: 35944853]
NCI-H460	IC₅₀	7.2 μg/mL Compound: 5-FU	Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay Cytotoxicity against human NCI-H460 cells after 72 hrs by MTT assay	[PMID: 22647218]
NCI-H460	IC₅₀	8 μM Compound: 5-Fu	Cytotoxicity against human NCI-H460 cells Cytotoxicity against human NCI-H460 cells	[PMID: 22283451]
NCI-H460	IC₅₀	8.5 μM Compound: 5-FU	Antiproliferative activity against human NCI-H460 cells after 48 by hrs MTT assay Antiproliferative activity against human NCI-H460 cells after 48 by hrs MTT assay	[PMID: 29305189]
NCI-H460	IC₅₀	8.5 μM Compound: Fluorouracil	Cytotoxicity against human NCI-H460 cells Cytotoxicity against human NCI-H460 cells	[PMID: 21774474]
NCI-H460	IC₅₀	8.5 μM Compound: Fluorouracil	Cytotoxic activity against human NCI-H460 cells Cytotoxic activity against human NCI-H460 cells	[PMID: 24195466]
NCI-H460	IC₅₀	9.9 μM Compound: 5-FU	Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human NCI-H460 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
NCI-H508	IC₅₀	8.8 μM Compound: 5-FU	Antiproliferative activity against human NCI-H508 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human NCI-H508 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
NCI-H522	GI₅₀	7.27 μM Compound: 5-FU	Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-H522 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI-H522	GI₅₀	7.27 μM Compound: 5-FU	Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI-H522 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI-H522	GI₅₀	7.28 μM Compound: 5-FU	Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay Cytotoxicity against human NCI-H522 cells after 48 hrs by SRB assay	[PMID: 22305543]
NCI-H522	IC₅₀	55.6 μM Compound: 5-FU	Growth inhibition of human NCI-H522 cells after 24 hrs by MTT assay Growth inhibition of human NCI-H522 cells after 24 hrs by MTT assay	[PMID: 28011220]
NCI-H522	IC₅₀	56.76 μM Compound: 5-FU	Cytotoxicity against human NCI-H522 cells after 24 hrs by MTT assay Cytotoxicity against human NCI-H522 cells after 24 hrs by MTT assay	[PMID: 23202484]
NCI-H522	IC₅₀	7.27 μM Compound: 5-Fluorouracil	Cytotoxicity against human NCI-H522 cells assessed as cell growth inhibition Cytotoxicity against human NCI-H522 cells assessed as cell growth inhibition	[PMID: 36470105]
NCI-H69	GI₅₀	100 μM Compound: 5-Fu	Growth inhibition of human NCI-H69 cells after 48 hrs by SRB assay Growth inhibition of human NCI-H69 cells after 48 hrs by SRB assay	[PMID: 22512908]
NCI-H69	IC₅₀	0.28 mg/mL Compound: 5-Fu	Cytotoxicity against human NCI-H69 cells after 3 days MTT assay Cytotoxicity against human NCI-H69 cells after 3 days MTT assay	[PMID: 22796042]
NCI/ADR-RES	GI₅₀	0.31 μM Compound: 5-FU	Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay Growth inhibition of human NCI-ADR-RES cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
NCI/ADR-RES	GI₅₀	0.31 μM Compound: 5-FU	Anticancer activity against human NCI/ADR-RES cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human NCI/ADR-RES cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
NCI/ADR-RES	IC₅₀	0.31 μM Compound: 5-Fluorouracil	Cytotoxicity against human NCI/ADR-RES cells assessed as cell growth inhibition Cytotoxicity against human NCI/ADR-RES cells assessed as cell growth inhibition	[PMID: 36470105]
NCI/ADR-RES	IC₅₀	512.78 μM Compound: 5-FU	Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay Cytotoxicity against human MCF7/ADR cells after 72 hrs by MTT assay	[PMID: 30677614]
NCI/ADR-RES	IC₅₀	54.72 μM Compound: 5-FU	Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human MCF7/ADR cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 31673307]
NCI/ADR-RES	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity against multidrug-resistant human MCF7/ADR cells after 48 hrs by MTT assay Cytotoxicity against multidrug-resistant human MCF7/ADR cells after 48 hrs by MTT assay	[PMID: 22537362]
NCM460	EC₅₀	43.32 μM Compound: 5-FU	Cytotoxicity against human NCM460 cells assessed as cell viability measured after 72 hrs in presence of 5-FU by MTT assay Cytotoxicity against human NCM460 cells assessed as cell viability measured after 72 hrs in presence of 5-FU by MTT assay	[PMID: 34411894]
NCM460	IC₅₀	7.95 μM Compound: 5-FU	Cytotoxicity against human NCM460 cells incubated for 72 hrs by MTS assay Cytotoxicity against human NCM460 cells incubated for 72 hrs by MTS assay	[PMID: 38843656]
NCM460	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human NCM460 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay Antiproliferative activity against human NCM460 cells assessed as reduction in cell viability measured after 48 to 72 hrs by MTT assay	[PMID: 37659196]
NHDF	GI₅₀	62.02 nM Compound: 5FU	Growth inhibition of human NHDF cells after 48 hrs by SRB assay Growth inhibition of human NHDF cells after 48 hrs by SRB assay	[PMID: 23094992]
NHDF	IC₅₀	14.67 μM Compound: 5-FU	Antiproliferative activity against NHDF expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against NHDF expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
NHDF	IC₅₀	30 μM Compound: 5-FU	Antiproliferative activity against NHDF expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against NHDF expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
NHDF	IC₅₀	7.02 μM Compound: FUra	Cytotoxicity against HDF assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay Cytotoxicity against HDF assessed as reduction in cell survival after 72 hrs by sulforhodamine B assay	[PMID: 27501415]
NHDF	IC₅₀	7.38 μM Compound: 5-FU	Antiproliferative activity against NHDF after 72 hrs by MTT assay Antiproliferative activity against NHDF after 72 hrs by MTT assay	[PMID: 29223098]
NHDF	IC₅₀	70.4 μM Compound: 1; 5-FU	Cytotoxicity against NHDF assessed as reduction in cell viability measured after 48 hrs by SRB assay Cytotoxicity against NHDF assessed as reduction in cell viability measured after 48 hrs by SRB assay	[PMID: 33819035]
NHDF	IC₅₀	> 25 μM Compound: 5-Fluorouracil	Cytotoxicity against human NHDF cells incubated for 72 hrs by MTS assay Cytotoxicity against human NHDF cells incubated for 72 hrs by MTS assay	[PMID: 31158748]
NHDF	IC₅₀	> 50 μM Compound: 5-FU	Cytotoxicity against human NHDF cells assessed as reduction in cell viability Cytotoxicity against human NHDF cells assessed as reduction in cell viability	[PMID: 32127259]
NHDF	IC₅₀	> 50 μM Compound: 5-FU	Cytotoxicity against human NHDF cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human NHDF cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 37098306]
NIH3T3	GI₅₀	< 1.54 μM Compound: 5FU	Cytotoxicity against BALB mouse 3T3 cells after 48 hrs Cytotoxicity against BALB mouse 3T3 cells after 48 hrs	[PMID: 18798609]
NIH3T3	GI₅₀	< 3 μM Compound: 5FU	Cytotoxicity against BALB mouse 3T3 cells Cytotoxicity against BALB mouse 3T3 cells	[PMID: 20356752]
NIH3T3	IC₅₀	22.36 μM Compound: 5-Fluorouracil	Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay Antiproliferative activity against mouse NIH/3T3 cells assessed as inhibition of cell proliferation incubated for 48 hrs by CCK8 assay	[PMID: 25959813]
NSCLC	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human NSCLC cells after 48 hrs Growth inhibition of human NSCLC cells after 48 hrs	[PMID: 18950904]
NSCLC	GI₅₀	> 100 μM Compound: 5-FU	Cytotoxicity against human NSCLC cells after 48 hrs by coulter counting Cytotoxicity against human NSCLC cells after 48 hrs by coulter counting	[PMID: 22056277]
NSCLC	GI₅₀	> 100 μM Compound: 5-FU	Growth inhibition of human NSCLC cells after 48 hrs by coulter counter method Growth inhibition of human NSCLC cells after 48 hrs by coulter counter method	[PMID: 22119151]
NUGC-3	IC₅₀	4.4 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of NUGC-3 tumor cell line from stomach. Compound was tested for its inhibitory effect on the growth of NUGC-3 tumor cell line from stomach.	10.1016/0960-894X(96)00339-3
OVCAR-3	GI₅₀	0.01 μM Compound: 5-FU	Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-3	GI₅₀	0.01 μM Compound: 5-FU	Anticancer activity against human OVCAR-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-3	IC₅₀	0.01 μM Compound: 5-Fluorouracil	Cytotoxicity against human OVCAR-3 cells assessed as cell growth inhibition Cytotoxicity against human OVCAR-3 cells assessed as cell growth inhibition	[PMID: 36470105]
OVCAR-3	IC₅₀	18.86 μM Compound: 5-FU	Antiproliferative activity against human OVCAR-3 cells Antiproliferative activity against human OVCAR-3 cells	[PMID: 38716896]
OVCAR-3	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human OVCAR3 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
OVCAR-4	GI₅₀	4.43 μM Compound: 5-FU	Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR4 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-4	GI₅₀	4.43 μM Compound: 5-FU	Anticancer activity against human OVCAR-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-4 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-4	IC₅₀	4.43 μM Compound: 5-Fluorouracil	Cytotoxicity against human OVCAR-4 cells assessed as cell growth inhibition Cytotoxicity against human OVCAR-4 cells assessed as cell growth inhibition	[PMID: 36470105]
OVCAR-5	GI₅₀	10.9 μM Compound: 5-FU	Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR5 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-5	GI₅₀	10.9 μM Compound: 5-FU	Anticancer activity against human OVCAR-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-5	GI₅₀	20 μM Compound: 5-Fu	Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay	[PMID: 22512908]
OVCAR-5	GI₅₀	26.4 nM Compound: 5FU	Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay Growth inhibition of human OVCAR5 cells after 48 hrs by SRB assay	[PMID: 23094992]
OVCAR-5	IC₅₀	10.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human OVCAR-5 cells assessed as cell growth inhibition Cytotoxicity against human OVCAR-5 cells assessed as cell growth inhibition	[PMID: 36470105]
OVCAR-8	GI₅₀	1.74 μM Compound: 5-FU	Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human OVCAR8 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
OVCAR-8	GI₅₀	1.74 μM Compound: 5-FU	Anticancer activity against human OVCAR-8 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human OVCAR-8 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
OVCAR-8	IC₅₀	1.74 μM Compound: 5-Fluorouracil	Cytotoxicity against human OVCAR-8 cells assessed as cell growth inhibition Cytotoxicity against human OVCAR-8 cells assessed as cell growth inhibition	[PMID: 36470105]
OVCAR-8	IC₅₀	96.37 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human OVCAR8 cells after 72 hrs by proliferative assay Antiproliferative activity against p53 deficient human OVCAR8 cells after 72 hrs by proliferative assay	[PMID: 18469809]
OVCAR-8	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient OVCAR8 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient OVCAR8 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
Ovarian cancer cell line	IC₅₀	562.8 μM Compound: 5-FU	Anticancer activity against patient-derived human Ovarian tumor cells assessed as tumor growth inhibition incubated for 72 hrs by FMCA assay Anticancer activity against patient-derived human Ovarian tumor cells assessed as tumor growth inhibition incubated for 72 hrs by FMCA assay	[PMID: 36018000]
P388	ED₅₀	0.073 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 17067147]
P388	ED₅₀	0.075 μg/mL Compound: 5-FU	Growth inhibition of mouse P388 cells Growth inhibition of mouse P388 cells	[PMID: 12502333]
P388	ED₅₀	0.08 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 1812210]
P388	ED₅₀	3.72 μg/mL Compound: 5-fluorouracil	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 3443857]
P388	ED₅₀	6.2 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse P388 cells by Alamar blue assay Cytotoxicity against mouse P388 cells by Alamar blue assay	[PMID: 24128077]
P388	GI₅₀	0.073 μg/mL Compound: 5-FU	Growth inhibition of mouse P388 cells Growth inhibition of mouse P388 cells	[PMID: 16562827]
P388	IC₅₀	0.0219 mM Compound: 5-FU	Cytotoxicity against Mus musculus (mouse) P388 cells assessed as growth inhibition after 72 hr by MTT assay Cytotoxicity against Mus musculus (mouse) P388 cells assessed as growth inhibition after 72 hr by MTT assay	10.1007/s00044-012-0181-0
P388	IC₅₀	0.02 μg/mL Compound: 5-fluorouracil	Antitumor activity against mouse P388 cells Antitumor activity against mouse P388 cells	[PMID: 10579858]
P388	IC₅₀	0.49 μM Compound: 5-Fluorouracil	Concentration required to inhibit 50% of cell growth on murine P388 D1 cells. Concentration required to inhibit 50% of cell growth on murine P388 D1 cells.	[PMID: 11052798]
P388	IC₅₀	1.7 pM Compound: 5-FU	Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay Cytotoxicity against mouse P388 cells after 72 hrs by MTT assay	[PMID: 21640594]
P388	IC₅₀	5.8 μM Compound: 5-Fluorouracil	Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay Cytotoxicity against mouse P388 cells incubated for 72 hrs by alamar blue assay	[PMID: 28648460]
P388	IC₅₀	609 nM Compound: Fluorouracil	Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay Antiproliferative activity against mouse P388 cells after 48 hrs by MTT assay	[PMID: 2778449]
PA-1	IC₅₀	39.5 μM Compound: 5-FU	Cytotoxicity against human PA1 cells after 24 hrs by MTT assay Cytotoxicity against human PA1 cells after 24 hrs by MTT assay	[PMID: 23202484]
PA-1	IC₅₀	39.5 μM Compound: 5-FU	Growth inhibition of human PA1 cells after 24 hrs by MTT assay Growth inhibition of human PA1 cells after 24 hrs by MTT assay	[PMID: 28011220]
PA-1	IC₅₀	5 μM Compound: 5-FU	Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test	[PMID: 21530016]
PA-1	IC₅₀	7.59 μM Compound: 5-FU	Anticancer activity against human PA1 cells after 48 hrs by MTT assay Anticancer activity against human PA1 cells after 48 hrs by MTT assay	[PMID: 26413726]
PA-1	IC₅₀	8.51 μM Compound: F	Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human PA1 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
PANC-1	IC₅₀	0.22 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human pancreas epitheloid carcinoma (PANC-1) cells In vitro inhibitory activity against growth of Human pancreas epitheloid carcinoma (PANC-1) cells	[PMID: 1995901]
PANC-1	IC₅₀	0.4 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay Antiproliferative activity against human PANC1 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
PANC-1	IC₅₀	100 μM Compound: 5-Fluorouracil	Cytotoxicity against human PANC-1 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human PANC-1 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
PANC-1	IC₅₀	15 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human PANC1 cells incubated for 72 hrs by MTT assay	[PMID: 31829592]
PANC-1	IC₅₀	180.033 μM Compound: 5-Fu	Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 39163776]
PANC-1	IC₅₀	3.7 μM Compound: 5-fluorouracil	Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay Antiproliferative activity against human PANC1 cells after 72 hrs by WST8 assay	[PMID: 25919052]
PANC-1	IC₅₀	3.94 μM Compound: 5-FU	Cytotoxicity against human PANC1 cells by crystal violet staining Cytotoxicity against human PANC1 cells by crystal violet staining	[PMID: 20930123]
PANC-1	IC₅₀	4.3 μM Compound: 5-fluorouracil	Antiproliferative activity against human Panc-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay Antiproliferative activity against human Panc-1 cells assessed as reduction in cell growth incubated for 72 hrs by SRB assay	[PMID: 32007666]
PANC-1	IC₅₀	44.11 μM Compound: 5-FU	Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human PANC-1 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 39016216]
PANC-1	IC₅₀	47.83 μM Compound: 5-Fu	Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay	[PMID: 28110871]
PANC-1	IC₅₀	48.24 μM Compound: 5-Fu	Antiproliferative activity against human PANC-1 cells by CCK8 assay Antiproliferative activity against human PANC-1 cells by CCK8 assay	[PMID: 37939862]
PANC-1	IC₅₀	50 μM Compound: 5-FU	Cytotoxicity against human PANC1 cells assessed as inhibition of cell viability after 6 days by MTT assay Cytotoxicity against human PANC1 cells assessed as inhibition of cell viability after 6 days by MTT assay	[PMID: 23360104]
PANC-1	IC₅₀	50 μM Compound: 5-FU	Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay Cytotoxicity against human PANC1 cells after 72 hrs by MTT assay	[PMID: 25124114]
PANC-1	IC₅₀	54.1 μM Compound: 5-fluorouracil	Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human PANC1 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
PANC-1	IC₅₀	62.303 μM Compound: 5-Fluorouracil	Cytotoxicity against human PANC1 cells incubated for 24 hrs by MTT assay Cytotoxicity against human PANC1 cells incubated for 24 hrs by MTT assay	[PMID: 30904782]
PANC-1	IC₅₀	> 78 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of PANC-1 tumor cell line from pancreas. Compound was tested for its inhibitory effect on the growth of PANC-1 tumor cell line from pancreas.	10.1016/0960-894X(96)00339-3
PBMC	IC₅₀	> 40 μM Compound: 5-Fu	Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay Cytotoxicity against human PBMC assessed as reduction in cell growth after 72 hrs by MTT assay	[PMID: 31883693]
PBMC	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human PBMC assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
