Galectin-3-IN-4
Galectin-3-IN-4 (compound 5) is a carboxamide analog. Galectin-3-IN-4 is a potent, selective, and orally bioavailable inhibitor of human and mouse galectin-3, with IC50 values of 21 and 167 nM for hGal-3 and mGal-3, respectively. Galectin-3-IN-4 has IC50 values of 1580 and 2750 nM for hGal-1 and hGal-9, respectively.
For research use only. We do not sell to patients.
- CAS No.: 2496515-38-7
- Formula: C24H22ClF2N5O5S
- Molecular Weight:565.98
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Galectin Isoforms
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Biological Activity
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Galectin-3 21 nM (IC50, hGal-3) |
Galectin-3 167 nM (IC50, mGal-3) |
Galectin-1 1580 nM (IC50, hGal-1) |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2496515-38-7
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Molecular Weight 565.98
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Formula C24H22ClF2N5O5S
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SMILES
CO[C@@H]1[C@@H](N2C=C(C3=C(C(F)=C(C=C3)Cl)F)N=N2)[C@H]([C@H](O[C@H]1C(N(C4=CC=C(N=CS5)C5=C4)C)=O)CO)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)