32181-59-2
32181-59-2
Chemical Structure
N-Acetyllactosamine
Synonym(s): N-Acetyl-D-lactosamine
- CAS No.: 32181-59-2
- Formula:C14H25NO11
- Molecular Weight:383.35
IUPAC Name: N-((2R,3R,4S,5R)-3,5,6-trihydroxy-1-oxo-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexan-2-yl)acetamide
InChIKey: HESSGHHCXGBPAJ-ZBELOFFLSA-N
SMILES: O=C[C@H](NC(C)=O)[C@H]([C@@H]([C@@H](CO)O)O[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)O
Biological Activity: N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-Acetyllactosamine | 99.83% | N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects. | ||||||||||||||||||||
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N-Acetyllactosamine (Standard) | ≥98% | N-Acetyllactosamine (Standard) is the analytical standard of N-Acetyllactosamine. This product is intended for research and analytical applications. N-Acetyllactosamine (N-Acetyl-D-lactosamine), a nitrogen-containing disaccharide, is a galectin-3 inhibitor, which is an important component of various oligosaccharides such as glycoproteins and sialyl Lewis X. N-Acetyllactosamine can be used as the starting material for the synthesis of various oligosaccharides. N-Acetyllactosamine has prebiotic effects. | ||||||||||||||||||||
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N,N'-Diacetylchitobiose (Standard) | ≥98% | N,N'-Diacetylchitobiose (Standard) is the analytical standard of N,N'-Diacetylchitobiose. This product is intended for research and analytical applications. N,N'-Diacetylchitobiose is a dimer of β(1,4) linked N-acetyl-D glucosamine. N,N'-Diacetylchitobiose is the hydrolysate of chitin and can be used as alternative carbon source by E. coli. N,N'-Diacetylchitobiose also reverses myocardial depression. | ||||||||||||||||||||
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Lacto-N-biose I | 98.0% | Lacto-N-biose I (Galβ1-3GlcNAc), as an endogenous metabolite, is an acceptor for the α1,2-fucosyltransferase enzyme from Helicobacter pylori. | ||||||||||||||||||||
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Epilactose | 99.89% | Epilactose is an orally active prebiotic disaccharide. Epilactose resists gastrointestinal digestion, stimulates the intestinal epithelium, and induces myosin regulatory light chain phosphorylation, activating the perijunctional actin-myosin ring and paracellular transport. Epilactose produces short-chain fatty acids and organic acids through cecal microbial fermentation, induces paracellular calcium and iron absorption, lowers cecal pH, and increases cecal calcium and magnesium solubility. Epilactose inhibits hepatic cholesterol synthesis. Epilactose can be used for research on osteopenia, colon cancer, Crohn's disease, post-gastrectomy osteopenia and anemia, and obesity. | ||||||||||||||||||||
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D-(+)-Cellobiose-13C | D-(+)-Cellobiose-13C is the 13C labeled D-(+)-Cellobiose. D-(+)-Cellobiose is an endogenous metabolite. | |||||||||||||||||||||
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2-(Acetylamino)-2-deoxy-4-O-β-D-galactopyranosyl-D-galactose | 2-(Acetylamino)-2-deoxy-4-O-β-D-galactopyranosyl-D-galactose is a biochemical assay reagent. | |||||||||||||||||||||
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2-(Acetylamino)-2-deoxy-4-O-(6-deoxy-α-L-galactopyranosyl)-D-glucose | 2-(Acetylamino)-2-deoxy-4-O-(6-deoxy-α-L-galactopyranosyl)-D-glucose (Fuc-α-2-4-GlcNAc) is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology. | |||||||||||||||||||||
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β-D-Galactosyl-(1→3)-N-acetyl-D-galactosamine | 99.29% | β-D-Galactosyl-(1→3)-N-acetyl-D-galactosamine is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology. | ||||||||||||||||||||
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2-(Acetylamino)-2-deoxy-3-O-α-D-galactopyranosyl-D-galactose | 2-(Acetylamino)-2-deoxy-3-O-α-D-galactopyranosyl-D-galactose (GalNAcβ1-3Gal) is a biochemical assay reagent. | |||||||||||||||||||||
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2-(Acetylamino)-2-deoxy-4-O-β-D-mannopyranosyl-D-glucose | 98.0% | 2-(Acetylamino)-2-deoxy-4-O-β-D-mannopyranosyl-D-glucose is a class of biochemical reagents used in glycobiology research. Glycobiology studies the structure, synthesis, biology, and evolution of sugars. It involves carbohydrate chemistry, enzymology of glycan formation and degradation, protein-glycan recognition, and the role of glycans in biological systems. This field is closely related to basic research, biomedicine, and biotechnology. | ||||||||||||||||||||
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N-Allyloxycarbonyl-β-lactosamine | N-Allyloxycarbonyl-β-lactosamine is a biochemical assay reagent. | |||||||||||||||||||||
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References
- [1]. Endo T, Koizumi S, Tabata K, Kakita S, Ozaki A. Large-scale production of N-acetyllactosamine through bacterial coupling. Carbohydr Res. 1999 Mar 31;316(1-4):179-83. [Content Brief]
- [2]. M.Karimi Alavijeh, et al. Simulation and economic assessment of large-scale enzymatic N-acetyllactosamine manufacture. Biochemical Engineering Journal. Volume 154, 15 February 2020, 107459
- [3]. Kojima S, et al. Clostridium botulinum type A progenitor toxin binds to Intestine-407 cells via N-acetyllactosamine moiety. Biochem Biophys Res Commun. 2005 Jun 3;331(2):571-6. [Content Brief]
- [4]. Yoon KT, et al. Galectin-3 inhibits cardiac contractility via a tumor necrosis factor alpha-dependent mechanism in cirrhotic rats. Clin Mol Hepatol. 2022 Apr;28(2):232-241. [Content Brief]