PBMC	IC₅₀	> 50 μM Compound: 5-Fu	Cytotoxicity against human PBMC cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human PBMC cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 31877536]
PC-14	IC₅₀	10 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of human lung squamous cell carcinoma PC14 solid cell lines. Concentration required for 50% inhibition of human lung squamous cell carcinoma PC14 solid cell lines.	[PMID: 1992123]
PC-14	IC₅₀	10 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human lung adenocarcinoma (PC-14) cell line. In vitro inhibitory activity against Human lung adenocarcinoma (PC-14) cell line.	[PMID: 1995905]
PC-3	GI₅₀	10.45 nM Compound: 5FU	Growth inhibition of human PC3 cells after 48 hrs by SRB assay Growth inhibition of human PC3 cells after 48 hrs by SRB assay	[PMID: 23094992]
PC-3	GI₅₀	11.7 μM Compound: 5-Fluorouracil	Growth inhibition of human PC3 cells after 48 hrs by SRB assay Growth inhibition of human PC3 cells after 48 hrs by SRB assay	[PMID: 28898082]
PC-3	GI₅₀	12 μM Compound: 5FU	Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
PC-3	GI₅₀	14.6 μM Compound: 5FU	Cytotoxicity against human PC3 cells after 48 hrs Cytotoxicity against human PC3 cells after 48 hrs	[PMID: 18798609]
PC-3	GI₅₀	2.36 μM Compound: 5-FU	Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
PC-3	GI₅₀	2.36 μM Compound: 5-FU	Anticancer activity against human PC-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human PC-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
PC-3	GI₅₀	21 μM Compound: 5-Fu	Growth inhibition of human PC3 cells after 48 hrs by SRB assay Growth inhibition of human PC3 cells after 48 hrs by SRB assay	[PMID: 22512908]
PC-3	GI₅₀	4.1 μM Compound: 5-FU	Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay Growth inhibition of human PC3 cells measured after 72 hrs by MTT assay	[PMID: 27504537]
PC-3	IC₅₀	0.016 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 19423198]
PC-3	IC₅₀	0.03 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 24 hrs by sulforhodamine B assay	[PMID: 27156770]
PC-3	IC₅₀	0.53 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29254641]
PC-3	IC₅₀	1.2 mM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27847140]
PC-3	IC₅₀	1.2 μM Compound: 5-FU	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 28431881]
PC-3	IC₅₀	1.2 μM Compound: 5-FU	Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay Cytotoxicity in human PC3 cells incubated for 48 hrs by MTT assay	[PMID: 28923381]
PC-3	IC₅₀	1.44 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26735909]
PC-3	IC₅₀	1.6 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 31546197]
PC-3	IC₅₀	1.6 μM Compound: 5-Fu	Cytotoxic activity against human PC3 cells Cytotoxic activity against human PC3 cells	[PMID: 28697923]
PC-3	IC₅₀	1.64 μM Compound: 5-FU	Anticancer activity against PTEN null human PC-3 cells assessed as inhibition of cell proliferation Anticancer activity against PTEN null human PC-3 cells assessed as inhibition of cell proliferation	[PMID: 32750679]
PC-3	IC₅₀	1.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition by MTT assay	[PMID: 27720296]
PC-3	IC₅₀	10.23 μM Compound: 5-fluorouracil	Inhibition of cell proliferation in human PC-3 cells incubated for 72 hrs by MTT assay Inhibition of cell proliferation in human PC-3 cells incubated for 72 hrs by MTT assay	[PMID: 39285177]
PC-3	IC₅₀	10.3 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human PC-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
PC-3	IC₅₀	10.36 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells Antiproliferative activity against human PC-3 cells	[PMID: 34655985]
PC-3	IC₅₀	10.4 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 34455358]
PC-3	IC₅₀	106.26 μM Compound: 2; 5-FU	Antiproliferative activity against human PC-3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells after 48 hrs by MTT assay	[PMID: 27322756]
PC-3	IC₅₀	12 μM Compound: 5-FU	Concentration required to inhibit proliferation of PC-3 prostate cancer cell lines Concentration required to inhibit proliferation of PC-3 prostate cancer cell lines	[PMID: 15341952]
PC-3	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity was evaluated against human prostate PC-3 cancer cell lines using the sulforhodamine B (STB) assay Antiproliferative activity was evaluated against human prostate PC-3 cancer cell lines using the sulforhodamine B (STB) assay	[PMID: 15454213]
PC-3	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity against prostate cancer PC-3 cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer PC-3 cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
PC-3	IC₅₀	12 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer PC-3 cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer PC-3 cell line by sulforhodamine B assay	[PMID: 16005217]
PC-3	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 24956552]
PC-3	IC₅₀	12 μM Compound: 5-fluorouracil	Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay Anticancer activity against human PC3 cells assessed as cell viability after 48 hrs by SRB assay	[PMID: 21074444]
PC-3	IC₅₀	12.23 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	10.1039/C6MD00061D
PC-3	IC₅₀	12.33 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29635165]
PC-3	IC₅₀	12.87 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 28763643]
PC-3	IC₅₀	13.3 μM Compound: 5 Fluorouracil	Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as decrease in cell viability after 24 hrs by MTT assay	[PMID: 27496212]
PC-3	IC₅₀	13.7 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
PC-3	IC₅₀	13.77 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human PC3 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
PC-3	IC₅₀	15.12 μM Compound: 5-Fu	Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36216031]
PC-3	IC₅₀	15.31 μM Compound: 5-Fu	Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxic activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 28011223]
PC-3	IC₅₀	15.69 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC3 after 48 hrs by MTT assay Cytotoxicity against human PC3 after 48 hrs by MTT assay	[PMID: 21486698]
PC-3	IC₅₀	17.31 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells measured after 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells measured after 48 hrs by MTT assay	[PMID: 32135407]
PC-3	IC₅₀	18.4 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 32682200]
PC-3	IC₅₀	18.42 μM Compound: 5-FU	Anticancer activity against human PC-3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human PC-3 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
PC-3	IC₅₀	19.87 μM Compound: 5-fluorouracil	Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 29133049]
PC-3	IC₅₀	2.1 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 22424614]
PC-3	IC₅₀	2.2 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
PC-3	IC₅₀	2.2 μM Compound: 5-FU	Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human PC3 cells after 48 hrs by sulforhodamine B assay	[PMID: 24910974]
PC-3	IC₅₀	2.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 48 hrs by sulphorhodamine B assay	[PMID: 26222449]
PC-3	IC₅₀	2.36 μM Compound: 5-Fluorouracil	Cytotoxicity against human PC-3 cells assessed as cell growth inhibition Cytotoxicity against human PC-3 cells assessed as cell growth inhibition	[PMID: 36470105]
PC-3	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
PC-3	IC₅₀	2.48 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 20800480]
PC-3	IC₅₀	2.5 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 36242987]
PC-3	IC₅₀	2.76 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 27092413]
PC-3	IC₅₀	2.88 μM Compound: 5-fluoro uracil	Cytotoxicity against human PC-3 cells incubated for 3 days by MTT assay Cytotoxicity against human PC-3 cells incubated for 3 days by MTT assay	[PMID: 33152379]
PC-3	IC₅₀	20.42 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay	[PMID: 31740251]
PC-3	IC₅₀	20.45 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
PC-3	IC₅₀	21.4 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human PC3 cells Cytotoxicity against human PC3 cells	[PMID: 31200236]
PC-3	IC₅₀	22.02 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells by MTT assay Antiproliferative activity against human PC3 cells by MTT assay	[PMID: 29131616]
PC-3	IC₅₀	22.63 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells after 48 hrs by MTT assay Cytotoxicity against human PC3 cells after 48 hrs by MTT assay	[PMID: 26363869]
PC-3	IC₅₀	23.1 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 30527868]
PC-3	IC₅₀	23.86 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29407983]
PC-3	IC₅₀	23.86 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29524728]
PC-3	IC₅₀	23.94 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
PC-3	IC₅₀	24.3 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 28494251]
PC-3	IC₅₀	24.33 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 28458133]
PC-3	IC₅₀	24.76 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 23792764]
PC-3	IC₅₀	24.76 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
PC-3	IC₅₀	27.07 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 23353743]
PC-3	IC₅₀	27.07 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells expressing SKP2 after 72 hrs by MTT assay	[PMID: 23735281]
PC-3	IC₅₀	27.61 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29407946]
PC-3	IC₅₀	27.64 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36336316]
PC-3	IC₅₀	29.3 μM Compound: 5-Fu	Antitumor activity against human PC3 cells after 72 hrs by MTT assay Antitumor activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 21486694]
PC-3	IC₅₀	29.31 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as inhibition of cell viability after 48 hrs by MTT assay	[PMID: 28038329]
PC-3	IC₅₀	30 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient PC3 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
PC-3	IC₅₀	31.44 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells expressing PCDNA after 72 hrs by MTT assay	[PMID: 23735281]
PC-3	IC₅₀	32.87 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability by MTT assay Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability by MTT assay	[PMID: 34715305]
PC-3	IC₅₀	35.75 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells by MTT assay Cytotoxicity against human PC3 cells by MTT assay	[PMID: 22801644]
PC-3	IC₅₀	38.61 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human PC3 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
PC-3	IC₅₀	4.68 μM Compound: 5-Fu	Cytotoxicity against human PC3 cells after 72 hrs by MTT assay Cytotoxicity against human PC3 cells after 72 hrs by MTT assay	[PMID: 24798098]
PC-3	IC₅₀	4.75 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 29133051]
PC-3	IC₅₀	4.9 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human PC3 cells assessed as cellular DNA content after 72 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
PC-3	IC₅₀	42.5 μM Compound: 5-FU	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 26595184]
PC-3	IC₅₀	42.5 μM Compound: 5-FU	Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay Cytotoxicity against human PC3 cells measured after 72 hrs by MTT assay	[PMID: 27537924]
PC-3	IC₅₀	45.32 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27614408]
PC-3	IC₅₀	46 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	10.1039/C5MD00382B
PC-3	IC₅₀	49.1 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 30737134]
PC-3	IC₅₀	5.32 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human PC3 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
PC-3	IC₅₀	57.04 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells measured after 48 hrs by MTT assay	[PMID: 27287368]
PC-3	IC₅₀	6.23 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 34302974]
PC-3	IC₅₀	6.27 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay	[PMID: 29475156]
PC-3	IC₅₀	6.7 μM Compound: 5-FU	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 37859725]
PC-3	IC₅₀	6.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 24 hrs Antiproliferative activity against human PC-3 cells assessed as reduction in cell viability measured for 24 hrs	[PMID: 31945642]
PC-3	IC₅₀	63.8 μM Compound: 5-fluorouracil	Cytotoxicity against human PC3 cells after 24 hrs by MTT assay Cytotoxicity against human PC3 cells after 24 hrs by MTT assay	[PMID: 31401008]
PC-3	IC₅₀	68.28 μM Compound: 5-FU	Anticancer activity against human PC3 cells after 48 hrs by MTT assay Anticancer activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 26413726]
PC-3	IC₅₀	72.07 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 27448774]
PC-3	IC₅₀	8.3 μg/mL Compound: 5-Fu	Cytotoxicity against human PC-3 cells Cytotoxicity against human PC-3 cells	[PMID: 31761383]
PC-3	IC₅₀	8.41 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 35259487]
PC-3	IC₅₀	8.41 μM Compound: 5-Fu	Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human PC-3 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 36931124]
PC-3	IC₅₀	8.45 μM Compound: 5-Fu	Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay Antiproliferative activity against human PC3 cells after 48 hrs by MTT assay	[PMID: 29958763]
PC-3	IC₅₀	8.46 μM Compound: 5-Fu	Antiproliferative activity against human PC-3 cells measured after 72 hrs by MTT assay Antiproliferative activity against human PC-3 cells measured after 72 hrs by MTT assay	[PMID: 37379957]
PC-3	IC₅₀	9.09 μM Compound: 5-FU	Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay Antiproliferative activity against human PC-3 cells assessed as inhibition of cell growth incubated for 96 hrs by MTT assay	[PMID: 35290844]
PC-3	IC₅₀	9.5 μM Compound: 5-fluorouracil	Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay Cytotoxicity against human PC-3 cells assessed as reduction in cell viability measured upto 72 hrs by MTT assay	[PMID: 33799070]
PC-3	IC₅₀	> 100 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against PC-3 cells Tested in vitro for anticancer activity against PC-3 cells	[PMID: 10072683]
PC-3	IC₅₀	> 30 μM Compound: 5-FU	Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay Cytotoxicity against human PC3 cells assessed as cell growth inhibition after 48 hrs by MTT assay	[PMID: 29133061]
PC-3M	IC₅₀	22.63 μM Compound: Fluorouracil	Cytotoxicity against human PC3M cells after 48 hrs by MTT assay Cytotoxicity against human PC3M cells after 48 hrs by MTT assay	[PMID: 22809558]
PC-8	IC₅₀	0.42 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human lung adenocarcinoma (PC-8) cells In vitro inhibitory activity against growth of Human lung adenocarcinoma (PC-8) cells	[PMID: 1995901]
PC-9	IC₅₀	1.99 μM Compound: 5-FU	Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay Cytotoxicity against human PC9 cells assessed as growth inhibition by MTT assay	[PMID: 27769034]
PC-9	IC₅₀	23.47 μM Compound: 5-FU	Cytotoxicity against human PC9 cells after 48 hrs by MTT assay Cytotoxicity against human PC9 cells after 48 hrs by MTT assay	[PMID: 22483608]
PC-9	IC₅₀	3.25 μM Compound: 5-Fu	Antiproliferative activity against human PC-9 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human PC-9 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 32682202]
PC-9	IC₅₀	4.12 μM Compound: 5-Fu	Antiproliferative activity against human PC9 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay Antiproliferative activity against human PC9 cells assessed as reduction in cell viability after 24 to 72 hrs by MTT assay	[PMID: 32619887]
PC-9	IC₅₀	6.52 μM Compound: 5-Fu	Antiproliferative activity against human PC-9 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human PC-9 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33385852]
PC-9	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human PC-9 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay Cytotoxicity against human PC-9 cells assessed as reduction in cell viability after 48 hrs by CCK8 assay	[PMID: 32659087]
PC10	IC₅₀	42 μg/mL Compound: 5-FU	Concentration at 50 percent inhibition of cell growth against human cancer PC10 cell line in vitro Concentration at 50 percent inhibition of cell growth against human cancer PC10 cell line in vitro	10.1016/S0960-894X(01)81041-6
PC10	IC₅₀	> 100 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of human lung squamous cell carcinoma PC10 solid cell lines. Concentration required for 50% inhibition of human lung squamous cell carcinoma PC10 solid cell lines.	[PMID: 1992123]
PC10	IC₅₀	> 100 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human lung squamous cell carcinoma (PC-10) cell line. In vitro inhibitory activity against Human lung squamous cell carcinoma (PC-10) cell line.	[PMID: 1995905]
PC10	IC₅₀	> 100 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of human lung squamous cell carcinoma cell lines (PC10). In vitro inhibitory effect on growth of human lung squamous cell carcinoma cell lines (PC10).	[PMID: 3373480]
PHA-Ly	IC₅₀	1.4 μg/mL Compound: 5-F-Ura	IIn vitro antitumor activity in PHA-Ly cell lines IIn vitro antitumor activity in PHA-Ly cell lines	[PMID: 8648611]
