Terfenadine N-oxide
Terfenadine N-oxide, an N-oxide derivative of Terfenadine (HY-B1193), is a histamine H1 receptor antagonist (IC50 = 2.73 μM) and an hERG potassium channel inhibitor (IC50 = 0.698 μM). Terfenadine N-oxide is can be used for the research of histamine-related allergic diseases and hERG channel-associated arrhythmias.
For research use only. We do not sell to patients.
- CAS No.: 634901-83-0
- Formula: C32H41NO3
- Molecular Weight:487.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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H1 Receptor 2.73 μM (IC50) |
Terfenadine N-oxide (Compound Comparative Example D) shows IC50 values of 2.73 and 0.698 μmM for Histamine H1 receptor and hERG[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 634901-83-0
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Molecular Weight 487.67
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Formula C32H41NO3
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SMILES
[O-][N+]1(CCC(C(C2=CC=CC=C2)(C3=CC=CC=C3)O)CC1)CCCC(C4=CC=C(C(C)(C)C)C=C4)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Terfenadine N-oxide Related Classifications
HY-133727 Related Classifications
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