Adenylosuccinic acid tetraammonium
Based on 1 Customer Validation
Adenylosuccinic acid tetraammonium (Adenylosuccinate; Aspartyl adenylate) is an orally active purine ribonucleoside monophosphate and plays a role in nucleotide cycle metabolite. Adenylosuccinic acid tetraammonium can be converted into fumaric acid through adenylosuccinate lyase. Adenylosuccinic acid tetraammonium has the potential for the study of duchenne muscular dystrophy(DMD).
For research use only. We do not sell to patients.
- Purity : 98.0%
- Formula: C14H30N9O11P
- Molecular Weight:531.42
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
IC50 & Target
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Human Endogenous Metabolite |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57Bl/10ScSn (normal wild-type strain; Con) and C57Bl/10mdx (mdx) mice[1]
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Dosage:3 µg/mL, 30 µg/mL, 300 µg/mL, 3000 µg/mL
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Administration:3 µg/mL for 3 days and 30 µg/mL for the next 4 days, and 300 µg/mL for one week, and then 3000 µg/mL for 6 weeks
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Result:Ameliorated the symptoms of murine duchenne muscular dystrophy.
Chemical Information
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Appearance Solid
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Molecular Weight 531.42
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Formula C14H30N9O11P
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Color White to off-white
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SMILES
O=C(C[C@H](NC1=C2N=CN(C2=NC=N1)[C@H]3[C@H](O)[C@H](O)[C@H](O3)COP(O)(O)=O)C(O)=O)O.N.N.N.N
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Synonyms
Adenylosuccinate tetraammonium; Aspartyl adenylate tetraammonium
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 200 mg/mL (376.35 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.8818 mL | 9.4088 mL | 18.8175 mL | 47.0438 mL |
| 5 mM | 0.3764 mL | 1.8818 mL | 3.7635 mL | 9.4088 mL | |
| 10 mM | 0.1882 mL | 0.9409 mL | 1.8818 mL | 4.7044 mL | |
| 15 mM | 0.1255 mL | 0.6273 mL | 1.2545 mL | 3.1363 mL | |
| 20 mM | 0.0941 mL | 0.4704 mL | 0.9409 mL | 2.3522 mL | |
| 25 mM | 0.0753 mL | 0.3764 mL | 0.7527 mL | 1.8818 mL | |
| 30 mM | 0.0627 mL | 0.3136 mL | 0.6273 mL | 1.5681 mL | |
| 40 mM | 0.0470 mL | 0.2352 mL | 0.4704 mL | 1.1761 mL | |
| 50 mM | 0.0376 mL | 0.1882 mL | 0.3764 mL | 0.9409 mL | |
| 60 mM | 0.0314 mL | 0.1568 mL | 0.3136 mL | 0.7841 mL | |
| 80 mM | 0.0235 mL | 0.1176 mL | 0.2352 mL | 0.5880 mL | |
| 100 mM | 0.0188 mL | 0.0941 mL | 0.1882 mL | 0.4704 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Adenylosuccinic acid tetraammonium Related Classifications
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