PLC	IC₅₀	116.8 μM Compound: 5-Fu	Antiproliferative activity against human PLC cells after 48 hrs by MTT assay Antiproliferative activity against human PLC cells after 48 hrs by MTT assay	[PMID: 30737134]
PLC-PRF-5	IC₅₀	2.8 μM Compound: Fluorouracil	Cytotoxicity against human PLC/PRF/5 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human PLC/PRF/5 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
PLC-PRF-5	IC₅₀	22.81 μM Compound: 2; 5-FU	Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human PLC/PRF/5 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
PLC-PRF-5	IC₅₀	35.66 μM Compound: 2; 5-FU	Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay Antiproliferative activity against human PLC/PRF/5 cells after 48 hrs by MTT assay	[PMID: 29202398]
PLC-PRF-5	IC₅₀	38.35 μM Compound: 2; 5-FU	Antiproliferative activity against human PLC-PRF-5 cells after 48 hrs by MTT assay Antiproliferative activity against human PLC-PRF-5 cells after 48 hrs by MTT assay	[PMID: 27322756]
PNT1A	IC₅₀	192.12 μM Compound: 5-FU	Antiproliferative activity against human PNT1A cells assessed as inhibition of cell growth measured after 48 hrs by Alamar blue dye based assay Antiproliferative activity against human PNT1A cells assessed as inhibition of cell growth measured after 48 hrs by Alamar blue dye based assay	[PMID: 38171252]
PNT1A	IC₅₀	9.7 μM Compound: 5-FU	Cytotoxicity against human PNT1A cells assessed as reduction in cell viability Cytotoxicity against human PNT1A cells assessed as reduction in cell viability	[PMID: 32750679]
PPC-1	IC₅₀	6.4 μM Compound: 5-FU	Concentration required to inhibit proliferation of PPC-1 prostate cancer cell lines Concentration required to inhibit proliferation of PPC-1 prostate cancer cell lines	[PMID: 15341952]
PPC-1	IC₅₀	6.4 μM Compound: 5-FU	Antiproliferative activity against prostate cancer PPC-1 cell line using sulforhodamine B(SRB) assay Antiproliferative activity against prostate cancer PPC-1 cell line using sulforhodamine B(SRB) assay	[PMID: 15801848]
PPC-1	IC₅₀	6.4 μM Compound: 5-FU	Antiproliferative activity against human prostate cancer PPC-1 cell line by sulforhodamine B assay Antiproliferative activity against human prostate cancer PPC-1 cell line by sulforhodamine B assay	[PMID: 16005217]
PSN1	IC₅₀	4.4 μM Compound: 5-fluorouracil	Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay Antiproliferative activity against human PSN1 cells after 72 hrs by WST8 assay	[PMID: 25919052]
PSN1	IC₅₀	8.7 μM Compound: 5-Fluorouracil	Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay Antiproliferative activity against human PSN1 cells after 72 hrs by WST-8 assay	[PMID: 26606140]
PaTu 8988t	IC₅₀	2.08 μM Compound: 5-FU	Cytotoxicity against human Patu-T cells by crystal violet staining Cytotoxicity against human Patu-T cells by crystal violet staining	[PMID: 20930123]
PaTu 8988t	IC₅₀	33.2 μM Compound: 5-FU	Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining Cytotoxicity against human 5-FU-resistant Patu-T cells by crystal violet staining	[PMID: 20930123]
Panel NCI-60 (60 carcinoma cell lines)	GI₅₀	18000 μM Compound: 5-fluorouracil	Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) incubated for 48 hrs by sulforhodamine B assay Growth inhibition of human Panel NCI-60 (60 carcinoma cell lines) incubated for 48 hrs by sulforhodamine B assay	[PMID: 33766762]
Panel NCI-60 (60 carcinoma cell lines)	GI₅₀	22.6 μM Compound: 5-Fluorouracil	Anticancer activity against human Panel NCI-60 (60 carcinoma cell lines) cells assessed as cell growth inhibition incubated for 48 hrs by sulforhodamine B assay Anticancer activity against human Panel NCI-60 (60 carcinoma cell lines) cells assessed as cell growth inhibition incubated for 48 hrs by sulforhodamine B assay	[PMID: 31881454]
QG-56	IC₅₀	0.18 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human lung squamous-cell carcinoma (QG-56) cells In vitro inhibitory activity against growth of Human lung squamous-cell carcinoma (QG-56) cells	[PMID: 1995901]
QG-90	IC₅₀	0.22 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human lung small cell carcinoma (QG-90) cells In vitro inhibitory activity against growth of Human lung small cell carcinoma (QG-90) cells	[PMID: 1995901]
QGY-7703	IC₅₀	14.2 μM Compound: 5-Fu	Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay Antiproliferative activity against human QGY7703 cells after 24 hrs by CCK-8 assay	[PMID: 29499490]
QGY-7703	IC₅₀	15.66 μM Compound: 5-Fu	Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay Cytotoxicity against human QGY7703 cells after 48 hrs by CCK-8 assay	[PMID: 24013415]
RKO	IC₅₀	10.09 μM Compound: 5-FU	Antitumor activity against human RKO cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human RKO cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
RKO	IC₅₀	10.2 μM Compound: 5-FU	Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay Growth inhibition of human RKO cells after 48 hrs by CCK-8 assay	[PMID: 30106289]
RKO	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human RKO cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay Cytotoxicity against human RKO cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay	[PMID: 37243616]
RKO	IC₅₀	12.71 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
RKO	IC₅₀	2.9 μM Compound: 5-FU	Antiproliferative activity against human RKO cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human RKO cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
RKO	IC₅₀	3.43 μM Compound: 5-Fu	Cytotoxicity against human RKO cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human RKO cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
RKO	IC₅₀	3.96 μM Compound: 5-FU	Cytotoxicity against human RKO cells incubated for 72 hrs by MTS assay Cytotoxicity against human RKO cells incubated for 72 hrs by MTS assay	[PMID: 38843656]
RKO	IC₅₀	4.39 μM Compound: 5-Fu	Cytotoxicity against human RKO cells after 3 days by SRB assay Cytotoxicity against human RKO cells after 3 days by SRB assay	[PMID: 24704691]
RKO	IC₅₀	41.1 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26922233]
RKO	IC₅₀	6.8 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell growth after 72 hrs by MTT assay	[PMID: 26922233]
RKO	IC₅₀	> 10 μM Compound: 5-FU	Cytotoxicity against human RKO cells after 24 hrs by MTT assay Cytotoxicity against human RKO cells after 24 hrs by MTT assay	[PMID: 32223193]
RKO	IC₅₀	> 50 μM Compound: 5-FU	Anticancer activity against human RKO cells assessed as inhibition of cell growth after 24 hrs by MTT assay Anticancer activity against human RKO cells assessed as inhibition of cell growth after 24 hrs by MTT assay	[PMID: 26922233]
RL	IC₅₀	3.2 μM Compound: 5-FU	Antiproliferative activity against human RL cells after 72 hrs by MTT assay Antiproliferative activity against human RL cells after 72 hrs by MTT assay	[PMID: 19743863]
RPMI-8226	GI₅₀	0.04 μM Compound: 5-FU	Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human RPMI8226 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
RPMI-8226	GI₅₀	0.04 μM Compound: 5-FU	Anticancer activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human RPMI-8226 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
RPMI-8226	IC₅₀	0.04 μM Compound: 5-Fluorouracil	Cytotoxicity against human RPMI-8226 cells assessed as cell growth inhibition Cytotoxicity against human RPMI-8226 cells assessed as cell growth inhibition	[PMID: 36470105]
RPMI-8226	IC₅₀	0.07 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human myeloma (RPMI 8226) cells In vitro inhibitory activity against growth of Human myeloma (RPMI 8226) cells	[PMID: 1995901]
RPMI-8226	IC₅₀	3.55 μM Compound: 5-Fluorouracil	Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human RPMI8226 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
RPMI-8226	IC₅₀	3.55 μM Compound: 5-fluorouracil	Cytotoxicity against human RPMI8226 cells Cytotoxicity against human RPMI8226 cells	[PMID: 16996657]
RT-112	IC₅₀	7.4 μM Compound: 5-FU	Antiproliferative activity against human RT-112 cells Antiproliferative activity against human RT-112 cells	[PMID: 34655985]
RXF 393	GI₅₀	2.61 μM Compound: 5-FU	Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human RXF393 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
RXF 393	GI₅₀	2.61 μM Compound: 5-FU	Anticancer activity against human RXF 393 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human RXF 393 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
RXF 393	IC₅₀	2.61 μM Compound: 5-Fluorouracil	Cytotoxicity against human RXF 393 cells assessed as cell growth inhibition Cytotoxicity against human RXF 393 cells assessed as cell growth inhibition	[PMID: 36470105]
RXF 393	IC₅₀	28.23 μM Compound: 5-FU	Cytotoxicity against human RXF 393 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay Cytotoxicity against human RXF 393 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay	[PMID: 35182815]
SAOS-2	IC₅₀	0.78 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human osteogenic sarcoma (Saos-2) cells In vitro inhibitory activity against growth of Human osteogenic sarcoma (Saos-2) cells	[PMID: 1995901]
SCC-9	IC₅₀	12.7 μg/mL Compound: 5-FU	Antiproliferative activity against human SCC-9 cells assessed as cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human SCC-9 cells assessed as cell viability measured after 72 hrs by MTT assay	[PMID: 34463097]
SCLC	IC₅₀	8.4 μM Compound: 5-FluoroUracil	Cytotoxicity against human SCLC cells resistant to cisplatin (SCLC/CDDP) Cytotoxicity against human SCLC cells resistant to cisplatin (SCLC/CDDP)	[PMID: 8258835]
SF-268	GI₅₀	1.62 μM Compound: 5-FU	Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF268 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SF-268	GI₅₀	1.62 μM Compound: 5-FU	Anticancer activity against human SF-268 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SF-268 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SF-268	GI₅₀	49.21 μM Compound: 5-FU	Cytotoxicity against human SF268 cells after 48 hrs by SRB assay Cytotoxicity against human SF268 cells after 48 hrs by SRB assay	10.1007/s00044-013-0798-7
SF-268	IC₅₀	1.62 μM Compound: 5-Fluorouracil	Cytotoxicity against human SF-268 cells assessed as cell growth inhibition Cytotoxicity against human SF-268 cells assessed as cell growth inhibition	[PMID: 36470105]
SF-268	IC₅₀	87.96 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human SF268 cells after 72 hrs Antiproliferative activity against p53 deficient human SF268 cells after 72 hrs	[PMID: 18469809]
SF-268	IC₅₀	> 100 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient SF268 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient SF268 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
SF-295	GI₅₀	0.22 μM Compound: 5-FU	Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF295 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SF-295	GI₅₀	76 μM Compound: 5-Fu	Growth inhibition of human SF295 cells after 48 hrs by SRB assay Growth inhibition of human SF295 cells after 48 hrs by SRB assay	[PMID: 22512908]
SF-295	IC₅₀	0.49 μM Compound: 5-FU	Antiproliferative activity against human SF-295 cells assessed as cell growth inhibition in presence of piperlongumine Antiproliferative activity against human SF-295 cells assessed as cell growth inhibition in presence of piperlongumine	[PMID: 33930801]
SF-295	IC₅₀	2.33 μM Compound: 5-FU	Antiproliferative activity against human SF-295 cells assessed as cell growth inhibition Antiproliferative activity against human SF-295 cells assessed as cell growth inhibition	[PMID: 33930801]
SF-539	GI₅₀	0.06 μM Compound: 5-FU	Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SF539 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SF-539	GI₅₀	0.06 μM Compound: 5-FU	Anticancer activity against human SF-539 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SF-539 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SF-539	IC₅₀	0.06 μM Compound: 5-Fluorouracil	Cytotoxicity against human SF-539 cells assessed as cell growth inhibition Cytotoxicity against human SF-539 cells assessed as cell growth inhibition	[PMID: 36470105]
SF-539	IC₅₀	43 μM Compound: 5-FU	Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human SF539 cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
SF-539	IC₅₀	50.09 μM Compound: 5-FU	Antiproliferative activity against human SF539 cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human SF539 cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
SGC-7901	EC₅₀	7.03 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 26883149]
SGC-7901	IC₅₀	0.58 μg/mL Compound: 5-FU	Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay	10.1007/s00044-009-9193-9
SGC-7901	IC₅₀	0.86 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability incubated for 72 hrs by SRB assay	10.1039/C4MD00209A
SGC-7901	IC₅₀	10.98 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 29133051]
SGC-7901	IC₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 26595184]
SGC-7901	IC₅₀	11.9 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells measured after 72 hrs by MTT assay	[PMID: 27537924]
SGC-7901	IC₅₀	11.96 μM Compound: 5-FU	Cytotoxicity against human SGC7901 assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human SGC7901 assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 30709651]
SGC-7901	IC₅₀	12 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 6 days by MTT assay Cytotoxicity against human SGC7901 cells after 6 days by MTT assay	[PMID: 29786436]
SGC-7901	IC₅₀	13.1 μM Compound: 5-Fu	Cytotoxicity against human SGC-7901 cells assessed as cell inhibition measured after 72 hrs by MTT assay Cytotoxicity against human SGC-7901 cells assessed as cell inhibition measured after 72 hrs by MTT assay	[PMID: 36774698]
SGC-7901	IC₅₀	13.25 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells incubated for 48 to 72 hrs by MTT assay	[PMID: 28395218]
SGC-7901	IC₅₀	14.49 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 22687745]
SGC-7901	IC₅₀	16.03 μg/mL Compound: 5-fluorouracil	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 28988624]
SGC-7901	IC₅₀	19.84 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 29635169]
SGC-7901	IC₅₀	2.19 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay Cytotoxicity against Homo sapiens (human) SGC7901 cells by MTT assay	10.1007/s00044-010-9395-1
SGC-7901	IC₅₀	2.95 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 20494492]
SGC-7901	IC₅₀	2.96 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells incubated for 72 hrs by MTT assay	[PMID: 31404863]
SGC-7901	IC₅₀	21 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human SGC7901 cells assessed as reduction in cell viability by MTT assay	[PMID: 31029946]
SGC-7901	IC₅₀	26.3 μM Compound: 5-fluorouracil	Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 36893627]
SGC-7901	IC₅₀	28.5 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 23279864]
SGC-7901	IC₅₀	28.9 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 23490159]
SGC-7901	IC₅₀	29.19 μM Compound: 5-Fu	Cytotoxicity against Homo sapiens (human) SGC7901 cells after 72 hr by MTT assay Cytotoxicity against Homo sapiens (human) SGC7901 cells after 72 hr by MTT assay	10.1007/s00044-011-9549-9
SGC-7901	IC₅₀	31.46 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 after 48 hrs by MTT assay Cytotoxicity against human SGC7901 after 48 hrs by MTT assay	[PMID: 21486698]
SGC-7901	IC₅₀	34.4 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 29232583]
SGC-7901	IC₅₀	36.4 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 30108895]
SGC-7901	IC₅₀	46.35 μM Compound: 5-Fluorouracil	Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay Anticancer activity against human SGC7901 cells assessed as cell survival measured after 48 hrs by MTT assay	[PMID: 23312949]
SGC-7901	IC₅₀	5.54 μM Compound: 5-FU	Anticancer activity against human SGC-7901 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Anticancer activity against human SGC-7901 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 31577977]
SGC-7901	IC₅₀	53.58 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 30826506]
SGC-7901	IC₅₀	53.58 μM Compound: 5-FU	Cytotoxicity against human SGC-7901 cells by MTT assay Cytotoxicity against human SGC-7901 cells by MTT assay	[PMID: 33831559]
SGC-7901	IC₅₀	56.12 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 27503679]
SGC-7901	IC₅₀	59.9 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 25164762]
SGC-7901	IC₅₀	6.04 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells by after 48 hrs by MTT assay	[PMID: 22579780]
SGC-7901	IC₅₀	6.04 μM Compound: 5-Fu	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 23920246]
SGC-7901	IC₅₀	6.12 μM Compound: 5-Fluorouracil	Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human SGC7901 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
SGC-7901	IC₅₀	6.3 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 22727445]
SGC-7901	IC₅₀	6.38 μM Compound: 5-Fu	Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 31202992]
SGC-7901	IC₅₀	6.46 μM Compound: 5-FU	Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 30921757]
SGC-7901	IC₅₀	6.56 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 25554922]
SGC-7901	IC₅₀	6.8 μM Compound: 5-fluorouracil	Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability measured for 24 hrs Antiproliferative activity against human SGC-7901 cells assessed as reduction in cell viability measured for 24 hrs	[PMID: 31945642]
