Dual Galectin-3/EGFR-IN-1
Dual Galectin-3/EGFR-IN-1 (Compound 29) is the dual inhibitor for Galectin-3 and EGFR with the KD of 52.29 μM and 3.31 μM. Dual Galectin-3/EGFR-IN-1 inhibits TGF-β-induced hepatic stellate cell (HSCs) activation, induces apoptosis in LX-2 cell, and exhibits anti-liver fibrotic efficacy.
For research use only. We do not sell to patients.
- Formula: C32H41N7O10
- Molecular Weight:683.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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EGFR 3.31 μM (Kd) |
Galectin-3 52.29 μM (Kd) |
Chemical Information
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Molecular Weight 683.71
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Formula C32H41N7O10
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SMILES
COCCOC1=CC2=C(N=CN=C2NC3=CC(C4=CN(CCO[C@H]5O[C@@H](CO)[C@@H](O)[C@@H](O)[C@@H]5NC(C)=O)N=N4)=CC=C3)C=C1OCCOC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)