1. Cell Cycle/DNA Damage
    Anti-infection
    Apoptosis
    Metabolic Enzyme/Protease
  2. Nucleoside Antimetabolite/Analog
    HIV
    Apoptosis
    Endogenous Metabolite
  3. 5-Fluorouracil-15N2

5-Fluorouracil-15N2 

Cat. No.: HY-90006S2
Handling Instructions

5-Fluorouracil-15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer. 5-Fluorouracil also inhibits HIV.

For research use only. We do not sell to patients.

5-Fluorouracil-15N2 Chemical Structure

5-Fluorouracil-15N2 Chemical Structure

CAS No. : 68941-95-7

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Description

5-Fluorouracil-15N2 is the 15N-labeled 5-Fluorouracil. 5-Fluorouracil (5-FU) is an analogue of uracil and a potent antitumor agent. 5-Fluorouracil affects pyrimidine synthesis by inhibiting thymidylate synthetase thus depleting intracellular dTTP pools. 5-Fluorouracil induces apoptosis and can be used as a chemical sensitizer[1][2]. 5-Fluorouracil also inhibits HIV[3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

132.06

Formula

C4H3F15N2O2

CAS No.
SMILES

O=C1C(F)=C[15NH]C([15NH]1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
5-Fluorouracil-15N2
Cat. No.:
HY-90006S2
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