SGC-7901	IC₅₀	69.81 μM Compound: 5-Fu	Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human SGC-7901 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 34628244]
SGC-7901	IC₅₀	7.11 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 22405648]
SGC-7901	IC₅₀	7.36 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay Antiproliferative activity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 20947362]
SGC-7901	IC₅₀	7.37 μM Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 24119869]
SGC-7901	IC₅₀	7.38 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 after 48 hrs by MTT assay Cytotoxicity against human SGC7901 after 48 hrs by MTT assay	[PMID: 20538457]
SGC-7901	IC₅₀	7.38 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 48 hrs by MTT assay	[PMID: 20800480]
SGC-7901	IC₅₀	76 μM Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 2 days by alamar blue assay Cytotoxicity against human SGC7901 cells after 2 days by alamar blue assay	[PMID: 22093761]
SGC-7901	IC₅₀	8.7 μg/mL Compound: 5-FU	Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay Cytotoxicity against human SGC7901 cells after 72 hrs by MTT assay	[PMID: 22647218]
SGC-7901	IC₅₀	> 30 μM Compound: 5-FU	Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Antiproliferative activity against human SGC-7901 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 33248852]
SH-SY5Y	GI₅₀	1.5 μM Compound: 5-FU	Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control Antiproliferative activity against human SH-SY5Y cells after 72 hrs by MTT-based Mosmann assay relative to control	[PMID: 26539626]
SH-SY5Y	GI₅₀	11.9 μM Compound: 5-FU	Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay	[PMID: 29040954]
SH-SY5Y	GI₅₀	12 μM Compound: 5-Fu	Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells after 48 hrs by MTT assay	[PMID: 28763647]
SH-SY5Y	IC₅₀	0.97 μM Compound: 5-Fu	Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay	[PMID: 23685571]
SH-SY5Y	IC₅₀	1.09 μM Compound: 5-Fu	Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay Cytotoxicity against human SH-SY5Y cells after 72 hrs by MTT assay	[PMID: 22687745]
SH-SY5Y	IC₅₀	3.26 μM Compound: 5-Fu	Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human SH-SY5Y cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
SK-BR-3	GI₅₀	3 μM Compound: 5-fluorouracil	Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay Antiproliferative activity against estrogen receptor deficient human SKBR3 cells after 48 hrs by SRB assay	[PMID: 20438092]
SK-BR-3	IC₅₀	10 μM Compound: 5-Fluorouracil	Cytotoxicity against human SKBR3 cells Cytotoxicity against human SKBR3 cells	[PMID: 31200236]
SK-BR-3	IC₅₀	38.25 μM Compound: 5-FU	Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay Antiproliferative activity against human SKBR3 cells after 72 hrs by MTT assay	[PMID: 21524829]
SK-BR-3	IC₅₀	38.88 μM Compound: 5-FU	Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay Cytotoxicity against human SKBR3 cells overexpressing HER2 assessed as cell growth inhibition after 48 hrs by WST-1 assay	[PMID: 25466196]
SK-BR-3	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity in human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21250700]
SK-BR-3	IC₅₀	> 20 μM Compound: 5-fluorouracil	Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human SK-BR-3 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 21381696]
SK-HEP1	GI₅₀	6.3 μM Compound: 5-Fu	Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay	[PMID: 22512908]
SK-HEP1	GI₅₀	7.6 nM Compound: 5FU	Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay Growth inhibition of human SKHEP1 cells after 48 hrs by SRB assay	[PMID: 23094992]
SK-HEP1	IC₅₀	12.5 μM Compound: 5-FU	Anticancer activity against human SK-HEP1 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human SK-HEP1 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
SK-HEP1	IC₅₀	4.95 μM Compound: 5-Fu	Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
SK-HEP1	IC₅₀	> 40 μM Compound: 5-FU	Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay Antiproliferative activity against human SK-HEP1 cells assessed as inhibition of cell growth measured after 72 hrs by MTT assay	[PMID: 37182331]
SK-MEL	IC₅₀	6.3 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human SK-MEL cells after 2 to 7 days by neutral red assay Cytotoxicity against human SK-MEL cells after 2 to 7 days by neutral red assay	[PMID: 11374943]
SK-MEL-2	GI₅₀	56.7 μM Compound: 5-FU	Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SK-MEL-2 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-MEL-2	GI₅₀	56.7 μM Compound: 5-FU	Anticancer activity against human SK-MEL-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-MEL-2 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-MEL-2	IC₅₀	0.63 μg/mL Compound: 5-FU	Inhibitory concentration of compound for cytotoxicity against SK-MEL-2 human melanoma cells was determined Inhibitory concentration of compound for cytotoxicity against SK-MEL-2 human melanoma cells was determined	[PMID: 11814824]
SK-MEL-2	IC₅₀	56.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human SK-MEL-2 cells assessed as cell growth inhibition Cytotoxicity against human SK-MEL-2 cells assessed as cell growth inhibition	[PMID: 36470105]
SK-MEL-2	IC₅₀	6.52 μM Compound: 5-Fu	Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay Antiproliferative activity against human SK-MEL-2 cells assessed as inhibition of cell growth measured after 72 hrs by CCK8 assay	[PMID: 35797896]
SK-MEL-28	GI₅₀	1.03 μM Compound: 5-FU	Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SK-MEL-28 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-MEL-28	GI₅₀	1.03 μM Compound: 5-FU	Anticancer activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-MEL-28	IC₅₀	0.1 μg/mL Compound: 5-fluorouracil	Antitumor activity against human SK MEL28 cells Antitumor activity against human SK MEL28 cells	[PMID: 10579858]
SK-MEL-28	IC₅₀	1.03 μM Compound: 5-Fluorouracil	Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition	[PMID: 36470105]
SK-MEL-28	IC₅₀	10.23 μM Compound: 5-FU	Antiproliferative activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Antiproliferative activity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 38107169]
SK-MEL-28	IC₅₀	10.7 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human melanoma (P-36) cell line. In vitro inhibitory activity against Human melanoma (P-36) cell line.	[PMID: 1995905]
SK-MEL-28	IC₅₀	11 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human melanoma cell line P36 after 72 hr of incubation The compound was evaluated for antitumoral activity against human melanoma cell line P36 after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
SK-MEL-28	IC₅₀	14.64 μM Compound: 5-FU	Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay Cytotoxicity against human SK-MEL-28 cells assessed as cell growth inhibition incubated for 48 hrs by MTT assay	[PMID: 35635947]
SK-MEL-28	IC₅₀	4.5 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against SK-MEL-28 cells Tested in vitro for anticancer activity against SK-MEL-28 cells	[PMID: 10072683]
SK-MEL-5	GI₅₀	0.46 μM Compound: 5-FU	Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SK-MEL-5 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-MEL-5	GI₅₀	0.46 μM Compound: 5-FU	Anticancer activity against human SK-MEL-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-MEL-5 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-MEL-5	IC₅₀	0.46 μM Compound: 5-Fluorouracil	Cytotoxicity against human SK-MEL-5 cells assessed as cell growth inhibition Cytotoxicity against human SK-MEL-5 cells assessed as cell growth inhibition	[PMID: 36470105]
SK-MEL-5	IC₅₀	15.31 μM Compound: 5-FU	Cytotoxicity against human SK-MEL-5 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay Cytotoxicity against human SK-MEL-5 cells assessed as inhibition of cell viability incubated for 72 hrs under hypoxia condition by MTT assay	[PMID: 35182815]
SK-MES-1	IC₅₀	0.31 μM Compound: 5-fluorouracil	Antitumor activity against lung carcinoma cell line (SK-MES-1) Antitumor activity against lung carcinoma cell line (SK-MES-1)	[PMID: 2547068]
SK-MES-1	IC₅₀	13.1 μM Compound: 5-fluorouracil	Tested in vitro for anticancer activity against SK-MES-1 cells Tested in vitro for anticancer activity against SK-MES-1 cells	[PMID: 10072683]
SK-N-SH	IC₅₀	10.32 μM Compound: 5-Fu	Antiproliferative activity against human SK-N-SH cells after 72 hrs by MTT assay Antiproliferative activity against human SK-N-SH cells after 72 hrs by MTT assay	10.1039/C6MD00169F
SK-N-SH	IC₅₀	7.22 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SK-N-SH cells by MTT assay Antiproliferative activity against human SK-N-SH cells by MTT assay	[PMID: 31546197]
SK-N-SH	IC₅₀	9.84 μM Compound: 5-FU	Cytotoxicity against human SK-N-SH cells assessed as cell growth inhibition after 72 hrs by MTT assay Cytotoxicity against human SK-N-SH cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27423479]
SK-OV-3	GI₅₀	21.8 μM Compound: 5-FU	Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SKOV3 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SK-OV-3	GI₅₀	21.8 μM Compound: 5-FU	Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SK-OV-3 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SK-OV-3	IC₅₀	0.03 μg/mL Compound: 5-FU	Inhibitory concentration of compound for cytotoxicity against SK-OV-3 human ovarian cells was determined Inhibitory concentration of compound for cytotoxicity against SK-OV-3 human ovarian cells was determined	[PMID: 11814824]
SK-OV-3	IC₅₀	10.85 μM Compound: 5-Fu	Cytotoxicity against human SK-OV-3 cells assessed as cell viability measured after 48 hrs by MTT assay Cytotoxicity against human SK-OV-3 cells assessed as cell viability measured after 48 hrs by MTT assay	[PMID: 38964974]
SK-OV-3	IC₅₀	20.8 μM Compound: 5-Fu	Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 28759877]
SK-OV-3	IC₅₀	21.6 μM Compound: 5-Fu	Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human SK-OV-3 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
SK-OV-3	IC₅₀	21.8 μM Compound: 5-Fluorouracil	Cytotoxicity against human SK-OV-3 cells assessed as cell growth inhibition Cytotoxicity against human SK-OV-3 cells assessed as cell growth inhibition	[PMID: 36470105]
SK-OV-3	IC₅₀	22.43 μM Compound: 5-FU	Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay Cytotoxic activity against human SKOV3 cells assessed as inhibition of cell growth after 48 hrs by MTT assay	[PMID: 26706349]
SK-OV-3	IC₅₀	23.11 μM Compound: 5-Fu	Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxic activity against human SKOV3 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 28011223]
SK-OV-3	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 23988357]
SK-OV-3	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 3 days by MTT assay Cytotoxicity against human SKOV3 cells after 3 days by MTT assay	[PMID: 24095745]
SK-OV-3	IC₅₀	24.43 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 24565905]
SK-OV-3	IC₅₀	25 μM Compound: 5-FU	Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Antiproliferative activity against human SK-OV-3 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 37859725]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 30092368]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 30108826]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Antiproliferative activity against human SK-OV-3 cells by MTT assay Antiproliferative activity against human SK-OV-3 cells by MTT assay	[PMID: 33109400]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Antiproliferative activity against human SK-OV-3 cells Antiproliferative activity against human SK-OV-3 cells	[PMID: 34655985]
SK-OV-3	IC₅₀	26.34 μM Compound: 5-FU	Antiproliferative activity against human SK-OV-3 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human SK-OV-3 cells incubated for 48 hrs by MTT assay	[PMID: 37972528]
SK-OV-3	IC₅₀	27.34 μM Compound: 5-Fu	Cytotoxicity against human SKOV3 cells after 2 days by MTT assay Cytotoxicity against human SKOV3 cells after 2 days by MTT assay	[PMID: 25841196]
SK-OV-3	IC₅₀	32.5 μM Compound: 5-FU	Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay Antiproliferative activity against human SKOV3 cells after 48 hrs by MTT assay	[PMID: 28756264]
SK-OV-3	IC₅₀	47.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human SK-OV-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human SK-OV-3 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
SK-OV-3	IC₅₀	> 10 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human SKOV3 cells after 2 to 7 days by neutral red assay Cytotoxicity against human SKOV3 cells after 2 to 7 days by neutral red assay	[PMID: 11374943]
SMMC-7721	IC₅₀	1.59 μM Compound: 5-Fu	Antiproliferative activity against human SMMC-7721 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay Antiproliferative activity against human SMMC-7721 cells assessed as inhibition of cell proliferation incubated for 48 hrs by MTT assay	[PMID: 37360398]
SMMC-7721	IC₅₀	12.47 μM Compound: 5-Fu	Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay Antiproliferative activity against human SMMC7721 cells after 24 hrs by CCK-8 assay	[PMID: 29499490]
SMMC-7721	IC₅₀	13 μM Compound: fluorouracil	Cytotoxicity against human SMMC7721 cells Cytotoxicity against human SMMC7721 cells	[PMID: 21495659]
SMMC-7721	IC₅₀	13.7 μM Compound: 5-Fu	Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 29475156]
SMMC-7721	IC₅₀	14.2 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability after 72 hrs by MTT assay	10.1039/C5MD00240K
SMMC-7721	IC₅₀	14.55 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay Cytotoxicity against human SMMC7721 cells after 48 hrs by CCK-8 assay	[PMID: 24013415]
SMMC-7721	IC₅₀	15 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells Cytotoxicity against human SMMC7721 cells	[PMID: 22283451]
SMMC-7721	IC₅₀	15.32 μM Compound: 5-FU	Antiproliferative activity against human SMMC-7721 cells by MTT assay Antiproliferative activity against human SMMC-7721 cells by MTT assay	[PMID: 33109400]
SMMC-7721	IC₅₀	19.25 μg/mL Compound: 5-fluorouracil	Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 28988624]
SMMC-7721	IC₅₀	2.3 x 10^-2 μg/mL Compound: fluorouracil	Cytotoxicity against human SMMC7721 cells by MTT assay Cytotoxicity against human SMMC7721 cells by MTT assay	[PMID: 22011319]
SMMC-7721	IC₅₀	2.5 μM Compound: Fluorouracil	Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability by MTT assay Cytotoxicity against human SMMC7721 cells assessed as reduction in cell viability by MTT assay	[PMID: 31013087]
SMMC-7721	IC₅₀	20 μM Compound: 5-FU	Antiproliferative activity against human SMMC-7721 cells measured after 48 hrs Antiproliferative activity against human SMMC-7721 cells measured after 48 hrs	[PMID: 34128674]
SMMC-7721	IC₅₀	20.4 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 25707012]
SMMC-7721	IC₅₀	26.71 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 23644193]
SMMC-7721	IC₅₀	37.8 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 29232583]
SMMC-7721	IC₅₀	37.8 μM Compound: 5-FU	Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human SMMC-7721 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30739827]
SMMC-7721	IC₅₀	4.87 μM Compound: 5-Fluorouracil	Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay Anticancer activity against human SMMC7721 cells assessed as cell survival after 48 hrs by MTT assay	[PMID: 25812966]
SMMC-7721	IC₅₀	5.62 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay Antiproliferative activity against human SMMC7721 cells assessed as inhibition of cell proliferation by CCK8 assay	[PMID: 25442303]
SMMC-7721	IC₅₀	5.62 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK-8 assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK-8 assay	[PMID: 27542307]
SMMC-7721	IC₅₀	5.62 μM Compound: 5-Fu	Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by CCK8 assay	[PMID: 26786698]
SMMC-7721	IC₅₀	51 μM Compound: 5-FU	Cytotoxicity against SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against SMMC7721 cells after 48 hrs by MTT assay	[PMID: 17604394]
SMMC-7721	IC₅₀	67.7 μM Compound: 5-FU	Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay Antiproliferative activity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 25164762]
SMMC-7721	IC₅₀	9.7 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SMMC-7721 cells Antiproliferative activity against human SMMC-7721 cells	[PMID: 33421712]
SMMC-7721	IC₅₀	9.78 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 72 hrs by MTT assay	[PMID: 23792764]
SMMC-7721	IC₅₀	9.78 μM Compound: 5-Fu	Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human SMMC7721 cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 24077182]
SMMC-7721	IC₅₀	> 100 μM Compound: 5-fluorouracil	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay	[PMID: 22537362]
SN12C	GI₅₀	0.49 μM Compound: 5-FU	Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SN12C cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SN12C	GI₅₀	0.49 μM Compound: 5-FU	Anticancer activity against human SN12C cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SN12C cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SN12C	IC₅₀	0.49 μM Compound: 5-Fluorouracil	Cytotoxicity against human SN12C cells assessed as cell growth inhibition Cytotoxicity against human SN12C cells assessed as cell growth inhibition	[PMID: 36470105]
