2. Recombinant Proteins
  3. Cytokines and Growth Factors Receptor Proteins
  4. Chemokine & Receptors G-Protein-Coupled Receptors (GPCRs)
  5. CXC Chemokine Receptor Chemokine Receptor
  6. CXCR7

CXCR7

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Cat. No. Product Name / Synonyms Species Source
  • HY-P700537
    ACKR3 Protein, Human (His-SUMO)

    RDC1; CXCR7; RDC-1; CMKOR1; CXC-R7; CXCR-7; GPR159;

    		Human E. coli
    ACKR3, an atypical chemokine receptor, precisely controls chemokine levels and localization through high-affinity binding, operating independently of ligand-driven signal transduction. It serves as an interceptor, internalizing receptor, and chemokine-scavenger for CXCL11 and CXCL12/SDF1, inducing beta-arrestin recruitment, ligand internalization, and MAPK pathway activation. Essential for regulating CXCR4 in interneurons and promoting survival in glioma cells, ACKR3 also influences malignant hematopoietic cell adhesion and migration. Its regulatory roles extend to heart valve development, axon guidance, and HIV infection collaboration with CXCR4. ACKR3 Protein, Human (His-SUMO) is the recombinant human-derived ACKR3 protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of ACKR3 Protein, Human (His-SUMO) is 40 a.a., with molecular weight of 20.5 kDa.
  • HY-P702198
    ACKR3 Protein, Human (Cell-Free, His, SUMO)

    Atypical chemokine receptor 3; C-X-C chemokine receptor type 7; CXC-R7; CXCR-7; Chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; RDC-1

    		Human E. coli Cell-free
    ACKR3 is an atypical chemokine receptor that precisely controls chemokine levels and localization through high-affinity binding, operating independently of ligand-driven signaling. It acts as an interceptor, internalization receptor, and chemokine scavenger for CXCL11 and CXCL12/SDF1, inducing β-arrestin recruitment, ligand internalization, and MAPK pathway activation. ACKR3 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived ACKR3 protein, expressed by E. coli Cell-free , with N-6*His, N-SUMO labeled tag. The total length of ACKR3 Protein, Human (Cell-Free, His, SUMO) is 362 a.a., with molecular weight of 57.5 kDa.
Cat. No. Product Name Effect Purity