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Cat. No.: HY-133727

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Terfenadine N-oxide

Terfenadine N-oxide, an N-oxide derivative of Terfenadine (HY-B1193), is a histamine H1 receptor antagonist (IC₅₀ = 2.73 μM) and an hERG potassium channel inhibitor (IC₅₀ = 0.698 μM). Terfenadine N-oxide is can be used for the research of histamine-related allergic diseases and hERG channel-associated arrhythmias.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 634901-83-0
화학식: C₃₂H₄₁NO₃
분자량:487.67

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Terfenadine N-oxide Chemical Structure

CAS No.: 634901-83-0

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

IC₅₀ & Target

^[1]

H₁ Receptor

2.73 μM (IC₅₀)

All Histamine Receptor Isoforms :

In Vitro

Terfenadine N-oxide (Compound Comparative Example D) shows IC₅₀ values of 2.73 and 0.698 μmM for Histamine H1 receptor and hERG^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 634901-83-0
분자량 487.67
화학식 C₃₂H₄₁NO₃
SMILES

[O-][N+]1(CCC(C(C2=CC=CC=C2)(C3=CC=CC=C3)O)CC1)CCCC(C4=CC=C(C(C)(C)C)C=C4)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Robert George Boyle, et al. N-oxide-containing pharmaceutical compounds. WO2008139152A1. 2009-11-11

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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