SN12C	IC₅₀	6.5 μg/mL Compound: 5-Fu	Cytotoxicity against human SN12C cells assessed as decrease in cell viability after 96 hrs Cytotoxicity against human SN12C cells assessed as decrease in cell viability after 96 hrs	[PMID: 29673982]
SNB-19	GI₅₀	3.81 μM Compound: 5-FU	Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SNB19 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SNB-19	GI₅₀	3.81 μM Compound: 5-FU	Anticancer activity against human SNB-19 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SNB-19 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SNB-19	IC₅₀	3.81 μM Compound: 5-Fluorouracil	Cytotoxicity against human SNB-19 cells assessed as cell growth inhibition Cytotoxicity against human SNB-19 cells assessed as cell growth inhibition	[PMID: 36470105]
SNB-75	GI₅₀	78.7 μM Compound: 5-FU	Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SNB75 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SNB-75	GI₅₀	78.7 μM Compound: 5-FU	Anticancer activity against human SNB-75 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SNB-75 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SNB-75	IC₅₀	78.7 μM Compound: 5-Fluorouracil	Cytotoxicity against human SNB-75 cells assessed as cell growth inhibition Cytotoxicity against human SNB-75 cells assessed as cell growth inhibition	[PMID: 36470105]
SNU-16	EC₅₀	6.4 μM Compound: 5FU	Cytotoxicity against human SNU-16 cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay Cytotoxicity against human SNU-16 cells assessed as inhibition of proliferation measured after 24 to 72 hrs by CCK-8 assay	[PMID: 35939803]
SNU-423	IC₅₀	7.4 μM Compound: 5-FU	Antiproliferative activity against human SNU-423 cells Antiproliferative activity against human SNU-423 cells	[PMID: 34655985]
SNU-C2A	IC₅₀	2.7 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of SUN-C2A tumor cell line from colon. Compound was tested for its inhibitory effect on the growth of SUN-C2A tumor cell line from colon.	10.1016/0960-894X(96)00339-3
SR	GI₅₀	0.02 μM Compound: 5-FU	Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SR cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SR	GI₅₀	0.0238 μM Compound: 5-FU	Cytotoxicity against human SR cells after 48 hrs by SRB assay Cytotoxicity against human SR cells after 48 hrs by SRB assay	[PMID: 22305543]
SR	IC₅₀	60.3 μM Compound: 5-Fluorouracil	Antileukemic activity against human SR cells assessed as inhibition of tumor growth after 24 hrs Antileukemic activity against human SR cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
SR	IC₅₀	60.3 μM Compound: 5-fluorouracil	Cytotoxicity against human SR cells Cytotoxicity against human SR cells	[PMID: 16996657]
SR	IC₅₀	7.38 μM Compound: 5-FU	Antiproliferative activity against human SR cells assessed as inhibition of cell growth incubated for 2 to 4 hrs by MTT assay Antiproliferative activity against human SR cells assessed as inhibition of cell growth incubated for 2 to 4 hrs by MTT assay	[PMID: 38389871]
SW 1116	EC₅₀	28.52 μg/mL Compound: 5-Fluorouracil	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 21889345]
SW 1116	IC₅₀	18.52 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 28363444]
SW 1116	IC₅₀	2.41 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method Antiproliferative activity against human SW1116 cells after 48 hrs by MTT method	[PMID: 23018096]
SW 1116	IC₅₀	37 μM Compound: 5-fluorouracil	Cytotoxicity against SW1116 cells by MTT colometric method Cytotoxicity against SW1116 cells by MTT colometric method	[PMID: 17253861]
SW 1116	IC₅₀	5.26 μM Compound: 5-FU	Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay Cytotoxicity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 24286761]
SW 1116	IC₅₀	76.92 μM Compound: 5-fluorouracil	Cytotoxicity against human SW1116 cells by disk diffusion soft agar colony formation assay Cytotoxicity against human SW1116 cells by disk diffusion soft agar colony formation assay	[PMID: 31117520]
SW 1116	IC₅₀	95.17 μM Compound: 5-FU	Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay Antiproliferative activity against human SW1116 cells after 48 hrs by MTT assay	[PMID: 21962523]
SW-620	CC₅₀	> 2512 μM Compound: 5-Fu	Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
SW-620	EC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 24 hrs by MTT assay Antiproliferative activity against human SW620 cells after 24 hrs by MTT assay	[PMID: 25198997]
SW-620	GI₅₀	0.92 μM Compound: 5-FU	Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SW620 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
SW-620	GI₅₀	0.92 μM Compound: 5-FU	Anticancer activity against human SW-620 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human SW-620 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 27875779]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 28525845]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 29133046]
SW-620	IC₅₀	0.08 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay	[PMID: 31734024]
SW-620	IC₅₀	0.79 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 26617970]
SW-620	IC₅₀	0.79 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay Antiproliferative activity against human SW620 cells incubated for 72 hrs by MTT assay	[PMID: 26291038]
SW-620	IC₅₀	0.92 μM Compound: 5-Fluorouracil	Cytotoxicity against human SW620 cells assessed as cell growth inhibition Cytotoxicity against human SW620 cells assessed as cell growth inhibition	[PMID: 36470105]
SW-620	IC₅₀	10 μM Compound: 5-FU	Cytotoxicity against human SW620 cells after 24 hrs by MTT assay Cytotoxicity against human SW620 cells after 24 hrs by MTT assay	[PMID: 32223193]
SW-620	IC₅₀	102.6 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells assessed as inhibition of cell growth measured after 48 to 72 hrs by XTT assay Antiproliferative activity against human SW620 cells assessed as inhibition of cell growth measured after 48 to 72 hrs by XTT assay	[PMID: 37902628]
SW-620	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human SW620 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay Cytotoxicity against human SW620 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay	[PMID: 37243616]
SW-620	IC₅₀	13.25 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 36269639]
SW-620	IC₅₀	13.84 μM Compound: 5-Fu	Cytotoxicity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SW620 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
SW-620	IC₅₀	14.8 μM Compound: 5-Fu	Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay Cytotoxicity against human SW620 cells after 48 hrs by sulforhodamine B assay	[PMID: 26727215]
SW-620	IC₅₀	15.29 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW-620 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay Antiproliferative activity against human SW-620 cells assessed as inhibition of cell viability measured after 72 hrs by MTT assay	[PMID: 32387836]
SW-620	IC₅₀	17.01 μM Compound: 5-Fu	Antiproliferative activity against human SW-620 cells incubated for 72 hrs by SRB method Antiproliferative activity against human SW-620 cells incubated for 72 hrs by SRB method	[PMID: 39054645]
SW-620	IC₅₀	18.6 μM Compound: 5-Fluorouracil	Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs Cytotoxicity against human SW620 cells assessed as inhibition of tumor growth after 24 hrs	[PMID: 24657568]
SW-620	IC₅₀	18.6 μM Compound: 5-fluorouracil	Cytotoxicity against human SW620 cells Cytotoxicity against human SW620 cells	[PMID: 16996657]
SW-620	IC₅₀	3.38 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 21524829]
SW-620	IC₅₀	32.5 μM Compound: 5-FU	Cytotoxicity against human SW620 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay Cytotoxicity against human SW620 cells assessed inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 37098306]
SW-620	IC₅₀	380 μM Compound: 5-Fluorouracil	Cytotoxicity against human SW620 cells Cytotoxicity against human SW620 cells	[PMID: 22409967]
SW-620	IC₅₀	43 μM Compound: 5-FU	Cytotoxicity against human SW620 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay Cytotoxicity against human SW620 cells assessed as inhibition of cell growth incubated for 24 hrs by MTT assay	[PMID: 38536967]
SW-620	IC₅₀	5.3 μM Compound: 5-FU	Cytotoxicity against human SW620 cells after 72 hrs by MTS assay Cytotoxicity against human SW620 cells after 72 hrs by MTS assay	[PMID: 25066282]
SW-620	IC₅₀	6.68 μM Compound: 5-Fluoruracil	Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells after 72 hrs by MTT assay	[PMID: 22555152]
SW-620	IC₅₀	6.96 μM Compound: 5-FU	Cytotoxicity against human SW-620 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human SW-620 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32203786]
SW-620	IC₅₀	8.7 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells after 3 days by MTT assay Antiproliferative activity against human SW620 cells after 3 days by MTT assay	[PMID: 18424155]
SW-620	IC₅₀	9 μM Compound: 5-FU	Growth inhibition of human SW620 cells after 72 hrs by MTT assay Growth inhibition of human SW620 cells after 72 hrs by MTT assay	[PMID: 18640746]
SW-620	IC₅₀	9 μM Compound: 5-FU	Antitumor activity against human SW620 cells after 24 hrs by MTT assay Antitumor activity against human SW620 cells after 24 hrs by MTT assay	[PMID: 20211564]
SW-620	IC₅₀	9.01 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human SW620 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 38677112]
SW-620	IC₅₀	> 10 μM Compound: 5-FU	Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human SW620 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
SW-620	IC₅₀	> 100 μM Compound: 5-FU	Anticancer activity against human SW620 cells Anticancer activity against human SW620 cells	[PMID: 21449610]
SW13	IC₅₀	> 20 μM Compound: 5-Fu	Cytotoxicity against human SW13 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SW13 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
SW1573	GI₅₀	3.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1573 cells assessed as reduction in cell growth Antiproliferative activity against human SW1573 cells assessed as reduction in cell growth	[PMID: 34847410]
SW1573	GI₅₀	4.1 μM Compound: 5-FU	Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SW1573 cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
SW1573	GI₅₀	4.3 μM Compound: 5-FU	Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay	[PMID: 28728108]
SW1573	GI₅₀	4.3 μM Compound: 5-FU	Antiproliferative activity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
SW1573	GI₅₀	4.3 μM Compound: 5-FU	Growth inhibition of human SW1573 cells measured after 48 hrs by SRB colorimetric assay Growth inhibition of human SW1573 cells measured after 48 hrs by SRB colorimetric assay	[PMID: 37137247]
SW1573	GI₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human SW1573 cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
SW1573	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human SW1573 cells by MTT assay Antiproliferative activity against human SW1573 cells by MTT assay	[PMID: 31546197]
SW1990	IC₅₀	120 μM Compound: Fluorouracil	Cytotoxicity against human SW1990 cells Cytotoxicity against human SW1990 cells	[PMID: 21226488]
SW1990	IC₅₀	121 μM Compound: Fluorouracil	Cytotoxicity against human SW1990 cells Cytotoxicity against human SW1990 cells	[PMID: 21774474]
SW1990	IC₅₀	123 μM Compound: 5-Fu	Cytotoxicity against human SW1990 cells Cytotoxicity against human SW1990 cells	[PMID: 22283451]
SW1990	IC₅₀	126.4 μM Compound: 5-Fu	Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay	[PMID: 26714048]
SW1990	IC₅₀	45 μM Compound: 5-fu	Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay Cytotoxicity against human SW1990 cells after 48 hrs by MTT assay	[PMID: 22304344]
SW48	IC₅₀	4.4 μM Compound: 5-FU	Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay Antiproliferative activity against human SW48 cells after 72 hrs by MTT assay	[PMID: 19743863]
SW48	IC₅₀	5.3 μM Compound: 5-FU	Antiproliferative activity against human SW48 cells after 72 hrs Antiproliferative activity against human SW48 cells after 72 hrs	[PMID: 17548198]
SW48	IC₅₀	5.7 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of SW-48 tumor cell line from colon. Compound was tested for its inhibitory effect on the growth of SW-48 tumor cell line from colon.	10.1016/0960-894X(96)00339-3
SW480	ED₅₀	3.09 μg/mL Compound: 5-fluorouracil	Cytotoxicity against human SW480 cells after 3 days by trypan blue exclusion technique Cytotoxicity against human SW480 cells after 3 days by trypan blue exclusion technique	[PMID: 1800632]
SW480	IC₅₀	12 μM Compound: 5-FU	Cytotoxicity against human SW480 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay Cytotoxicity against human SW480 cells assessed as decrease in cell viability incubated for 48 hrs by SRB assay	[PMID: 37243616]
SW480	IC₅₀	12.4 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 32987314]
SW480	IC₅₀	12.56 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 38634707]
SW480	IC₅₀	13.1 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay	[PMID: 32987314]
SW480	IC₅₀	13.16 μM Compound: 5-FU	Cytotoxicity against human SW480 cells by MTT assay Cytotoxicity against human SW480 cells by MTT assay	[PMID: 18644718]
SW480	IC₅₀	15.3 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay Cytotoxicity against human SW480 cells assessed as reduction in cell viability measured after 24 hrs by MTT assay	[PMID: 32987314]
SW480	IC₅₀	15.71 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 24 hrs by MTT assay Cytotoxicity against human SW480 cells after 24 hrs by MTT assay	[PMID: 22182926]
SW480	IC₅₀	15.71 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay Cytotoxicity against human SW480 cells by after 48 hrs by MTT assay	[PMID: 22579780]
SW480	IC₅₀	15.71 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 23920246]
SW480	IC₅₀	158.2 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 48 hrs by MTT assay Cytotoxicity against human SW480 cells after 48 hrs by MTT assay	[PMID: 23356786]
SW480	IC₅₀	2.1 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay Antiproliferative activity against human SW480 cells after 72 hrs by MTT assay	[PMID: 19743863]
SW480	IC₅₀	21.93 μM Compound: 5-FU	Anticancer activity against human SW480 cells assessed as inhibition of cell proliferation by MTT assay Anticancer activity against human SW480 cells assessed as inhibition of cell proliferation by MTT assay	[PMID: 36439975]
SW480	IC₅₀	217.5 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells assessed as inhibition of cell growth measured after 48 to 72 hrs by XTT assay Antiproliferative activity against human SW480 cells assessed as inhibition of cell growth measured after 48 to 72 hrs by XTT assay	[PMID: 37902628]
SW480	IC₅₀	26.26 μM Compound: 5-FU	Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay Antiproliferative activity against p53 deficient human SW480 cells after 72 hrs by proliferative assay	[PMID: 18469809]
SW480	IC₅₀	3.3 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of human lung squamous cell carcinoma SW 480 solid cell lines. Concentration required for 50% inhibition of human lung squamous cell carcinoma SW 480 solid cell lines.	[PMID: 1992123]
SW480	IC₅₀	3.3 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human colon adenocarcinoma (SW-480) cell line. In vitro inhibitory activity against Human colon adenocarcinoma (SW-480) cell line.	[PMID: 1995905]
SW480	IC₅₀	3.3 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of human colon adenocarcinoma cell lines (SW480). In vitro inhibitory effect on growth of human colon adenocarcinoma cell lines (SW480).	[PMID: 3373480]
SW480	IC₅₀	3.5 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells after 72 hrs Antiproliferative activity against human SW480 cells after 72 hrs	[PMID: 17548198]
SW480	IC₅₀	3.69 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 3 days by SRB assay Cytotoxicity against human SW480 cells after 3 days by SRB assay	[PMID: 24704691]
SW480	IC₅₀	32.72 μM Compound: 5-Fu	Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay	10.1039/C5MD00163C
SW480	IC₅₀	37.5 μM Compound: 1; 5-FU	Growth inhibition of human SW480 cells incubated for 1.5 hrs by MTT assay Growth inhibition of human SW480 cells incubated for 1.5 hrs by MTT assay	[PMID: 38107178]
SW480	IC₅₀	57 μM Compound: 5-FU	Antiproliferative activity against human p53 deficient SW480 cells after 72 hrs by celltiter-glo assay Antiproliferative activity against human p53 deficient SW480 cells after 72 hrs by celltiter-glo assay	[PMID: 20873740]
SW480	IC₅₀	6 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human cancer cell line SW480 after 72 hr of incubation The compound was evaluated for antitumoral activity against human cancer cell line SW480 after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
SW480	IC₅₀	8.1 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells after 72 hrs by MTT method Antiproliferative activity against human SW480 cells after 72 hrs by MTT method	[PMID: 17524655]
