61791-12-6
61791-12-6
Chemical Structure
Cremophor EL-40
Synonym(s): Polyoxyethylene(40) Castor Oil; PEG-40 Castor Oil
- CAS No.: 61791-12-6
- Formula:N/A
- Molecular Weight:N/A
SMILES: [Cremophor EL-40]
Biological Activity: Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cremophor EL-40 | 99.59% | Cremophor EL-40, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-40 is widely employed to improve dissolution and delivery of agents. | ||||||||||||||||||||
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Cremophor EL-90 | Cremophor EL-90, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-90 has good emulsifying properties. | |||||||||||||||||||||
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Cremophor EL-60 | Cremophor EL-60, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-60 has good emulsifying properties. | |||||||||||||||||||||
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Cremophor EL-20 | Cremophor EL-20 is a type of Cremophor EL. Cremophor EL is a nonionic surfactant. | |||||||||||||||||||||
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Cremophor EL-36 | Cremophor EL-36 is a non-ionic surfactant, mainly used as a solubilizing carrier for poorly soluble Paclitaxel (HY-B0015). For example, Cremophor EL-36 can enhance the intracellular influx of Etoposide (HY-13629) without affecting drug efflux, and can dose-dependently increase the accumulation of VP-16 in lung adenocarcinoma cells (such as PC-14 and A549), significantly enhancing its cytotoxic effect. | |||||||||||||||||||||
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Cremophor EL-80 | Cremophor EL-80, a polyoxyethylene castor oil derivative, is a nonionic surfactant. Cremophor EL-80 has good emulsifying properties. | |||||||||||||||||||||
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Cremophor EL-10 | Cremophor EL-10 is a nonionic polyoxyethylene castor oil surfactant with multiple functions including organic solubilizer, mixed zinc anode corrosion inhibitor and dendrite growth inhibitor. By forming a physical barrier to block electrolyte contact and constructing oriented hydration channels to reduce the desolvation energy barrier of Zn2+ , Cremophor EL-10 achieves a corrosion inhibition efficiency of over 99%. Cremophor EL-10 exerts no significant effects on the mitochondrial activity and cell viability of epithelial cells, making it suitable for in vitro drug delivery and biopharmaceutical research at concentrations ≤10% v/v. However, Cremophor EL-10 may induce sustained non-endothelium-dependent contraction in rat aortic rings and exert concentration-dependent inhibitory effects on acetylcholine-induced endothelium-dependent relaxation responses. | |||||||||||||||||||||
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