D-Fructose-6-phosphate disodium
Based on 1 Customer Validation
D-Fructose 6-phosphate disodium is an endogenous metabolite. D-Fructose 6-phosphate disodium can be obtained by hydrolysis of Fructose-1,6-bisphosphatase (FBPase). D-Fructose-6-phosphate disodium is a sugar intermediate in the glycolysis pathway and the pentose phosphate pathway. D-Fructose-6-phosphate disodium can be used to detect glucosamine-6-phosphate synthase and TAL activities. D-Fructose 6-phosphate disodium can be used to study Lewy body dementia.
For research use only. We do not sell to patients.
- Purity: 99.92%
- CAS No.: 26177-86-6
- Formula: C6H11Na2O9P
- Molecular Weight:304.10
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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All Endogenous Metabolite Isoforms
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Biological Activity
D-Fructose-6-phosphate (3.2 mM; room temperature) disodium can detect transaldolase TAL activity[3].
D-Fructose-6-phosphate (10 mM; incubation at 37°C for 60 min) disodium can complete the detection of glucosamine-6-phosphate synthase activity[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 26177-86-6
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Appearance Solid
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Molecular Weight 304.10
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Formula C6H11Na2O9P
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Color White to off-white
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SMILES
OCC([C@H]([C@@H]([C@@H](COP(O[Na])(O[Na])=O)O)O)O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (328.84 mM; Need ultrasonic)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (328.84 mM); Clear solution; Need ultrasonic
Purity & Documentation
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Data Sheet (272 KB)
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SDS (419 KB)
- English - EN (419 KB)
- Français - FR (419 KB)
- Deutsch - DE (419 KB)
- Norwegian - NO (419 KB)
- Español - ES (419 KB)
- Swedish - SV (419 KB)
- Italian - IT (419 KB)
- Korean - KR (419 KB)
- Portuguese - PT (419 KB)
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Handling Instructions (2659 KB)
References
[1]. Lee JH, et al. Crystal structure of rabbit phosphoglucose isomerase complexed with its substrate D-fructose 6-phosphate. Biochemistry. 2001 Jul 3;40(26):7799-805. [Content Brief]
[2]. Hardie DG, et al. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012 Mar 22;13(4):251-62. [Content Brief]
[3]. Puskas F, et al. Stimulation of the pentose phosphate pathway and glutathione levels by dehydroascorbate, the oxidized form of vitamin C. FASEB J. 2000 Jul;14(10):1352-61. [Content Brief]
[4]. Hiramatsu M, et al. Suppression by thyroid hormones of glucosamine-6-phosphate synthetase activity in rat sublingual glands. Arch Oral Biol. 1984;29(10):849-51. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.2884 mL | 16.4420 mL | 32.8839 mL | 82.2098 mL |
| 5 mM | 0.6577 mL | 3.2884 mL | 6.5768 mL | 16.4420 mL | |
| 10 mM | 0.3288 mL | 1.6442 mL | 3.2884 mL | 8.2210 mL | |
| 15 mM | 0.2192 mL | 1.0961 mL | 2.1923 mL | 5.4807 mL | |
| 20 mM | 0.1644 mL | 0.8221 mL | 1.6442 mL | 4.1105 mL | |
| 25 mM | 0.1315 mL | 0.6577 mL | 1.3154 mL | 3.2884 mL | |
| 30 mM | 0.1096 mL | 0.5481 mL | 1.0961 mL | 2.7403 mL | |
| 40 mM | 0.0822 mL | 0.4110 mL | 0.8221 mL | 2.0552 mL | |
| 50 mM | 0.0658 mL | 0.3288 mL | 0.6577 mL | 1.6442 mL | |
| 60 mM | 0.0548 mL | 0.2740 mL | 0.5481 mL | 1.3702 mL | |
| 80 mM | 0.0411 mL | 0.2055 mL | 0.4110 mL | 1.0276 mL | |
| 100 mM | 0.0329 mL | 0.1644 mL | 0.3288 mL | 0.8221 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Fructose-6-phosphate disodium Related Classifications
HY-113407A Related Classifications
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