SW480	IC₅₀	8.1 μM Compound: 5-Fu	Cytotoxicity against human SW480 cells after 72 hrs by MTT assay Cytotoxicity against human SW480 cells after 72 hrs by MTT assay	[PMID: 23792763]
SW480	IC₅₀	9.7 μM Compound: 5-FU	Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human SW480 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
SW480	IC₅₀	> 30 μM Compound: 5-FU	Antitumor activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay Antitumor activity against human SW480 cells assessed as inhibition of cell proliferation incubated for 72 hrs by MTT assay	[PMID: 35777102]
SW620/5-FU	EC₅₀	> 1000 μM Compound: 5-FU	Reversal of 5-FU resistance against human SW620/5-FU cells assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay Reversal of 5-FU resistance against human SW620/5-FU cells assessed as inhibition of cell proliferation measured after 72 hrs in presence of 5-FU by MTT assay	[PMID: 34411894]
SW620/5-FU	EC₅₀	> 1000 μM Compound: 5-FU	Antiproliferative activity against human SW620/5-FU cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human SW620/5-FU cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 34688013]
SW780	IC₅₀	6.99 μM Compound: 5-FU	Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human SW780 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
SiHa	GI₅₀	6.3 μM Compound: 5FU	Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay Growth inhibition of human SiHa cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
SiHa	IC₅₀	218 μM Compound: 5-Fu	Cytotoxicity against human SiHa cells after 48 hrs by MTT assay Cytotoxicity against human SiHa cells after 48 hrs by MTT assay	[PMID: 22244588]
T-24	IC₅₀	0.5 μg/mL Compound: 5-FU	Tested for cytotoxicity against antigen negative T-24 bladder carcinoma cells having only 3-5% antigen expression Tested for cytotoxicity against antigen negative T-24 bladder carcinoma cells having only 3-5% antigen expression	[PMID: 8496926]
T-24	IC₅₀	12.89 μM Compound: 5-FU	Cytotoxicity against human T24 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay Cytotoxicity against human T24 cells assessed as inhibition of cell growth incubated for 48 hrs by CCK-8 assay	[PMID: 33740546]
T-24	IC₅₀	22 μM Compound: 5-FU (5-fluorouracil)	Compound was tested for its inhibitory effect on the growth of T24 tumor cell line from bladder. Compound was tested for its inhibitory effect on the growth of T24 tumor cell line from bladder.	10.1016/0960-894X(96)00339-3
T-24	IC₅₀	25.23 μM Compound: 5-FU	Antiproliferative activity against human T24 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay Antiproliferative activity against human T24 cells assessed as reduction in cell viability measured for 24 hrs by MTT assay	[PMID: 37122546]
T-24	IC₅₀	37.56 μM Compound: 5-FU	Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay Cytotoxicity against human T24 cells assessed as cell viability after 48 hrs by MTT assay	[PMID: 25841199]
T-24	IC₅₀	39.4 μM Compound: 5-Fu	Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human T24 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
T-24	IC₅₀	4.1 μM Compound: 5-FU	Tested for cytotoxicity against antigen negative T-24 bladder carcinoma cells having only 3-5% antigen expression Tested for cytotoxicity against antigen negative T-24 bladder carcinoma cells having only 3-5% antigen expression	[PMID: 8496926]
T-24	IC₅₀	40.14 μM Compound: 5-FU	Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human T24 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 28754470]
T-24	IC₅₀	40.14 μM Compound: 5-FU	Antiproliferative activity against human T-24 cells by MTT assay Antiproliferative activity against human T-24 cells by MTT assay	[PMID: 33109400]
T-24	IC₅₀	40.14 μM Compound: 5-FU	Antiproliferative activity against human T24 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human T24 cells incubated for 48 hrs by MTT assay	[PMID: 37972528]
T-24	IC₅₀	40.57 μM Compound: 5-Fu	Cytotoxicity against human T24 cells after 2 days by MTT assay Cytotoxicity against human T24 cells after 2 days by MTT assay	[PMID: 25841196]
T-24	IC₅₀	6.1 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of human lung squamous cell carcinoma T24 solid cell lines. Concentration required for 50% inhibition of human lung squamous cell carcinoma T24 solid cell lines.	[PMID: 1992123]
T-24	IC₅₀	6.1 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human bladder transitional-cell carcinoma (T-24) cell line. In vitro inhibitory activity against Human bladder transitional-cell carcinoma (T-24) cell line.	[PMID: 1995905]
T-24	IC₅₀	6.1 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of human bladder transitional-carcinoma cell lines (T24). In vitro inhibitory effect on growth of human bladder transitional-carcinoma cell lines (T24).	[PMID: 3373480]
T-24	IC₅₀	6 μg/mL Compound: 5-FU	The compound was evaluated for antitumoral activity against human cancer cell line T24 after 72 hr of incubation The compound was evaluated for antitumoral activity against human cancer cell line T24 after 72 hr of incubation	10.1016/S0960-894X(01)80742-3
T47D	ED₅₀	50.2 μM Compound: 5-Fluorouracil	Cytotoxicity against human T47D cells after 3 hrs by Alamar Blue assay Cytotoxicity against human T47D cells after 3 hrs by Alamar Blue assay	[PMID: 24020806]
T47D	GI₅₀	29 μM Compound: 5-FU	Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
T47D	GI₅₀	43 μM Compound: 5-Fluorouracil	Antiproliferative activity against human T47D cells assessed as reduction in cell growth Antiproliferative activity against human T47D cells assessed as reduction in cell growth	[PMID: 34847410]
T47D	GI₅₀	47 μM Compound: 5-FU	Antiproliferative activity against human T47D cells after 48 hrs by SRB assay Antiproliferative activity against human T47D cells after 48 hrs by SRB assay	[PMID: 28728108]
T47D	GI₅₀	47 μM Compound: 5-FU	Antiproliferative activity against human T47D cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human T47D cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
T47D	GI₅₀	47 μM Compound: 5-FU	Growth inhibition of human T47D cells measured after 48 hrs by SRB colorimetric assay Growth inhibition of human T47D cells measured after 48 hrs by SRB colorimetric assay	[PMID: 37137247]
T47D	GI₅₀	47 μM Compound: 5-Fluorouracil	Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
T47D	GI₅₀	47 μM Compound: 5-fluorouracil	Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay Antiproliferative activity against human T47D cells expressing estrogen receptor after 48 hrs by SRB assay	[PMID: 20438092]
T47D	GI₅₀	8.12 μM Compound: 5-FU	Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay Growth inhibition of human T47D cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
T47D	GI₅₀	8.12 μM Compound: 5-FU	Anticancer activity against human T47D cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human T47D cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
T47D	IC₅₀	0.6 μM Compound: 5-FU	Antiproliferative activity against human T47D cells after 72 hrs by MTT assay Antiproliferative activity against human T47D cells after 72 hrs by MTT assay	[PMID: 19743863]
T47D	IC₅₀	10.56 μM Compound: 5-Fu	Cytotoxicity against human T47D cells after 3 days by SRB assay Cytotoxicity against human T47D cells after 3 days by SRB assay	[PMID: 24704691]
T47D	IC₅₀	12.1 μM Compound: 5-FU	Antiproliferative activity against human T47D cells after 48 hrs by MTT assay Antiproliferative activity against human T47D cells after 48 hrs by MTT assay	[PMID: 28400238]
T47D	IC₅₀	171.06 μM Compound: Fluorouracil	Cytotoxicity against human T47D cells after 48 hrs by MTT assay Cytotoxicity against human T47D cells after 48 hrs by MTT assay	[PMID: 28789892]
T47D	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human T47D cells by MTT assay Antiproliferative activity against human T47D cells by MTT assay	[PMID: 31546197]
T47D	IC₅₀	51.7 μM Compound: 5-FU	Growth inhibition of human T47D cells after 24 hrs by MTT assay Growth inhibition of human T47D cells after 24 hrs by MTT assay	[PMID: 28011220]
T47D	IC₅₀	51.8 μM Compound: 5-FU	Cytotoxicity against human T47D cells after 24 hrs by MTT assay Cytotoxicity against human T47D cells after 24 hrs by MTT assay	[PMID: 23202484]
T47D	IC₅₀	6.7 μM Compound: 5-FU	Antiproliferative activity against human T47D cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay Antiproliferative activity against human T47D cells assessed as reduction in cell viability incubated for 24 hrs by sulforhodamine B assay	[PMID: 34847409]
T47D	IC₅₀	7.9 μM Compound: 5-FU	Cytotoxicity against human T47D cells after 72 hrs by SRB assay Cytotoxicity against human T47D cells after 72 hrs by SRB assay	[PMID: 25462277]
T47D	IC₅₀	8.12 μM Compound: 5-Fluorouracil	Cytotoxicity against human T47D cells assessed as cell growth inhibition Cytotoxicity against human T47D cells assessed as cell growth inhibition	[PMID: 36470105]
T47D	IC₅₀	8.91 μM Compound: 5FU	Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay Cytotoxicity against human T47D cells incubated for 72 hrs by SRB assay	[PMID: 22867707]
T84	IC₅₀	3.4 μM Compound: 5-Fu	Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay Antiproliferative activity against human T84 cells after 3 days by sulforhodamine B assay	[PMID: 30248657]
T84	IC₅₀	6.2 μM Compound: 5-FU	Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay Antiproliferative activity against human T84 cells assessed as cellular DNA content after 96 hrs by CyQUANT NF fluorescence assay	[PMID: 26731300]
T84	IC₅₀	> 10 μM Compound: 5-FU	Antiproliferative activity against human T84 cells assessed as reduction in cell viability after 72 hrs by MTT assay Antiproliferative activity against human T84 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 32127259]
T98G	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human T98G cells assessed as inhibition of cell growth Antiproliferative activity against human T98G cells assessed as inhibition of cell growth	[PMID: 36089111]
TE-1	IC₅₀	16.53 μM Compound: 5-Fu	Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay Antiproliferative activity against human TE1 cells after 72 hrs by MTT assay	[PMID: 29635165]
TE-1	IC₅₀	16.53 μM Compound: 5-Fu	Cytotoxicity against human TE1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay Cytotoxicity against human TE1 cells assessed as inhibition of cell proliferation after 72 hrs by MTT assay	[PMID: 30388465]
TE-1	IC₅₀	17.32 μM Compound: 5-FU	Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay Cytotoxicity against human TE1 cells assessed as growth inhibition after 72 hrs by CCK8 assay	[PMID: 27597411]
TE-1	IC₅₀	7.73 μM Compound: 5-fluorouracil	Antiproliferative activity against human TE-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human TE-1 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 36893627]
TE-2	IC₅₀	3.9 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of human lung squamous cell carcinoma TE2 solid cell lines. Concentration required for 50% inhibition of human lung squamous cell carcinoma TE2 solid cell lines.	[PMID: 1992123]
TE-2	IC₅₀	3.9 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human esophagus adenocarcinoma (TE-2) cell line. In vitro inhibitory activity against Human esophagus adenocarcinoma (TE-2) cell line.	[PMID: 1995905]
TE-2	IC₅₀	3.9 μg/mL Compound: 5-FU	In vitro inhibitory effect on growth of human esophagus adenocarcinoma cell lines (TE2). In vitro inhibitory effect on growth of human esophagus adenocarcinoma cell lines (TE2).	[PMID: 3373480]
THP-1	IC₅₀	0.01 μM Compound: 5-Fluorouracil	Cytotoxicity against human THP1 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay Cytotoxicity against human THP1 cells assessed as inhibition of cell growth after 48 hrs by sulforhodamine B assay	10.1039/C5MD00289C
THP-1	IC₅₀	0.04 μM Compound: 5-Fluorouracil	Cytotoxicity against human THP1 cells after 48 hrs by SRB assay Cytotoxicity against human THP1 cells after 48 hrs by SRB assay	[PMID: 25259515]
THP-1	IC₅₀	0.54 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human THP1 cells after 24 hrs by MTT assay Cytotoxicity against human THP1 cells after 24 hrs by MTT assay	[PMID: 23352638]
THP-1	IC₅₀	1 μM Compound: 5-FU	Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human THP1 cells after 48 hrs by sulforhodamine B assay	[PMID: 23501113]
THP-1	IC₅₀	1.7 μM Compound: 5-FU	Cytotoxicity against human THP1 cells after 48 hrs by MTT assay Cytotoxicity against human THP1 cells after 48 hrs by MTT assay	[PMID: 26854375]
THP-1	IC₅₀	4.87 μM Compound: 5-FU	Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay Antiproliferative activity against human THP1 cells treated for 24 hrs measured after 72 hrs by MTT assay	[PMID: 29037951]
TIG-3	IC₅₀	8.4 μM Compound: 5-fluorouracil	Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay Antiproliferative activity against human TIG3 cells after 72 hrs by WST8 assay	[PMID: 25919052]
TK-10	GI₅₀	1.12 μM Compound: 5-FU	Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human TK10 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
TK-10	GI₅₀	1.12 μM Compound: 5-FU	Anticancer activity against human TK-10 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human TK-10 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
TK-10	IC₅₀	1.12 μM Compound: 5-Fluorouracil	Cytotoxicity against human TK-10 cells assessed as cell growth inhibition Cytotoxicity against human TK-10 cells assessed as cell growth inhibition	[PMID: 36470105]
TSU	IC₅₀	3.6 μM Compound: 5-FU	Concentration required to inhibit proliferation of TSU prostate cancer cell lines Concentration required to inhibit proliferation of TSU prostate cancer cell lines	[PMID: 15341952]
U-251	GI₅₀	0.9 μM Compound: 5-FU	Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human U251 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
U-251	GI₅₀	0.92 μM Compound: 5-FU	Anticancer activity against human U-251 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human U-251 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
U-251	GI₅₀	30.1 μM Compound: 5-Fu	Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay Antiproliferative activity against human U251 cells incubated for 48 hrs by MTT assay	[PMID: 32832031]
U-251	GI₅₀	69.6 nM Compound: 5FU	Growth inhibition of human U251 cells after 48 hrs by SRB assay Growth inhibition of human U251 cells after 48 hrs by SRB assay	[PMID: 23094992]
U-251	GI₅₀	82 μM Compound: 5-Fu	Growth inhibition of human U251 cells after 48 hrs by SRB assay Growth inhibition of human U251 cells after 48 hrs by SRB assay	[PMID: 22512908]
U-251	IC₅₀	0.54 μM Compound: 5-fluorouracil	Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay Cytotoxicity against human U251 cells assessed as reduction in cell viability by SRB assay	[PMID: 30660827]
U-251	IC₅₀	0.92 μM Compound: 5-Fluorouracil	Cytotoxicity against human U-251 cells assessed as cell growth inhibition Cytotoxicity against human U-251 cells assessed as cell growth inhibition	[PMID: 36470105]
U-251	IC₅₀	24.69 μM Compound: 5-Fu	Cytotoxicity against human U251 cells after 48 hrs by MTT assay Cytotoxicity against human U251 cells after 48 hrs by MTT assay	[PMID: 27133593]
U-251	IC₅₀	29.49 μM Compound: 5-Fu	Antiproliferative activity against human U-251 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay Antiproliferative activity against human U-251 cells assessed as inhibition of cell growth incubated for 72 hrs by MTT assay	[PMID: 39163776]
U-251	IC₅₀	38.68 μM Compound: 5-Fu	Cytotoxicity against human U251 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay Cytotoxicity against human U251 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay	[PMID: 27400887]
U-251	IC₅₀	48.68 μM Compound: 5FU	Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay Cytotoxicity against human U251 cells assessed as decrease in cell proliferation after 48 hrs by MTT colorimetric assay	[PMID: 28038327]
U-266	IC₅₀	43.48 μM Compound: 2; 5-FU	Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human U266 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
U-266	IC₅₀	66.22 μM Compound: 2; 5-FU	Antiproliferative activity against human U266 cells after 48 hrs by MTT assay Antiproliferative activity against human U266 cells after 48 hrs by MTT assay	[PMID: 29202398]
U-87MG ATCC	GI₅₀	13 μM Compound: 5-FU	Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay Neurotoxicity against human U87 cells assessed as growth inhibition measured after 48 hrs by MTT assay	[PMID: 27688184]
U-87MG ATCC	IC₅₀	15.48 μM Compound: F	Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human U87MG cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 27210438]
U-87MG ATCC	IC₅₀	18.25 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 72 hrs by Z2 coulter counter method	[PMID: 27081742]
U-87MG ATCC	IC₅₀	2.42 μM Compound: 5-Fluorouracil	Antiproliferative activity against human U87MG cells assessed as reduction in cell viability after 48 hrs by MTT assay Antiproliferative activity against human U87MG cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 31546197]
U-87MG ATCC	IC₅₀	219.6 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 48 hrs by Z2 coulter counter method Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 48 hrs by Z2 coulter counter method	[PMID: 27081742]
