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Benzalkonium chloride (51% in water)

Name: Benzalkonium chloride (51% in water)
Brand: MedChemExpress
SKU: HY-B2232
Price: 50.00 USD
Availability: InStock
Rating: 5 (2 reviews)

(Synonyms: Alkyldimethylbenzylammonium chloride)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Benzalkonium (Alkyldimethylbenzylammonium) chloride (51% in water) is a quaternary ammonium preservative, cationic surfactant, and antimicrobial (Antimicrobial) agent. Benzalkonium chloride (51% in water) is toxic.

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Pureza : 98.0%
No. CAS: 8001-54-5
Fòrmula: C₆H₅CH₂N(CH₃)2RCl (R=C₈H₁₇ to C₁₈H₃₇)
Peso molecular:283.88-424.15

Almacenamiento:

Solution, -20°C, 2 years

Benzalkonium chloride (51% in water) Chemical Structure

No. CAS: 8001-54-5

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Actividad biológica

Descripciòn

In Vivo

Benzalkonium chloride (51% in water) (1.19-11.9 μg/cm²; intranasal administration; 8 times daily) exhibits dose-dependent nasal epithelial toxicity in Wistar rats: no effect is observed at the dose of 1.19 μg/cm², mild to moderate damage occurs at 5.97 μg/cm², and more severe damage is seen at 11.9 μg/cm²^[1].
Benzalkonium chloride (51% in water) (0.001%; intranasal administration; twice daily; 14 to 28 days) induces nasal epithelial degeneration in rabbits^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Rabbits^[1]
Dosage:

0.001%;
Administration:

intranasal; twice daily; 14 or 28 days
Result:

Induced degenerative changes, including squamous cell metaplasia, nuclei deformation, and increased heterochromatin, in the treated nasal epithelium.

Chemical Information

No. CAS 8001-54-5
Appearance Liquid
Peso molecular 283.88-424.15
Fòrmula C₆H₅CH₂N(CH₃)2RCl (R=C₈H₁₇ to C₁₈H₃₇)
Color Colorless to light yellow
SMILES

C[N+](C[(CH2)nCH3])(C)CC1=CC=CC=C1.[Cl-].[n=].[6 -16]
Synonyms

Alkyldimethylbenzylammonium chloride
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Solution, -20°C, 2 years

Publications (2)

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ACS Biomater Sci Eng

Mechanoresponsive Drug Loading System with Tunable Host-Guest Interactions for Ocular Disease Treatment. [Abstract]

2022 Nov 14;8(11):4850-4862. PMID: 36214483
Int J Ophthalmol

Obtusifolin ameliorates dry eye model in rats by reducing inflammation and blocking MAPK/NF-κB pathways. [Abstract]

2025 Aug 18;18(8):1426-1432. PMID: 40827285

Pureza y Documentación

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Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (271 KB)
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COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
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Instrucciones de manejo (2659 KB)

Referencias

[1]. Johnson NF. Pulmonary Toxicity of Benzalkonium Chloride. J Aerosol Med Pulm Drug Deliv. 2017 Jul 6. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Benzalkonium chloride (51% in water)

2 Cited Publications

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Benzalkonium chloride (51% in water)

Publications Citing Use of MedChemExpress (MCE) Benzalkonium chloride (51% in water)