3059548-99-8
Chemical Structure
Gal-1-IN-1
- CAS No.: 3059548-99-8
- Formula:C46H59Cl2F12N8O8P2Ru2S
- Molecular Weight:1446.03
SMILES: [P+5]([F-])([F-])([F-])([F-])([F-])[F-].[Cl-][Ru+2]123456(C=7(C(C)C)[CH]1=[CH]2C3(C)=[CH]4[CH]57)[N]=8C(C=9[N]6=CC=CC9)=CN(N8)[C@@H]%10[C@@H](O)[C@H](S[C@]%11([C@H](O)[C@H]([C@@H](O)[C@@H](CO)O%11)N%12N=[N]%13C(=C%12)C=%14[N]([Ru+2]%13%15%16%17%18%19([Cl-])C=%20(C(C)C)[CH]%15=[CH]%16C%17(C)=[CH]%18[CH]%19%20)=CC=CC%14)[H])O[C@H](CO)[C@@H]%10O
Biological Activity: Gal-1-IN-1 is a potent and selective human galectin-1 (hGal-1) inhibitor with a Ki of 0.022 μM. Gal-1-IN-1 blocks hGal-1 binding to tumor cells and suppresses human galectin-1-induced pre-apoptosis state. Gal-1-IN-1 reduces hGal-1-expressing cancer cell viability. Gal-1-IN-1 can be used for the research of breast cancer[1].
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Gal-1-IN-1 | Gal-1-IN-1 is a potent and selective human galectin-1 (hGal-1) inhibitor with a Ki of 0.022 μM. Gal-1-IN-1 blocks hGal-1 binding to tumor cells and suppresses human galectin-1-induced pre-apoptosis state. Gal-1-IN-1 reduces hGal-1-expressing cancer cell viability. Gal-1-IN-1 can be used for the research of breast cancer. | |||||||||||||||||||||
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Keywords
