473-86-9
Chemical Structure
3-Hydroxy-2-methylbutanoic acid
- CAS No.: 473-86-9
- Formula:C5H10O3
- Molecular Weight:118.13
IUPAC Name: 3-hydroxy-2-methylbutanoic acid
InChIKey: VEXDRERIMPLZLU-UHFFFAOYSA-N
SMILES: O=C(O)C(C)C(O)C
Biological Activity: 3-Hydroxy-2-methylbutanoic acid is a short-chain carboxylic acid and a normal urinary metabolite produced via isoleucine catabolism, fatty acid β-oxidation and ketogenesis. 3-Hydroxy-2-methylbutanoic acid exists as an acylated residue in resin glycosides derived from plants of the Ipomoea genus. 3-Hydroxy-2-methylbutanoic acid can be used in studies related to β-ketothiolase deficiency[1][2][3].
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3-Hydroxy-2-methylbutanoic acid | 3-Hydroxy-2-methylbutanoic acid is a short-chain carboxylic acid and a normal urinary metabolite produced via isoleucine catabolism, fatty acid β-oxidation and ketogenesis. 3-Hydroxy-2-methylbutanoic acid exists as an acylated residue in resin glycosides derived from plants of the Ipomoea genus. 3-Hydroxy-2-methylbutanoic acid can be used in studies related to β-ketothiolase deficiency. | |||||||||||||||||||||
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- [1]. Heil M, et al. Enantioselective analysis of ketone bodies in patients with beta-ketothiolase deficiency, medium-chain acyl coenzyme A dehydrogenase deficiency and ketonemic vomiting. J Chromatogr B Biomed Sci Appl. 2000;739(2):313-324. [Content Brief]
- [2]. León-Rivera I, et al. Hepta-, hexa-, penta-, tetra-, and trisaccharide resin glycosides from three species of Ipomoea and their antiproliferative activity on two glioma cell lines. Magn Reson Chem. 2017;55(3):214-223. [Content Brief]
- [3]. Fang Y, et al. On the structure of calonyctin A, a plant growth regulator. Carbohydr Res. 1993;245(2):259-270. [Content Brief]
Keywords
