171286-89-8
Chemical Structure
Polyoxyl 40 stearate
Synonym(s): PEG 40 stearate
- CAS No.: 171286-89-8
- Formula:C98H196O42
- Molecular Weight:2046.58
IUPAC Name: 119-hydroxy-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99,102,105,108,111,114,117-nonatriacontaoxanonadecahectyl stearate
InChIKey: SFBZIBQDUNGRMW-UHFFFAOYSA-N
SMILES: O=C(OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO)CCCCCCCCCCCCCCCCC
Biological Activity: Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant formed by the esterification of stearic acid with polyethylene glycol (PEG) containing approximately 40 ethoxy units, it is widely used in pharmaceutical preparations, nanodrug carriers, emulsification systems and biomedical materials. Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal drugs; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Polyoxyl 40 stearate | 98.0% | Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant formed by the esterification of stearic acid with polyethylene glycol (PEG) containing approximately 40 ethoxy units, it is widely used in pharmaceutical preparations, nanodrug carriers, emulsification systems and biomedical materials. Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal drugs; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Polyoxyl 40 stearate (Standard) | ≥98% | Polyoxyl 40 stearate (Standard) is the analytical standard of Polyoxyl 40 stearate (HY-101530B). This product is intended for research and analytical applications. Polyoxyl 40 stearate can be used as an excipient. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Owen J, et al. The Role of PEG-40-stearate in the Production, Morphology, and Stability of Microbubbles. Langmuir. 2019 Aug 6;35(31):10014-10024. [Content Brief]
- [2]. Cassano R, et al. Preparation, characterization and in vitro activities evaluation of solid lipid nanoparticles based on PEG-40 stearate for antifungal drugs vaginal delivery. Drug Deliv. 2016;23(3):1047-56. [Content Brief]
