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Cat. No.: HY-159672

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3D-Monophosphoryl Lipid (12,16)

Name: 3D-Monophosphoryl Lipid (12,16)
Brand: MedChemExpress
SKU: HY-159672
Price: 1100.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 3D-MPL (12,16))

3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) is a TLR4 agonist that can be used as a vaccine adjuvant to enhance the immunogenicity of vaccines.

For research use only. We do not sell to patients.

Formula: C₉₆H₁₈₄N₃O₂₁P
Molecular Weight:1747.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

3D-Monophosphoryl Lipid (12,16) Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

3D-Monophosphoryl Lipid (12,16) (3D-MPL (12,16)) is a TLR4 agonist that can be used as a vaccine adjuvant to enhance the immunogenicity of vaccines^[1].

All Toll-like Receptor (TLR) Isoforms :

Chemical Information

Molecular Weight 1747.47
Formula C₉₆H₁₈₄N₃O₂₁P
SMILES

CCCCCCCCCCCC(O[C@H](CCCCCCCCCCC)CC(N[C@@H]1[C@H]([C@@H]([C@H](O[C@H]1OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O)NC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCCCC)=O)=O)O)O)CO)OP(O)(O)=O)OC(C[C@@H](CCCCCCCCCCC)OC(CCCCCCCCCCCCC)=O)=O)=O)=O.N
Synonyms

3D-MPL (12,16)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Mata-Haro V, et al. The vaccine adjuvant monophosphoryl lipid A as a TRIF-biased agonist of TLR4. Science. 2007 Jun 15;316(5831):1628-32. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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3D-Monophosphoryl Lipid (12,16)

All Toll-like Receptor (TLR) Isoforms