Uric acid-¹⁵N₂

Name: Uric acid- 15 N 2
Brand: MedChemExpress
SKU: HY-B2130S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-B2130S1 Purity: 99.60%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Uric acid-¹⁵N₂ is the ¹⁵N labeled Uric acid. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation.

For research use only. We do not sell to patients.

Uric acid-<sup>15</sup>N<sub>2</sub> Chemical Structure

Uric acid-¹⁵N₂ Chemical Structure

CAS No. : 62948-75-8

Size	Price	Stock	Quantity
1 mg	USD 96	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 288	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 460	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Uric acid-¹⁵N₂:

Uric acid In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Uric acid-¹⁵N₂ is the ¹⁵N labeled Uric acid^[1]. Uric acid, scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. Uric acid can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation^[2]^[3].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

170.10

Formula

C₅H₄N₂¹⁵N₂O₃

CAS No.

62948-75-8

Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=C([15NH]C([15NH]1)=O)NC(N2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

1M NaOH : 8.33 mg/mL (48.97 mM; ultrasonic and warming and adjust pH to 12 with 1M NaOH)

H₂O : 6.25 mg/mL (36.74 mM; ultrasonic and warming and adjust pH to 10 with 1M NaOH)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.8789 mL	29.3945 mL	58.7889 mL
5 mM	1.1758 mL	5.8789 mL	11.7578 mL
10 mM	0.5879 mL	2.9394 mL	5.8789 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.60%

Select Batch:

Data Sheet (275 KB) SDS (251 KB)

COA (250 KB) Elemental Analysis Report (109 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Yasutake Y, et al. Uric acid ameliorates indomethacin-induced enteropathy in mice through its antioxidant activity. J Gastroenterol Hepatol. 2017 Nov;32(11):1839-1845. [Content Brief]

[3]. Wang Q, et al. Recent Progress on Uric Acid Detection: A Review. Crit Rev Anal Chem. 202050(4):359-375. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / 1M NaOH	1 mM	5.8789 mL	29.3945 mL	58.7889 mL	146.9724 mL
	5 mM	1.1758 mL	5.8789 mL	11.7578 mL	29.3945 mL
	10 mM	0.5879 mL	2.9394 mL	5.8789 mL	14.6972 mL
	15 mM	0.3919 mL	1.9596 mL	3.9193 mL	9.7982 mL
	20 mM	0.2939 mL	1.4697 mL	2.9394 mL	7.3486 mL
	25 mM	0.2352 mL	1.1758 mL	2.3516 mL	5.8789 mL
	30 mM	0.1960 mL	0.9798 mL	1.9596 mL	4.8991 mL
1M NaOH	40 mM	0.1470 mL	0.7349 mL	1.4697 mL	3.6743 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.