U-87MG ATCC	IC₅₀	22 μM Compound: 5-Fu	Cytotoxicity against human U87 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay Cytotoxicity against human U87 cells assessed as inhibition of cell proliferation after 48 hrs by MTT assay	[PMID: 30568759]
U-87MG ATCC	IC₅₀	3.61 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay Cytotoxicity against human U87MG cells assessed as growth inhibition after 72 hrs by MTT assay	[PMID: 26735909]
U-87MG ATCC	IC₅₀	3.65 μM Compound: 5-Fluorouracil	Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay Antiproliferative activity against human U87MG cells after 48 hrs by MTT assay	[PMID: 27092413]
U-87MG ATCC	IC₅₀	38.2 μM Compound: 5-Fu	Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay Antiproliferative activity against human U87 cells assessed as cell-growth inhibition after 48 hrs by MTT assay	[PMID: 25453794]
U-87MG ATCC	IC₅₀	4.94 μM Compound: 5-Fu	Antiproliferative activity against human U-87 MG cells incubated for 72 hrs by SRB assay Antiproliferative activity against human U-87 MG cells incubated for 72 hrs by SRB assay	[PMID: 39054645]
U-87MG ATCC	IC₅₀	45.3 μM Compound: 5-FU	Antiproliferative activity against human U87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Antiproliferative activity against human U87 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 30739827]
U-87MG ATCC	IC₅₀	49298 μM Compound: 5-FU	Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 24 hrs by Z2 coulter counter method Cytotoxicity against human U87MG cells assessed as reduction in cell viability after 24 hrs by Z2 coulter counter method	[PMID: 27081742]
U-87MG ATCC	IC₅₀	5.61 μM Compound: 5-Fu	Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay Antiproliferative activity against human U87 cells assessed as cell growth inhibition after 72 hrs by MTT assay	[PMID: 27105028]
U-87MG ATCC	IC₅₀	> 50 μM Compound: 5-FU	Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Antiproliferative activity against human U-87 MG cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 33538581]
U-937	IC₅₀	0.11 μg/mL Compound: 5-FU	In vitro inhibitory activity against growth of Human histocytic lymphoma (U937) cells In vitro inhibitory activity against growth of Human histocytic lymphoma (U937) cells	[PMID: 1995901]
U-937	IC₅₀	0.5 μg/mL Compound: 5-F-Ura	In vitro antitumor activity in U-937 cell lines In vitro antitumor activity in U-937 cell lines	[PMID: 8648611]
U-937	IC₅₀	0.87 μg/mL Compound: 5-Fluorouracil	Cytotoxicity against human U937 cells after 24 hrs by MTT assay Cytotoxicity against human U937 cells after 24 hrs by MTT assay	[PMID: 23352638]
U-937	IC₅₀	1.07 μM Compound: 5-FU	Cytotoxicity against human U937 cells after 72 hrs by MTT assay Cytotoxicity against human U937 cells after 72 hrs by MTT assay	[PMID: 22959518]
U-937	IC₅₀	23.93 μM Compound: 5-Fu	Cytotoxicity against human U937 cells after 48 hrs by MTT assay Cytotoxicity against human U937 cells after 48 hrs by MTT assay	[PMID: 23558238]
U-937	IC₅₀	23.93 μM Compound: 5-Fu	Growth inhibition against human U937 cells after 48 hrs by MTT assay Growth inhibition against human U937 cells after 48 hrs by MTT assay	[PMID: 23999046]
U-937	IC₅₀	28.76 μM Compound: 2; 5-FU	Antiproliferative activity against human U937 cells after 48 hrs by MTT assay Antiproliferative activity against human U937 cells after 48 hrs by MTT assay	[PMID: 29202398]
U-937	IC₅₀	3.5 μg/mL Compound: 5-FU	Concentration required for 50% inhibition of cell growth of U937 leukemic cell lines in human. Concentration required for 50% inhibition of cell growth of U937 leukemic cell lines in human.	[PMID: 1992123]
U-937	IC₅₀	3.5 μg/mL Compound: 5-FU	In vitro inhibitory activity against Human histiocytic lymphoma (U-937) cell line. In vitro inhibitory activity against Human histiocytic lymphoma (U-937) cell line.	[PMID: 1995905]
U-937	IC₅₀	4.7 μM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) U937 cells after 96 hr by MTT assay Cytotoxicity against Homo sapiens (human) U937 cells after 96 hr by MTT assay	10.1007/s00044-011-9778-y
U-937	IC₅₀	56.28 μM Compound: 5-Fu	Antiproliferative activity against human U937 cells after 48 hrs by MTT assay Antiproliferative activity against human U937 cells after 48 hrs by MTT assay	[PMID: 29958763]
U-937	IC₅₀	9.56 μM Compound: 2; 5-FU	Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay Antiproliferative activity against human U937 cells in presence of ubenimex after 48 hrs by MTT assay	[PMID: 29202398]
U2OS	IC₅₀	13.02 μM Compound: 5-Fu	Antiproliferative activity against human U2OS cells after 72 hrs by MTT assay Antiproliferative activity against human U2OS cells after 72 hrs by MTT assay	[PMID: 35609396]
U2OS	IC₅₀	13.18 μM Compound: 5-FU	Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay Antiproliferative activity against human U2OS cells expressing p53 gene after 72 hrs by proliferative assay	[PMID: 18469809]
U2OS	IC₅₀	16 μM Compound: 5-FU	Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay Antiproliferative activity against human U2OS cells expressing p53 after 72 hrs by celltiter-glo assay	[PMID: 20873740]
U2OS	IC₅₀	7.2 μg/mL Compound: 5-FU	Cytotoxicity against human U2OS cells after 36 hrs by MTT assay Cytotoxicity against human U2OS cells after 36 hrs by MTT assay	[PMID: 20961091]
U2OS	IC₅₀	> 20 μM Compound: 5-FU	Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay Cytotoxicity against human U2OS cells assessed as reduction in cell viability incubated for 72 hrs by MTS assay	[PMID: 36331508]
UACC-257	GI₅₀	3.55 μM Compound: 5-FU	Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UACC257 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
UACC-257	GI₅₀	3.55 μM Compound: 5-FU	Anticancer activity against human UACC-257 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human UACC-257 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
UACC-257	IC₅₀	3.55 μM Compound: 5-Fluorouracil	Cytotoxicity against human UACC-257 cells assessed as cell growth inhibition Cytotoxicity against human UACC-257 cells assessed as cell growth inhibition	[PMID: 36470105]
UACC-62	GI₅₀	0.52 μM Compound: 5-FU	Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UACC62 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
UACC-62	GI₅₀	0.52 μM Compound: 5-FU	Anticancer activity against human UACC-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human UACC-62 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
UACC-62	IC₅₀	0.52 μM Compound: 5-Fluorouracil	Cytotoxicity against human UACC-62 cells assessed as cell growth inhibition Cytotoxicity against human UACC-62 cells assessed as cell growth inhibition	[PMID: 36470105]
UACC-62	IC₅₀	264 μM Compound: 5-Fluorouracil	Cytotoxicity against human UACC62 cells after 48 hrs by MTT assay Cytotoxicity against human UACC62 cells after 48 hrs by MTT assay	[PMID: 24177365]
UACC-812	IC₅₀	3.1 μM Compound: 5-FU	Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay Antiproliferative activity against human UACC-812 cells after 72 hrs by MTT assay	[PMID: 19743863]
UO-31	GI₅₀	1.42 μM Compound: 5-FU	Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human UO31 cells after 48 hrs by sulforhodamine B assay	[PMID: 23887055]
UO-31	GI₅₀	1.42 μM Compound: 5-FU	Anticancer activity against human UO-31 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay Anticancer activity against human UO-31 cells assessed as cell growth inhibition incubated for 48 hrs by SRB assay	[PMID: 35182815]
UO-31	IC₅₀	1.42 μM Compound: 5-Fluorouracil	Cytotoxicity against human UO-31 cells assessed as cell growth inhibition Cytotoxicity against human UO-31 cells assessed as cell growth inhibition	[PMID: 36470105]
Vero	IC₅₀	0.05 mM Compound: 5-FU	Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Chlorocebus aethiops (African green monkey) Vero cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
Vero	IC₅₀	0.2 μM Compound: 5-fluorouracil	Cytotoxicity against Vero cells Cytotoxicity against Vero cells	[PMID: 17234303]
Vero	IC₅₀	4.5 μM Compound: 1, 5-FU	Growth inhibition of african green monkey Vero cells by crystal violet assay Growth inhibition of african green monkey Vero cells by crystal violet assay	[PMID: 23075414]
Vero	IC₅₀	6.4 μg/mL Compound: 5-FU	Cytotoxicity against African green monkey Vero cells after 96 hrs by MTT assay Cytotoxicity against African green monkey Vero cells after 96 hrs by MTT assay	[PMID: 23022735]
Vero	IC₅₀	6.5 μg/mL Compound: 5-Fu	Cytotoxicity against african green monkey Vero cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against african green monkey Vero cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
Vero	IC₅₀	6.5 μg/mL Compound: 5-Fu	Cytotoxicity against african green monkey Vero cells after 96 hrs by MTT assay Cytotoxicity against african green monkey Vero cells after 96 hrs by MTT assay	[PMID: 22204901]
Vero	IC₅₀	6.81 μM Compound: 5-fluorouracil	Tested in vitro for cytotoxicity against Vero cells Tested in vitro for cytotoxicity against Vero cells	[PMID: 10072683]
Vero	IC₅₀	8 μM Compound: 5-FU	Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay	[PMID: 23800391]
Vero	IC₅₀	9.71 μM Compound: 5-Fu	Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay Cytotoxicity against African green monkey Vero cells after 72 hrs by MTT assay	[PMID: 23685571]
Vero	IC₅₀	> 100 μM Compound: 5-Fu	Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay Cytotoxicity against african green monkey Vero cells after 72 hrs by MTT assay	[PMID: 22687745]
WI-38	IC₅₀	0.02 mM Compound: 5-FU	Cytotoxicity against Homo sapiens (human) WI38 cells assessed as inhibition of cell survival after 96 hr Cytotoxicity against Homo sapiens (human) WI38 cells assessed as inhibition of cell survival after 96 hr	10.1007/s00044-012-0201-0
WI-38	IC₅₀	0.051 mM Compound: 5-Fluorouracil	Cytotoxicity in human WI38 cells assessed as reduction in cell viability by MTT assay Cytotoxicity in human WI38 cells assessed as reduction in cell viability by MTT assay	[PMID: 28334654]
WI-38	IC₅₀	0.192 μM Compound: 5-FU	Cytotoxicity in human WI-38 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay Cytotoxicity in human WI-38 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay	[PMID: 36921275]
WI-38	IC₅₀	0.94 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 27875779]
WI-38	IC₅₀	0.94 μM Compound: 5-FU	Cytotoxicity against human WI38 cells after 72 hrs by MTT assay Cytotoxicity against human WI38 cells after 72 hrs by MTT assay	[PMID: 28525845]
WI-38	IC₅₀	0.94 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 29133046]
WI-38	IC₅₀	10 μM Compound: 5-FU	Cytotoxicity against human WI38 cells after 3 days by MTT assay Cytotoxicity against human WI38 cells after 3 days by MTT assay	[PMID: 18424155]
WI-38	IC₅₀	10 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay	[PMID: 23800391]
WI-38	IC₅₀	18.5 μM Compound: 5-FU	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 21524829]
WI-38	IC₅₀	201.9 μM Compound: 5-FU	Cytotoxicity in human W138 cells assessed as growth inhibition incubated for 24 hrs by MTT assay Cytotoxicity in human W138 cells assessed as growth inhibition incubated for 24 hrs by MTT assay	[PMID: 31128448]
WI-38	IC₅₀	24.66 μM Compound: 5-Fluoruracil	Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay Antiproliferative activity against human WI38 cells after 72 hrs by MTT assay	[PMID: 22555152]
WI-38	IC₅₀	3.2 μg/mL Compound: 5-Fu	Cytotoxicity against human WI38 cells assessed as loss of cell monolayers after 96 hrs Cytotoxicity against human WI38 cells assessed as loss of cell monolayers after 96 hrs	[PMID: 21130542]
WI-38	IC₅₀	3.2 μg/mL Compound: 5-Fu	Cytotoxicity against human WI38 cells after 96 hrs by MTT assay Cytotoxicity against human WI38 cells after 96 hrs by MTT assay	[PMID: 22204901]
WI-38	IC₅₀	3.325 μM Compound: 5-FU	Cytotoxicity against human WI-38 cells incubated for 72 hrs by MTT assay Cytotoxicity against human WI-38 cells incubated for 72 hrs by MTT assay	[PMID: 36335743]
WI-38	IC₅₀	38.91 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as growth inhibition after 48 hrs by MTT assay	[PMID: 26873416]
WI-38	IC₅₀	4 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 48 hrs by MTT assay	[PMID: 27343853]
WI-38	IC₅₀	4.1 μM Compound: 5-Fu	Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay	[PMID: 31276896]
WI-38	IC₅₀	4 μg/mL Compound: 5-FU	Cytotoxicity against human WI38 cells after 96 hrs by MTT assay Cytotoxicity against human WI38 cells after 96 hrs by MTT assay	[PMID: 23022735]
WI-38	IC₅₀	5.7 μM Compound: 5-Fluorouracil	Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay Cytotoxicity in human WI38 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay	[PMID: 28926764]
WI-38	IC₅₀	5.73 μM Compound: 5-Fluorouracil	Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay Cytotoxicity against human W138 cells assessed as decrease in cell viability after 48 hrs by MTT assay	[PMID: 28623814]
WI-38	IC₅₀	6.8 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay Cytotoxicity against human WI38 cells assessed as decrease in cell viability after 72 hrs by WST8 assay	[PMID: 28558970]
WI-38	IC₅₀	62 μM Compound: 5-Fluorouracil	Cytotoxicity against human WI-38 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay Cytotoxicity against human WI-38 cells assessed as number of viable cells measured after 48 hrs by MTT based colorimetric assay	[PMID: 36970146]
WI-38	IC₅₀	78.5 μM Compound: 5-FU	Cytotoxicity against human WI-38 cells assessed as reduction in cell viability after 72 hrs by SRB assay Cytotoxicity against human WI-38 cells assessed as reduction in cell viability after 72 hrs by SRB assay	[PMID: 32485532]
WI-38	IC₅₀	8.4 μM Compound: 5-FU	Cytotoxicity activity against human WI38 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay Cytotoxicity activity against human WI38 cells assessed as reduction in cell viability measured after 48 hrs by MTT assay	[PMID: 30856408]
WI-38	IC₅₀	9.3 μM Compound: 5-FU	Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human WI38 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 27951487]
WI-38	IC₅₀	> 40 μM Compound: 5-Fu	Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay Antiproliferative activity against human WI-38 cells assessed as cell growth inhibition measured after 48 hrs by MTT assay	[PMID: 35092899]
WISH	IC₅₀	7.1 μM Compound: 5-FU	Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human WISH cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 27951487]
WM 266-4	GI₅₀	28.76 μM Compound: 5-Fu	Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay Antiproliferative activity against human WM266.4 cells after 24 hrs by MTT assay	[PMID: 24934992]
WiDr	GI₅₀	49 μM Compound: 5-FU	Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay	[PMID: 28728108]
WiDr	GI₅₀	49 μM Compound: 5-FU	Antiproliferative activity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay Antiproliferative activity against human WiDr cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
WiDr	GI₅₀	49 μM Compound: 5-FU	Growth inhibition of human WiDr cells measured after 48 hrs by SRB colorimetric assay Growth inhibition of human WiDr cells measured after 48 hrs by SRB colorimetric assay	[PMID: 37137247]
WiDr	GI₅₀	49 μM Compound: 5-Fluorouracil	Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay Antiproliferative activity against human WiDr cells after 48 hrs by sulforhodamine B assay	[PMID: 25752525]
WiDr	GI₅₀	49 μM Compound: 5-Fluorouracil	Antiproliferative activity against human WiDr cells assessed as reduction in cell growth Antiproliferative activity against human WiDr cells assessed as reduction in cell growth	[PMID: 34847410]
WiDr	GI₅₀	50 μM Compound: 5-FU	Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay Growth inhibition of human WiDr cells after 48 hrs by sulforhodamine B assay	[PMID: 19664930]
WiDr	IC₅₀	10.5 μM Compound: 5-FU	Anticancer activity against human WiDr cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay Anticancer activity against human WiDr cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay	[PMID: 34425478]
WiDr	IC₅₀	4.3 μM Compound: 5-Fluorouracil	Antiproliferative activity against human WiDr cells by MTT assay Antiproliferative activity against human WiDr cells by MTT assay	[PMID: 31546197]
ZR-75-1	GI₅₀	2.3 μM Compound: 5FU	Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay Growth inhibition of human ZR-75-1 cells after 48 hrs by sulforhodamine B assay	[PMID: 21489802]
hTERT-BJ	GI₅₀	5.5 μM Compound: 5-FU	Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay Antiproliferative activity against human hTERT-BJ cells after 48 hrs by SRB assay	[PMID: 28728108]
hTERT-BJ	GI₅₀	5.5 μM Compound: 5-FU	Cytotoxicity against human hTERT-BJ cells assessed as growth inhibition after 48 hrs by SRB assay Cytotoxicity against human hTERT-BJ cells assessed as growth inhibition after 48 hrs by SRB assay	[PMID: 31376562]
hTERT-BJ	GI₅₀	5.5 μM Compound: 5-Fluorouracil	Antiproliferative activity against human hTERT-BJ cells assessed as reduction in cell growth Antiproliferative activity against human hTERT-BJ cells assessed as reduction in cell growth	[PMID: 34847410]
hTERT-BJ	IC₅₀	5.5 μM Compound: 5-Fluorouracil	Cytotoxicity activity against human hTERT-BJ cells by MTT assay Cytotoxicity activity against human hTERT-BJ cells by MTT assay	[PMID: 31546197]

