Adenylosuccinic acid
Based on 1 Customer Validation
Adenylosuccinic acid (Adenylosuccinate; Aspartyl adenylate) is a purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid has the potential for the study of duchenne muscular dystrophy(DMD).
For research use only. We do not sell to patients.
- Purity: 99.74%
- CAS No.: 19046-78-7
- Formula: C14H18N5O11P
- Molecular Weight:463.29
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
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Human Endogenous Metabolite |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57Bl/10ScSn (normal wild-type strain; Con) and C57Bl/10mdx (mdx) mice[1]
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Dosage:3 µg/mL, 30 µg/mL, 300 µg/mL, 3000 µg/mL
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Administration:3 µg/mL for 3 days and 30 µg/mL for the next 4 days, and 300 µg/mL for one week, and then 3000 µg/mL for 6 weeks
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Result:Ameliorated the symptoms of murine duchenne muscular dystrophy.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 19046-78-7
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Appearance Solid
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Molecular Weight 463.29
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Formula C14H18N5O11P
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Color White to off-white
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SMILES
O=C(C[C@H](NC1=C2N=CN(C2=NC=N1)[C@H]3[C@H](O)[C@H](O)[C@H](O3)COP(O)(O)=O)C(O)=O)O
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Synonyms
Adenylosuccinate; Aspartyl adenylate
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : ≥ 50 mg/mL (107.92 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1585 mL | 10.7924 mL | 21.5848 mL | 53.9619 mL |
| 5 mM | 0.4317 mL | 2.1585 mL | 4.3170 mL | 10.7924 mL | |
| 10 mM | 0.2158 mL | 1.0792 mL | 2.1585 mL | 5.3962 mL | |
| 15 mM | 0.1439 mL | 0.7195 mL | 1.4390 mL | 3.5975 mL | |
| 20 mM | 0.1079 mL | 0.5396 mL | 1.0792 mL | 2.6981 mL | |
| 25 mM | 0.0863 mL | 0.4317 mL | 0.8634 mL | 2.1585 mL | |
| 30 mM | 0.0719 mL | 0.3597 mL | 0.7195 mL | 1.7987 mL | |
| 40 mM | 0.0540 mL | 0.2698 mL | 0.5396 mL | 1.3490 mL | |
| 50 mM | 0.0432 mL | 0.2158 mL | 0.4317 mL | 1.0792 mL | |
| 60 mM | 0.0360 mL | 0.1799 mL | 0.3597 mL | 0.8994 mL | |
| 80 mM | 0.0270 mL | 0.1349 mL | 0.2698 mL | 0.6745 mL | |
| 100 mM | 0.0216 mL | 0.1079 mL | 0.2158 mL | 0.5396 mL |
Adenylosuccinic acid Related Classifications
HY-127137 Related Classifications
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