Galectin-3/galectin-8-IN-1
Based on 1 Customer Validation
Galectin-3/galectin-8-IN-1 (Compound 53) is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 4.12 μM and 6.04 μM respectively. Galectin-3/galectin-8-IN-1 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-1 can be used for research of cancer and tissue fibrosis.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 3053895-85-2
- Formula: C22H13Cl2N3O4S2
- Molecular Weight:518.39
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
All Galectin Isoforms
More
Biological Activity
|
Galectin-3 |
Galectin-8 |
Chemical Information
-
CAS No. 3053895-85-2
-
Appearance Solid
-
Molecular Weight 518.39
-
Formula C22H13Cl2N3O4S2
-
Color Off-white to light yellow
-
SMILES
O=C(C(N1)=CC2=C1C=CC(OC3=CC=C(Cl)C(Cl)=C3)=C2)NS(=O)(C4=CC=C5N=CSC5=C4)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (48.23 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (271 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9290 mL | 9.6452 mL | 19.2905 mL | 48.2262 mL |
| 5 mM | 0.3858 mL | 1.9290 mL | 3.8581 mL | 9.6452 mL | |
| 10 mM | 0.1929 mL | 0.9645 mL | 1.9290 mL | 4.8226 mL | |
| 15 mM | 0.1286 mL | 0.6430 mL | 1.2860 mL | 3.2151 mL | |
| 20 mM | 0.0965 mL | 0.4823 mL | 0.9645 mL | 2.4113 mL | |
| 25 mM | 0.0772 mL | 0.3858 mL | 0.7716 mL | 1.9290 mL | |
| 30 mM | 0.0643 mL | 0.3215 mL | 0.6430 mL | 1.6075 mL | |
| 40 mM | 0.0482 mL | 0.2411 mL | 0.4823 mL | 1.2057 mL |