Polyoxyl 40 stearate
Based on 1 Customer Validation
Polyoxyl 40 stearate (PEG 40 stearate) is a nonionic surfactant formed by the esterification of stearic acid with polyethylene glycol (PEG) containing approximately 40 ethoxy units, it is used in pharmaceutical preparations, nanodrug carriers, emulsification systems and biomedical materials. Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal drugs; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 9004-99-3
- Formula: (C2H4O)nC18H36O2
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
In Vitro
Polyoxyl 40 stearate can serve as a matrix component of solid lipid nanoparticles to achieve controlled release of encapsulated antifungal agents; it can also act as a base material for solid lipid nanoparticles for vaginal administration, and polymerizable groups can be introduced via modification with acryloyl chloride[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 9004-99-3
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Appearance Solid
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Formula (C2H4O)nC18H36O2
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Color White to off-white
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SMILES
O=C(OCCO)CCCCCCCCCCCCCCCCC.[40]
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Synonyms
PEG 40 stearate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 175 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
[1]. Owen J, et al. The Role of PEG-40-stearate in the Production, Morphology, and Stability of Microbubbles. Langmuir. 2019 Aug 6;35(31):10014-10024. [Content Brief]
[2]. Cassano R, et al. Preparation, characterization and in vitro activities evaluation of solid lipid nanoparticles based on PEG-40 stearate for antifungal drugs vaginal delivery. Drug Deliv. 2016;23(3):1047-56. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)