In Vitro

5-Fluorouracil (5-Fu) and NSC 123127 (Dox) show synergistic anticancer efficacy. The IC₅₀ value of 5-Fu/Dox-DNM toward human breast cancer (MDA-MB-231) cells is 0.25 μg/mL, presenting an 11.2-fold and 6.1-fold increase in cytotoxicity compared to Dox-DNM and 5-Fu-DNM, respectively^[1]. In 5-fluorouracil (5-FU) and CDDP treated NFBD1-inhibited NPC cells, the NFBD1 expression in NPC CNE1 cell lines is depleted using lentivirus-mediated short hairpin RNA, and the sensitivity of these cells is elevated. NFBD1 knockdown leads to an obvious induction of apoptosis in CDDP- or 5-FU-treated CNE1 cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

5-Fluorouracil (23 mg/kg, 3 times/week) for 14 days, induces accelerated gastrointestinal transit associated with acute intestinal inflammation at day 3 after the start of treatment, which may have led to persistent changes in the ENS observed after days 7 and 14 of treatment contributing to delayed gastrointestinal transit and colonic dysmotility^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

Molecular Weight

130.08

Formula

C₄H₃FN₂O₂

CAS No.

51-21-8

Appearance

Solid

Color

White to off-white

SMILES

O=C(N1)NC=C(F)C1=O

Structure Classification

Others

Initial Source

Endogenous metabolite

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (384.38 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

1 M Ammonium hydroxide : 50 mg/mL (384.38 mM; Need ultrasonic)

H₂O : 10 mg/mL (76.88 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	7.6876 mL	38.4379 mL	76.8758 mL
5 mM	1.5375 mL	7.6876 mL	15.3752 mL
10 mM	0.7688 mL	3.8438 mL	7.6876 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (19.22 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (19.22 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (19.22 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.
Protocol 4

Add each solvent one by one: 5% DMSO 40% PEG300 5% Tween-80 50% Saline
Solubility: ≥ 2.5 mg/mL (19.22 mM); Clear solution
Protocol 5

Add each solvent one by one: 5% DMSO 95% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (19.22 mM); Clear solution
Protocol 6

Add each solvent one by one: 5% DMSO 95% Saline
Solubility: 2.5 mg/mL (19.22 mM); Clear solution; Need ultrasonic

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 25 mg/mL (192.19 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 99.99%

Select Batch:

Data Sheet (285 KB) SDS (644 KB)

COA (254 KB) HNMR (233 KB) RP-HPLC (205 KB) MS (68 KB) Elemental Analysis Report (113 KB)

Handling Instructions (2659 KB)

References

[1]. Han R, et al. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and NSC 123127 for enhanced therapeutic efficacy. J Drug Target. 2016 Jun 29:1-28. [Epub ahead of print] [Content Brief]

[2]. Zeng Q, et al. Knockdown of NFBD1/MDC1 enhances chemosensitivity to NSC 119875 or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells. Mol Cell Biochem. 2016 Jul;418(1-2):137-46. [Content Brief]

[3]. Jones DH, et al. Ten-Year and Beyond Follow-up After Treatment With Highly Purified Liquid-Injectable Silicone for HIV-Associated Facial Lipoatrophy: A Report of 164 Patients. Dermatol Surg. 2019 Jul;45(7):941-948. [Content Brief]

[4]. McQuade RM, et al. Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anticancer chemotherapeutic agent 5-fluorouracil. Neurogastroenterol Motil. 2016 Jun 28. [Content Brief]

[5]. Yin L, et al. Antitumor effects of oncolytic herpes simplex virus type 2 against colorectal cancer in vitro and in vivo. Ther Clin Risk Manag. 2017 Feb 7;13:117-130. [Content Brief]

[6]. Snyder SM, et al. Initial Experience with Topical Fluorouracil for Treatment of HIV-Associated Anal Intraepithelial Neoplasia. J Int Assoc Physicians AIDS Care (Chic). 2011;10(2):83-88. [Content Brief]

[7]. Pek Yee Lum, et al. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell. 2004 Jan 9;116(1):121-37. [Content Brief]

Animal Administration
^[2]

Mice receive intraperitoneal injections of 5-FU (23 mg/kg), 3 times a week via a 26 gauge needle. 5-FU is dissolved in 100% dimethyl sulfoxide (DMSO) to make 1 M/L stock solution refrigerated at −20°C. The stock is then defrosted and diluted with sterile water to make 0.1 M/L (10% DMSO) solutions for intraperitoneal injections. The dose of 5-FU is calculated to be equivalent to standard human dose per body surface area. The low doses of 5-FU (10-40 mg/kg) have been shown to have antitumor efficacy in mouse models of cancer. Sham-treated mice received 10% DMSO in sterile water via intraperitoneal injection three times a week via a 26 gauge needle. The injected volumes are calculated to the body weight; the maximum volume does not exceed 200 μL per injection. Mice are euthanized via cervical dislocation at 3 (2 treatments), 7 (3 treatments), and 14 (6 treatments) days after the first injection and colon is collected for in vitro experiments.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

[1]. Han R, et al. Amphiphilic dendritic nanomicelle-mediated co-delivery of 5-fluorouracil and NSC 123127 for enhanced therapeutic efficacy. J Drug Target. 2016 Jun 29:1-28. [Epub ahead of print] [Content Brief]

[2]. Zeng Q, et al. Knockdown of NFBD1/MDC1 enhances chemosensitivity to NSC 119875 or 5-fluorouracil in nasopharyngeal carcinoma CNE1 cells. Mol Cell Biochem. 2016 Jul;418(1-2):137-46. [Content Brief]

[3]. Jones DH, et al. Ten-Year and Beyond Follow-up After Treatment With Highly Purified Liquid-Injectable Silicone for HIV-Associated Facial Lipoatrophy: A Report of 164 Patients. Dermatol Surg. 2019 Jul;45(7):941-948. [Content Brief]

[4]. McQuade RM, et al. Gastrointestinal dysfunction and enteric neurotoxicity following treatment with anticancer chemotherapeutic agent 5-fluorouracil. Neurogastroenterol Motil. 2016 Jun 28. [Content Brief]

[5]. Yin L, et al. Antitumor effects of oncolytic herpes simplex virus type 2 against colorectal cancer in vitro and in vivo. Ther Clin Risk Manag. 2017 Feb 7;13:117-130. [Content Brief]

[6]. Snyder SM, et al. Initial Experience with Topical Fluorouracil for Treatment of HIV-Associated Anal Intraepithelial Neoplasia. J Int Assoc Physicians AIDS Care (Chic). 2011;10(2):83-88. [Content Brief]

[7]. Pek Yee Lum, et al. Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell. 2004 Jan 9;116(1):121-37. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / DMSO / 1 M Ammonium hydroxide	1 mM	7.6876 mL	38.4379 mL	76.8758 mL	192.1894 mL
	5 mM	1.5375 mL	7.6876 mL	15.3752 mL	38.4379 mL
	10 mM	0.7688 mL	3.8438 mL	7.6876 mL	19.2189 mL
	15 mM	0.5125 mL	2.5625 mL	5.1251 mL	12.8126 mL
	20 mM	0.3844 mL	1.9219 mL	3.8438 mL	9.6095 mL
	25 mM	0.3075 mL	1.5375 mL	3.0750 mL	7.6876 mL
	30 mM	0.2563 mL	1.2813 mL	2.5625 mL	6.4063 mL
	40 mM	0.1922 mL	0.9609 mL	1.9219 mL	4.8047 mL
	50 mM	0.1538 mL	0.7688 mL	1.5375 mL	3.8438 mL
	60 mM	0.1281 mL	0.6406 mL	1.2813 mL	3.2032 mL
DMSO / 1 M Ammonium hydroxide	80 mM	0.0961 mL	0.4805 mL	0.9609 mL	2.4024 mL
DMSO / 1 M Ammonium hydroxide	100 mM	0.0769 mL	0.3844 mL	0.7688 mL	1.9219 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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5-Fluorouracil (Synonyms: 5-FU)

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